專任教師

林滿玉教授
Lin, Anya Maan-Yuh
藥學系|主任 2016年迄今
(02)28267000#7983
(02)28712121#2688
myalin@ym.edu.tw
myalin@vghtpe.gov.tw
美國科羅拉多州州立大學|藥理學博士1989-1992
中華民國國立臺灣大學|藥理學碩士1982-1984
中華民國國立臺灣大學|藥學士 1978-1982
  • 專長
    神經藥理、神經再生、轉譯醫學研究
  • 現職
    • 國立陽明大學|藥學系|主任2016年迄今
    • 國立陽明大學|藥理學研究所|專任教授 2008年8月迄今
    • 臺北市石牌榮民總醫院|教學研究部|合聘研究員 2005年8月迄今
  • 經歷
    • 國立陽明大學|藥學系籌備處|主任2015年8月至2016年7月
    • 國立陽明大學|藥理學研究所|所長2008年8月至2014年
    • 國立陽明大學|生理學研究所|專任教授 2005年8月至2008年7月
    • 臺北市石牌榮民總醫院|教學研究部|專任研究員 2004年至2005年7月
    • 國立陽明大學|生理學研究所|兼任副教授 1998年至2005年2月
    • 臺北市石牌榮民總醫院|教學研究部|專任副研究員 1996年至2004年
    • 中央研究院|生物醫學科學研究所|博士後研究員 1993年10月至1996年10月
    • 美國國家衛生研究院|客座博士後研究員 1992年8月至1993年9月
  • 論文
    1. Teng YC, Jeng CJ, Huang HJ, Lin AMY*. Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein. Toxicol Lett. 2015 Mar 18;233(3):239-45.
    2. Tang MC, Wu MY, Hwang MH, Chang YT, Huang HJ, Lin AMY*, Yang JCH. Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells. PLoS One. 2015 Mar 25; 10(3):e0119135.
    3. Teng YC, Tai YI, Huang HJ, Lin AMY.* Melatonin ameliorates arsenite-induced neurotoxicity: involvement of autophagy and mitochondria. Mol Neurobiol. 2015 Oct;52(2):1015-22
    4. Hung KC, Huang HJ, Lin MW, Lei YP, Lin AMY.* Roles of autophagy in MPP+-induced neurotoxicity in vivo: the involvement of mitochondria and α-synuclein aggregation. PLoS One. 2014 Mar 19;9(3):e91074.
    5. Teng YC, Tai YI, Lee YH, Lin AMY.* Role of HO-1 in the arsenite-induced neurotoxicity in primary cultured cortical neurons. Mol Neurobiol. 2013 Oct;48(2):281-7.
    6. Huang MH, Lee JH, Chang YJ, Tsai HH, Lin YL, Lin AMY,* Yang JC.MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. Mol Oncol. 2013 Feb;7(1):112-20.
    7. Lee YC, Lee LM, Yang CH, Lin AMY*, Huang YC, Hsu CC, Chen MS, Chi CW, Yin PH, Kuo CD, Liao JF, Lee HC. Norcantharidin suppresses cell growth and migration with enhanced anticancer activity of gefitinib and cisplatin in human non-small cell lung cancer cells. Oncol Rep. 2013 Jan;29(1):237-43.
    8. Chang CF, Huang HJ, Lee HC, Hung KC, Wu RT, Lin AMY*. Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation.J Pineal Res. 2012 Apr;52(3):312-21.
    9. Lin AMY*, Wu LY, Hung KC, Huang HJ, Lei YP, Lu WC, Hwang LS. Neuroprotective effects of longan (Dimocarpus longan Lour.) flower water extract on MPP+-induced neurotoxicity in rat brain. J Agric Food Chem. 2012 Sep 12;60(36):9188-94.
    10. Lin AMY*, Ping YH, Chang GF, Wang JY, Chiu JH, Kuo CD, Chi CW. Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain. J Ethnopharmacol. 2011 Apr 12;134(3):884-91.
    11. Lin A.M.Y., Feng S.F., Chao P.L., Yang C.H. Melatonin inhibits arsenite-induced peripheral neurotoxicity. J. Pineal. Res. 46: 64-70(2009)
    12. Fan S.F., Chao P.L., Lin A.M.Y. Arsenite induces oxidative injury in rat brain: Synergistic effect of iron. Ann. N. Y. Acad. Sci. (in press)
    13. Chao YH, P.L. Chao, Tsai MJ, Cheng HH., CGen KB., Yang DM., C.H. Yang, Lin A.M.Y. Arsenite-induced cytotoxicity in DRG explants. Free. Radic. Biol. Med. 44: 1553-1561 (2008)
    14. Lin A.M.Y. Fang S.F., Chao P.L., Yang C.H. Melatonin attenuates arsenite-induced apoptosis in rat brain: Involvement of mitochondrial and ER pathways and aggregation of a-synuclein. J. Pineal. Res. 43(2): 163-171 (2007)
    15. Lin A.M.Y., Chao P.L., Fang S.F., Chi C.W., Yang C.H. Endoplasmic reticulum stress is involved in arsenite-induced oxidative injury in rat brain. Toxicol. Appl Pharmacol. 224: 138-146 (2007)
    16. Chao P.L., Fan S.F., Chou Y.H., Lin A.M.Y. N-acetylcysteine attenuates arsenite-induced oxidative injury in DRG explants. Ann. N.Y. Acad. Sci. 1122: 276-288. (2007)
康照洲教授
Kang, Jaw-Jou
藥物科學院院長 2016年迄今
02-28267000 #7300
Office:行政大樓301室
美國加州大學聖地牙哥分校|化學博士1983-1989
中華民國國立臺灣大學|藥學學士1975-1979
  • 專長
    毒性測試、藥物管理及安全、食品管理及安全、安全性(風險)評估
  • 現職
    • 國立陽明大學藥物科學院院長
    • 國立臺灣大學毒理學研究所教授
    • 中華民國毒物學會理事長
  • 經歷
    • 行政院食品安全辦公室主任2015年2月至2016年9月
    • 行政院衛生署食品藥物管理局局長2010年1月至2013年7月
    • 行政院衛生署藥物食品檢驗局局長2009年10月至2009年12月
    • 行政院衛生署藥政處處長 2009年8月至2009年12月
    • 國立台灣大學醫學院藥物研究中心主任 2007年8月至2009年7月
    • 國立台灣大學毒理學研究所副教授 1991年8月至1998年7月
    • 波士頓生物醫學研究所博士後研究 1989年6月至1991年7月
  • 論文
    1. Motorcycle exhaust particles up-regulate expression of vascular adhesion molecule-1 and intercellular adhesion molecule-1 in human umbilical vein endothelial cells. Lee, .CC., Huang, S.H., Yang, Y.T., Cheng, Y.W., Li, C.H. and Kang, J.J.* Toxicology in vitro (26):552-560, 2012.
    2. Organ biodistribution, clearance, and genotoxicity of orally administered zinc oxide nanoparticles in mice. Li, C.H., She, C.C., Cheng, Y.W., Huang, S.H., Wu, C.C., Kao, C.C., Liao, J.W. and Kang, J.J.* Nanotoxicology (6):746-756, 2012
    3. Zinc oxide nanoparticles induced intercellular adhesion molecule 1 expression requires Rac1/Cdc42, mixed-lineage kinase 3, and c-Jun N-terminal kinase activation in endothelial cells. Li, C.H., Liao, P.L., Shyu, M.K., Liu, C.W., Kao, C.C., Huang, S.H., Cheng, Y.W. and Kang, J.J.* Toxicological Sciences (126):162-172, 2012.
    4. Crisis management turns Taiwan's plasticizer nightmare into progressive policy. Kang, J.J., Chu, S.F., Wu, Z.Z., Chou, S.W., Tsai, S.J. and Chiu, W.T. J Formos Med Assoc. 111(8):409-11, 2012.
    5. Antiallergic asthma properties of brazilin through inhibition of TH2 responses in T cells and in a murine model of asthma. Lee, C.C., Wang, C.N., Kang, J.J., Liao, J.W., Chiang, B.L., Chen, H.C., Hu, C.M., Lin, C.D., Huang, S.H., and Lai Y.T. J Agric Food Chem. 19;60(37):9405-14, 2012.
    6. Metabolism of (2S)-pterosin A: identification of the phase I and phase II metabolites in rat urine. Lee, Y.P., Hsu, F.L., Kang, J.J., Chen, C.K. and Lee, S.S. Drug Metab Dispos. 40 (8):1566-74, Aug, 2012.
    7. Metabolomic analysis of complex chinese remedies: examples of induced nephrotoxicity in the mouse from a series of remedies containing aristolochic Acid. Tsai DM, Kang JJ, Lee SS, Wang SY, Tsai IL, Chen GY, Liao HW, Wei-Chu L, Kuo CH, Tseng YJ., Evid Based Complement Alternat Med. , 2013:263757
    8. Evaluation of acute, 13-week subchronic toxicity and genotoxicity of the powdered root of Tongkat Ali (Eurycoma longifolia Jack). Li, C.H., Liao, J.W., Liao, P.L., Huang, W.K., Tse, L.S., Lin, C.H., Kang, J.J.* and Cheng, Y.W.* Evidence-Based Complementary and Alternative Medicine., 2013
    9. Minocycline accelerates hypoxia-inducible factor-1 alpha degradation and inhibits. Li, C.H., Liao, P.L., Yang, Y.T., Huang, S.H., Lin, C.H., Cheng, Y.W. and Kang, J.J.* Archives of Toxicology, 88(3):659-671, 2014
    10. Metabolites of antroquinonol found in rat urine following oral administration, Chien-Kuang Chen, Jaw-Jou Kang, Wu-Che Wen, Hui-Fen Chiang, and Shoei-Sheng Lee, Journal of Natural Products, 25;77(4):1061-4, 2014.
    11. Snail regulates Nanog status during the epithelial-mesenchymal transition via the Smad1/Akt/GSK3β signaling pathway in non-small-cell lung cancer. Liu CW, Li CH, Peng YJ, Cheng YW, Chen HW, Liao PL, Kang JJ*, Yeng MH*., Oncotarget, 5(11): 3880–3894, 2014.
    12. Zinc oxide nanoparticles impair bacterial clearance by macrophages., Lin CD, Kou YY, Liao CY, Li CH, Huang SP, Cheng YW, Liao WC, Chen HX, Wu PL, Kang JJ, Lee CC, Lai CH., Nanomedicine (Lond), 9(9):1327-39, 2014.
    13. The evolution and challenges for the international harmonization of the regulation of pharmaceutical excipients in Taiwan. Lin-Chau Chang, Jaw-Jou Kang, Churn-Shiouh Gau, Regulatory Toxicology and Pharmacology, 73, 947-952, 2015.
    14. Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability in mice, Li CH, Shyu MK, Jhan C, Cheng YW, Tsai CH, Liu CW, Lee CC, Chen RM, Kang JJ*. Toxicological Sciences, 148(1):192-203, 2015.
    15. NcoA2-dependent inhibition of HIF-1α activation is regulated via AhR., Chi-Hao Tsai, Ching-Hao Li, Po-Lin Liao, Yu-Wen Cheng, Cheng-Hui Lin, Shih-Hsuan Huang, and Jaw-Jou Kang*, Toxicological Sciences, 148(2):517-30, 2015.
    16. Development of the risk-based, phased-in approach for the international harmonization of the regulation of container closure systems for drugs in Taiwan., Lin-Chau Chang, Jaw-Jou Kang, Churn-Shiouh Gau, Regulatory Toxicology and Pharmacology, 77:252-256, 2016.
    17. Ligand independent aryl hydrocarbon receptor inhibits lung cancer cell invasion by degradation of Smad4, Chen-Chen Lee, Wen-Hao Yang, Ching-Hao Li, Yu-Wen Cheng, Chi-Hao Tsai, Jaw-Jou Kang*, CANCER LETTERS, 2016 Jul, 376(2):211-217, SCI.
