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Jens
Krüger
 send email
phone: +886-2-2826-5674
Research Interest
Cutting edge simulation techniques used to simulate membrane bound
proteins like channel forming viral
proteins (M2 - Influenza, Vpu - HIV-1, 3a - SARS). Special emphasis
lies in the specifc characteristics of the lipid
enviroment. All kind of techniques from quantum calculation to coarse
grained MD are employed to get grip on processes like
protein assembly, membrane dynamics, ion and drug permeation through
channels and dynamic ligand/receptor interactions.
|
2009 |
Relocation to the University of Paderborn, Germany with a research fellowship of the
Alexander von Humboldt-Foundation
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|
2008 |
Research fellowship of the
Alexander von Humboldt-Foundation and the National Science Council
Taiwan
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|
2007 |
Postdoctoral Fellow,
Institute of Biophotonics, National Yang-Ming University, Taiwan
(R.O.C),
W. B. Fischer
|
| 2006 |
Ph.D.-Thesis, Dept. of
Organic Chemistry, University of Paderborn, Germany,
G. Fels
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Publications
| 11.) |
J. Krüger and W. B.
Fischer;
Mutants of Vpu1-32 from HIV-1.
(submitted) |
| 10.) |
J. Krüger and W. B.
Fischer;
Assembly of viral Membrane Proteins.
(submitted) |
| 9.) |
J. Krüger and W. B.
Fischer;
Viral channel forming proteins
International Review in Cytology (in print) |
| 8.) |
J. Krüger and W. B.
Fischer;
Exploring the Conformational Space of Vpu from
HIV-1: a versatile adaptable protein
Journal of Computational Chemistry 28(14):2416-2424, 2008. |
| 7.) |
G. Patargias, H.
Martay, J. Krüger, C.-P. Chen, Y.-T. Wang, M.-D. Lee, C.-C. Chen, G.-S.
Hong, W. B. Fischer;
Short Membrane Proteins from Viruses: channel-pore
dualism?
From Computational Biophysics to Systems Biology (CBSB08), Proceedings,
U. H. E. Hansmann, J. Meinke, S. Mohanty, O. Zimmermann (Hrsg.),
ISBN-987-3-9810843-6-8, (2008). |
| 6.) |
J. Krüger, W. B.
Fischer;
Viral membrane proteins: Flexibility and Assembly
From Computational Biophysics to Systems Biology (CBSB08), Proceedings,
U. H. E. Hansmann, J. Meinke, S. Mohanty, O. Zimmermann (Hrsg.),
ISBN-987-3-9810843-6-8, (2008) |
| 5.) |
J. Krüger, G.
Patargias, H. Martay, T. Mehnert, A. Routh, P. J. Judge, Y. H. Lam, D.
Fischer, A. Watts, W. B. Fischer;
Self- Assembly of Viral Ion Channel Forming
Proteins
Proceedings of the IX. Linz Winter Workshop 2007, (2008) 31-35,
TRAUNER Druck, Linz, AT ISBN 978-3-85499-400-8 |
| 4.) |
T. Witte, L. A. Haller,
E. Luttmann, J. Krüger, G. Fels and K. Huber;
Time Resolved Structure Analysis of Growing
β-Amyloid Fibers
Journal of Structural Biology 159(1):71-81, 2007. |
| 3.) |
J. Krüger, B. Manmontri
and G. Fels;
Iridium catalyzed H/D-exchange
European Journal of Organic Chemistry 7:1402-1408, 2005. |
| 2.) |
J. Krüger, B. Manmontri
and G. Fels;
H/D-Exchange in aromatic systems using transition
metal catalysis
Journal of labelled Compounds and Radiopharmaceuticals 47:1050, 2004. |
| 1.) |
J. Krüger and G. Fels;
(-)-[3H]-Galanthamine -
Application as Photoaffinity Probe
Journal of labelled Compounds and Radiopharmaceuticals 47:258-260,
2003. |
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