image002.pngCurriculum Vitae - Shuen-Iu Hung (洪舜郁)

 

Personal Information

Name: Shuen-Iu Hung

Address: No. 155, Sec. 2, Li-Nong Street, Institute of Pharmacology, National Yang-Ming University, Taipei 112, Taiwan

Tel: (02)28267201

Fax: (02)28264372

Email: sihung@ym.edu.tw

 

 

Education and Positions

Ph.D., Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan (September 1994~April 2002)

Post-Doctoral Fellow, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan (July 2002~June 2003)

Assistant Director, National Genotyping Center, Academia Sinica, Taipei, Taiwan (July 2003~June 2006)

Adjunct Assistant Researcher, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan (August 2009~July 2012)

Assistant Professor, Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan (2006-2010)

Associate Professor, Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan (2010-present)

 

 

Honors and Awards

2002:陽明大學優秀博士論文獎

2004: Outstanding Post-Doctoral Research, Award of 2004 annual meeting of The Association of Chinese Geneticists in America (ACGA)

2005: Distinguished Postdoctoral Scholar of Academia Sinica

2005: HGM2005 Award for Young Scientist, 10th Annual Meeting of The Human Genome Organization (HUGO)

2007: 陽明大學教師優秀論文獎

2007~2008, 2012: 陽明大學優良教師

2009: 國科會傑出技術移轉貢獻獎

2011~2014: 陽明大學教師學術卓越獎勵

2010: Taiwan Outstanding Female Scientist-Junior Investigator 2010, Award of Wu Chien-Shiung Education Foundation (2010)第三屆台灣傑出女科學家新秀獎(吳健雄博士基金會)

2012: Dr. Wu, Da-You Research Award 2012, National Science Council (2012) 行政院國科會吳大猷先生紀念獎

 

 

Research Interests

Pharmacogenomics, pathogenesis and molecular mechanism of adverse drug reactions.

 

 

Papers/Publications

1.       Chung WH, Chang WC, Lee YS, Wu YY, Yang CH, Ho HC, Chen MJ, Lin JY, Hui RC, Ho JC, Wu WM, Chen TJ, Wu T, Wu YR, Hsih MS, Tu PH, Chang CN, Hsu CN, Wu TL, Choon SE, Hsu CK, Chen DY, Liu CS, Lin CY, Kaniwa N, Saito Y, Takahashi Y, Nakamura R, Azukizawa H, Shi Y, Wang TH, Chuang SS, Tsai SF, Chang CJ, Chang YS, Hung SI*; Taiwan Severe Cutaneous Adverse Reaction Consortium; Japan Pharmacogenomics Data Science Consortium. Genetic variants associated with phenytoin-related severe cutaneous adverse reactions. JAMA. 2014 Aug 6;312(5):525-34. (*Correspondence) (SCI) (Impact factor: 30)

2.       Chung WH, Chang WC, Stocker SL, Juo CG, Graham GG, Lee MH, Williams KM, Tian YC, Juan KC, Jan Wu YJ, Yang CH, Chang CJ, Lin YJ, Day RO, Hung SI*. Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin. Annals of the Rheumatic Diseases 2014 Aug 12. pii: annrheumdis-2014-205577. (*Correspondence) (SCI) (Impact factor: 9.27)

3.       Pan RY, Wu YC, Chung WH, Hung SI*. HLA and TCR Recognition of Medications in Severe Cutaneous Adverse Reactions. Current Immunology Reviews 2014, in press.

4.       Yeh CN, Chung WH, Su SC, Chen YY, Cheng CT, Lin YL, Chang WC, Chung-Yee Hui R, Chiang KC, Chen TW, Jan YY, Chen CW, Chen TJ, Yang CH, Hung SI*. Fas/Fas Ligand Mediates Keratinocyte Death in Sunitinib-Induced Hand-Foot Skin Reaction. Journal of Investigative Dermatology 2014 May 6. doi: 10.1038/jid.2014.218. [Epub ahead of print] (*Correspondence) (SCI) (Impact factor: 6.37)

5.       Su SC, Chung WH, Hung SI*. Digging up the human genome: current progress in deciphering adverse drug reactions. BioMed Research International 2014;2014:824343. (*Correspondence) (SCI) (Impact factor: 2.706)

6.       Huang CC, Chung CM, Hung SI, Leu HB, Lin LY, Huang PH, Wu TC, Lin SJ, Pan WH, Chen JW. Genetic predictors of thiazide-induced serum potassium changes in nondiabetic hypertensive patients. Hypertension Research 2014 Aug;37(8):759-64 (SCI) (Impact factor: 2.936)