陳日榮 教授
Chen, Jih-Jung
藥學系|教授 2017年2月迄今
02-28267000#7195
高雄醫學大學|藥學研究所|藥學博士1994-1997
高雄醫學大學|天然藥物研究所|理學碩士1992-1994
中國醫藥大學|醫技系|理學士 1985-1989
  • 專長
    生藥學、中藥學、天然物化學、新藥研發
  • 現職
    • 國立陽明大學|藥學系|教授2017年2月迄今
  • 經歷
    • 大仁科技大學 中草藥科技研究中心 主任
    • 大仁科技大學 貴重儀器中心 主任
    • 考試院 公務人員高等考試命題兼閱卷委員
    • 大仁科技大學 兩岸沉香產業發展研究中心 主任
    • 高雄醫學大學 天然藥物研究所校友會 會長
    • 中國高等職業教育國家級培訓講座教師
      American Journal of Applied Chemistry, ISRN Pharmaceutics, Asian Journal of Biomedical and Pharmaceutical Sciences…等13種國際期刊編輯委員
      Food Chem., J. Nat. Prod., Planta Med., J. Agri. Food Chem., Marine Drugs, Brit. J. Pharmacol, Phytochemistry…等48種國際SCI期刊評審委員
  • 論文
    1. Ian-Lih Tsai, Wine-Show Sheen, Jih-Jung Chen, Ih-Sheng Chen. Isolation of constituents from the leaves of Syzygium tripinnatum. The Chinese Pharmaceutical Journal 1994, 46 (5), 401-412. {1994. 10}
    2. Ih-Sheng Chen, Jih-Jung Chen, Ian-Lih Tsai. Alkaloids from Hernandia sonora. Phytochemistry 1995, 40 (3), 983-986. {1995. 10} (SCI, 2013 Impact Factor = 3.350) (Ranking in Plant Sciences: 28/196 = 14.3 %)
    3. Ih-Sheng Chen, Jih-Jung Chen, Ian-Lih Tsai, Ya-Ling Chang, Che-Ming Teng. New p-quinonoid aporphine alkaloids and antiplatelet aggregation constituents of Hernandia sonora. Planta Medica 1995, 61 (6), 537-539. {1995. 12} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 60/196 = 30.6 %)
    4. Jih-Jung Chen, Ian-Lih Tsai, Ih-Sheng Chen. New oxoaporphine alkaloids from Hernandia nymphaeifolia. Journal of Natural Products 1996, 59 (2), 156-158. {1996. 02} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    5. Ih-Sheng Chen, Jih-Jung Chen, Ian-Lih Tsai. N-Formyl- and N-hydroxyaporphine alkaloids from Fomosan Hernandia nymphaeifolia. Heterocycles 1996, 43 (4), 799-807. {1996. 04} (SCI, 2013 IF = 0.908)
    6. Jih-Jung Chen, Ian-Lih Tsai, Tsutomu Ishikawa, Chyi-Jia Wang, Ih-Sheng Chen. Alkaloids from trunk bark of Hernandia nymphaeifolia. Phytochemistry 1996, 42 (5), 1479-1484. {1996. 07} (SCI, 2013 IF = 3.350) (Ranking in Plant Sciences: 28/196 = 14.3 %)
    7. Jih-Jung Chen, Tsutomu Ishikawa, Chang-Yih Duh, Ian-Lih Tsai, Ih-Sheng Chen. New dimeric aporphine alkaloids and cytotoxic constituents of Hernandia nymphaeifolia. Planta Medica 1996, 62 (6), 528-533. {1996. 12} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 60/196 = 30.6 %)
    8. Ih-Sheng Chen, Jih-Jung Chen, Chang-Yih Duh, Ian-Lih Tsai, Chin-Teng Chang. New aporphine alkaloids and cytotoxic constituents of Hernandia nymphaeifolia. Planta Medica 1997, 63 (2), 154-157. {1997. 04} (SCI, 2012 IF = 2.348) (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 60/196 = 30.6 %)
    9. Ih-Sheng Chen, Jih-Jung Chen, Chang-Yih Duh, Ian-Lih Tsai. New cytotoxic lignans from Formosan Hernandia nymphaeifolia. Phytochemistry 1997, 45 (5), 991-996. {1997. 07} (SCI, 2013 IF = 3.350) (Ranking in Plant Sciences: 28/196 = 14.3 %)
    10. Ih-Sheng Chen, Inn-Wha Tsai, Che-Ming Teng, Jih-Jung Chen, Ya-Ling Chang, Feng-Nien Ko, Matthias C. Lu, John M. Pezzuto. Pyranoquinoline alkaloids from Zanthoxylum simulans. Phytochemistry 1997, 46 (3), 525-529. {1997. 10} (SCI, 2013 IF = 3.350) (Ranking in Plant Sciences: 28/196 = 14.3 %)
    11. Jih-Jung Chen, Chang-Yih Duh and Ih-Sheng Chen. New tetrahydroprotoberberine N-oxide alkaloids and cytotoxic constituents of Corydalis tashiroi. Planta Medica 1999, 65 (7), 643-647. {1999. 10} (SCI, 2012 IF = 2.339) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    12. Jih-Jung Chen, Ya-Ling Chang, Che-Ming Teng, Ih-Sheng Chen. Anti-platelet aggregation alkaloids and lignans from Hernandia nymphaeifolia. Planta Medica 2000, 66 (3), 251-256. {2000. 04} (SCI, 2012 IF = 2.339) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    13. Jih-Jung Chen, Ya-Ling Chang, Che-Ming Teng, Wei-Yu Lin, Yu-Chang Chen, Ih-Sheng Chen. A new tetrahydroprotoberberine N-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi. Planta Medica 2001, 67 (5), 423-427. {2001. 07} (SCI, 2012 IF = 2.339) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    14. Jih-Jung Chen, Ya-Ling Chang, Che-Ming Teng, Ih-Sheng Chen. Vasorelaxing and antioxidant constituents from Hernandia nymphaeifolia. Planta Medica 2001, 67 (7), 593-598. {2001. 09} (SCI, 2012 IF = 2.339) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    15. Ih-Sheng Chen, Hui-Fang Chen, Ming-Jen Cheng, Ya-Ling Chang, Che-Ming Teng, Ishikawa Tsutomu, Jih-Jung Chen, Ian-Lih Tsai. Quinoline alkaloid and other constituents of Melicope semecarpifolia with antiplatelet aggregation activity. Journal of Natural Products 2001, 64 (9), 1143-1147. {2001. 09} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    16. Yu-Ying Chao, Warren Su, Chung-Ren Jan, Ying-Chin Ko, Jih-Jung Chen, Jin-Shiung Cheng, Chun-Peng Liu, Yuk-Keung Lo, Yee-Ping Law, Kang-Ju Chou, Kam-Chung Lee, Wei-Chung Chen, Ih-Sheng Chen. Novel action of lignans isolated from Hernandia nymphaeifolia on Ca2+ signaling in human neutrophils. Archives of Toxicology 2002, 75 (11-12), 695-702. {2002. 01} (SCI, 2014 IF = 5.980) (Ranking in Toxicology: 8/83 = 9.6 %)
    17. Yu-Ying Chao, Chung-Ren Jan, Ying-Chin Ko, Jih-Jung Chen, Ih-Sheng Chen. Effect of lignans isolated from Hernandia nymphaeifolia on reactive oxygen species generation and calcium mobilization in human neutrophils. Drug Development Research 2002, 55 (2), 118-126. {2002. 02} (SCI, 2014 IF = 0.869)
    18. Yu-Ying Chao, Chung-Ren Jan, Ying-Chin Ko, Jih-Jung Chen, Bang Ping Jiann, Yih-Chau Lu, Wei-Chung Chen, Warren Su, Ih-Sheng Chen. Effect of lignans isolated from Hernandia nymphaeifolia on estrogenic compounds-induced calcium mobilization in human neutrophils. Life Sciences 2002, 70 (26), 3109-3121. {2002. 05} (SCI, 2014 IF = 2.555) (Ranking in Pharmacology & Pharmacy: 115/249 = 46.1 %)
    19. Yu-Ying Chao, Ih-Sheng Chen, Jwu-Lai Yeh, Jih-Jung Chen, Ying-Chin Ko, Jin-Shiung Cheng, Chun-Peng Liu, Yuk-Keung Lo, Warren Su, Yee-Ping Law, Kang-Ju Chou, Wei-Chung Chen, Chung-Ren Jan. Novel action of lignans isolated from Hernandia nymphaeifolia on Ca2+ signaling in renal tubular cells. European Journal of Pharmacology 2002, 443 (1-3), 31-38. {2002. 05} (SCI, 2014 IF = 2.592) (Ranking in Pharmacology & Pharmacy: 90/249 = 36.1 %)
    20. Jih-Jung Chen, Ya-Ling Chang, Che-Ming Teng, Chao-Chen Su, Ih-Sheng Chen. Quinoline alkaloids and anti-platelet aggregation constituents from the leaves of Melicope semecarpifolia. Planta Medica 2002, 68 (9), 790-793. {2002. 09} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    21. Jih-Jung Chen, Yu-Chun Huang, Yu-Chang Chen, Yao-Ting Huang, Shih-Wei Wang, Chieh-Yu Peng, Che-Ming Teng, Ih-Sheng Chen. Cytotoxic amides from Piper sintenense. Planta Medica 2002, 68 (11), 980-985. {2002. 11} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    22. Jih-Jung Chen*, Chang-Yih Duh, Hung-Yi Huang, Ih-Sheng Chen*. Furoquinoline alkaloids and cytotoxic constituents from the leaves of Melicope semecarpifolia. Planta Medica 2003, 69 (6), 542-546. {2003. 06} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    23. Jih-Jung Chen*, Chang-Yih Duh, Hung-Yi Huang, Ih-Sheng Chen*. Cytotoxic constituents of Piper sintenense. Helvetica Chimica Acta 2003, 86 (6), 2058-2064. {2003, 06} (SCI, 2014 IF = 1.138) (Ranking in Chemistry, Multidisciplinary: 69/152 = 45.3 %)
    24. Ajay Kumar Dixit, Jih-Jung Chen, Tsutomu Ishikawa, Ian-Lih Tsai, Ih-Sheng Chen. Alkyl phenols from the leaves of Formosan Ardisia virens. The Chinese Pharmaceutical Journal 2003, 55 (4), 273-278. {2003. 08}
    25. Fan-Pin Lee, Yu-Cheng Chen, Jih-Jung Chen, Ian-Lih Tsai, Ih-Sheng Chen. Cyclobutanoid amides from Piper arborescens. Helvetica Chimica Acta 2004, 87 (2), 463-468. {2004. 02} (SCI, 2014 IF = 1.138) (Ranking in Chemistry, Multidisciplinary: 69/152 = 45.3 %)
    26. Yu-Chang Chen, Jih-Jung Chen, Ya-Ling Chang, Che-Ming Teng, Wei-Yu Lin, Chin-Chung Wu, Ih-Sheng Chen. A new aristolactam alkaloid and anti-platelet aggregation constituents from Piper taiwanense. Planta Medica 2004, 70 (2), 174-177. {2004. 02} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    27. Jih-Jung Chen*, Hung-Yi Huang, Chang-Yih Duh, Ih-Sheng Chen*. Cytotoxic constituents from the stem bark of Zanthoxylum pistaciiflorum. Journal of the Chinese Chemical Society 2004, 51 (3), 659-663. {2004. 06} (SCI, 2014 IF = 0.648)
    28. Jih-Jung Chen*, Ru-Wei Lin, Chang-Yih Duh, Hung-Yi Huang, Ih-Sheng Chen*. Flavones and cytotoxic constituents from the stem bark of Muntingia calabura. Journal of the Chinese Chemical Society 2004, 51 (3), 665-670. {2004. 06} (SCI, 2014 IF = 0.648)
    29. Jih-Jung Chen*, Ih-Sheng Chen, Chang-Yih Duh. Cytotoxic xanthones and biphenyls from the root of Garcinia linii. Planta Medica 2004, 70 (12), 1195-1200. {2004, 12} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    30. Wen-Yu Lin, Chien-Fang Peng, Ian-Lih Tsai, Jih-Jung Chen, Ming-Jen Cheng, Ih-Sheng Chen. Antitubercular constituents from the root of Engelhardia roxburghiana. Planta Medica 2005, 71 (2), 171-175. {2005. 02} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    31. Jih-Jung Chen*, Chang-Yih Duh, Ih-Sheng Chen*. Cytotoxic chromenes from Myriactis humilis. Planta Medica 2005, 71 (4), 370-372. {2005.04} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    32. Jih-Jung Chen*, Hui-Yu Fang, Chang-Yih Duh, Ih-Sheng Chen*. New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum. Planta Medica 2005, 71 (5), 470-475. {2005.05} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    33. Ian-Lih Tsai, Fan-Pin Lee, Chin-Chung Wu, Chang-Yih Duh, Tsutomu Ishikawa, Jih-Jung Chen, Yu-Chang Chen, Hiroko Seki, Ih-Sheng Chen. New cytotoxic cyclobutanoid amides, a new furanoid aphth and anti-platelet aggregation constituents from Piper arborescens. Planta Medica 2005, 71 (6), 535-542. {2005.06} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    34. Jih-Jung Chen*, Chang-Yih Duh, Jinn-Fen Chen. New Cytotoxic Biflavonoids from Selaginella delicatula. Planta Medica 2005, 71 (7), 659-665. {2005. 07} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    35. Jih-Jung Chen*, Hsinn-Hsing Lee, Chang-Yih Duh, Ih-Sheng Chen*. Cytotoxic chalcones and flavonoids from the leaves of Muntingia calabura. Planta Medica 2005, 71 (10), 970-973. {2005. 09} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    36. Hsueh-Chun Chou, Jih-Jung Chen, Chang-Yih Duh, Tur-Fu Huang, Ih-Sheng Chen. Cytotoxic and anti-platelet aggregation constituents from the root wood of Melicope semecarpifolia. Planta Medica 2005, 71 (11), 1078-1081. {2005. 10} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    37. Feng-Lang Lin, Jih-Jung Chen, Cheng-Dean Shih. Antinociceptive and anti-inflammatory activity of the water-soluble extracts from leaves of Muntingia calabura. The Chinese Pharmaceutical Journal 2005, 57 (2-6), 81-88. {2005. 04-12}
    38. Jih-Jung Chen*, En-Tzu Chou, Chang-Yih Duh, Sheng-Zehn Yang, Ih-Sheng Chen. New cytotoxic tetrahydrofuran- and dihydrofuran-type lignans from the stem of Beilschmiedia tsangii. Planta Medica 2006, 72 (4), 351-357. {2006.02} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    39. Jih-Jung Chen*, Chien-Fang Peng, Hung-Yi Huang, Ih-Sheng Chen. Benzopyrans, biphenyls and xanthones from the root of Garcinia linii and their activity against Mycobacterium tuberculosis. Planta Medica 2006, 72 (5), 473-477. {2006.02} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    40. Jih-Jung Chen*, Tsung-Hsien Chou, Chang-Yih Duh, Ih-Sheng Chen. Cytotoxic dihydroagaro- furanoid sesquiterpenes from the stem of Microtropis fokienensis. Journal of Natural Products 2006, 69 (4), 685-688. {2006.04} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    41. Jih-Jung Chen*, Shi-Yu Huang, Chang-Yih Duh, Ih-Sheng Chen, Tai-Chi Wang, Hui-Yu Fang. A new cytotoxic amide from the stem wood of Hibiscus tiliaceus. Planta Medica 2006, 72 (10), 935-938. {2006.08} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    42. Cheng-Dean Shih*, Jih-Jung Chen, Hsinn-Hsing Lee. Activation of nitric oxide signaling pathway mediates hypotensive effect of Muntingia calabura L. (Tiliaceae) leaf extract. American Journal of Chinese Medicine 2006, 34 (5), 857-872. {2006. 09} (SCI, 2012 Impact Factor = 2.281)
    43. Jih-Jung Chen*, Tsung-Hsien Chou, Chien-Fang Peng, Ih-Sheng Chen, Sheng-Zehn Yang. Antitubercular dihydroagarofuranoid sesquiterpenes from the roots of Microtropis fokienensis. Journal of Natural Products 2007, 70 (2), 202-205. {2007.02} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    44. Ping-Jyun Sung*, Mei-Ru Lin, Jih-Jung Chen, Shen-Fan Lin, Yang-Chang Wu, Tsong-Long Huang, Lee-Shing Fang. Hydroperoxysterols from the tunicate Eudistoma sp. Chemical & Pharmaceutical Bulletin 2007, 55 (4), 666-668. {2007.04} (SCI, 2012 Impact Factor = 1.564) (Ranking in Chemistry, Multidisciplinary: 63/152 = 41.4 %)
    45. Jih-Jung Chen*, En-Tzu Chou, Chien-Fang Peng, Ih-Sheng Chen, Sheng-Zehn Yang, Hung-Yi Huang. Novel epoxyfuranoid lignans and antitubercular constituents from the leaves of Beilschmiedia tsangii. Planta Medica 2007, 73 (6), 567-571. {2007. 06} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    46. Jih-Jung Chen*, Hsinn-Hsing Lee, Cheng-Dean Shih, Chang-Hui Liao, Ih-Sheng Chen, Tsung-Hsien Chou. New dihydrochalcones and anti-platelet aggregation constituents from the leaves of Muntingia calabura. Planta Medica 2007, 73 (6), 572-577. {2007.06} (SCI, 2014 IF = 2.152) (Ranking in Plant Sciences: 55/195 = 28.2 %)
