于耀華 助理教授 (Yau-Hua Yu)
個人簡歷

學歷
DDS   1992-1998 牙醫學學士‚國立陽明大學
DMSc 2001-2005 醫學科學博士 (牙科生物資訊)
          美國哈佛大學牙醫學院
經歷
國立陽明大學學士
台北榮民總醫院牙科住院醫師
國立陽明大學助理教授
台北榮民總醫院教研部特約副研究員
台北市立聯合醫院聘兼助理研究員
台北榮民總醫院牙科進修醫師
專長:生物醫學資訊老年牙周病
Network biology in Head and Neck Squamous Cell Carcinoma (HNSCC)Periodontal disease in the elderly

Aging phenotypes in the elderly
Systematic reviews and Meta-analysis
Computational biology, Systems biology, and Stem cell biology

聯絡電話2826-7247
傳真:886-2-28264053
電子郵件yhyu@ym.edu.tw  or  yauhuayu@gmail.com
 
研究方向
Integrative meta-methods and biological networks provide insights in depicting gene-gene interplays and modeling human diseases at systems-level. A network-based meta-analysis to include transcriptomic studies of HNSCC into progressive comparisons will highlight the evolving nature of HNSCC. Furthermore, topological network analyses are to reveal significant genes and enriched disruptive signaling pathways. Thus, the evolving nature of the HNSCC transcriptome could be deciphered via the analyzed topological characteristics and the prismatic visualization of the interacting networks in the progressive stages.
研究計畫

PI            2006-2007
The Evolving Transcriptome of Head and Neck Squamous Cell Carcinoma
Aim for the Top University Plan, Ministry of Education, Taiwan

Co-PI     2007
Cerebrovascular Correlates of Physical Performance and Cognitive Function in Old Age: a Focus on Carotid Atherosclerosis, Cerebral White Matter Changes (Leukoaraiosis), and Geriatric Syndromes. 
GE-095-CP0 National Health Research Institutes, Taiwan

發表著作

1.  Sebastiani P, Yu YH, Ramoni MF*. Bayesian machine learning and its potential applications to the genomic study of oral oncology. Adv Dent Res. 2003 Dec;17:104-8

2.  Yu YH*. Integrative Genomics of Squamous Cell Carcinoma in the Oral Cavity, Pharynx, and Larynx. Thesis dissertation, 2005, Harvard School of Dental Medicine, Boston MA

3.  Kuo HK, Yen CJ, Chen JH, Yu YH*, Bean J. Association of cardiorespiratory fitness and levels of C-reactive protein: Data from the National Health and Nutrition Examination Survey (NHANES) 1999-2002. Int J Cardiol. 2007 Jan 2;114(1):28-33. Epub 2006 May 5.

4.  Kuo HK, Leveille SG, Yen CJ*, Chai HM, Chang CH, Yeh YC, Yu YH, Bean JF. Exploring How Peak Leg Power and Usual Gait Speed Are Linked to Late-life Disability: Data From the National Health and Nutrition Examination Survey (NHANES) 1999-2002. Am J Phys Med Rehabil. 2006 Aug;85(8):650-658.

5.      Kuo HK, Leveille SG, Yu YH*, Milberg WP. Cognitive Performance, Habitual Gait Speed, and Late-Life Disability in the National Health and Nutrition Examination Survey (NHANES) 1999-2002. Gerontology. 2007;53(2):102-10. Epub 2006 Nov 6.

6.  Yu YH, Kuo HK*, Lai YL. Levels of Serum Folic Acid Are Associated with Periodontal Disease in Older Adults. J Am Geriatr Soc. 2007 Jan;55(1):108-13.

7.      Kuo HK, Liao KC, Leveille SG, Bean JF, Yen CJ, Chen JH, Yu YH*, Tai TY. The relations of homocysteine levels to quadriceps strength, gait speed, and late-life disability in older adults. Journal of Gerontology: MEDICAL SCIENCES. 2007 Apr;62(4):434-9.

8.  Kuo HK, Yu YH*. The Relation of Peripheral Arterial Disease to Leg Force, Gait Speed, and Functional Dependence Among Older Adults. The Journal of Gerontology: Medical Sciences. 2007 Apr;62(4):434-9.

9.  Kuo HK*, Lin LY, Yu YH. Microalbuminuria is a negative correlate for cognitive function in older adults with peripheral arterial disease: results from the U.S. National Health and Nutrition Examination Survey 1999-2002. Journal of Internal Medicine. 2007 Nov;262(5):562-70

10. Huang TS, Hsieh JY, Wu YH, Jen CH, Tsuang YH, Chiou SH, Partanen J, Anderson H, Jaatinen T, Yu YH, Wang HW*. Functional Network Reconstruction Reveals Somatic Stemness Genetic Maps and Dedifferentiation-Like Transcriptome Reprogramming Induced by GATA2. Stem Cells. 2008 Feb 28; [Epub ahead of print]

 

 

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