Latest Publications
Biological and Medical Sciences

1 Y.-Q. Chen, P.-l. Chou, C.-Y. Cheng, C.-C. Chiang, M.-T. Wei, C.-T. Chuang, Y.-L. S. Chen, and A. Chiou, “Microrheology of human synovial fluid of arthritis patients studied by diffusing wave spectroscopy,” J. Biophoton., in press (2012).
2. W.-C. Kuo, Y.-S. Lai, C.-M. Lai, and Y.-S. Huang, “Balanced-detection spectral domain OCT with a multi-line single camera for SNR enhancement,” Appl. Opt., in press (2012).
3. K.-L. Lee, P.-W. Chen, S.-H. Wu, J.-B. Huang, S.-Y. Yang, and P.-K. Wei, “Enhancing surface plasmon detection using template-stripped gold nanoslit arrays on plastic films,” ACS Nano 6, 2931 (2012).
4. J.-L. Xiao, H.-J. Pan, and C.-H. Lee, “Optically micropatterned culture of adherent cells,” J. Biomed. Opt. 17, 075004 (2012).
5. T. Buryakina, P.-T. Su, W. J. Syu, C. A. Chang, H.-F. Fan, and F.-J. Kao, “Metabolism of hela cells revealed through autofluorescence lifetime upon infection with enterohemorrhagic Escherichia Coli,” J. Biomed. Opt. 17, 101503 (2012).
6. T. Dellwig, P.-Y. Lin, and F.-J. Kao, “Long-distance fluorescence lifetime imaging using stimulated emission,” J. Biomed. Opt. 17, 011009 (2012).
7. P.-Y. Lin, S.-S. Lee, C.-S. Chang, and F.-J. Kao, “Long working distance fluorescence lifetime imaging with stimulated emission and electronic time delay,” Opt. Express 20, 11445 (2012).
8. N. Mazumder, J. Qiu, M. R. Foreman, C. M. Romero, C.-W. Hu, H.-R. Tsai, P. Tӧrӧk, and F.-J. Kao, “Polarization-resolved second harmonic generation microscopy with a four-channel Stokes-polarimeter,” Opt. Express 20, 14090 (2012).
9. C.-T. Li, H.-F. Chen, I.-W. Un, H.-C. Lee, and T.-J. Yen, “Study of optical phase transduction on localized surface plasmon resonance for ultrasensitive detection,” Opt. Express 20, 3250 (2012).
10. R. S. Moirangthem, M. T. Yaseen, P.-K. Wei, J.-Y. Cheng, and Y.-C. Chang, “Enhanced localized plasmonic detections using partially-embedded gold nanoparticles and ellipsometric measurements,” Biomed. Opt. Express 3, 899 (2012).
11. Y.-C. Kuo, J. H. Ho, T.-J. Yen, H.-F. Chen, and O. K. Lee, “Development of a surface plasmon resonance biosensor for real-time detection of osteogenic differentiation in live mesenchymal stem cells,” PloS One 6, e22382 (2011).
12. O.-H. Tung, S.-Y. Lee, Y.-L. Lai, and H.-F. Chen, “Characteristics of subgingival calculus detection by multi-photon fluorescence microscopy,” J. Biomed. Opt. 16, 066017 (2011).
13. C.-H. Chien, W.-W. Chen, J.-T. Wu, and T.-C. Chang, “Label-free imaging of Drosophila in vivo by coherent anti-Stokes Raman scattering (CARS) and two-photon excitation (TPE) microscopy,” J. Biomed Opt. 16, 016012 (2011).
14. H.-Y. Hsieh, J.-L. Xiao, C.-H. Lee, T.-W. Huang, C.-S. Yang, P.-C. Wang, and F.-G. Tseng, “Au-coated polystyrene nanoparticles with HAR nanocorrugations via surface carboxylation shielded anisotropic etching for significant SERS signal enhancement,” J. Phys. Chem. C 115, 16258 (2011).
15. P.-Y. Lin, H.-C. Lyu, C.-Y. S. Hsu, C.-S. Chang, and F.-J. Kao, “Imaging carious dental tissues with multiphoton fluorescence lifetime imaging microscopy,” Biomed. Opt. Express 2, 149 (2011).
16. C.-P. Chen, A. Ganguly, C.-Y. Lu, T.-Y. Chen, C.-C. Kuo, R.-S. Chen, W.-H. Tu, W. B. Fischer, K.-H. Chen, and L.-C. Chen, “Ultra-sensitive in situ label-free DNA detection using GaN nanowires-based extended-gate field-effect-transistor sensor,” Anal. Chem. 83, 1938 (2011).
17. K.-L. Lee, S.-H. Wu, C.-W. Lee, and P.-K. Wei, “Sensitive biosensors using Fano resonance in single gold nanoslit with periodic grooves,” Opt. Express 19, 24530 (2011).
18. C.-C. Chiang, M.-T. Wei, Y.-Q. Chen, P.-W. Yen, Y.-C. Huang, J.-Y. Chen, O. Lavastre, H. Guillaume, D. Guillaume, and A. Chiou, “Optical tweezers based active microrheology of sodium polystyrene sulfonate (NaPSS),” Opt. Express 19, 8847 (2011).
19. R. S. Moirangthem, Y.-C. Chang, and P.-K. Wei, “Investigation of surface plasmon biosensing using gold nanoparticles enhanced ellipsometry,” Opt. Lett. 36, 775 (2011).