    47. Jih-Jung Chen*, Wen-Jiou Lin, Chang-Hui Liao, Po-Chuen Shieh. Anti-inflammatory benzenoids from Antrodia camphorata. Journal of Natural Products 2007, 70 (6), 989-992. {2007. 06} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    48. Tsung-Hsien Chou, Ih-Sheng Chen, Ping-Jyun Sung, Chien-Fang Peng, Po-Chuen Shieh, Jih-Jung Chen*. A new dihydroagarofuranoid sesquiterpene from Microtropis fokienensis with antituberculosis activity. Chemistry & Biodiversity 2007, 4 (7), 1594-1600. {2007. 07} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    49. Ping-Jyun Sung*, Li-Fan Chuang, Jimmy Kuo, Jih-Jung Chen, Tung-Yung Fan, Jan-Jung Li, Lee-Shing Fang, Wei-Hsien Wang. Rumphellolides A-F, six new caryophyllane-related derivatives from the Formosan gorgonian coral Rumphella antipathies. Chemical & Pharmaceutical Bulletin 2007, 55 (9), 1296-1301. {2007. 09} (SCI, 2012 IF = 1.564) (Ranking in Chemistry, Multidisciplinary: 63/152 = 41.4 %)
    50. Jih-Jung Chen*, Po-Hou Chen, Chang-Hui Liao, Shi-Yu Huang, Ih-Sheng Chen. New phenylpropenoids, bis(1-phenylethyl)phenols, bisquinolinone alkaloid, and anti-inflammatory constituents from Zanthoxylum integrifoliolum. Journal of Natural Products 2007, 70 (9), 1444-1448. {2007. 09} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    51. I-Li Chen, Ken-Ming Chang, Chang-Ling Miaw, Chang-Hui Liao, Jih-Jung Chen, Tai-Chi Wang*. Synthesis, antiproliferative, and antiplatelet activities of oxime- and amide-containing quinolin-2(1H)-one derivatives. Bioorganic & Medicinal Chemistry 2007, 15 (20), 6527-6534. {2007. 10} (SCI, 2012 Impact Factor = 2.903) (Ranking in Chemistry, Organic: 17/56 = 30.3 %)
    52. Jih-Jung Chen*, Jui-Ying Cho, Tsong-Long Hwang, Ih-Sheng Chen. Benzoic Acid Derivatives, Acetophenones, and Anti-inflammatory Constituents from Melicope semecarpifolia. Journal of Natural Products 2008, 71 (1), 71-75. {2008.01} (SCI, 2012 IF = 3.947) (Ranking in Plant Sciences: 27/190 = 14.2 %)
    53. Jih-Jung Chen*, Tzu-Ying Wang, Tsong-Long Hwang. Neolignans, a Coumarinolignan, Lignan Derivatives, and a Chromene: Anti-Inflammatory Constituents from Zanthoxylum avicennae. Journal of Natural Products 2008, 71 (2), 212-217. {2008. 02} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    54. Jih-Jung Chen*, Chang-Syun Yang, Chien-Fang Peng, Ih-Sheng Chen, and Chang-Ling Miaw. Dihydroagarofuranoid Sesquiterpenes, a Lignan Derivative, a Benzenoid, and Antitubercular Constituents from the Stem of Microtropis japonica. Journal of Natural Products 2008, 71 (6), 1016-1021. {2008. 06} (SCI, 2012 IF = 3.947) (Ranking in Plant Sciences: 27/190 = 14.2 %)
    55. Jih-Jung Chen*, Yu-Ting Luo, Tsong-Long Hwang, Ping-Jyun Sung, Tai-Chi Wang, Ih-Sheng Chen. A new indole alkaloid and anti-inflammatory constituents from Strychnos cathayensis. Chemistry & Biodiversity 2008, 5 (7), 1345-1352. {2008. 07} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    56. Tsung-Hsien Chou, Ih-Sheng Chen*, Chien-Fang Peng, Ping-Jyun Sung, and Jih-Jung Chen*. A new dihydroagarofuranoid sesquiterpene and antituberculosis constituents from the root of Microtropis japonica. Chemistry & Biodiversity 2008, 5 (7), 1412-1418. {2008. 07} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    57. I-Li Chen, Jhy-Yih Chen, Po-Chuen Shieh, Jih-Jung Chen, Choa-Hsun Lee, Shin-Hun Juang, Tai-Chi Wang*. Synthesis and antiproliferative evaluation of amide-containing flavone and isoflavone derivatives. Bioorganic & Medicinal Chemistry 2008, 16 (16), 7639-7645. {2008. 08} (SCI, 2012 IF = 2.903) (Ranking in Chemistry, Organic: 17/56 = 30.3 %)
    58. Ping-Jyun Sung*, Chen-Hao Pai, Tsong-Long Hwang, Tung-Yung Fan, Jui-Hsin Su, Jih-Jung Chen, Lee-Shing Fang, Wei-Hsien Wang, Jyh-Horng Sheu. Junceols D-H, New Polyoxygenated Briaranes from Sea Whip Gorgonian Coral Junceella juncea (Ellisellidae). Chemical & Pharmaceutical Bulletin 2008, 56 (9), 1276-1281. {2008. 09} (SCI, 2012 IF = 1.564) (Ranking in Chemistry, Multidisciplinary: 63/152 = 41.4 %)
    59. Tsung-Hsien Chou, Ih-Sheng Chen, Tsong-Long Hwang, Tai-Chi Wang, Tzong-Huei Lee, Lin-Yang Cheng, Ya-Chih Chang, Jui-Ying Cho, and Jih-Jung Chen*. Phthalides from Pittosporum illicioides var. illicioides with Inhibitory Activity on Superoxide Generation and Elastase Release by Neutrophils. Journal of Natural Products 2008, 71 (10), 1692-1695. {2008. 10} (SCI, 2012 IF = 3.947) (Ranking in Plant Sciences: 27/190 = 14.2 %)
    60. Ping-Shin Yang, Ming-Jen Cheng, Jih-Jung Chen, and Ih-Sheng Chen*. Two New Endiandric Acid Analogs, a New Benzopyran, and a New Benzenoid from the Root of Beilschmiedia erythrophloia. Helvetica Chimica Acta 2008, 91 (11), 2130-2138. {2008. 11} (SCI, 2012 IF = 1.383) (Ranking in Chemistry, Multidisciplinary: 69/152 = 45.3 %)
    61. Ping-Jyun Sung*, Yin-Di Su, Tsong-Long Hwang, Li-Fan Chuang, Jih-Jung Chen, Jan-Jung Li, Lee-Shing Fang, and Wei-Hsien Wang. Rumphellatin D, a Novel Chlorinated Caryophyllane from Gorgonian Coral Rumphella antipathies. Chemistry Letters 2008, 37 (12), 1244-1245. {2008. 12} (SCI, 2012 IF = 1.594) (Ranking in Chemistry, Multidisciplinary: 65/154 = 42.2 %)
    62. Ping-Shin Yang, Ming-Jen Cheng, Chien-Fang Peng, Jih-Jung Chen, and Ih-Sheng Chen*. Endiandric Acid Analogues from the Root of Belschmiedia erythrophloia. Journal of Natural Products 2009, 72 (1), 53-58. {2009. 01} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    63. Jih-Jung Chen*, Ching-Yi Chung, Tsong-Long Hwang, and Jinn-Fen Chen. Amides and Benzenoids from Zanthoxylum ailanthoides with Inhibitory Activity on Superoxide Generation and Elastase Release by Neutrophils. Journal of Natural Products 2009, 72 (1), 107-111. {2009. 01} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    64. Jih-Jung Chen*, Hung-Ming Wu, Chien-Fang Peng, Ih-Sheng Chen, and Shih-Der Chu. Seco-Abietane Diterpenoids, a Phenylethanoid Derivative, and Antitubercular Constituents from Callicarpa pilosissima. Journal of Natural Products 2009, 72 (2), 223-228. {2009. 02} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    65. Jih-Jung Chen*, Chia-Wei Ting, Tsong-Long Hwang, and Ih-Sheng Chen. Benzophenone Derivatives from the Fruits of Garcinia multiflora and Their Anti-inflammatory Activity. Journal of Natural Products 2009, 72 (2), 253-258. {2009. 02} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    66. Ping-Jyun Sung*, Yin-Di Su, Tsong-Long Hwang, Li-Fan Chuang, Hsu-Ming Chung, Jih-Jung Chen, Jan-Jung Li, Lee-Shing Fang, and Wei-Hsien Wang. Rumphellolide I, a Novel Caryophyllane-related Tetrahydropyran Norsesquiterpenoid from Gorgonian Coral Rumphella antipathies. Chemistry Letters 2009, 38 (3), 282-283. {2009. 02} (SCI, 2013 IF = 1.594) (Ranking in Chemistry, Multidisciplinary: 65/154 = 42.2 %)
    67. Jih-Jung Chen*, Yu-Ting Luo, Chang-Hui Liao, Ih-Sheng Chen, and Chih-Chuang Liaw. A New Dibenzofuran and Further Constituents from the Stems of Pourthiaea lucida with Inhibitory Activity on Superoxide Generation by Neutrophils. Chemistry & Biodiversity 2009, 6 (5), 774-778. {2009. 05} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 59/152 = 38.8 %)
    68. Ming-Jen Cheng, Ming-Der Wu, Ping-Shin Yang, Jih-Jung Chen, Ih-Sheng Chen*, Yen-Lin Chen, and Gwo-Fang Yuan. Secondary metabolites isolated from the fungus Monascus kaoliang-fermented rice. Journal of the Chilean Chemical Society 2010, 55 (1), 107-110. (SCI, 2013 IF = 0.376) (Ranking in Chemistry, Multidisciplinary: 118/144 = 81.9 %)
    69. Jih-Jung Chen*, Wen-Jiou Lin, Po-Chuen Shieh, Ih-Sheng Chen, Chien-Fang Peng, and Ping-Jyun Sung. A New Long-Chain Alkene and Antituberculosis Constituents from the Leaves of Pourthiaea lucida. Chemistry & Biodiversity 2010, 7 (3), 717-721. {2010. 03} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    70. Jih-Jung Chen*, Cheng-Shuan Tsai, Tsong-Long Hwang, Po-Chuen Shieh, Jinn-Fen Chen, Ping-Jyun Sung. Sesquiterpenes from the Rhizome of Curcuma longa with Inhibitory Activity on Superoxide Generation and Elastase Release by Neutrophils. Food Chemistry 2010, 119 (3), 974-980. {2010. 04}. (SCI, 2014 IF = 3.391) (Ranking in Food Science & Technology: 8/123 = 6.5 %) (Ranking in Chemistry, Applied: 8/70 = 11.4 %)
    71. Jih-Jung Chen*, Sheng-Shiou Huang, Chang-Hui Liao, Dau-Chang Wei, Ping-Jyun Sung, Tai-Chi Wang, Ming-Jen Cheng. A new phragmalin-type limonoid and anti-inflammatory constituents from the fruits of Swietenia macrophylla. Food Chemistry 2010, 120 (2), 379-384. {2010. 05}. (SCI, 2013 IF = 3.259) (Ranking in Food Science & Technology: 10/124 = 8.06 %) (Ranking in Chemistry, Applied: 9/71 = 7.88 %)
    72. Ping-Jyun Sung,* Bo-Yuan Chen, Michael Y. Chiang, Chi-Hung Hou, Yin-Di Su, Tsong-Long Hwang, Yung-Husan Chen, and Jih-Jung Chen. Excavatoids G–K, New 8,17-Epoxybriaranes from the Cultured Octocoral Briareum excavatum (Briareidae). Bulletin of the Chemical Society of Japan 2010, 83 (5), 539-545. {2010. 05} (SCI, 2013 IF = 1.387) (Ranking in Chemistry, Multidisciplinary: 71/152 = 46.7 %)
    73. Jui-Hsin Su, Bo-Yuan Chen, Tsong-Long Hwang, Yung-Husan Chen, I-Chu Huang, Mei-Ru Lin, Jih-Jung Chen, Lee-Shing Fang, Wei-Hsien Wang, Jan-Jung Li, Jyh-Horng Sheu, and Ping-Jyun Sung*. Excavatoids L–N, New 12-Hydroxybriaranes from the Cultured Octocoral Briareum excavatum (Briareidae). Chemical & Pharmaceutical Bulletin 2010, 58 (5), 662-665. {2010. 05} (SCI, 2013 Impact Factor = 1.375) (Ranking in Chemistry, Multidisciplinary: 76/148 = 51.4 %)
    74. Pei-Chi Pan, Ming-Jen Cheng, Chien-Fang Peng, Hung-Yi Huang, Jih-Jung Chen, and Ih-Sheng Chen*. Secondary Metabolites from the Roots of Litsea hypophaea and Their Antitubercular Activity. Journal of Natural Products 2010, 73 (5), 890-896. {2010. 05} (SCI, 2013 IF = 3.947) (Ranking in Plant Sciences: 21/199 = 10.55 %)
    75. Ming-Jen Cheng†, Jih-Jung Chen†, Ming-Der Wu*, and Gwo-Fang Yuan*. Isolation and structure determination of one new metabolite isolated from the red fermented rice of Monascus purpureus. Natural Product Research 2010, 24 (10), 979-988. {2010. 06} (†First two authors share equal contributions to this paper) (SCI, 2013 IF = 1.225) (Ranking in Chemistry, Applied: 38/71 = 53.5 %)
    76. Tzu-Ying Wang, Jin-Bin Wu*, Tsong-Long Hwang, Yueh-Hsiung Kuo, Jih-Jung Chen*. A New Quinolone and Other Constituents from the Fruits of Tetradium ruticarpum: Effects on Neutrophil Pro-Inflammatoty Responses. Chemistry & Biodiversity 2010, 7 (7), 1828-1834. {2010. 07}. (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    77. Ping-Jyun Sung*, Su-Hui Wang, Yu-Chia Chang, Yung-Husan Chen, Mei-Ru Lin, I-Chu Huang, Jih-Jung Chen, Jan-Jung Li, Ting-Hsuan Kung, Lee-Shing Fang, Wei-Hsien Wang, and Ching-Feng Weng. New Briarane-related Diterpenoids from the Sea Whip Gorgonian Coral Junceella fragilis (Ellisellidae). Bulletin of the Chemical Society of Japan 2010, 83 (9), 1074-1078. {2010. 09} (SCI, 2013 IF = 2.222) (Ranking in Chemistry, Multidisciplinary: 54/148 = 36.49 %)
    78. Tsung-Hsien Chou, Jih-Jung Chen, Shiow-Ju Lee, Michael Y. Chiang, Cheng-Wei Yang, and Ih-Sheng Chen*. Cytotoxic Flavonoids from the Leaves of Cryptocarya chinensis. Journal of Natural Products 2010, 73 (9), 1470-1475 {2010. 09} (SCI, 2013 IF = 3.947) (Ranking in Plant Sciences: 21/199 = 10.55 %)
    79. Hsu-Ming Chung, Tsong-Long Hwang, Yung-Husan Chen, Jui-Hsin Su, Mei-Chin Lu, Jih-Jung Chen, Jan-Jung Li, Lee-Shing Fang, Wei-Hsien Wang, Ping-Jyun Sung*. Rumphellclovane B, a Novel Clovane Analogue from the Gorgonian Coral Rumphella antipathies. Bulletin of the Chemical Society of Japan 2011, 84 (1), 119-121. {2011. 01} (SCI, 2013 IF = 2.222) (Ranking in Chemistry, Multidisciplinary: 54/148 = 36.49 %)
    80. Jih-Jung Chen*, Yu-Hsien Lin†, Shiow-Hwa Day†, Tsong-Long Hwang†, Ih-Sheng Chen. New benzenoids and anti-inflammatory constituents from Zanthoxylum nitidum. Food Chemistry 2011, 125 (2), 282-287. {2011. 03} (†Authors have contributed equally in this manuscript.) (SCI, 2013 IF = 3.259) (Ranking in Food Science & Technology: 10/123 = 8.13 %) (Ranking in Chemistry, Applied: 9/71 = 7.88 %)
    81. Chang-Hui Liao*, Jih-Jung Chen, Jieru Egeria Lin, Chia-Hsin Liu, Ching-Ping Tseng and Yuan-Ji Day. 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one (MSF-2) suppresses fMLP-mediated respiratory burst in human neutrophils by inhibiting phosphatidylinositol 3-kinase activity. Journal of Cellular Physiology 2011, 226 (6), 1519-1530. {2011. 03} (SCI, 2013 IF = 3.874) (Ranking in Physiology: 14/81 = 17.28 %)
    82. Jih-Jung Chen*, Hsin-Chih Hung, Ping-Jyun Sung, Ih-Sheng Chen, Wen-Long Kuo. Aporphine alkaloids and cytotoxic lignans from the roots of Illigera luzonensis. Phytochemistry 2011, 72 (6), 523-532. {2011. 04} (SCI, 2013 Impact Factor = 3.350) (Ranking in Plant Sciences: 22/190 = 11.57 %)
    83. Jih-Jung Chen*, Yun-Chen Tsai, Tsong-Long Hwang, and Tai-Chi Wang. Thymol, benzofuranoid, and phenylpropanoid derivatives: Anti-inflammatory constituents from Eupatorium cannabinum. Journal of Natural Products 2011, 74 (5), 1021-1027. {2011. 05} (SCI, 2013 IF = 3.947) (Ranking in Plant Sciences: 21/199 = 10.55 %)
