洪凱風 助理教授(Kai-Feng Hung, DDS, PhD) 

個人簡歷

學歷

/肄業學校

國別

主修系別

學位

畢業年度

台北醫學大學

台灣

牙醫學系

學士

2000

國立陽明交通大學

台灣

臨床牙醫研究所

碩士

2004

華盛頓大學

美國

口腔生物學系

博士

2014

經歷

服務單位

服務部門

職稱

服務期間

國立陽明交通大學附設醫院

口腔顎面外科

主治醫師

2016-2017

台北慈濟綜合醫院

口腔顎面外科

主治醫師

20052009

國立陽明交通大學

牙醫學系

兼任講師

20052009

台北榮民總醫院

口腔醫學部口腔顎面外科

住院醫師

20002005

 

現職:
台北榮民總醫院醫學研究部轉譯研究科     研究醫師

台北榮民總醫院口腔醫學部口腔顎面外科     主治醫師
國立陽明交通大學牙醫學院牙醫學系              助理教授

專長口腔顎顏面外科、腫瘤分子生物學

聯絡電話(02) 28712121-7382

電子郵件kaifenghung@ym.edu.tw

研究方向

細胞內DNA損害反應(DNA damage response)DNA損害後複製修復(post-replication repair) 、癌症免疫治療 (Cancer immunology)

期刊論文

 Original Research

1.         Hung KF, Sidorova JM, Nghiem P, Kawasumi M. (2020, May). The 6-4 Photoproduct Is the Trigger of UV-induced Replication Blockage and ATR Activation. Proceedings of the National Academy of Sciences of the United States of America, doi: 10.1073/pnas.1917196117. 本人為第一作者.

2.         CY Chen, Kawasumi M, Lan TY, Poon CL, Lin YS, Wu PJ, Chen YC, Chen BH, Wu CH, Lo JF, Weng RR, Sun YC, Hung KF. (2020, December). Adaptation to endoplasmic reticulum stress enhances resistance of oral cancer cells to cisplatin by up-regulating polymerase η and increasing DNA repair efficiency. Int. J. Mol. Sci. Acceptance. 本人為通訊作者.

3.         Hung KF, Liao PC, Chen CK, Chiu YT, Cheng DH, Kawasumi M, Kao SY, Lo JF (2019, Apr). ASB6 Promotes the Stemness Properties and Sustains Metastatic Potential of Oral Squamous Cell Carcinoma Cells by Attenuating ER Stress. International Journal of Biological Sciences, 15(5):1080-1090. MOST 106- 2314-B-075-077-MY3. 本人為第一作者.

4.         Hung KF, Sun YC, Chen BH, Lo JF, Cheng CM, Chen CY, Wu CH, Kao SY. (2020, Oct). New COVID-19 saliva-based test: How good is it compared with the current nasopharyngeal or throat swab test? Journal of the Chinese Medical Association, 83(10):891-894. 本人為第一作者.

5.         Hung KF, Sun YC, Liou HM, Hu FR (2019, Jun). Human antigen R protein modulates vascular endothelial growth factor expression in human corneal epithelial cells under hypoxia. Journal of the Formosan Medical Association, S0929-6646(19)30217-7. 本人為第一作者.

6.         Hung KF, Yang T, Kao SY (2019, Nov). Cancer stem cell theory: Are we moving past the mist? Journal of the Chinese Medical Association, 82(11):814-818. 本人為第一作者.

7.         Liao WT, Hsu MY, Shen CF, Hung KF, Cheng CM (2020, Nov). Home Sample Self-Collection for COVID-19 Patient. Advanced Biosystems, (11): e2000150. 本人為共同通訊作者.

8.         Chou CJ, Lin CF, Chen YW, Huang PI, Yang YP, Wang ML, Hung KF, Lee YY (2020, May). The update of chimeric antigen receptor-T cells therapy in glioblastoma. Journal of the Chinese Medical Association, 83(5):442-445.

9.         Lin WY, Chen YW, Lin CF, Yang YP, Wang ML, Hung KF, Huang PI, Lee YY, Chiou SH (2020, Aug). Emerging trends in gene-modified-based chimeric antigen receptor-engineered T-cellular therapy for malignant tumors: The lesson from leukemia to pediatric brain tumors. Journal of the Chinese Medical Association, 83(8):719-724.