7.       Lin YF, Yang CH, Sindy H, Lin JY, Rosaline, Hui CY, Tsai YC, Wu TS, Huang CT, Kao KC, Hu HC, Chiu CH, Hung SI, Chung WH. Severe Cutaneous Adverse Reactions Related to Systemic Antibiotics. Clinical Infectious Diseases 2014 May;58(10):1377-85. (SCI) (Impact factor: 9.416)

8.       Genin E*, Chen DP*, Hung SI*, Sekula P, Schumacher M, Chang PY, Tsai SH, Wu TL, Bellón T, Tamouza R, Fortier C, Toubert A, Charron D, Hovnanian A, Wolkenstein P, Chung WH, Mockenhaupt M, Roujeau JC. HLA-A*31:01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis. The Pharmacogenomics Journal 2014 Jun;14(3):281-8 (*Co-first author) (SCI) (Impact factor: 5.513)

9.       Hsiao YH, Hui RC, Wu T, Chang WC, Hsih MS, Yang CH, Ho HC, Chang YG, Chen MJ, Lin JY, Chen DP, Chang PY, Wu TL, Hung SI*, Chung WH*. Genotype-phenotype association between HLA and carbamazepine-induced hypersensitivity reactions: Strength and clinical correlations. Journal of Dermatological Science 2014 Feb;73(2):101-9. (*Correspondence) (SCI) (Impact factor: 3.335)

10.    Chung WH, Shih SR, Chang CF, Lin TY, Huang YC, Chang SC, Liu MT, Ko YS, Deng MC, Liau YL, Lin LH, Chen TH, Yang CH, Ho HC, Lin JW, Lu CW, Lu CF, Hung SI*. Clinicopathologic Analysis of Coxsackievirus A6 new variant induced widespread mucocutaneous bullous reactions mimicking severe cutaneous adverse reactions. The Journal of Infectious Diseases 2013 Dec;208(12):1968-78. (*Correspondence) (SCI) (Impact factor: 5.778)

11.    Wang CW, Chung WH, Cheng YF, Ying NW, Peck K, Hung SI*. A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders. J Allergy Clin Immunol. 2013 Sep;132(3):713-722.e11. (*Correspondence) (SCI) (Impact factor: 12.047; Rank: 4.55%)

12.    Hung SI, WH Chung. HLA-B*1502 genotyping for preventing phenytoin-induced Stevens-Johnson syndrome and toxic epidermal necrolysis? NEUROLOGY 2013;80(17):1621-2. (SCI)(Impact factor: 8.25;Rank: 2.16%)

13.    Lin YT, Chang YC, Hui RC, Yang CH, Ho HC, Hung SI, Chung WH. A patch testing and cross-sensitivity study of carbamazepine-induced severe cutaneous adverse drug reactions. J Eur Acad Dermatol Venereol. 2013 Mar;27(3):356-64. (SCI) (Impact factor: 2.69).

14.    Wei CY, Chung WH, Huang HW, Chen YT, Hung SI*. Direct interaction between HLA-B and carbamazepine activates T cells in Stevens-Johnson syndrome. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2012;129(6):1562-1569 (SCI).(Impact factor: 12.047; Rank: 4.55%) (*correspondence)

15.    Huang CC, Chung CM, Leu HB, Lin TH, Hung SI, Wu TC, Huang PH, Lin SJ, Pan WH, Chen JW. Genetic variation in C-reactive protein in ethnic Chinese population in Taiwan. Eur J Clin Invest. 2013 May;43(5):449-56. (SCI)(Impact factor: 3.365; Ranking: 16.13%)

16.    Chung WH, Hung SI. Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis. JOURNAL OF DERMATOLOGICAL SCIENCE 2012;66(3):190-196 (SCI).(Impact factor: 3.520;Rank: 12.73%)

17.    Chen P, Lin JJ, Lu CS, Ong CT, Hsieh PF, Yang CC, Tai CT, Wu SL, Lu CH, Hsu YC, Yu HY, Ro LS, Lu CT, Chu CC, Tsai JJ, Su YH, Lan SH, Sung SF, Lin SY, Chuang HP, Huang LC, Chen YJ, Tsai PJ, Liao HT, Lin YH, Chen CH, Chung WH, Hung SI, Wu JY, Chang CF, Chen L, Chen YT, Shen CY. Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan. NEW ENGLAND JOURNAL OF MEDICINE 2011;364(12):1126-1133 (SCI).(Impact factor: 53.486;Rank: 0.65%)

18.    Yang CY*, Dao RL*, Lee TJ, Lu CW, Yang, CH, Hung SI*, Chung WH.. Severe cutaneous adverse reactions to antiepileptic drugs in Asians. NEUROLOGY 2011;77(23):2025-2033 (SCI).(Impact factor: 8.25;Rank: 2.16%) (*co-first author)