    84. Chia-Ying Kao, Jui-Hsin Su, Mei-Chin Lu, Tsong-Long Hwang, Wei-Hsien Wang, Jih-Jung Chen, Jyh-Horng Sheu, Yueh-Hsiung Kuo, Ching-Feng Weng, Lee-Shing Fang, Zhi-Hong Wen, Ping-Jyun Sung*. Lobocrassins A–E, New Cembrane-type Diterpenoids from the Soft Coral Lobophytum aphtha. Marine Drugs 2011, 9, 1319-1331. {2011. 08} (SCI, 2013 IF = 3.512) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    85. Ming-Der Wu*, Ming-Jen Cheng, Wei-Yi Wang, Hui-Chun Huang, Gwo-Fang Yuan*, Jih-Jung Chen, Ih-Sheng Chen, and Bor-Cheh Wang*. Antioxidant activities of extracts and metabolites isolated from the fungus Antrodia cinnamomea. Natural Product Research 2011, 25 (16), 1488-1496. {2011. 09} (SCI, 2013 IF = 1.225) (Ranking in Chemistry, Applied: 38/71 = 53.5 %)
    86. Jui-Ying Cho, Tzong-Huei Lee*, Tsong-Long Hwang, Sheng-Zehn Yang, Ih-Sheng Chen, Tsung-Hsien Chou, Ping-Jyun Sung, and Jih-Jung Chen*. A New Ferulic Acid Ester, a New Ellagic Acid Derivative, and Other Constituents from Pachycentria formosana: Effects on Neutrophil Pro-Inflammatory Responses. Chemistry & Biodiversity 2011, 8 (9), 1709-1716. {2011. 09} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    87. Tsung-Hsien Chou, Jih-Jung Chen, Chien-Fang Peng, Ming-Jen Cheng, and Ih-Sheng Chen*. New Flavanones from the Leaves of Cryptocarya chinensis and Their Antituberculosis Activity. Chemistry & Biodiversity 2011, 8 (11), 2015-2024. {2011. 11} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    88. Chia-Wei Ting, Tsong-Long Hwang, Ih-Sheng Chen, Ming-Hong Yen*, and Jih-Jung Chen*. A new benzoylphloroglucinol derivative with an adamantyl skeleton and other constituents from Garcinia multiflora: Effects on neutrophil pro-inflammatoty responses. Chemistry & Biodiversity 2012, 9 (1), 99-105. {2012. 01} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    89. Pei-Han Hong, Yin-Di Su, Nai-Cheng Lin, Yung-Husan Chen, Yueh-Hsiung Kuo, Tsong-Long Hwang, Wei-Hsien Wang, Jih-Jung Chen, Jyh-Horng Sheu*, Ping-Jyun Sung*. Briarenolide E: The first 2-ketobriarane diterpenoid from an octocoral Briareum sp. (Briareidae). Tetrahedron Letters 2012, 53 (14), 1710-1712. {2012. 04} (SCI, 2012 IF = 2.397) (Ranking in Chemistry, Organic: 19/56 = 33.9 %)
    90. Yun-Ping Lim*, Chia-Yun Ma, Cheng-Ling Liu, Yu-Hsien Lin, Miao-Lin Hu, Jih-Jung Chen, Dong-Zong Hung, Wen-Tsong Hsieh, Jin-Ding Huang. Sesamin: A naturally occurring aphth inhibits CYP3A4 by antagonizing of the pregnane X receptor activation. Evidence-based Complementary and Alternative Medicine 2012, 2012, Article ID 242810, 15 pages. {2012. 05} (SCI, 2012 IF = 1.722) (Ranking in Integrative & Complementary Medicine: 1/22 = 4.5 %)
    91. Hsu-Ming Chung, Pei-Han Hong, Jui-Hsin Su, Tsong-Long Hwang, Mei-Chin Lu, Lee-Shing Fang, Yang-Chang Wu, Jan-Jung Li, Jih-Jung Chen, Wei-Hsien Wang*, Ping-Jyun Sung*. Bioactive Compounds from a Gorgonian Coral Echinomuricea sp. (Plexauridae). Marine Drugs 2012, 10 (5), 1169-1179. {2012. 05} (SCI, 2013 IF = 3.512) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    92. Tsung-Hsien Chou, Sheng-Kan Chien, Tsong-Long Hwang, Dau-Chang Wei, Ih-Sheng Chen, Ping-Jyun Sung, Ming-Jen Cheng, Sheng-Zehn Yang, Ken-Ming Chang, Jih-Jung Chen*. Orthoquinone and Naphthalenone Derivatives from Berrya ammonilla and Their Anti-inflammatory Activity. Planta Medica 2012, 78 (9), 919-925. {2012. 06} (SCI, 2015 IF = 1.990) (Ranking in Plant Sciences: 70/209 = 33.4 %)
    93. Hsiang-Ruei Liao, Jih-Jung Chen, Yin-Huan Chien, Shinn-Zhi Lin, Shunchih Lin, Ching-Ping Tseng. 5-Hydroxy-7-methoxyflavone inhibits N-formyl-L-methionyl-L-leucyl-L-phenylalanine- induced superoxide anon production by specific modulate membrane localization of Tec with a PI3K independent mechanism in human neutrophils. Biochemical Pharmacology 2012, 84 (2), 182-191. {2012. 07} (SCI, 2013 IF = 4.576) (Ranking in Pharmacology & Phamacy: 28/261 = 10.7 %)
    94. Ming-Jen Cheng*, Ming-Der Wu, Hiromasa Yanai, Yung-Shun Su, Ih-Sheng Chen, Gwo-Fang Yuan, Sung-Yuan Hsieh, Jih-Jung Chen. Secondary metabolites from the endophytic fungus Biscogniauxia formosana and their antimycobacterial activity. Phytochemistry Letters 2012, 5 (3), 467–472. {2012. 09} (SCI, 2013 IF = 1.542) (Ranking in Plant Sciences: 88/199 = 44.22 %)
    95. Jui-Ying Cho, Tsong-Long Hwang, Tsung-Hsien Chang, Lim Yun Ping, Ping-Jyun Sung, Tzong-Huei Lee*, Jih-Jung Chen*. New coumarins and anti-inflammatory constituents from Zanthoxylum avicennae. Food Chemistry 2012, 135 (1), 17-23. {2012. 11} (SCI, 2015 IF = 4.052) (Ranking in Food Science & Technology: 10/123 = 8.13 %) (Ranking in Chemistry, Applied: 9/71 = 12.7 %)
    96. Wen-Lung Kuo, Ching-Yi Chung, Tsong-Long Hwang, Jih-Jung Chen*. Biphenyl-type neolignans from Magnolia officinalis and their anti-inflammatory activities. Phytochemistry 2013, 85, 153-160. {2013. 01} (SCI, 2015 IF = 2.779) (Ranking in Plant Sciences: 44/209 = 21.0 %)
    97. I-Li Chen, Jih-Jung Chen, Yu-Chin Lin, Ching-Tien Pern, Shin-Hun Juang*, Tai-Chi Wang*. Synthesis and antiproliferative activities of N-(aphthalene-2-yl)acetamide and N-(substituted phenyl)acetamide bearing quinolin-2(1H)-one and 3,4-dihydroquinolin-2(1H)-one derivatives. European Journal of Medicinal Chemistry 2013, 59, 227-234. {2013. 01} (SCI, 2012 Impact Factor = 3.499) (Ranking in Chemistry, Medicinal: 13/59 = 22 %)
    98. Yao-Shen Chen, Bao-Chen Chen, You-Sheng Lin, Jenn-Tzong Chang, Tsi-Shu Huang, Jih-Jung Chen, Tsung-Hsien Chang. Detection of Aichi virus with antibody targeting of conserved viral protein 1 Epitope. Applied Microbiology and Biotechnology 2013, published on line. {2013. 01} (SCI, 2015 Impact Factor = 3.376) (Ranking in Biotechnology & Applied Microbiology: 39/158 = 24.7 %)
    99. Ming-Der Wu*, Ming-Jen Cheng*, Yi-Jen Yecha, Gwo-Fang Yuan*, Jih-Jung Chen. Inhibitory Effects of Maleimide Derivatives from the Mycelia of the Fungus Antrodia cinnamomea BCRC 36799 on Nitric Oxide Production in Lipopolysaccharide (LPS)-Activated RAW264.7 Macrophages. Chemistry & Biodiversity 2013, 10 (3), 434-441. {2013. 03} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    100. Hsu-Ming Chung, Jui-Hsin Su, Tsong-Long Hwang, Jan-Jung Li, Jih-Jung Chen, Yung-Husan Chen, Yu-Chia Chang, Yin-Di Su, Yu-Hsin Chen, Lee-Shing Fang, Jyh-Horng Sheu, Wei-Hsien Wang*, Ping-Jyun Sung*. Rumphellclovanes C−E, new clovane-type sesquiterpenoids from the gorgonian coral Rumphella antipathies. Tetrahedron 2013, 69 (13), 2740-2744. {2013. 04} (SCI, 2015 Impact Factor = 2.645) (Ranking in Chemistry, Organic: 16/56 = 28.6 %)
    101. Jih-Jung Chen*, Chia-Wei Ting, Yi-Chin Wu, Tsong-Long Hwang, Ming-Jen Cheng, Ping-Jyun Sung, Tai-Chi Wang, and Jinn-Fen Chen. New labdane-type diterpenoids and anti- inflammatory constituents from Hedychium coronarium. International Journal of Molecular Sciences 2013, 14 (7), 13063-13077. {2013. 06} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %)
    102. Ming-Jen Cheng*, Ming-Der Wu, Ih-Sheng Chen, Jih-Jung Chen, Sung-Yuan Hsieh, Gwo-Fang Yuan. A new furan-3-one derivative from the endophytic fungus Annulohypoxylon sp. Chemistry of Natural Compounds 2013, 49 (3), 446-449. {2013. 07} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    103. Kuan-Hua Chen, Chang-Feng Dai, Mei-Chin Lu, Jan-Jung Li, Jih-Jung Chen, Yu-Chia Chang, Yin-Di Su, Wei-Hsien Wang, Ping-Jyun Sung*. Secondary Metabolites from the Soft Coral Sinularia arborea. Marine Drugs 2013, 11 (9), 3372-3380. {2013. 09} (SCI, 2013 IF = 3.512) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    104. Ming-Jen Cheng*, Min Tseng, Jih-Jung Chen, Gwo-Fang Yuan, Ih-Sheng Chen. Secondary metabolites from the actinomycete Acrocarpospora punica. Chemistry of Natural Compounds 2013, 49 (4), 777-779. {2013. 09} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    105. Jih-Jung Chen*, Tai-Chi Wang, Chieh-Kai Yang, Hsiang-Ruei Liao, Ping-Jyun Sung, Ih-Sheng Chen, Ming-Jen Cheng, Chien-Fang Peng, and Jinn-Fen Chen. New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis. Chemistry & Biodiversity 2013, 10 (10), 1903-1908. {2013. 10} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    106. Ching-Yi Chung, Tsong-Long Hwang, Liang-Mou Kuo, Wen-Lung Kuo, Ming-Jen Cheng, Yi-Hsiu Wu, Ping-Jyun Sung, Mei-Ing Chung*, and Jih-Jung Chen*. New benzo[c]phenan- thridine and benzenoid derivatives, and other constituents from Zanthoxylum ailanthoides: Effects on neutrophil pro-inflammatory responses. International Journal of Molecular Sciences 2013, 14 (11), 22395-22408. {2013. 11} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %)
    107. Li-Chai Chen, Shin-Hun Juang, Ken-Ming Chang, Cherng-Chyi Tzeng, Jih-Jung Chen, I-Li Chen*, and Tai-Chi Wang*. Synthesis and antiproliferative evaluation of amide-containing anthraquinone, xanthone, and carbazole. Chemical & Pharmaceutical Bulletin 2014, 62 (1), 106-111. {2014. 01} (SCI, 2013 IF = 1.375) (Ranking in Chemistry, Multidisciplinary: 76/148 = 51.3 %)
    108. Kuan-Hua Chen, Chang-Feng Dai, Tsong-Long Hwang, Chun-Yu Chen, Jan-Jung Li, Jih-Jung Chen, Yang-Chang Wu, Jyh-Horng Sheu, Wei-Hsien Wang, Ping-Jyun Sung*. Discovery of novel diterpenoids from Sinularia arborea. Marine Drugs 2014, 12 (1), 385-393. {2014. 01} (SCI, 2015 IF = 3.345) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    109. Chen-Pin Chou, Nan-Chieh Huang, Shu-Jhen Jhuang, Huay-Ben Pan, Nan-Jing Peng, Jiin-Tsuey Cheng, Chian-Feng Chen, Jih-Jung Chen, Tsung-Hsien Chang. Ubiquitin- conjugating Enzyme UBE2C is Highly Expressed in Breast Microcalcification Lesions. PLOS ONE 2014, 9 (4), e93934. {2014. 04} (SCI, 2013 IF = 3.730) (Ranking in Multidisciplinary Sciences: 7/56 = 12.5 %)
    110. Tzong-Huei Lee†, Yuan-Chih Chen†, Tsong-Long Hwang, Chih-Wen Shu, Ping-Jyun Sung, Yun-Ping Lim, Wen-Lung Kuo, Jih-Jung Chen*. New Coumarins and Anti-Inflammatory Constituents from the Fruits of Cnidium monnieri. International Journal of Molecular Sciences 2014, 15 (6), 9566-9578. {2014. 05} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %) (†Authors have contributed equally in this manuscript.)
    111. Ming-Jen Cheng*, Ming-Der Wu, Jih-Jung Chen, Yen-Chen Cheng, Sung-Yuan Hsieh, Gwo-Fang Yuan*, Yung-Shun Su. Secondary metabolites from the endophytic fungus Annulohypoxylon stygium BCRC 34024. Chemistry of Natural Compounds 2014, 50 (2), 237-241. {2014. 05} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    112. Jih-Jung Chen, Shih-Wei Wang, Hui-Yun Hsiao, Ming-Shian Lee, Yu-Min Ju, Yueh-Hsiung Kuo, Tzong-Huei Lee*. Aliphatic Phenolic Ethers from Trichobotrys effusa. Journal of Natural Products 2014, 75 (5), 1097-1101. {2014. 05} (SCI, 2014 IF = 3.798) (Ranking in Plant Sciences: 23/200 = 11.5 %)
    113. Chia-Wei Ting , Tsong-Long Hwang , Ih-Sheng Chen , Ming-Jen Cheng , Ping-Jyun Sung , Ming-Hong Yen*, and Jih-Jung Chen*. Garcimultiflorone G, a novel benzoylphloroglucinol derivative from Garcinia multiflora with inhibitory activity on neutrophil pro-inflammatoty responses. Chemistry & Biodiversity 2014, 11 (5), 819-824. {2014. 05} (SCI, 2015 IF = 1.444) (Ranking in Chemistry, Multidisciplinary: 90/163 = 55.2 %)
    114. Li-Min Liu, Shu-Fen Cheng, Po-Chuen Shieh, Jang-Chang Lee, Jih-Jung Chen, Chi-Tang Ho, Sheng-Chu Kuo, Daih-Huang Kuo, Li-Jiau Huang, Tzong-Der Way. The methanol extract of Euonymus laxiflorus, Rubia lanceolata and Gardenia jasminoides inhibits xanthine oxidase and reduce serum uric acid level in rats. Food and Chemical Toxicology 2014, 70, 179-184. {2014. 05} (SCI, 2012 IF = 3.010) (Ranking in Multidisciplinary Sciences: 12/124 = 9.68 %)
    115. Jih-Jung Chen*, Wen-Lung Kuo, Ih-Sheng Chen, Chien-Fang Peng, Ping-Jyun Sung, Ming-Jen Cheng, and Yun-Ping Lim. Microjaponin, A New Dihydroagarofuranoid Sesquiterpene from the Stem of Microtropis japonica with Antituberculosis Activity. Chemistry & Biodiversity 2014, 11 (8), 1241-1246. {2014. 08} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    116. Yun-Ping Lim*, Wei-Cheng Chen, Ching-Hao Cheng, Wei-Chih Ma, Yu-Hsien Lin, Cing-Yu Chen, Dong-Zong Hung, Jih-Jung Chen, Tsuyoshi Yokoi, Miki Nakajima, Chao-Jung Chen*. Inhibition of cytochrome P450 2C9 (CYP2C9) expression and activity in vitro by allyl isothiocyanate (AITC). Planta Medica 2014, 80 (13), 1097-1106. (SCI, 2013 IF = 2.339) {2014. 08} (Ranking in Plant Sciences: 60/196 = 30.6 %)
    117. Chung-Man Leung, Pei-Feng Liu, Yu-Hsiang Chang, Jin-Shiung Cheng, Jih-Jung Chen, Chung-Jeu Weng, Kuo-Wang Tsai, Chien-Jen Hsu, Yen-Chen Liu, Ping-Chi Hsu, Hung-Wei Pan, Chih-Wen Shu*. ATG4B promotes colorectal cancer growth independent of autophagic flux. Autophagy 2014, 10 (8), 1454-1465. {2014. 08} (SCI, 2015 IF = 9.108) (Ranking in Cell Biology: 15/185 = 8.1%)
    118. Li-Chai Chen, Tzong-Huei Lee, Ping-Jyun Sung, Chih-Wen Shu, Yun-Ping Lim, Ming-Jen Cheng, Wen-Lung Kuo, Jih-Jung Chen*. New Thymol Derivatives and Cytotoxic Constituents from the Root of Eupatorium cannabinum ssp. asiaticum. Chemistry & Biodiversity 2014, 11 (9), 1374-1380. {2014. 09} (SCI, 2014 IF = 1.515) (Ranking in Chemistry, Multidisciplinary: 76/157 = 48.4 %)
    119. Hsu-Ming Chung, Wei-Hsien Wang, Tsong-Long Hwang, Jih-Jung Chen, Lee-Shing Fang, Zhi-Hong Wen, Yu-Bao Wang, Yang-Chang Wu* and Ping-Jyun Sung*. Rumphellols A and B, New Caryophyllene Sesquiterpenoids from a Formosan Gorgonian Coral, Rumphella antipathies. International Journal of Molecular Sciences 2014, 15 (9), 15679-15688. {2014. 09} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %)
