羅文良 老師(Wen-Liang Lo)
個人簡歷

 

學歷:

陽明大學牙醫學系 學士

陽明大學牙醫學系 博士

PhD, Department of dentistry, School of Dentistry, National Yang-Ming University, 2010

經歷:

台北榮總住院醫師

台北榮總牙科部總醫師

台北榮總牙科部口腔顎面外科主治醫師

密西根大學口腔顎面外科研究

專長口腔顎面外科學口腔腫瘤學組織工程學蛋白質藥物學

單位:台北榮民總醫院口腔醫學部口腔顎面外科

職稱:主治醫師
聯絡電話(02) 2875-7572 ext 725
傳真電話(02) 2826-4053
電子郵件:wllo@vghtpe.gov.tw
研究方向

1. Oral and Maxillofacial Surgery: implant surgery and cases report

2. Oral Cancersoral cancer stem cells

3. Tissue Engineering: Ex-vivo produced oral mucosal equivalent

4. Protein Engineering: “programmed self-destruction” ribotoxin

研究計畫(五年內)
  1. Lo WL, et al: Designing and engineering protein drug based on a new concept of programmed self-destructing which induced apoptosis of oral cancer cells. Taipei Veterans General Hospital, VGH-99C1-195, 2010
  2. Lo WL, et al: Development of protein drug of target therapy against the oral cancer stem cells, Yen Tjing Ling Medical Foundation, CI-98-18, 2009
  3. Lo WL, et al: Conditioned production of bioactive insulin from human oral keratinocytes and ex-vivo produced oral mucosal equivalent, VGH-97F-004, 2009
  4. Lo WL, et al: Establishment of oral keratinocyte cell bank and fabrication of ex-vivo produced oral mucosal graft, Yen Tjing Ling Medical Foundation, CI-97-18, 2008
  5. Lo WL, et al: Real-time monitoring of the ex-vivo produced oral mucosal equivalent with non-invasive Raman spectroscopy, VGH-97-01-24A, 2008
得獎紀錄

台北榮總94年「臨床教學績優醫師獎」

台北榮總98年「臨床教學績優醫師獎」

中華民國口腔顎面外科學會98年最佳論文獎

中華民國口腔顎面外科學會99年最佳論文獎

著作

International papers

  1. Cheng-Chia Yu, Wen-Liang Lo, Yi-Wei Chen, Pin-I Huang, Han-Shui Hsu, Ling-Ming Tsen, Shou-Yen Kao, Charn-Jung Chang, and Shih Hwa Chiou. Bmi-1 Regulates Snail Expression and Promotes Metastasis Ability in Head and Neck Squamous Cancer-derived ALDH1 positive Cells. J Oncol. 2010 Aug 15 accpted
  2. Wen-Liang Lo, Jian-Yun Lai, Stephen E. Feinberg, Kenji Izumi, Shou-Yen Kao, Che-Shoa Chang, Alan Lin, Huihua Kenny Chiang. Raman spectroscopy monitoring of the cellular activities of a tissue-engineered ex-vivo produced oral mucosal equivalent . J Raman Spec. 2010 Mar 15 accepted (SCI) (2009 JCR: IF 3.147; Spectroscopy 7/39)
  3. Yu-Chih Chen, Charn-Jung Chang, Han-Shui Hsu, Yi-Wei Chen, Lung-Kuo Tai, Ling-Ming Tseng, Guang-Yuh Chiou, Shih-Ching Chang, Shou-Yen Kao, Shih-Hwa Chiou, Wen-Liang Lo. Inhibition of Tumorigenicity and Enhancement of Radiochemosensitivity in Head and Neck Squamous Cancer-derived ALDH1-positive Cells by Knockdown of Bmi-1. Oral Oncol. 2009 Dec 29. 46:158-165. (SCI) (2009 JCR: IF 3.123; Dentistry, oral surgery & medicine 3/64; Oncology 64/165)
  4. Yu-Chih Chen, Yi-Wei Chen, Han-Shui Hsu, Ling-Ming Tseng, Pin-I Huang, Kai-Hsi Lu, Lung-Kuo Tai, Ming-Chi Yung, Shih-Ching Chang, Hung-Hai Ku, Shih-Hwa Chiou, Wen-Liang Lo. Aldehyde Dehydrogenase 1 Is a Putative Marker for Cancer Stem Cells in Head and Neck Squamous Cancer. Biochem Biophys Res Commun. 2009 Jul 31;385(3):307-13. (SCI) (2009 JCR: IF 2.548; BIOCHEMISTRY & MOLECULAR BIOLOGY 146/283; Biophysics 40/74)
  5. Chen YW, Yu EH, Wu TH, Lo WL, Li WY, Kao SY. Histopathological factors affecting nodal metastasis in tongue cancer: analysis of 94 patients in Taiwan. Int J Oral Maxillofac Surg. 2008 Oct;37(10):912-6. (SCI) (2009 JCR: IF 1.444; Dentistry, oral surgery & medicine 31/64; Surgery 71/166)
  6. Chen YW, Tu HF, Wu TH, Lo WL, Chang CS, Chang KW. Sarcomas and sarcomatoid tumor after radiotherapy of oral squamous cell carcinoma: analysis of 4 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jan;105(1):65-71. (SCI) (2009 JCR: IF 1.499; Dentistry, oral surgery & medicine 29/64)
  7. Chu CH, Tu TY, Li AF, Lo WL, Yen CC: Pathology quiz case: Metastatic osteosarcoma of the external auditory canal. Archives of Otolaryngology Head & Neck Surgery 132(1): 109-110, 2006 (SCI). (2009 JCR: IF 1.918; Otorhinolaryngology 8/36; Surgery 53/166)
  8. Yu EH, Lui MT, Chou SJ, Wang SJ, Hung KF, Lo WL, Chang CS, Wu CH, Kao SY: Comparison of Positron Emission Tomography and Computed Tomography for the Detection of Cervical Lymph Node Metastases of Oral Squamous Cell Carcinoma. Asian Journal of Oral & Maxillofacial Surgery 18: 109-115, 2006.

Domestic papers

  1. Wu HT, Lai HC, Huang CK, Lui MT, Kao SY, Lo WL: Pediatric Sialolithiasis a case report and literature review. Taiwan Journal of Oral and Maxillofacial Surgery 21(1): 69-75, 2010.
研究成果圖


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