鄭詠馨 Cheng, Yung-Hsin

兼任助理教授 Assistant professor

電話:886-2-27093600 ext. 3824

E-mailyunghsin@ym.edu.twchengyunghsin@gmail.com

Education

l   2008/09-2012/06 Ph.D., Biomedical Engineering, National Taiwan University, Taiwan

l   2006/09-2008/06 M.S., Biomedical Engineering, National Taiwan University, Taiwan

l   2002/09-2006/06 BEng., Department of Material Science and Engineering, National Taiwan University of Science and Technology, Taiwan

Awards

 

l   2015 Best Poster Paper Award. Paper Competition of Taipei City Hospital, Taipei, Taiwan

l   2014 Young Investigator Award. World Congress on Preventive and Regenerative Medicine (7th WCPRM)

l   2011 Graduate Students Study Abroad Program, National Science Council, Taipei, Taiwan

l   2009 Excellent Research Award. Annual Meeting of Formosa Association of Regenerative Medicine, Taipei, Taiwan

Professional Experiences

l   2014/08-present Assistant Investigator, Department of Education and Research, Taipei City Hospital, Taipei, Taiwan

l   2014/08-present Adjunct Assistant Professor, Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan

l   2014/01-2014/08 Adjunct Assistant Investigator, Department of Education and Research, Taipei City Hospital, Taipei, Taiwan

l   2013/08-2014/08 Project Assistant Professor, Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan

l   2012/07-2013/07 Postdoctrol Research Fellow, Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan

l   2012/03-2012/05 Visiting Researcher, Department of Bioengineering, University of Washington, Seattle, USA

l   2011/08 Visiting Student, Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel

l   2011/06 Scientific Co-chair, Student and Young Investigator Section (SYIS) Activity, TEMIS EU 2011, Granada, Spain

Research Interests

l   Biomaterials

l   Drug delivery system

l   Tissue engineering

 

Publications:

1.     Cheng YH, Lin FH, Wang CY, Hsiao CY, Chen HC, Kuo HY, Tsai TF, Chiou SH. Recovery of oxidative stress-induced damage in cisd2-deficient cardiomyocytes by sustained release of ferulic acid from injectable hydrogel. Biomaterials. 2016; 103:207-18. (SCI, IF: 8.387, Rank: 2/76, ENGINEERING, BIOMEDICAL)

2.     Chan SH, Hung CH, Shih JY, Chu PM, Cheng YH, Tsai YJ, Lin HC, Tsai KL. Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure. Oncotarget 2016 (SCI, IF: 5.009, Rank: 36/213, ONCOLOGY)

3.     Cheng YH, Tsai TH, Jhan YY, Chiu AW, Tsai KL, CS Chien, Chiou SH, Liu CJ. Thermosensitive chitosan-based hydrogel as a topical ocular drug delivery system of latanoprost for glaucoma treatment. Carbohydrate Polymers 2016; 144:390-9. (SCI, IF: 4.219, Rank: 5/71, CHEMISTRY, APPLIED)

4.     Tsai CY, Woung LC, Yen JC, Tseng PC, Chiou SH, Sung YJ, Liu KT, Cheng YH*. Thermosensitive chitosan-based hydrogels for sustained release of ferulic acid on corneal wound healing. Carbohydrate Polymers 2016; 135:308-15. (SCI, IF: 4.219, Rank: 5/71, CHEMISTRY, APPLIED)

5.     Tsai KL, Chang YL, Huang PH, Cheng YH, Liu DH, Chen HY, Kao CL. Ginkgo biloba extract inhibits oxidized low-density lipoprotein (oxLDL)-induced matrix metalloproteinase activation by the modulation of the lectin-like oxLDL receptor 1-regulated signaling pathway in human umbilical vein endothelial cells. J Vasc Surg. 2016; 63:204-15 (SCI, IF: 3.454, Rank: 21/199, SURGERY)

6.     Chan SH, Chu PM, Kao CL, Cheng YH, Hung CH, Tsai KL. Oleic acid activates MMPs up-regulation through SIRT1/PPAR-γ inhibition: a probable linkage between obesity and coronary arterial disease.  The Journal of Biochemistry 2016 (SCI, IF: 2.397, Rank: 171/289, BIOCHEMISTRY & MOLECULAR BIOLOGY) (Accepted, in press)