    120. Yin-Di Su, Ching-Hsiao Cheng, Wu-Fu Chen, Yu-Chia Chang, Yu-Hsin Chen, Tsong-Long Hwang, Zhi-Hong Wen, Wei-Hsein Wang, Lee-Shing Fang, Jih-Jung Chen, Yang-Chang Wu, Jyh-Horng Sheu*, Ping-Jyun Sung*. Briarenolide J, the first 12-chlorobriarane diterpenoid from an octocoral Briareum sp. (Briareidae). Tetrahedron Letters 2014, 55 (44), 6065-6067. {2014.10} (SCI, 2013 IF = 2.391) (Ranking in Chemistry, Organic: 24/58 = 41.4 %)
    121. Jih-Jung Chen*, Ming-Jen Cheng, Chang-Hui Liao, Ping-Jyun Sung, Tai-Chi Wang, Tsung-Hsien Chang, Yun-Ping Lim. Gmelinoiridoside, a new iridoid glycoside from Gmelina philippensis. Chemistry of Natural Compounds 2014, 50 (6), 1005-1008. {2014. 11} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    122. Jih-Jung Chen, Hong-Jhang Chen, and Yun-Lian Lin*. Novel Polyprenylated Phloroglucinols from Hypericum sampsonii. Molecules 2014, 19 (12), 19836-19844. {2014. 12} (SCI, 2015 IF = 2.465) (Ranking in Chemistry, Organic: 24/59 = 40.6 %)
    123. Hsu-Ming Chung, Wei-Hsien Wang, Tsong-Long Hwang, Lee-Shing Fang, Zhi-Hong Wen, Jih-Jung Chen, Yang-Chang Wu* and Ping-Jyun Sung*. Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies. Marine Drugs 2014, 12 (12), 5856-5863. {2014. 12} (SCI, 2015 IF = 3.345) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    124. Wen-Lung Kuo*, Hsiang-Ruei Liao, Jih-Jung Chen*. Biflavans, flavonoids, and dihydro- chalcone from the stem wood of Muntingia calabura and their inhibitory activities on neutrophil pro-inflammatoty responses. Molecules 2014, 19 (12), 20521-20535. {2014.12} (SCI, 2015 IF = 2.465) (Ranking in Chemistry, Organic: 24/59 = 40.6 %)
    125. Tzong-Huei Lee, Chien-Chih Chen, Jih-Jung Chen, Hui-Fen Liao, Hsun-Shuo Chang, Ping-Jyun Sung, Mei-Hwei Tseng, Sheng-Yang Wang, Horng-Huey Ko, Yueh-Hsiung Kuo*. New and cytotoxic components from Antrodia camphorate. Molecules 2014, 19 (12), 21378- 21385. {2014.12} (SCI, 2015 IF = 2.465) (Ranking in Chemistry, Organic: 24/59 = 40.6 %)
    126. Yun-Ping Lim*, Ching-Hao Cheng, Wei-Cheng Chen, Shih-Yu Chang, Dong-Zong Hung, Jih-Jung Chen, Lei Wan, Wei-Chih Ma, Yu-Hsien Lin, Cing-Yu Chen, Tsuyoshi Yokoi, Miki Nakajima, Chao-Jung Chen*. Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity. Archives of Toxicology 2015, 89 (1), 57-72. {2015. 01} (SCI, 2015 IF = 6.637) (Ranking in Toxicology: 6/85 = 7.0 %)
    127. Ming-Jen Cheng*, Ming-Der Wu, Yen-Chen Cheng, Jih-Jung Chen*, Sung-Yuan Hsieh, Gwo-Fang Yuan*, Yung-Shun Su. Metabolites isolated from an endophytic fungus of Annulohypoxylon elevatidiscus. Chemistry of Natural Compounds 2015, 51 (1), 67-70. {2015. 01} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    128. Yin-Di Su, Tzu-Rong Su, Zhi-Hong Wen, Tsong-Long Hwang, Lee-Shing Fang, Jih-Jung Chen, Yang-Chang Wu, Jyh-Horng Sheu*, Ping-Jyun Sung*. Briarenolides K and L, New Anti- inflammatory Briarane Diterpenoids from an Octocoral Briareum sp. (Briareidae). Marine Drugs 2015, 13 (2), 1037-1050. {2015. 02} (SCI, 2013 IF = 3.512) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    129. Wu-Fu Chen, Chen-Ting Yin, Ching-Hsiao Cheng, Mei-Chin Lu, Lee-Shing Fang, Wei-Hsien Wang, Zhi-Hong Wen, Jih-Jung Chen, Yang-Chang Wu*, and Ping-Jyun Sung*. Norcembranoidal Diterpenes from the Cultured-Type Octocoral Sinularia numerosa. International Journal of Molecular Sciences 2015, 16 (2), 3298-3306. {2015. 02} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %)
    130. Jih-Jung Chen*, Ping-Jyun Sung, Ih-Sheng Chen, Ming-Jen Cheng, Yun-Ping Lim, Hsiang-Ruei Liao, Tsung-Hsien Chang, Dau-Chang Wei, and Jhy-Yih Chen. Beilschamide, a new amide and cytotoxic constituents from Beilschmiedia erythrophloia. Chemistry of Natural Compounds 2015, 51 (2), 302-305. {2015. 03} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    131. Li-Fong Wang, You-Sheng Lin, Nan-Chieh Huang, Chia-Yi Yu, Wei-Lun Tsai, Jih-Jung Chen, Toru Kubota, Mayumi Matsuoka, Siang-Ru Chen, Chih-Shiang Yang, Ruo-Wei Lu, Yi-Ling Lin and Tsung-Hsien Chang*. Hydroxychloroquine-inhibited Dengue Virus is Associated with Host Defense Machinery. Journal of Interferon and Cytokine Research 2015, 35 (3), 143-156. {2015.03} (SCI, 2015 IF = 2.135) (Ranking in Immunology: 42/144 = 29.2 %)
    132. Chia-ling Chen, I-Li Chen, Jih-Jung Chen, Dau-Chang Wei, Han-Jie Hsieh, Ken-Ming Chang, Cherng-Chyi Tzeng, Tai-Chi Wang*. Studies on the alkylation of quinolin-2(1H)-one derivatives. Journal of the Chilean Chemical Society 2015, 60 (1), 2812-2816. {2015.03} (SCI, 2013 IF = 0.376) (Ranking in Chemistry, Multidisciplinary: 118/144 = 81.9 %)
    133. Jih-Jung Chen*, Chieh-Kai Yang , Yueh-Hsiung Kuo, Tsong-Long Hwang, Wen-Lung Kuo, Yun-Ping Lim, Ping-Jyun Sung , Tsung-Hsien Chang , and Ming-Jen Cheng. New Coumarin Derivatives and Other Constituents from the Stem Bark of Zanthoxylum avicennae: Effects on Neutrophil Pro-Inflammatory Responses. International Journal of Molecular Sciences 2015, 16 (5), 9719-9731. {2015. 05} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %)
    134. Wen-Lung Kuo*, Fa-Ching Chen, Kwei-Ju Chen, and Jih-Jung Chen*. Taxusumatrin, a new taxoid from the stem bark of Taxus sumatrana. Chemistry of Natural Compounds 2015, 51 (3), 427-430. {2015. 05} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    135. Hsiang-Ruei Liao*, Ching-Ru Chien, Jih-Jung Chen, Tzung-Yan Lee, Shinn-Zhi Lin, Ching-Ping Tseng. The anti-inflammatory effect of 2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop- 2-enyl-phenol by targeting Lyn kinase in human neutrophils. Chemico-Biological Interactions 2015, 236, 90-101. {2015. 05} (SCI, 2015 IF = 2.618) (Ranking in Pharmacology & Pharmacy: 79/256 = 30.86 %)
    136. Ming-Jen Cheng*, Ming-Der Wu, Hing-Yuen Chan*, Sung-Yuan Hsieh, Yen-Lin Chen, Ih-Sheng Chen, Fu-Ling Chan, Jih-Jung Chen, Gwo-Fang Yuan. Secondary metabolites produced by Phomopsis sp. 11F0023, an endophytic fungus in Eragrostis amabilis. Chemistry of Natural Compounds 2015, 51 (3), 431-434. {2015.05} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    137. Ming-Jen Cheng*, Hing-Yuen Chan*, Yen-Chen Cheng, Ming-Der Wu, Jih-Jung Chen, Yen-Lin Chen, Sung-Yuan Hsieh, Gwo-Fang Yuan, Yung-Shun Su. A new pyrrole metabolite from the endophytic fungus Xylaria papules. Chemistry of Natural Compounds 2015, 51 (3), 515-518. {2015.05} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    138. Tzong-Huei Lee, Ming-Shian Lee, Horng-Huey Ko, Jih-Jung Chen, Hsun-Shuo Chang, Mei-Hwei Tseng, Sheng-Yang Wang, Chien-Chih Chen, and Yueh-Hsiung Kuo*. New Furanone and Sesquiterpene from the Pericarp of Calocedrus formosana. Natural Product Communications 2015, 10 (6), 845-846. {2015.06} (SCI, 2014 IF = 0.906)
    139. Ya-Yuan Lai, Mei-Chin Lu, Li-Hsueh Wang, Jih-Jung Chen, Lee-Shing Fang, Yang-Chang Wu*, Ping-Jyun Sung*. New Scalarane Sesterterpenoids from the Formosan Sponge Ircinia felix. Marine Drugs 2015, 13 (7), 4296-4309. {2015. 07} (SCI, 2014 IF = 2.853) (Ranking in Chemistry, Medicinal: 10/58 = 17.2 %)
    140. Jih-Jung Chen*, Tzong-Huei Lee, Wen-Lung Kuo, Ping-Jyun Sung, Ih-Sheng Chen, Chih-Wen Shu, Ming-Jen Cheng, Tai-Chi Wang, Yun-Ping Lim, Rong Xu. (+)-(6aR,7R)-7-Hydroxy-N- butyrylcaaverine, a new aporphine alkaloid from the root of Illigera luzonensis with cytotoxic activity. Chemistry of Natural Compounds 2015, 51 (4), 739-742. {2015. 07} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    141. Ching-Yi Chung, Wen-Lung Kuo, Tsong-Long Hwang, Mei-Ing Chung*, and Jih-Jung Chen*. Biphenyl-type neolignan derivatives from the twigs of Magnolia denudata and their anti-inflammatory activity. Chemistry & Biodiversity 2015, 12 (8), 1263-1270. {2015. 08} (SCI, 2013 IF = 1.795) (Ranking in Chemistry, Multidisciplinary: 63/148 = 42.6 %)
    142. Wun-Jie Lin, Tung-Ying Wu, Tzu-Rong Su, Zhi-Hong Wen, Jih-Jung Chen, Lee-Shing Fang , Yang-Chang Wu*, and Ping-Jyun Sung*. Terpenoids from the Octocoral Sinularia gaweli. International Journal of Molecular Sciences 2015, 16 (8), 19508-19517. {2015. 08} (SCI, 2014 IF = 2.862) (Ranking in Chemistry, Multidisciplinary: 45/157 = 28.7 %)
    143. I-Fei Huang, I-Chun Lin, Pei-Feng Liu, Ming-Fang Cheng, Yen-Chen Liu, Yao-Dung Hsieh, Jih-Jung Chen, Chun-Lin Chen, Hsueh-Wei Chang, Chih-Wen Shu*. Lactobacillus acidophilus attenuates Salmonella-induced intestinal inflammation via TGF-β signaling. BMC Microbiology 2015, 15: 203. {2015. 10} (SCI, 2014 IF = 2.729) (Ranking in Microbiology: 51/119 = 42.8 %)
    144. Li-Chai Chen†, Hsiang-Ruei Liao†, Pei-Yu Chen, Wen-Lung Kuo, Tsung-Hsien Chang, Ping-Jyun Sung, Zhi-Hong Wen†, Jih-Jung Chen*. Limonoids from the Seed of Swietenia macrophylla and their Anti-Inflammatory Activities. Molecules 2015, 20 (10), 18551- 18564. {2015.10} (SCI, 2015 IF = 2.465) (Ranking in Chemistry, Organic: 24/59 = 40.6 %). (†Authors have contributed equally in this manuscript.)
    145. Sin-Ling Wang†, Tsong-Long Hwang, Mei-Ing Chung†, Ping-Jyun Sung, Chih-Wen Shu, Ming-Jen Cheng, and Jih-Jung Chen*. New flavones, a 2-(2-phenylethyl)-4H-chromen-4-one derivative, and anti-inflammatory constituents from the stem barks of Aquilaria sinensis. Molecules 2015, 20 (11), 20912-20925. {2015.11} (SCI, 2014 IF = 2.416) (Ranking in Chemistry, Organic: 21/57 = 36.8 %). (†Authors have contributed equally in this manuscript.)
    146. Ming-Jen Cheng*, Ming-Der Wu, Hing-Yuen Chan*, Yen-Chen Cheng, Jih-Jung Chen, Yen-Lin Chen, Ih-Sheng Chen, Gwo-Fang Yuan. New metabolite from the fungus Monascus kaoliang. Chemistry of Natural Compounds 2015, 51 (6), 1091-1093. {2015. 11} (SCI, 2014 IF = 0.509) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    147. Fang-Pin Chang, Chien-Chih Chen, Hui-Chi Huang, Sheng-Yang Wang, Jih-Jung Chen, Chang-Syun Yang, Chung-Yi Ou, Jin-Bin Wu, Guan-Jhong Huang, Yueh-Hsiung Kuo*. A new bithiophene from the root of Echinops grijsii. Natural Product Communications 2015, 10 (12), 2147-2149. {2015. 12} (SCI, 2015 IF = 0.884) (Ranking in Chemistry, Medicinal: 52/59 = 88.1 %). (Ranking in Food Science & Technology: 76/123 = 61.8 %)
    148. Yin-Di Su, Chun-Sung Sung, Zhi-Hong Wen, Yu-Hsin Chen, Yu-Chia Chang, Jih-Jung Chen, Lee-Shing Fang, Yang-Chang Wu*, Jyh-Horng Sheu* and Ping-Jyun Sung*. New 9-Hydroxybriarane Diterpenoids from a Gorgonian Coral Briareum sp. (Briareidae). International Journal of Molecular Sciences 2016, 17, 79; doi:10.3390/ijms17010079. {2016. 01} (SCI, 2015 IF = 3.257) (Ranking in Chemistry, Multidisciplinary: 52/163 = 31.9 %)
    149. Ming-Jen Cheng*, Ming-Der Wu, Hing-Yuen Chan*, Jih-Jung Chen*, Yen-Chen Cheng, Yen-Lin Chen, Ih-Sheng Chen, and Gwo-Fang Yuan. One new azaphilone metabolite from the fungus Monascus ruber. Chemistry of Natural Compounds 2016, 52 (2), 231-233. {2016. 03} (SCI, 2015 IF = 0.473) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    150. Li-Hong Wang, Chih-Yang Lin, Shih-Chia Liu, Guan-Ting Liu, Yen-Ling Chen, Jih-Jung Chen, Chia-Han Chan, Ting-Yi Lin, Chi-Kuan Chen, Guo-Hong Xu, Shiou-Sheng Chen, Chih-Hsin Tang*, Shih-Wei Wang*. CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells. Oncotarget 2016, 7 (24), 36896-36908. {2016. 05} (SCI, 2015 IF = 5.008)
    151. Wan Mohd Nuzul Hakimi Wan Salleh, Farediah Ahmad*, Heng Yen Khong, Razauden Mohamed Zulkifli, Jih-Jung Chen, Lutfun Nahar, Jean Duplex Wansi, Satyajit Dey Sarker. Beilschglabrines A and B: Two new bioactive phenanthrene alkaloids from the stem bark of Beilschmiedia glabra. Phytochemistry Letters 2016, 16, 192-196. {2016. 06} (SCI, 2015 IF = 1.353)
    152. Chun-Lin Chen, Deng-Chyang Wu, Min-Yun Liu, Ming-Wei Lin, Hung-Tu Huang, Yaw-Bin Huang, Li-Chai Chen, Yu-Yu Chen, Jih-Jung Chen, Pei-Hua Yang, Yu-Chen Kao, Pei-Yu Chen. Cholest-4-en-3-one attenuates TGF-β responsiveness by inducing TGF-β receptors degradation in Mv1Lu cells and colorectal adenocarcinoma cells. Journal of Receptors and Signal Transduction 2016, 36, 1-11. DOI: 10.1080/10799893.2016.1203944 {2016. 07} (SCI, 2015 IF = 1.782)
    153. Ming-Jen Cheng*, Ming-Der Wu, Yen-Chen Cheng, Jih-Jung Chen*, Hing-Yuen Chan*, Yen-Lin Chen, Ih-Sheng Chen, Po-Hung Wu, Gwo-Fang Yuan. One new compound from the extract of the fungus Monascus purpureus BCRC 31499. Chemistry of Natural Compounds 2016, 52 (4), 634-636. {2016. 07} (SCI, 2015 IF = 0.473)
    154. Kai-Yu Peng, Nan-Fu Chen, Zhi-Cheng Chen, Kuan-Hao Tsui, Zhi-Hong Wen, Yin-Di Su, Yu-Chia Chang, Yu-Hsin Chen, Mei-Chin Lu, Lee-Shing Fang, Jih-Jung Chen, Tung-Ying Wu, Yang-Chang Wu*, Ping-Jyun Sung*. Cladieunicellins R and S, new eunicellins from the Formosan octocoral Cladiella tuberculosa. Tetrahedron Letters 2016, 57, 4239-4242. {2016. 08} (SCI, 2015 IF = 2.347)
    155. Chun-Lin Chen*, Yu-Chen Kao, Pei-Hua Yang, Ping-Jyun Sung, Zhi-Hong Wen, Jih-Jung Chen, Yaw-Bin Huang, and Pei-Yu Chen. A small dibromotyrosine derivative purified from Pseudoceratina sp. suppresses TGF-b responsiveness by inhibiting TGF-b type I receptor serine/threonine kinase activity. Journal of Cellular Biochemistry 2016, 117 (12), 2800-2814. {2016. 12} (SCI, 2015 IF = 3.446)
    156. Chang-Syun Yang†, Hui-Chi Huang, Sheng-Yang Wang, Ping-Jyun Sung, Guan-Jhong Huang†, Jih-Jung Chen† and Yueh-Hsiung Kuo*. New diphenol and isocoumarins from the aerial part of Lawsonia inermis and their inhibitory activities against NO production. Molecules 2016, 21, 1299; doi:10.3390/molecules21101299. {2016.09} (SCI, 2015 IF = 2.465) (†Authors have contributed equally in this manuscript.)
