王 學 偉 助理教授

Dr. Hsei-Wei Wang, Assistant Professor

Phone: 886-2-2826-7109
E-mail: hwwang@ym.edu.tw
Education Research Publications


Education

1991, B.S.  台北醫學大學醫事技術系

1992, M.S.  台大醫學院微生物及免疫學所

1998, Ph.D. 台大醫學院微生物所

2003, M.S.  (Bioinformatics)
       Department of Crystallography, Birkbeck College, University of London, UK

1998 - 1998 中央研究院生物醫學所  博士後研究員

1998 - 2000 三峽國防醫學院預防醫學研究所 Military Research Service

2000 - 2004 Post-Doc Research Fellow
       University College London, London, UK

2004-    陽明大學微生物免疫所 助理教授


Research

1. Viral Oncology (KSHV & Kaposi sarcoma; Lentivirus-based gene transfer/targeting)

2.
Bioinformatics (Microarray & related statistics; Protein Modeling; Database construction) Selective recent work: ArrayFusion Web Tool (http://www.ym.edu.tw/microarray/tool"http://www.ym.edu.tw/microarray/tool)

3.Cell Biology (Stem cells; Lymphatic and blood vessel endothelial cells; Apoptosis)


Publications

1. Wang HW, Trotter MW, Lagos D, Bourboulia D, Henderson S, Makinen T, Elliman S, Flanagan AM, Alitalo K, Boshoff C. (2004) Epub 2004 Jun 27. Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat Genet. 2004 Jul;36(7):687-93. (Link)

2. Wang HW, Sharp TV, Koumi A, Koentges G and Boshoff C. (2002) Characterization of an Antiapoptotic Glycoprotein Encoded by Kaposi’s Sarcoma-Associated Herpesvirus Which Resembles a Spliced Variant of Human Survivin. EMBO J. 21(11): 2602-2615. (Link)

3. Sharp TV, Wang HW, Koumi A, Hollyman D, Endo Y, Ye H, Du MQ, Boshoff C. (2002) K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function. J. Virol. 76(2):802-16. (Link)

4. Wang HW, Wu HL, Chen DS, and Chen PJ. (1997) Identification of the functional regions required for hepatitis D virus replication and transcription by linker-scanning mutagenesis of viral genome. Virology 239(1):119-31. (Link)

5. Chia JS, Wu HL, Wang HW, Chen DS, and Chen PJ. (1997) Inhibition of Hepatitis Delta Virus Genomic Ribozyme Self-Cleavage by Aminoglycosides. J. Biomed. Sci. 4:208-216. (Link)

6. Wang HW, Chen PJ, Lee CZ, Wu HL, Chen DS. Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens. J Virol. 1994 Oct;68(10):6363-71. (Link)

 

7. Tsun-Po Yang, Ting-Yu Chang, Chi-Hung Lin, Ming-Ta Hsu and Hsei-Wei Wang* (2006) (*: Corresponding author) ArrayFusion: a web application for the integration of CGH, SNP and microarray data. Bioinformatics (submitted)

 

8. You, RI, Chen, MC, Wang, HW, and Hsieh, SL* (2006) Inhibition of Lymphotoxin-beta Receptor (LTbR)-mediated Cell Death by Survivin-DEx3Cancer Research 66(6):3051-3061. (Link)

 

9. Wang HW* and Boshoff C*. (2005) (*: Corresponding authors) Linking Kaposi virus to cancer-associated cytokines. Trends in Molecular Medicine 11(7):309-312. (Link)



GenBank Sequences Submissions

1. AF229031 (Apr 2000)
  Listeria monocytogenes RecA (recA) gene, complete cds

2. AF228345 (Mar 2000)
  Listeria monocytogenes unknown gene

3. AF242890 (Aug 2000)
  Sagiyama virus envelope glycoprotein E1 gene, partial cds


Selected websites and journals discussed and commented on our research

Nature Reviews Cancer 2004, 4: 572 (Link)

The Lancet, 2004, 364:740-741 (Link)

UCLNews, Wed 14, July 2004 (Link)

http://news.bbc.co.uk/2/hi/health/3860167.stm

http://www.cancerpage.com/news/article.asp?id=7235

http://www.cancerresearchuk.org/news/pressreleases/cancertherapy_27jun04

http://www.news-medical.net/print_article.asp?id=2849

http://www.aidsmeds.com/news/20040628scie005.html

http://www.vidyya.com/vidyyav6i186.htm


Members of Laboratory

Post-doctoral Research Fellow:

張瑞瑾 (Supported by 國科會)

 

PhD Students:

蔡元皓 (博四)

吳佑軒 (博一)

 

MSc Students:

徐竹君 (碩二)

吳旻芬 (碩一)

黃則舜 (碩一)

蘇琡涵

 

Research Technicians:

楊淳博 (George)

林銘裕

蔡淑如