7.     Kuo WT, Huang JY, Chen MH, Chen CY, Shyong YJ, Yen KC, Sun YJ, Ke CJ, Cheng YH, Lin FH. Development of gelatin nanoparticles conjugated with phytohemagglutinin erythroagglutinating loaded with gemcitabine for inducing apoptosis in non-small cell lung cancer cells. Journal of Materials Chemistry B 2016; 4:2444-54 (SCI, IF: 4.872, Rank: 4/33, MATERIALS SCIENCE, BIOMATERIALS)

8.     Tsai IL, Hsu CC, Hung KH, Chang CW, Cheng YH*. Mini-review: Applications of biomaterials in corneal wound healing. Journal of the Chinese Medical Association 2015; 78:212-17. (SCI, IF: 1.013, Rank: 87/151, MEDICINE, GENERAL & INTERNAL)

9.     Cheng YH, Hung KH, Tsai TH, Lee CJ, Ku RY, Chiu AW, Chiou SH, Liu CJ. Sustained delivery of latanoprost by thermosensitive chitosan-gelatin-based hydrogel for controlling ocular hypertension. Acta Biomaterialia 2014; 10: 4360-66 (SCI, IF: 6.008, Rank: 3/76, ENGINEERING, BIOMEDICAL)

10.  Tsai KL, Huang PH, Kao CL, Leu SB, Cheng YH, Liao YW, et al. Aspirin attenuates Vinorelbine-induced endothelial inflammation via modulating SIRT1/AMPK axis. Biochemical Pharmacology 2014; 88:189-200. (SCI, IF: 5.091, Rank: 18/253, PHARMACOLOGY & PHARMACY)

11.  Chang YC, Chang WC, Hung KH, Yang DM, Cheng YH, Liao YW, Woung LC, Tsai CY, Hsu CC, Lin TC, Liu JH, Chiou SH, Peng CH, Chen SJ. The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress. Frontiers in Aging Neuroscience 2014; 6:191. (SCI, IF: 4.348, Rank: 6/49, GERIATRICS & GERONTOLOGY)

12.  Cheng YH, Yang SH, Liu CC, Gefen A, Lin FH. Thermosensitive hydrogel made of ferulic acid-gelatin and chitosan glycerophosphate. Carbohydrate Polymers 2013; 92:1512-9. (SCI, IF: 4.219, Rank: 5/71, CHEMISTRY, APPLIED)

13.  Cheng YH, Yang SH, Lin FH. Thermosensitive chitosan-gelatin-glycerol phosphate hydrogel as a controlled release system of ferulic acid for nucleus pulposus regeneration. Biomaterials. 2011; 32:6953-61. (SCI, IF: 8.387, Rank: 2/76, ENGINEERING, BIOMEDICAL)

14.  Cheng YH, Yang SH, Yang KC, Chen MP, Lin FH. The effects of ferulic acid on nucleus pulposus cells under hydrogen peroxide-induced oxidative stress. Process Biochemistry 2011; 46:1670-7. (SCI, IF:2.529, Rank: 35/135, ENGINEERING, CHEMICAL)

15.  Cheng YH, Yang SH, Su WY, Chen YC, Yang KC, Cheng WT, Wu SC, Lin FH. Thermosensitive chitosan-gelatin-glycerol phosphate hydrogels as a cell carrier for nucleus pulposus regeneration: an in-vitro study. Tissue Engineering Part A 2010; 16:695-703. (SCI, IF: 3.892, Rank: 30/161, BIOTECHNOLOGY & APPLIED MICROBIOLOGY)

16.  Chen MP, Yang SH, Chou CH, Yang KC, Wu CC, Cheng YH, Lin FH. The chondroprotective effects of ferulic acid on hydrogen peroxide-stimulated chondrocytes: inhibition of hydrogen peroxide-induced pro-inflammatory cytokines and metalloproteinase gene expression at the mRNA level. Inflammation Research 2010; 59:587-95. (SCI, IF: 2.557, Rank: 86/150, IMMUNOLOGY)

17.  Yang KC, Wu CC, Cheng YH, Kuo TF, Lin FH. Chitosan/gelatin hydrogel prolonged the function of insulinoma/agarose microspheres in vivo during xenogenic transplantation. Transplantation Proceedings 2008; 40:3623-6. (SCI, IF: 0.867, Rank: 149/199, SURGERY)

18.  Yang KC, Wu CC, Lin FH, Qi Z, Kuo TF, Cheng YH, Chen MP, Sumi S. Chitosan/gelatin hydrogel as immunoisolative matrix for injectable bioartificial pancreas. Xenotransplantation 2008; 15:407-16. (SCI, IF: 3.789, Rank: 27/124, MEDICINE, RESEARCH & EXPERIMENTAL)