    157. Ta-Yuan Whuang, Wen-Cheng Tsai, Nan-Fu Chen, Zhi-Cheng Chen, Kuan-Hao Tsui, Zhi-Hong Wen, Yin-Di Su, Yu-Chia Chang, Yu-Hsin Chen, Mei-Chin Lu, Lee-Shing Fang, Jih-Jung Chen, Tung-Ying Wu, Yang-Chang Wu, Ping-Jyun Sung. Columnaristerol A, a novel 19-norsterol from the Formosan octocoral Nephthea columnaris. Bioorganic & Medicinal Chemistry Letters 2016, 26, 4966-4969. {2016.09} (SCI, 2015 IF = 2.486)
    158. Chi-I Chang, Chien-Chih Chen, Sheng-Yang Wang, Che-Yi Chao, Louis Kuoping Chao, Jih-Jung Chen, Horng-Huey Ko, Cheng-Chi Chen, and Yueh-Hsiung Kuo*. Three new abietane-type diterpenes from the bark of Cryptomeria japonica. Helvetica Chimica Acta 2016, 99 (9), 710-715. {2016.09} (SCI, 2015 IF = 1.087)
    159. Jih-Jung Chen*, Tung-Han Tsai, Hsiang-Ruei Liao, Li-Chai Chen, Yueh-Hsiung Kuo, Ping-Jyun Sung, Chun-Lin Chen and Chun-Sheng Wei. New sesquiterpenoids and anti-platelet aggregation constituents from the rhizomes of Curcuma zedoaria. Molecules 2016, 21, 1385; doi:10.3390/molecules21101385 {2016.10} (SCI, 2015 IF = 2.465) (Ranking in Chemistry, Organic: 24/59 = 40.6 %)
    160. Dong-Zong Hung, Ni Tien, Cheng-Li Lin, Ying-Ray Lee, Charles-C. N. Wang, Jih-Jung Chen, Yun-Ping Lim*. Increased risk of chronic osteomyelitis after hip replacement: a retrospective population-based cohort study in an Asian population. European Journal of Clinical Microbiology & Infectious Diseases 2016, doi: 10.1007/s10096-016-2836-0 {2016.11} (SCI, 2015 IF = 2.857)
    161. Dong-Zong Hung, Cheng-Li Lin, Yi-Wen Li, Yen-Ning Lin, Ying-Ray Lee, Charles-C. N. Wang, Jih-Jung Chen, Yun-Ping Lim*. Association between antiepileptic drugs and hepatocellular carcinoma in patients with epilepsy: a population-based case-control study. Brain and Behavior 2016, 6: 1-7. e00554, doi: 10.1002/brb3.554. {2016.11} (SCI, 2015 IF = 2.128)
    162. Wu-Fu Chen, Yu-Chia Chang, Yuh-Wen Chiu, Lee-Shing Fang, Yu-Hsin Chen, Yin-Di Su, Bo-Rong Pengd, Mei-Chin Lud, Jih-Jung Chen, Zhi-Hong Wen, Yang-Chang Wu*, Ping-Jyun Sung*. Oxytoxin-2, An Algal-Derived Molecule from a Cultured Mollusc Volvatella vigourouxi. Natural Product Communications 2016, 11 (12), 1783-1784. {2016.12} (SCI, 2015 IF = 0.884)
    163. Jih-Jung Chen*, Hsiang-Ruei Liao, Keh-Shaw Chen, Chih-Wen Shu, Ping-Jyun Sung, Yun-Ping Lim, Tai-Chi Wang, and Wen-Lung Kuo. A new 2H-pyran-2-one derivative and anti-inflammatory constituents from Alpinia zerumbet. Chemistry of Natural Compounds 2016, 51 (x), in press. {2015. xx} (SCI, 2015 IF = 0.473) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    164. Jih-Jung Chen*, Wen-Lung Kuo, Hsiang-Ruei Liao, Yueh-Hsiung Kuo, Ih-Sheng Chen, Chih-Wen Shu, Ping-Jyun Sung, Yun-Ping Lim, Tai-Chi Wang, Rong Xu. A new benzenoid and anti-inflammatory constituent from Capparis acutifolia. Chemistry of Natural Compounds 2016, in press. (SCI, 2015 IF = 0.473) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    165. Li-Chai Chen, Zhi-Hong Wen, Ping-Jyun Sung, Chih-Wen Shu, Wen-Lung Kuo, Pei-Yu Chen, and Jih-Jung Chen*. New labdane-type diterpenoid and cytotoxic constituents from Hedychium coronarium. Chemistry of Natural Compounds 2016, in press. (SCI, 2015 IF = 0.473) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    166. Jih-Jung Chen*, Ming-Chi Hung, Hsiang-Ruei Liao, Yueh-Hsiung Kuo, Chih-Wen Shu, Ping-Jyun Sung, Yun-Ping Lim, Wen-Lung Kuo, Lin-Yang Cheng, Sin-Ling Wang, and Jui-Jen Wu. A new xanthone and anti-inflammatory constituents from Garcinia subelliptica. Chemistry of Natural Compounds 2016, in press. (SCI, 2015 IF = 0.473) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    167. Ming-Jen Cheng*, Ming-Der Wu, Hing-Yuen Chan*, Yen-Chen Cheng*, Jih-Jung Chen*, Ih-Sheng Chen, Yung-Shun Su, and Gwo-Fang Yuan. New Metabolite isolated from the fungus Monascus pilosus. Chemistry of Natural Compounds 2016, in press. (SCI, 2015 IF = 0.473) (Ranking in Chemistry, Organic: 53/57 = 93.0 %)
    168. Jih-Jung Chen*, Ming-Jen Cheng, Chih-Wen Shu, Ping-Jyun Sung, Yun-Ping Lim, Lin-Yang Cheng, and Sin-Ling Wang. A new chalcone and antioxidant constituents from Glycyrrhiza glabra. Chemistry of Natural Compounds 2016, in press. (SCI, 2015 IF = 0.473)
    169. Tsang-Hsiung Lin, Chih-Chi Cheng, Hsing-Hao Su, Nan-Chieh Huang, Jih-Jung Chen, Hong-Yo Kang, Tsung-Hsien Chang*. Lipopolysaccharide attenuates induction of pro-allergic cytokines, thymic stromal lymphopoietin and interleukin 33, in respiratory epithelial cells stimulated with polyI:C and human parechovirus. Frontiers in Immunology 2016, 7: 440. doi: 10.3389/fimmu.2016.00440 {2016.10} (SCI, 2015 IF = 5.695)
    170. Chi-I Chang, Chien-Chih Chen, Sheng-Yang Wang, Hsun-Shuo Chang, Louis Kuoping Chao, Jih-Jung Chen1, Cheng-Chi Chenk1, Yueh-Hsiung Kuol*. Three new abietane-type diterpenes from the bark of Cryptomeria japonica. Phytochemistry Letters 2017, 19, 46-49. (1These authors contributed equally to this article.) (SCI, 2015 IF = 1.353)
    171. Lin-Yang Cheng, Hsiang-Ruei Liao, Li-Chai Chen, Shih-Wei Wang, Yueh-Hsiung Kuo, Mei-Ing Chung*, Jih-Jung Chen*. Naphthofuranone derivatives and other constituents from Pachira aquatica with inhibitory activity on superoxide anion generation by neutrophils. Fitoterapia 2017, 117, 16-21. {2017.03} (SCI, 2015 IF = 2.408) (Ranking in Pharmacology & Pharmacy: 124/255 = 48.62 %)
    172. Ming-Hsien Chien, Tzong-Huei Lee, Wei-Jiunn Lee, Yen-Hsiu Yeh, Tsai-Kun Li, Po-Chuan Wang, Jih-Jung Chen, Jyh-Ming Chow, Yung-Wei Lin, Michael Hsiao, Shih-Wei Wang*, Kuo-Tai Hua*. Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts. Cancer Letters 2016, 388, 249-261. {2017.03} (SCI, 2015 IF = 5.992) (Ranking in Oncology: 23/213 = 10.79 %) (DOI: 10.1016/j.canlet.2016.12.002)
林宥欣教授
Lin, Yu-Hsin
藥學系|教授2017年8月迄今
(02)28267000#7932
Office:守仁大樓707室
中華民國國立清華大學|化學工程學所博士2002-2006
中華民國逢甲大學|化學工程學所碩士2000-2002
中華民國逢甲大學|化學工程學所學士1996-2000
  • 專長
    藥物傳遞應用、奈米藥物載體、奈米生物醫學、生物醫學工程
  • 現職
    • 國立陽明大學|藥學系|教授2017年8月迄今教授2017年8月迄今
  • 經歷
    • 中國醫藥大學|生物科技學系|教授2015年9月至2017年7月
    • 中國醫藥大學|生物科技學系|副教授2011年2月至2015年8月
    • 美國德州達拉斯|西南醫學中心|訪問助理教授2014年8月至2015年1月
    • 中國醫藥大學|教務處課務組|組長2011年8月至2013年7月
    • 中國醫藥大學|生物科技學系|助理教授2007年8月至2011年1月
    • 國立清華大學|化學工程學系|博士後研究員2006年8月至2007年7月
  • 論文
    1. Lin YH, Lu KY, Tseng CL, Wu JY, Chen CH, Mi F*. Development of genipin-crosslinked fucoidan/chitosan-N-arginine nanogels for antibiotic delivery to treat Helicobacter pylori infection. Nanomedicine [Epub ahead of print]. (SCI) IF:4.889; BIOTECHNOLOGY & APPLIED MICROBIOLOGY; Ranking: 18/161 (first author)
    2. Lin YH*, Lin JH, Hong YS. Development of chitosan/poly-γ-glutamic acid/pluronic/curcumin nanoparticles in chitosan dressings for wound regeneration. Journal of Biomedical Materials Research Part B: Applied Biomaterials (2017) January 105(1):81-90. (SCI) IF:2.881; ENGINEERING, BIOMEDICAL; Ranking: 17/76 (first author & corresponding author)
    3. Huang WY, Lin JN, Hsieh JT, Chou SC, Lai CH, Yun EJ, Lo UG, Pong RC, Lin JH, Lin YH*. Nanoparticle targeting CD44-positive cancer cells for site-specific drug delivery in prostate cancer therapy. ACS Applied Materials and Interfaces (2016) November 16;8(45):30722-30734. (SCI) IF:7.145; MATERIALS SCIENCE, MULTIDISCIPLINARY; Ranking: 25/271 (corresponding author)
    4. Lin YH*, Lin JH, Li TS, Wang SH, Yao CH, Chung WY, Ko TH. Dressing with epigallocatechin gallate-nanoparticles for wound regeneration. Wound Repair and Regeneration (2016) March 24(2):287-301. (SCI) IF:2.628; DERMATOLOGY; Ranking: 12/61 (first author & corresponding author)
    5. Lin YH*, Hsu WS, Chung WY, Ko TH, Lin JH. Silver-based wound dressings reduce bacterial burden and promote wound healing. International Wound Journal (2016) August 3(4):505-511. IF:2.594; DRMATOLOGY: Ranking: 13/61 (first author & corresponding author)
    6. Lai CK, Chen YA, Lin CJ, Lin HJ, Kao MC, Huang MZ, Lin YH, Ni CC, Chen CJ, Lo UG, Lin LC, Lin YH, Hsieh JT, Lai CH*. Molecular mechanisms and potential clinical applications of Campylobacter jejuni cytolethal distending toxin. Frontiers in cellular and infection microbiology (2016) February 6(9):1-8. (SCI) IF:5.218; MICROBIOLOGY Ranking: 18/123
    7. Lin YH*, Chen ZR, Lai CH, Hsieh CH, Feng CL. Active targeted nanoparticles for oral administration of gastric cancer therapy. Biomacromolecules (2015) September 16(9):3021-3032. (SCI) IF:5.583; CHEMISTRY, ORGANIC; Ranking: 6/59 (first author & corresponding author)
    8. Lai CK, Su JC, Lin YH, Chang CS, Feng CL, Lin HJ, Teseng GC, Liu HH, Hsieh JT, Su HL, Lai CH*. Involvement of cholesterol in Campylobacter jejuni cytolethal distending toxin-induced pathogenesis. Future Microbiology (2015) April 10(4):489-501. (SCI) IF:3.637; MICROBIOLOGY Ranking: 35/123
    9. Lin YH*, Lin JH, Chou SC, Chang SJ, Chung CC, Chen YS, Chang CH. Berberine-loaded targeted nanoparticles as specific Helicobacter pylori eradication therapy: in vitro and in vivo study. Nanomedicine (2015) January 10(1):57-71. (SCI) IF:4.889; BIOTECHNOLOGY & APPLIED MICROBIOLOGY; Ranking: 18/161 (first author & corresponding author)
    10. Lin YH*, Feng CL, Lai CH, Lin JH, Chen HY. Preparation of epigallocatechin gallate-loaded nanoparticles and characterization of their inhibitory effects on Helicobacter pylori growth in vitro and in vivo. Science and Technology of Advanced Materials (2014) August. 15(4):045006. (SCI) IF:3.443; MATERIALS SCIENCE, MULTIDISCIPLINARY; Ranking: 54/271 (first author & corresponding author)
    11. Lin YH*, Hsu WS, Chung WY, Ko TH, co-Lin JH. Evaluation of various silver-containing dressing on infected excision wound healing study. Journal of Materials Science: Materials and Medicine (2014) May 25(5):1375-1386. (SCI) IF:2.272; ENGINEERING, BIOMEDICAL; Ranking: 27/76 (first author & corresponding author)
    12. Lai CK, Lu YL, Hsieh JT, Tsai SC, Feng CL, Tsai YS, Tsai PC, Su HL, Lin YH*, Lai CH*. Development of chitosan/heparin nanoparticle-encapsulated cytolethal distending toxin for gastric cancer therapy. Nanomedicine (2014) May 9(6):803-817. (SCI) IF:4.889; BIOTECHNOLOGY & APPLIED MICROBIOLOGY; Ranking: 18/161 (co-corresponding author)
    13. Lin YH*, Tsai YS, Lai CH, Lee CH, He ZS, Teseng GC. Genipin-cross-linked fucose-chitosan/heparin nanoparticles for the eradication of Helicobacter pylori. Biomaterials (2013) June 34(18):4466-4479. (SCI) IF:8.387; MATERIALS SCIENCE, BIOMATERIALS; Ranking: 1/33 (first author & corresponding author)
    14. Lee CH, Lin YH, Hsieh JL, Chen MC, Kuo WL. A polymer coating applied to salmonella prevents the binding of salmonella-specific antibodies. International Journal of Cancer (2013) February 132(3):717–725. IF:5.531; ONCOLOGY; Ranking: 29/213.