Biological and Medical Sciences
1. S.-W. Kuo, H.-I. Lin, J.-H. Ho, Y.-R. Shih, H.-F. Chen, T.-J. Yen, and O. K. Lee, “Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires,” Biomaterials 33, 5013 (2012).
2. C.-C. Chang, M.-C. Hsieh, J.-C. Lin, and T.-C. Chang, “Selective photodynamic therapy based on aggregation-induced emission enhancement of fluorescent organic nanoparticles,” Biomaterials 33, 897 (2012).
3. K. Wang, W. Lu, J. Chen, S. Xie, H. Shi, H. Hsu, W. Yu, K. Xu, C. Bian, W. B. Fischer, W. Schwarz, L. Feng, and B. Sun, ”PEDV ORF3 encodes an ion channel protein and regulates virus production,” FEBS Lett. 586, 384 (2012).
4. S.-P. Lin, S. Mandell, Y. Chang, P.-T. Chen, M.-Y. Tsou, K.-H. Chan, and C.-K. Ting, “Discriminant analysis for anaesthetic decision making: an intelligent recognition system for epidural needle insertion,” Brit. J. Anesthesia 108, 302 (2012).
5. T.-H. Hsu, Y.-L. Kao, W.-L. Lin, J.-L. Xiao, P.-L. Kuo, C.-W. Wu, W.-Y. Liao, and C.-H. Lee, “The migration speed of cancer cells influenced by macrophages and myofibroblasts co-cultured in a microfluidic chip,” Integr. Biol. 4, 177 (2012).
6. Y.-C. Lee, Y.-C. Yang, C.-L. Huang, J.-H. Lin, D.-M. Yang, and N.-K. Huang, “When cytokinin, a plant hormone, meets the adenosine A2A receptor: a novel neuroprotectant and lead for treating neurodegenerative disorders?” PloS One 7, e38865 (2012).
7. T.-Y. Chuang, L.-C. Au, L.-C. Wang, L.-T. Ho, D.-M. Yang, and C.-C. Juan, “Potential effect of resistin on the ET-1-increased reactions of blood pressure in rats and Ca2+ signaling in vascular smooth muscle cells,” J. Cell. Physiol. 227, 1610 (2012).
8. G.-S. Hong, C.-P. Chen, M.-H. Lin, J. Krüger, C. F. W. Becker, R. H. A. Fink, and W. B. Fischer, “Molecular dynamics simulations and conductance studies of the interaction of VP1 from Polio virus and gp41 fusion peptide from HIV-1 with lipid membranes,” Mol. Membr. Biol. 29, 9 (2012).
9. T.-H. Huang, S.-J. Chiu, P.-H. Chiang, W.-T. Li, S.-H. Chiou, C.-T. Chen, C. A. Chang, J.-C. Chen, and Y.-J. Lee, “Liferative effects of n-heterocyclic indolyl glyoxylamidederivatives on human lung cancer cells,” Anticancer Res. 31, 3407 (2011).
10. Y.-B. Kuo, C.-W. Fan, C. A. Chang, C.-C. Chan, R.-P. Hung, Y.-S. Hung, K.-T. Chen, J.-S. Yu, Y.-S. Chang, and E.-C. Chan, “Identification of phospholipid Scramblase 1 as a serological marker and its prognostic value for colorectal cancer,” Mol. Medicine 17, 41 (2011).
11. K.-D. Chen, P.-T. Chang, Y.-H. Ping, H.-C. Lee, C.-W. Yeh, P.-N. Wang, “Gene expression profiling of peripheral blood leukocytes identifies and validates ABCB1 as a novel biomarker for Alzheimer's disease,” Neurobiol. Disease 43, 698 (2011).
12. C.-W. Huang, H.-Y. Chen, M.-H. Yen, J. J. W. Chen, T.-H. Young, and J.-Y. Cheng, “Gene expression of human lung cancer cell line CL1-5 in response to a direct current electric field,” PLoS One 6, e25928 (2011).
13. T.-H. Hsu, J.-L. Xiao, Y.-W. Tsao, Y.-L. Kao, S.-H. Huang, W.-Y. Liao, and C.-H. Lee, “Analysis of the paracrine loop between cancer cells and fibroblasts using a microfluidic chip,” Lab Chip 11, 1808 (2011).
14. Y.-L. Yu, R.-H. Chou, L.-T. Chen, W.-C. Shyu, S.-C. Hsieh, C.-S. Wu, H.-J. Zeng, S.-P. Yeh, D.-M. Yang, S.-C. Hung, and M.-C. Hung, “EZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling,” J. Biol. Chem. 286, 9657 (2011).
15. M. Skasko, A. Tokarev, C.-C. Chen, W. B. Fischer, S. K. Pillai, J. Guatelli, “BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action,” Virology 411, 65 (2011).
16. W. B. Fischer and H.-J. Hsu, “Viral channel forming proteins–modelling the target,” Biochim. Biophys. Acta 1808, 561 (2011).
1. Y.-S. Sun, S.-W. Peng, K.-H. Lin, and J.-Y. Cheng, “Electrotaxis of lung cancer cells in ordered three-dimensional scaffolds,” Biomicrofluidics 6, 014102 (2012).
2. C.-C. Wang, Y.-C. Kao, P.-Y. Chi, C.-W. Huang, J.-Y. Lin, C.-F. Chou, J.-Y. Cheng, and C.-H. Lee, “Asymmetric cancer-cell filopodium growth induced by electric-fields in a microfluidic culture chip,” Lab Chip 11, 695 (2011).