Dr. Ching-Yuang Lin, Professor

Changhua Christian Hospital
Phone: 886-4-723-8595 #1901
E-mail: 100966@cch.org.tw


1974, M.D.@ China Medical College, Taiwan

1982, Ph.D.@National Osaka University, Japan

1984@@@@Postdoctoral Fellow
@@@@@@ Medical College of Virginia, USA



1. Lin CY, Ku FM, Kuo YC, Chen CF, Chen WP, Chen A, Shiao MS 1999 Inhibition of activated human mesangial cells proliferation by the natural product of Cordyceps sinensis (H1-A): Am implication for treatment of IgA mesangial nephropathy. J Lab Clin Med 133:55-63. (Sci)

2. Kuo YC, Sun CM, Tsai WJ, Ou JC, Chen WP, Lin CY 1999 Blocking of cell proliferation, cytokines production and genes expression following administration of Chinese herbs in the human mesangial cells. Life Sci 64:2089-2099. (Sci)

3. Yang LY, Chen A, Kuo YC, Lin CY 1999 The efficacy of a pure compound H1-A extracted from Cordyceps Sinensis on autoimmune disease of MRL lpr/lpr mice. J Lab Clin Med 134:492-500. (Sci)

4. Lin CC, Lin CY, Ma HY 2000 Pulmonary function changes and increased Th-2 expression and nuclear factor eB activation in the lung after sensitization and allergen challenge in brown norway rats. Immunol Lett 73:57-64. (Sci)

5. Lin CY, Sheng CC, Chen CH, Lin CC, Chou P 2000 The prevalence of heavy proteinuria and risk factors of progression in urinary screening children. Pediatr Nephrol 14:953-959. (Sci)

6. Loong CC, Lin CY, Lui WY 2000 Expression of interleukin-17 as a predictive parameter in acute renal allograft rejection. Transplant P 32:1773. (Sci)

7. Kuo YC, Tsai WJ, Wang JY, Chang SC, Lin CY, Shiao MS 2001 Regulation of bronchoalveolar lavage fluids cell function by the immunomodulatory agents from Cordyceps sinensis. Life Sci 68:1067-1082. (Sci)

8. Kuo YC, Tsai WJ, Meng HC, Chen WP, Yang YL, Lin CY 2001 Immune responses in human mesangial cells regulated by emodin from Polygonum hypoleucum Ohwi. Life Sci 68:1271-1286. (Sci)

9. Lin CY, Hsieh CC, Chen WP, Yang LY, Wang HH 2001 The underlying diseases and follow-up in Taiwanese children screened by urinalysis. Pediatr Nephrol 16:232-237. (Sci)

10. Hsieh HG, Loong CC, Lui WY, Chen A, Lin CY 2001 IL-17 expression as a possible predictive parameter for subclinical renal allograft rejeciton. Transplant Int 14:287-298. (Sci)

11. Lin CY, Ho CH, Hsieh YH, Kikuchi T 2002 Adeno-associated virus-mediated transfer of human acid maltase gene transient reduction of glycogen accumulation in muscle of Japanese quail with acid maltase deficiency. Gene Therapy 9:554-563. (Sci)

12. Chen CH, Chen WY, Liu HL, Liu TT, Tsou AP, Lin CY, Chao T, Qi Y, Hsiao KJ 2002 Identification of mutations in arginine vasopressin receptor type 2 gene causing nephrogenic diabetes insipidus in chinese patients. J Hum Genet 47:66-73. (Sci)

13. Lin CC, Lin CY, Liaw SF, Chen A 2002 Pulmonary function changes and immunomodulation of Th2 cytokine expression induced by aminophylline after sensitization and allergen challenge in brown norway rats. Ann Allerg Asthma Im 88:215-222. (Sci)

14. Loong CC, Hsieh HG, Lui WY, Chen A, Lin CY 2002 Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejeciton. J Pathol 197:1-12. (Sci)

15. Ko WJ, Lin CY, Chen RJ, Wang SS, Lin FY, Chen YS 2002 Extracorporeal membrane oxigenation support for adult postcardiotoomy cardiogenic shock. Ann Thorac Surg 73:538-545. (Sci)

16. Niu DM, Pan CC, Lin CY, Hwang B, Chung MY 2002 Mosaic or chimera? Revisiting an old hypothesis about the cause of the 46,XX/46,XY hermaphrodite. J Pediatr 140:732-735. (Sci)

17. Niu DM, Hwang B, Chu YK, Liao CJ, Wang PL, Lin CY 2002 High prevalence of a novel mutation (2268 insT) of the thyroid peroxidase gene in Taiwanese patients with total iodide organification defect, and evidence for a founder effect. J Clin Endocr Metab 87:4208-4212. (Sci)