    15. Lin YH*, Lin JH, Wang SH, Ko TH, Teseng GC. Evaluation of silver-containing activated carbon fiber for wound healing study: in vitro and in vivo. Journal of Biomedical Materials Research Part B: Applied Biomaterials (2012) November 100(8):2288-2296. (SCI) IF:2.881; ENGINEERING, BIOMEDICAL; Ranking: 17/76 (first author & corresponding author)
    16. Lin YH*, Chiou SF, Lai CH, Tsai SC, Chou CW, Peng SF, He ZS. Formulation and evaluation of water-in-oil amoxicillin-loaded nanoemulsions using for Helicobacter pylori eradication. Process Biochemistry (2012) October 47(10)1469-1478. (SCI) IF:2.529; ENGINEERING, CHEMICAL; Ranking: 21/133 (first author & corresponding author)
    17. Huang WY, Yeh CL, Lin JH, Yang JS, Ko TH, Lin YH*. Development of fibroblast culture in three-dimensional activated carbon fiber-based scaffold for wound healing. Journal of Materials Science: Materials and Medicine (2012) June 23(6):1465–1478. (SCI) IF:2.272; ENGINEERING, BIOMEDICAL; Ranking: 27/76 (corresponding author)
    18. Liao WC, Lin YH, Chang TM, Huang WY*. Identification of two licorice species, Glycyrrhiza uralensis and Glycyrrhiza glabra, based on separation and identification of their bioactive components. Food Chemistry (2012) June 132(4):2188–2193. (SCI) IF:4.052; FOOD SCIENCE & TECHNOLOGY; Ranking: 7/125 (co-first author)
    19. Tsai SC, Huang WW, Huang CH, Lu CC, Chiang JH, Peng SF, Chung JG, Lin YH, Hsu YM, Amagaya S, Yang JS*. ERK-modulated intrinsic signaling and G2/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells. International Journal of Oncology (2012) December 41(6):2065-2072. (SCI) IF:3.018; ONCOLOGY; Ranking: 100/213
    20. Rao YK, Lien HM, Lin YH, Hsu YM, Yeh CT, Chen CC, Lai CH*, Tzeng YM. Antibacterial activities of Anisomeles indica constituents and their inhibition effect on Helicobacter pylori-induced inflammation in human gastric epithelial cells. Food Chemistry (2012) May 132(2):780–787. (SCI) IF:4.052; DOOD SCIENCE & TECHNOLOGY; Ranking: 7/125
    21. Yu DY, Tang CH, Chang CH, MC Maa, SH Fang, Hsu YM, Lin YH, Lin CJ, Lee WC, Lin HJ, Lee CH, Lai CH*. Helicobacter pylori attenuates lipopolysaccharide-induced nitric oxide production by murine macrophages. Innate Immunity (2012) June 18(3):406–417. (SCI) IF:2.206; MEDICINE, RESEARCH & EXPERIMENTAL; Ranking: 41/93
    22. Lin CD, Lai CK, Lin YH, Hsieh JT, Sing YT, Chang YC,Chen KC, Wang WC, Su HL, Lai CH*. Cholesterol depletion reduces entry of Campylobacter jejuni cytolethal distending toxin and attenuates intoxication of host cells. Infection and immunity 2011;79:3563-3575. (SCI) 3.603 INFECTIOUS DISEASES; Ranking: 20/83.
    23. Chen NG, Lu CC, Lin YH, Chen WC, Lai CH, Ho YJ, Chung JG, Lin TH, Lin YC, Yang JS*. Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: Roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways. Oncology Reports 2011;24:939-947. (SCI) 2.486 ONCOLOGY; Ranking: 130/213
    24. Huang SM, Cheung CW, Chang CS, Tang CH, Liu JF, Lin YH, Chen JH, Ko SH, Wong KL*, Yu DY*. Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer. Journal of Cellular Biochemistry 2011;112:643-652. (SCI) 3.446 CELL BIOLOGY; Ranking: 86/187
    25. Lin YH*, Lin JH, Peng SF, Yeh CL, Chen WC, Chang TL, Liu MJ, Lai CH. Multifunctional gentamicin supplementation of poly(r-glutamic acid)-based hydrogels for wound dressing application. Journal of Applied Polymer Science 2011;120:1057-1068. (SCI) (first author & Corresponding author) 1.866 POLYMER SCIENCE ; Ranking: 35/85
    26. Chang CH, Huang WY, Lai CH, Hsu YM, Yao YH, Chen TY, Wu JY, Peng SF, Lin YH*. Development of novel nanoparticles shelled with heparin for berberine delivery to treat Helicobacter pylori. Acta Biomaterialia 2011;7:593-603. (SCI) (Corresponding author) 6.008 ENGINEERING, BIOMEDICAL; Ranking: 3/76
    27. Chang CH, Lin YH*, Yeh CL, Chen YC, Chiou SF, Hsu YM, Chen YS, Wang CC. Nanoparticles Incorporated in pH-Sensitive Hydrogels as Amoxicillin Delivery for Eradication of Helicobacter pylori. Biomacromolecules 2010;11:133-142. (SCI) (Corresponding author) 5.583 POLYMER SCIENCE; Ranking: 5/85
    28. Lin JH*, Ko TH, Kuo WS, Lin YH, Huang CC, Chen WC. Effect of various hydrophobic concentration and base weights of gas diffusion layer for proton exchange membrane fuel cells. Fuel Cells 2010;1:118-123. (SCI) 1.769 ENERGY & FUELS; Ranking: 47/88
    29. Chen MC, Wong HS, Lin KJ, Chen HL, Wey SP, Sonaje Kiran, Lin YH, Chu CY, Sung HW*. The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin. Biomaterials 2009;30:6629-6637. (SCI) 8.387 MATERIALS SCIENCE, BIOMATERIALS; Ranking: 1/33
    30. Lin JH*, Ko TH, Lin YH, Pan CK. Various treated conditions to prepare porous activated carbon fiber for application in supercapacitor electrodes. Energy&Fules 2009;23:4668-4677. (SCI) 2.790 ENERGY & FUELS; Ranking: 32/83
    31. Sonaje Kiran, Lin YH, Juang JH, Wey SP, Chen CT, Sung HW*. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery. Biomaterials 2009;30:2329-2339. (SCI) 8.387 MATERIALS SCIENCE, BIOMATERIALS; Ranking: 1/33
    32. Lin YH*, Chang CH, Wu YS, Hsu YM, Chiou SF, Chen YJ. Development of pH-responsive chitosan/heparin nanoparticles for stomach-specific anti-Helicobacter pylori therapy. Biomaterials 2009;30:3332-3342. (SCI) (first author & Corresponding author) 8.387 MATERIALS SCIENCE, BIOMATERIALS; Ranking: 1/33
    33. Lin YH, Sonaje Kiran, Lin KM, Juang JH, Mi FL, Yang HW, Sung HW*. Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs. Journal of Controlled Release 2008;132:141-149. (SCI) (1st author) 7.441 PHARMACOLOGY & PHARMACY; Ranking: 9/253.
    34. Mi FL, Wu YY, Lin YH, Sonaje Kiran, Ho YC, Chen CT, Juang JH, Sung HW*. Oral delivery of peptide drugs using nanoparticles self-assembled by poly(γ-glutamic acid) and a chitosan derivative functionalized by trimethylation. Bioconjugate Chemistry 2008;19:1248-1255. (SCI) 4.500 CHEMISTRY, ORGANIC; Ranking: 10/59
    35. Lin YH, Mi FL, Chen CT, Chang WC, Peng SF, Liang HF, Sung HW*. Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery. Biomacromolecules 2007;8:146-152. (SCI) (first author) 5.583 POLYMER SCIENCE; Ranking: 5/85
    36. Lin YH, Chen CT, Liang HF, Kulkarni Anandrao R, Lee PW, Chen CH, Sung HW*. Novel nanoparticles for oral insulin delivery via the paracellular pathway. Nanotechnology 2007;18:1-11. (SCI) (first author) 3.573 PHYSICS, APPLIED ; Ranking: 24/145
    37. Mi FL, Liang HF, Wu YC, Lin YH, Yang TF, Sung HW*. pH-Sensitive behaviors of two component hydrogels composed of N,O-carboxymethyl chitosan and alginate. Journal of Biomaterials Science-Polymer Edition 2005;16:1333-1345. (SCI) 1.733 POLYMER SCIENCE; Ranking: 38/85
    38. Kulkarni AR, Lin YH, Liang HF, Chang WC, Hsiao WW, Sung HW*. A novel method for the preparation of nanoaggregates of methoxy-polyethylene-glycol linked chitosan. Journal of Nanoscience and Nanotechnology 2006;6:2867-2873. (SCI) 1.338 MATERIALS SCIENCE, MULTIDISCIPLINARY; Ranking: 168/271
    39. Lin YH, Chung CK, Chen CT, Liang HF, Chen SC, Sung HW*. Preparation of nanoparticles composed of chitosan/poly-γ-glutamic acid and evaluation of their permeability through Caco-2 cells. Biomacromolecules 2005;6:1104-1112. (SCI) (first author) 5.583 POLYMER SCIENCE; Ranking: 5/85
    40. Lin YH, Liang HF, Chung CK, Chen MC, Sung HW*. Physically crosslinked alginate/N,O-Carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs. Biomaterials 2005;26: 2105-2113. (SCI) (first author) 8.387 MATERIALS SCIENCE, BIOMATERIALS; Ranking: 1/33
    41. Liang HF, Hong MH, Ho RM, Chung CK, Lin YH, Chen CH, Sung HW*. Novel method using a temperature-sensitive polymer (methylcellulose) to thermally gel aqueous alginate as a pH-sensitive hydrogel. Biomacromolecules 2004;5:1917-1925. 5.583 POLYMER SCIENCE; Ranking: 5/85
    42. Chen SC, Wu YC, Mi FL, Lin YH, Yu LC, Sung HW*. A Novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate crosslinked by genipin for protein drug delivery. Journal of Controlled Release 2004;96:285-300. (SCI) 7.441 PHARMACOLOGY & PHARMACY; Ranking: 9/253
    43. Huang SW, Lin YH, Wang WC, Kuo BY, Chou CP*. Effect of pH on high-temperature production of bacterial penicillin acylase in Escherichia coli. Biotechnology Progress 2002;18:668-671. (SCI) 2.167 FOOD SCIENCE & TECHNOLOGY; Ranking: 33/124
    44. Lin YH, Hsiao HC, Chou CP*. Strain improvement to Enhance the production of recombinant penicillin acylase in high-cell-density Escherichia coli cultures. Biotechnology Progress 2002;18:1458-1461. (SCI) (first author) 2.167 FOOD SCIENCE & TECHNOLOGY; Ranking: 33/124
    45. Lin YH, Fang WL, Lin WJ, Huang SW, Chou CP*. Improving production of penicillin acylase in Escherichia coli via efficient DegP-mediated processing of precursors in periplasm. Process Biochemistry 2001;37;23-30. (SCI) (first author) 2.529 ENGINEERING, CHEMICAL; Ranking: 35/135
胡德民 副教授
Hu, Teh-Min
藥學系|副教授2016年8月迄今
(02)28267000#7984
美國俄亥俄州立大學|藥劑學博士1997-2002
國防醫學院|藥劑學碩士1991-1993
國防醫學院|藥學士|藥師 1985-1989
  • 專長
    奈米製藥、藥動/藥效學與生物藥劑學、定量系統藥理學
  • 現職
    • 國立陽明大學|藥學系|副教授2016年8月迄今
  • 經歷
    • 國防醫學院|藥學系|副教授 2011年2月至2016年8月
      Western Institutional Review Board (WIRB)|International Fellow 2005年7月至2005年12月
    • 國防醫學院|藥學系|助理教授 2003年6月至2011年2月
    • 國防醫學院|藥學系|助教 1989年8月至1997年8月
  • 論文
    1. Chi-Kang Lin, Meng-Yi Bai, Teh-Min Hu, Yu-Chi Wang, Tai-Kuang Chao, Shao-Ju Weng, and Hung-Cheng Lai. Preclinical evaluation of a nanoformulated antihelminthic, niclosamide, in ovarian cancer. Oncotarget 7(8):8993-9006, 2016
    2. Shih-Jiuan Chiu, Chien-Yu Lin, Hung-Chang Chou, and Teh-Min Hu*. Silica ouzo effect: Amphiphilic drugs facilitate nanoprecipitation of polycondensed mercaptosilanes. Langmuir 32: 211–220, 2016
    3. Meng-Ren Wang, Shih-Jiuan Chiu, Hung-Chang Chou and Teh-Min Hu*. An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug. Chemical Communications 51:15649-15652, 2015
    4. Hung-Chang Chou, Shih-Jiuan Chiu, and Teh-Min Hu*. LbL Assembly of albumin on nitric oxide-releasing silica nanoparticles using suramin, a polyanion drug, as an interlayer linker. Biomacromolecules 16(8):2288–2295, 2015
    5. Wei-Lin Chang, Kang-Jen Peng, Teh-Min Hu, Shih-Jiuan Chiu, Ying-Ling Liu. Nitric oxide-releasing S-nitrosothiol-modified silica/chitosan core–shell nanoparticles. Polymer 57 (28):70–76, 2015
    6. Teh-Min Hu*, Shih-Jiuan Chiu, Yu-Ming Hsu. Nitroxidative chemistry interferes with fluorescent probe chemistry: Implications for nitric oxide detection using 2,3-diaminonaphthalene. Biochem Biophys Res Commun 451 (2):196–201, 2014
    7. Shih-Jiuan Chiu*, Su-Yuan Wang, Hung-Chang Chou, Ying-Ling Liu, and Teh-Min Hu*. Versatile synthesis of thiol- and amine-bifunctionalized silica nanoparticles based on the ouzo Effect. Langmuir 30 (26):7676–7686, 2014
    8. Hung-Chang Chou,Shih-Jiuan Chiu,Ying-Ling Liu, and Teh-Min Hu*. Direct formation of S-Nitroso silica nanoparticles from a single silica source. Langmuir 30:812-822, 2014
    9. Ssu-Han Chen, Shih-Jiuan Chiu and Teh-Min Hu*, Superoxide dismutase as a novel macromolecular nitric oxide carrier: preparation and characterization. Int J Mol Sci 13(11): 13985-14001, 2012
    10. Shan-Chu Ho, and Shih-Jiuan Chiu, and Teh-Min Hu*. Comparative kinetics of thiol oxidation in two distinct free-radical generating systems: SIN-1 vs. AAPH. Free Radical Research 46(10): 1190–1200, 2012
    11. Teh-Min Hu*, Shan-Chu Ho. Kinetics of redox interaction between cytochrome c and thiols. J Med Sci. 31(3):109-115, 2011
    12. Teh-Min Hu*, Shan-Chu Ho. Similarity and dissimilarity of thiols as anti-nitrosative agents in the nitric oxide–superoxide system. Biochem Biophys Res Commun 404:785-789, 2011
    13. interaction network. J Clin Pharm Ther 36:135-143, 2011
    14. Teh-Min Hu* and Yu-Jen Chen. Nitrosation-modulating effect of ascorbate in a model dynamic system of coexisting nitric oxide and superoxide. Free Rad Res 44(5):552-562, 2010
    15. Teh-Min Hu* and Shih-Jiuan Chiu. Prediction of human drug clearance using a single-species, fixed-exponent allometric approach. J Med Sci 29(6): 331-339, 2009
    16. William L Hayton, Teh-Min Hu. Allometric Scaling. in Gad S (ed) Preclinical Development Handbook, John Wiley & Sons, Inc., Hoboken, NJ, 2008
    17. Teh-Min Hu*, William L. Hayton, and Susan R. Mallery. Kinetic modeling of nitric-oxide-associated reaction network. Pharm Res 23(8):1702-1711, 2006頁97-107。
    18. Teh-Min Hu* and Ta-Chuan Chou, The kinetics of thiol-mediated decomposition of S-nitrosothiols. AAPS Journal, 8(3):E485-E492, article 57, 2006.