10.     Akbor M, Hung KF, Yang YP, Chou SJ, Tsai PH, Chien CS, Lin LT (2019, Dec). Immunotherapy orchestrates radiotherapy in composing abscopal effects: A strategic review in metastatic head and neck cancer. Journal of the Chinese Medical Association, 83(2):113-116.

11.     Lee JW, Ratnakumar K, Hung KF, Rokunohe D, Kawasumi M (2020, Mar). Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer. Photochemistry and Photobiology, doi: 10.1111/php.13245.

12.     Chen YS, Chang CW, Tsay YG, Huang LY, Wu YC, Cheng LH, Yang CC, Wu CH, Teo WH, Hung KF, Huang CY, Lee TC, Lo JF (2018, Jun). HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling. Theranostics, 8(14):3841-3855.

13.     Chang CW, Chen YS, Tsay YG, Han CL, Chen YJ, Yang CC, Hung KF, Lin CH, Huang TY, Kao SY, Lee TC, Lo JF (2018, Feb). ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells. Cell Death & Disease, 9(2):194.

14.     Cheng LH, Hung KF, Lee TC, Huang CY, Chiu WT, Lo JF, Huang TF (2016, Dec). Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis. Stem Cell Research & Therapy, 7(1), 185-194.

15.     Cheng LH, Hung KF, Huang TF, Hsieh HP, Wang SY, Huang CY, Lo JF (2016, Oct). Attenuation of Cancer-Initiating Cells Stemness Properties by Abrogating S100A4 Calcium Binding Ability in Head and Neck Cancers. Oncotarget, 7(48), 78946-78957.

16.      Hung KF, Liu CJ, Chiu PC, Lin JS, Chang KW, Shi WY, Kao SY, Tu HF. MicroRNA-31 upregulation predicts increased risk of progression of Oral Potentially Malignant Disorder. Oral Oncol. 53:42-7, 2016.

17.      Cheng LH, Hung KF, Huang TF, Hsieh HP, Wang SY, Huang CY, Lo JF. Attenuation of Cancer-Initiating Cells Stemness Properties by Abrogating S100A4 Calcium Binding Ability in Head and Neck Cancers. Oncotarget. 7(48): 78946- 57, 2016.

18.      Cheng LH, Hung KF, Lee TC, Huang CY, Chiu WT, Lo JF, Huang TF. Mitochondrial cochaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis. Stem Cell Res Ther. 7(1): 185-94, 2016.

19.      Hung KF, Lai KC, Liu TY, Liu CJ, Lee TC, Lo JF. Asb6 upregulation by Areca nut extracts is associated with betel quid-induced oral carcinogenesis. Oral Oncol. 45(6):543-8, 2009.

20.      Fong Y, Chou SJ, Hung KF, Wu HT, Kao SY. An investigation of the differential expression of Her2/neu gene expression in normal oral mucosa, epithelial dysplasia, and oral squamous cell carcinoma in Taiwan. J Chin Med Assoc. 71(3):123-7, 2008.

21.      Hung KF, Chang CS, Liu CJ, Lui MT, Cheng CY, Kao SY. Differential expression of E-cadherin in metastatic lesions comparing to primary oral squamous cell carcinoma. J Oral Pathol Med. 35(10):589-94, 2006.

22.      Hung KF, Lin SC, Liu CJ, Chang CS, Chang KW, Kao SY. The biphasic differential expression of the cellular membrane protein, caveolin-1, in oral carcinogenesis. J Oral Pathol Med. 32(8):461-7, 2003.

 

Case Reports:

1.   Liaw YC, Kuang SH, Chen YW, Hung KF, Tsai HC, Kao SY, Fong JH. Multimodality treatment for rehabilitation of adult orthodontic patient with complicated dental condition and jaw relation. J Chin Med Assoc. 71(11):594-600, 2008.

2.   Kao SY, Lui MT, Fong J, Wu DC, Wu CH, Tu HF, Hung KF, Yeung TC. A method using vestibulo-sulcoplasty combining a split-thickness skin graft and a palatal keratinized mucosa graft for peri-implant tissue secondary to oral cancer surgery. J Oral Implantol. 31(4):186-91, 2005.

3.   Kao SY, Yeung TC, Hung KF, Chou IC, Wu CH, Chang RC. Transpositioned flap vestibuloplasty combined with implant surgery in the severely resorbed atrophic edentulous ridge. J Oral Implantol. 28(4):194-9, 2002.

 

 

 

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