18. Hsieh HG, Loong CC, Lin CY 2002 Interleukin-17 induces src/MAPK cascades activation in human renal epithelial cells. Cytokine 19:159-174. (Sci)

19. Lin CC, Lin CY, Liaw SF, Chen A 2002 Pulmonary function changes and immunodulation of cytokine expression by zafirlukast after sensitization and allergen challenge in brown Norway rats. Clin Exp Allergy 32:960-966. (Sci)

20. Lin CC, Chang CF, Liaw SF, Lin CY 2002 Maximal forced expiratory maneuver to measure airway obstruction in allergen challenged mice. Resp Physiol Neurobi 130:79-87. (Sci)

21. Yang LY, Huang JW, Hsieh HG, Lin CY 2003 H1-A exptracted from Cordyceps sinensis suppresses the proliferation of human mesangial cells and promotes apoptosis, probably by inhibiting the tyrosine phosphorylation of Bcl-2 and Bcl-XL. J Lab Clin Med 141:74-83. (Sci)

22. Wang HH, Lin CY, Huang TP 2003 Patterns of CD4/CD8 T cell ratio in dialysis effluent predict the long-term outcome of peritonitis in peritoneally dialyzed patients. Nephrol Dial Transpl 18:1181-1189. (Sci)

23. Lu IL, Lin CY, Lin SB, Chen ST, Yeh LY, Yang FY, Au LC 2003 Correction/mutation of acid \-D-glucosidase gene by modified single-stranded oligonucleotides: in vitro and in vivo studies. Gene Therapy 10:1910-1916. (Sci)

24. Chang JW, Lin CY 2003 Long-term outcome of heavy proteinuria in patients under 2 years of age. Pediatr Nephrol 18:1044-1048. (Sci)

25. Liu KP, Lin CY, Chen HJ, Wei CF, Lee-Chen GJ 2004 Renin-angiotensin system polymorphisms in Taiwanese primary vesicoureteral reflux. Ped Nephrol 19:594-601. (Sci)

26. Lee CS, Tsai LC, Chao PL, Lin CY, Hung MW, Chient AI, Chiang YT, Han SH 2004 Protein sequence analysis of a novel 103-kDa Dermatophagoides pteronyssinus mite allergen and prevalence of serum immunoglobulin E reactivity to rDer p11 in allergic adult patients. Clin Exp Allergy 34:354-362. (Sci)

27. Lee-Chen GJ, Liu KP, Lai YC, Juang HS, Huang SY, Lin CY 2004 Significance of the tissue kallikrein promoter and transforming growth factor- 1 polymorphisms with renal progression in children with vesicoureteral reflux. Kidney Int 65:4 (April). (Sci)

28. Jackola DR, Liebeler CL, Lin CY*, Chia YK, Blumenthal MN, Rosenberg A 2005 Evidence That Negative Feedback Between Antibody Concentration And Affinity Regulates Humoral Response Consolidation To A Non-Infectious Antigen In Infants. Molecular Immunology 42 (1): 19-30.

29. Fang HYa, Lin CYb , Ko WJc 2005 Hematology and coagulation parameters predic outcom in Taiwanese patients with spontaneous intracerebral hemorrhage. European Journal of Neurology 12:226-232

30. Niu DM, Lin CY, Hwang B, Jap TS, Liao CJ, Wu JY 2005 Contribution of Genetic Factors in Neonatal Transient Hypothroidism. Arch Dis Child 90: 69-72 (Sci)

31. Wang HH, Lin CY 2005 IL-12 and IL-18 Levels in Peritoneal Dialysate Effluent Correlate With the Outcome of Peritonitis in Patients Undergoing Peritoneal Dialysis: Implications for the Type I/Type II T Cell Immune Response. American Journal of Kidney Diseases (Accepted)

32. Chang CC, HUNG CH, YEN CS, HWANG KL, LIN CY. 2005 Ghrelin Has an Important Role in Long-Term Energy Homeostasis Regulation and Left Ventricular Function, but Not as Short-Term Signals to Regulate Feeding in Non-diabetic Hemodialysis Patients. Nephrology Dialysis Transplantation (Accepted)

33. WU HP, LIN CY , CHANG CF, CHANG YJ, Huang CY. 2005 Predictive Value of C-reactive protein at different Cutoff Levels in Acute Appendicitis. American Journal of Emergency Medicine 23:449-453

34. Lee NC, Niu SM, Lin CY, Hsiao KJ, Yang AH, Ng YY. 2005 Galactosidase activity should be examined in patients with proteinuria: what have we learned from a family affected with Fabry disease. Nephrology Dialysis Transplantation. October (2005).

Members of Laboratory