許銘能助理教授
Shiu, Ming-Neng
藥學系|助理教授 2016年8月1日迄今
(02)28267000#7985
中華民國國立臺灣大學|流行病學博士1998-2002
中華民國國立臺灣大學|公共衛生碩士1996-1998
中華民國國立陽明醫學院|學士後醫學士1985-1990
中華民國國立臺灣大學|藥學士1979-1983
  • 專長
    癌症篩檢、社區醫學、預防醫學、流行病學、藥事法規、衛生行政
  • 現職
    • 國立陽明大學|藥學系|助理教授2016年8月迄今
  • 經歷
    • 衛生福利部|常務次長2013年7月至2016年6月
    • 行政院衛生署|副署長 2013年5月至2013年7月
    • 行政院衛生署|醫事處|處長 2012年8月至2013年5月
    • 行政院衛生署|企劃處|處長 2011年11月至2012年8月
    • 行政院衛生署|食品藥物管理局|副局長 2011年1月至2011年11月
    • 國立台灣大學|流行病學與預防醫學研究所|兼任助理教授 2006年9月至今
    • 台北縣政府|衛生局|局長 2003年9月至2010年12月
    • 基隆市|衛生局|副局長 2000年2月至2003年4月
    • 行政院衛生署|保健處|科長 1994年3月至2000年1月
    • 台北縣衛生局|貢寮鄉衛生所|主任兼醫師 1993年1月至1994年2月
    • 國立台灣大學醫學院附設醫院|家庭醫學科|住院醫師 1990年7月至1992年12月
  • 論文
    1. Chen CC, Wang SL, Wu MT, Wang YH, Huang PC, Chen BH, Sun CW, Ho CK, Shih YC, Shiu MN, Pan WH, Chen ML, Lee CC, Hsiung CA. Exposure Estimation for Risk Assessment of the Phthalate Incident in Taiwan. PLoS One. 2016 Mar 9;11(3):e0151070. doi: 10.1371/journal.pone.0151070. eCollection 2016.
    2. Chang SC, Shiu MN, Chen HT, Ng YY, Lin LC, Wu SC. Evaluation of care quality for disabled older patients living at home and in institutions. J Clin Nurs. 2015 Dec;24(23-24):3469-80. doi: 10.1111/jocn.12946. Epub 2015 Sep 1.
    3. Chang YH, Shiu MN, Hsiung CA. Planning and evaluation in health workforce development: projection for the pharmacy workforce in Taiwan. J Formos Med Assoc. 2013 Dec;112(12):733-4. doi: 10.1016/j.jfma.2013.07.016. Epub 2013 Sep 4.
    4. Huang HL, Shyu YI, Huang HL, Chen ST, Li HJ, Shiu MN, Pong MC. Factors associated with dementia care practices among community health nurses: results of a postal survey. Int J Nurs Stud. 2013 Sep;50(9):1219-28. doi: 10.1016/j.ijnurstu.2012.02.016. Epub 2012 Mar 18.
    5. Ling-Jie Chen, Yu-Hsin Lo, Ming-Neng Shiu, Shu-Jen Lee, Wen-Chun Lin, Ying-Hwa Lee, Yunn-Fang Ho: Implementation of Information Technology in Primary Care Pharmacy. Formosan J Med 2010;14:114-23
東雅惠助理教授
Dong, Yaa-Hui
藥學系|助理教授2016年8月迄今
(02)28267000#7986
中華民國國立臺灣大學|流行病學與預防醫學博士2008-2012
中華民國國立臺灣大學|藥學碩士(臨床藥學)1999-2001
中華民國國立臺灣大學|藥學士 1994-1998
  • 專長
    藥物流行病學、臨床藥學
  • 現職
    • 國立陽明大學|藥學系|助理教授2016年8月迄今
  • 經歷
    • 美國|哈佛醫學院暨布里格姆及婦女醫院|博士後研究員2014年至2016年8月
    • 國立臺灣大學|健康資料研究中心|博士後研究員 2012年至2013年
    • 國泰綜合醫院|藥劑科|藥師 2003年至2008年
    • 中華景康藥學基金會|研究助理 2003年
    • 和信治癌中心醫院|藥劑科|藥師 2002年至2003年
    • 國立臺灣大學|臨床藥學研究所|助教 2001年至2002年
    • 馬偕紀念醫院|藥劑科|藥師 1998年至1999年
  • 論文
    1. Dong YH, Chang CH*, Wu LC, Lai MS. Use of cardioselective β-blockers and overall death and cardiovascular outcomes in patients with COPD: a population-based cohort study. Eur J Clin Pharmacol. 2016 Jul 22. [Epub ahead of print]
    2. Dong YH, Chang CH*, Gagne JJ, Hsu CL, Lai MS. Comparative cardiovascular and cerebrovascular safety of bronchodilators in patients with chronic obstructive pulmonary disease: a population-based cohort study. Pharmacotherapy. 2016;36:26-37.
    3. Dong YH#, Hsu CL#, Li YY, Chang CH*, Lai MS. Bronchodilators use in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2015;10:1769-79.
    4. Lo Y, Shen LJ, Chen WH, Dong YH, Wu FL. Risk factors of ifosfamide-related encephalopathy in adult patients with cancer: A retrospective analysis. J Formos Med Assoc. 2015 Aug 21. [Epub ahead of print]
    5. Weng TC#, Chang CH#, Dong YH, Chang YC, Chuang LM*. Anemia and related nutrient deficiencies after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis. BMJ Open. 2015;5:e006964.
    6. Dong YH, Chang CH*, Mahler DA. Response: secondary outcomes and Peto OR in meta-analysis. Chest 2014;146:e212-3.
    7. Chen GL#, Hsiao FY#, Dong YH, Shen LJ*, Wu FL*. Statins and the risk of liver injury: a population-based case-control study. Pharmacoepidemiol Drug Saf 2014;23:719-25.
    8. Dong YH#, Chang CH#, Wu FL, Shen LJ, Calverley PMA, Löfdahl CG, Lai MS*, Mahler DA. Use of inhaled corticosteroids in patients with chronic obstructive pulmonary disease and the risk of tuberculosis and influenza: a systematic review and meta-analysis of randomized controlled trials. Chest 2014;145:1286-97.
    9. Dong YH, Lin JW, Wu LC, Chen CY*, Chang CH*, Chen KY, Lai MS. Examining the association between statins and lung cancer incidence in patients with type 2 diabetes mellitus. J Formos Med Assoc 2014;113:940-8.
    10. Dong YH, Lin HH, Shau WY, Wu YC, Chang CH*, Lai MS*. Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomized controlled trials. Thorax 2013;68:48-56.
    11. Dong YH, Chang CH, Shau WY, Kuo RN, Lai MS*, Chan KA*. Development and validation of a pharmacy-based comorbidity measure in a population-based automated healthcare database. Pharmacotherapy 2013;33:126-36.
    12. Lascelles BD*, Dong YH, Marcellin-Little DJ, Thomson A, Wheeler S, Correa M. Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats. BMC Vet Res 2012;8:10.
    13. Kuo RN, Dong YH, Liu JP, Chang CH, Shau WY, Lai MS*. Predicting healthcare utilization using a pharmacy-based metric with the WHO's Anatomic Therapeutic Chemical algorithm. Med Care 2011;49:1031-9.
    14. 張意宜、江村煌、東雅惠*。某區域醫院病人使用含碘顯影劑產生立即性不良反應之研究。臺灣臨床藥學雜誌 2013,21卷2期。頁1-10。
    15. 東雅惠、黃婉翠、林惜燕*。介紹日本醫院藥局藥事服務-以九州大學附設醫院藥劑部為例。藥學雜誌 2009,25卷3期。頁72-4。
    16. 東雅惠、林惜燕*。談日本病院藥劑管理指導-以九州大學附設病院藥劑部為例。藥學雜誌 2007,23卷4期。頁12-5。
    17. 東雅惠、黃婉翠、方信智、吳淑英、黃政華、徐志育、林惜燕*。某醫學中心門診病人上呼吸道感染抗生素使用之改善措施及其影響。臺灣家庭醫學研究 2007,5卷3期。頁97-107。
蘇溶真助理教授
Su, Jung-Chen
(02)28267000#5760
國立陽明大學生物藥學所|博士2010-2014
高雄醫學大學醫藥暨應用化學所|碩士2009-2010
高雄醫學大學醫藥暨應用化學系|學士2005-2009
  • 專長
    新藥開發、轉譯醫學研究
  • 現職
    • 國立陽明大學|藥學系|助理教授2016年迄今
  • 經歷
    • 台大醫學院|醫學檢驗暨生物技術學系|博士後研究員 2014年12月至2016年7月
    • 財團法人德澤醫學研究基金會|博士後研究員 2014年10月至2014年11月
    • 台大醫學院|腫瘤醫學部|博士後研究員 2014年9月
  • 論文
    1. Su JC, Mar AC, Wu SH, Tai WT, Chu PY, Wu CY, Tseng LM, Lee TC, Chen KF, Liu CY, Chiu HC, Shiau CW. Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis. Sci Rep. 2016; 6:28888. (First author)
    2. Mukherjee N, Lu Y, Almeida A, Lambert K, Shiau CW, Su JC, Luo Y, Fujita M, Robinson WA, Robinson SE, Norris DA, Shellman YG. Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells. Oncotarget. 2016 Apr 12.
    3. Chang HC, Huang YT, Chen CS, Chen YW, Huang YT, Su JC, Teng LJ, Shiau CW, Chiu HC. In vitro and in vivo activity of a novel sorafenib derivative SC5005 against MRSA. J Antimicrob Chemother. 2016; 71(2):449-59.
    4. Su JC, Chang JH, Huang JW, Chen PP, Chen KF, Tseng PH, Shiau CW. Copper-obatoclax derivative complexes mediate DNA cleavage and exhibit anti-cancer effects in hepatocellular carcinoma. Chem Biol Interact. 2015; 228:108-13. (First author)
    5. Su JC, Chiang HC, Tseng PH, Tai WT, Hsu CY, Li YS, Huang JW, Ko CH, Lin MW, Chu PY, Liu CY, Chen KF, Shiau CW. RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells. Carcinogenesis. 2014; 35(12):2807-14. (First author)
    6. Tai WT, Chu PY, Shiau CW, Chen YL, Li YS, Hung MH, Chen LJ, Chen PL, Su JC, Lin PY, Yu HC, Chen KF. STAT3 mediates regorafenib-induced apoptosis in hepatocellular carcinoma. Clin Cancer Res. 2014; 20(22):5768-76.
    7. Liu CY, Hung MH, Wang DS, Chu PY, Su JC, Teng TH, Huang CT, Chao TT, Wang CY, Shiau CW, Tseng LM, Chen KF. Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells. Breast Cancer Res. 2014; 16(5):431.
    8. Su JC, Tseng PH, Wu SH, Hsu CY, Tai WT, Li YS, Chen IT, Liu CY, Chen KF, Shiau CW. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma. Neoplasia. 2014; 16(7):595-605. (First author)
    9. Su JC, Tseng PH, Hsu CY, Tai WT, Huang JW, Ko CH, Lin MW, Liu CY, Chen KF, Shiau CW. RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells. Oncotarget. 2014; 5(13):4909-19. (First author)
    10. Liu CY, Su JC, Ni MH, Tseng LM, Chu PY, Wang DS, Tai WT, Kao YP, Hung MH, Shiau CW, Chen KF. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. Breast Cancer Res Treat. 2014; 146(1):71-84. (First author)
    11. Liu CY, Tseng LM, Su JC, Chang KC, Chu PY, Tai WT, Shiau CW, Chen KF. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013; 15(4):R63.
    12. Su JC, Chen KF, Chen WL, Liu CY, Huang JW, Tai WT, Chen PJ, Kim I, Shiau CW. Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists. Eur J Med Chem. 2012; 56:127-33. (First author)
    13. Chen KF, Pao KC, Su JC, Chou YC, Liu CY, Chen HJ, Huang JW, Kim I, Shiau CW. Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity. Bioorg Med Chem. 2012; 20(20):6144-53.
    14. Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW. A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation. Cancer Lett. 2012; 321(1):27-35. (First author)
    15. Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells. Clin Exp Pharmacol Physiol. 2010; 636(1-3):52-8. (First author)
    16. Chien CM, Lin KL, Su JC, Chuang PW, Tseng CH, Chen YL, Chang LS, Lin SR. Naphtho[1,2-b]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: involvement of EGF receptor/PI3K/Akt signaling pathway. Eur J Pharmacol. 2010; 636(1-3):52-8.
    17. Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR. Naphtho[1,2-b]furan-4,5-dione disrupts Janus kinase-2 and induces apoptosis in breast cancer MDA-MB-231 cells. Toxicol In Vitro. 2010; 24(4):1158-67.
    18. Lin KL, Su JC, Chien CM, Chuang PW, Chang LS, Lin SR. Down-regulation of the JAK2/PI3K-mediated signaling activation is involved in Taiwan cobra cardiotoxin III-induced apoptosis of human breast MDA-MB-231. Toxicon. 2010; 55(7):1263-73.
    19. Su JC, Lin KL, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR. Naphtho[1,2-b]furan-4,5-dione inactivates EGFR and PI3K/Akt signaling pathways in human lung adenocarcinoma A549 cells. Life Sci. 2010; 86(5-6):207-13. (First author)
    20. Chien CM, Lin KL, Su JC, Chang LS, Lin SR. Inactivation of epidermal growth factor receptor and downstream pathways in oral squamous cell carcinoma Ca9-22 cells by cardiotoxin III from Naja naja atra. J Nat Prod. 2009; 72(10):1735-40.
    21. 2 Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR. Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation. Toxicol In Vitro. 2010; 24(1):61-70.
    22. Su JC, Lin KL, Chien CM, Lu CM, Chen YL, Chang LS, Lin SR. Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation. Life Sci. 2009; 85(13-14):505-16. (First author)
    23. Yang SH, Chien CM, Su JC, Chen YL, Chang LS, Lin SR. Novel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cells. J Biochem Mol Toxicol. 2008;22(6):396-404.
姜紹青講師
Chiang, Shao-Chin
(02)28970011 #1801、(02)28267000 #5962
美國Creighton University|Doctor of Pharmacy 1993-1997
中華民國國立臺灣大學|藥學士1986-1990
  • 專長
    癌症藥物治療學、安寧緩和藥物治療學、藥師執業教育、危害性藥品處理
  • 現職
    • 國立陽明大學|藥學系|講師2016年迄今
    • 臺北市和信治癌中心醫院|藥劑科|副主任 2012年迄今
  • 經歷
    • 臺北市和信治癌中心醫院|藥劑科|組長2005年至2012年
    • 臺北市和信治癌中心醫院|藥劑科|副組長 2001年至2005年月
    • 臺北市和信治癌中心醫院|藥劑科|臨床藥師 2000年至2001年
    • 美國威斯康辛大學附設醫院|癌症專科住院藥師 1999年1月至1999年12月
    • 美國威斯康辛大學附設醫院|通科住院藥師 1997年7月至1998年6月
  • 論文
    1. Wen TJ, Wen YW, Chien CR, Chiang SC, Hsu WW, Shen LJ, Hsiao FY. Cost-effectiveness of granulocyte colony-stimulating factor prophylaxis in chemotherapy-induced febrile neutropenia among breast cancer and Non-Hod handling for anti-neoplastic hazardous drugs: a multidisciplinary consensus guidelines in Taiwan. The Journal of Oncology Nursing 2015;15:1-54.
    2. Lin WT, Wen YW, Chien CR, Gau CS, Chiang SC, Hsiao FY.Suboptimal duration of granulocyte colony-stimulating factor use and chemotherapy-induced neutropenia in women diagnosed with breast cancer. Clin Ther. 2014;36(9):1287-94.
    3. Chang LL, Chiang SC, Chiu CF, et al. Safe handling for anti-neoplastic hazardous drugs: a multidisciplinary consensus guidelines in Taiwan. The Journal of Oncology Nursing 2013;13:1-54.
    4. Chang LL, Schneider SM, Chiang SC, Horng CF. Implementing an evidence-based risk assessment tool to predict chemotherapy-induced neutropenia in women with breast cancer. Cancer Nursing 2013;36(3):198-205.
    5. Chang LL, Liu TW, Deng ST, Chiu CF, Chiang SC, Chang MC, Chang CW. Guideline for safe chemotherapy administration: a multidisciplinary consensus guideline in Taiwan. The Journal of Oncology Nursing 2012;12(2):5-21.
    6. TSHP Task force of Taiwan guideline on handling hazardous drugs. 2010 Taiwan guideline on handling hazardous drugs. Formosa J Clin Pharm 2010;18: S1-63. [Corresponding author]