19.    Ko TM, Chung WH, Wei CY, Shih HY, Chen JK, Lin CH, Chen YT, Hung SI*. Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome . JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2011;128(6):1266-1276 (SCI).(Impact factor: 12.047; Rank: 4.55%) (*correspondence)

20.    Li HY, Chien Y, Chen YJ, Chen SF, Chang YL, Chiang CH, Jeng SY, Chang CM, Wang ML, Chen LK, Hung SI, Huo TI, Lee SD, Chiou SH.. Reprogramming induced pluripotent stem cells in the absence of c-Myc for differentiation into hepatocyte-like cells Biomaterials 2011 Sep;32(26):5994-6005. BIOMATERIALS 2011;32(26):5994-6005 (SCI).(Impact factor: 7.883;Rank: 2.86%)

21.    Huang CC, Chung CM, Hung SI, Leu HB, Wu TC, Huang PH, Lin SJ, Pan WH, Chen JW. Genetic variation in renin predicts the effects of thiazide diuretics. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2011;41(8):828-835 (SCI).(Impact factor: 2.736;Rank: 16.99%)

22.    Chiang CH, Chang CC, Huang HC, Chen YJ, Tsai PH, Jeng SY, Hung SI, Hsieh JH, Huang HS, Chiou SH, Lee FY, Lee SD.. Investigation of hepatoprotective activity of induced pluripotent stem cells in the mouse model of liver injury J Biomed Biotechnol. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY 2011;2011:219060 (SCI).(Impact factor: 1.23;Rank: 69.38%)

23.    Chung WH, Dao RL, Chen LK, Hung SI*. The role of genetic variants in human longevity. AGEING RESEARCH REVIEWS 2010;Suppl (1):S67-78 (SCI).(Impact factor: 9;Rank: 2.22%)(*correspondence)

24.    Lee MT, Hung SI, Wei CY, Chen YT.. Pharmacogenetics of toxic epidermal necrolysis. EXPERT OPINION ON PHARMACOTHERAPY 2010;11(13):2153-2162 (SCI).(Impact factor: 2.403;Rank: 47.62%)

25.    Chang SL, Hu S, Hung SI, Huang YL, Hsiao WC, Chung WH. A comparison of Ki-67 antigen presentation in acute generalized exanthematous pustulosis and pustular psoriasis. ARCHIVES OF DERMATOLOGICAL RESEARCH 2010;302(7):525-529 (SCI).(Impact factor: 2.011;Rank: 36.36%)

26.    Hung SI, Chung WH, Liu ZS, Chen CH, Hsih MS, Hui RCY, Chu CY, Chen YT.. Common risk allele in aromatic anti-epileptic-drugs induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. PHARMACOGENOMICS 2010;11(3):349-356 (SCI).(Impact factor: 3.876;Rank: 17.46%)

27.    Hung SI, Chung WH, Chen YT. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory (Chapter 13. Carbamazepine and its structurally-related antiepiletics) Springer, New York, 2011.

28.    Chung WH, Hung SI. Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis. Allergol Int. 2010;59(4):325-332 (OI).

29.    Lee MJ, Chang CP, Lee YH, Wu YC, Tseng HW, Tung YY, Wu MT, Chen YH, Kuo LT, Stephenson D, Hung SI, Wu JY, Chang C, Chen YT, Chern Y. Longitudinal Evaluation of an N-Ethyl-N-Nitrosourea-Created Murine Model with Normal Pressure Hydrocephalus. PLoS One 2009;4(11):7868 (OI).(Impact factor: 4.411;Rank: 13.95%)

30.    Chung WH, Hung SI, Chen YT. Genetic predisposition of life-threatening antiepileptic-induced skin reactions. Expert Opinion On Drug Safety 2009;9(1):15-21 (SCI).(Impact factor: 2.645;Rank: 39.68%)

31.    Wu YR*, Hung SI*, Chang YC, Chen ST, Lin YL, Chung WH.. Complementary mutations in seipin gene in a patient with Berardinelli-Seip congenital lipodystrophy and dystonia: phenotype variability suggests multiple roles of seipin gene. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 2009;80(10):1180-1181 (SCI).(Impact factor: 4.791;Rank: 2.13%) (co-first author)

32.    Lin SH, Liu CM, Liu YL, Shen-Jang Fann C, Hsiao PC, Wu JY, Hung SI, Chen CH, Wu HM, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Chang CC, Yang WC, Lin JJ, Chou FH, Faraone SV, Tsuang MT, Hwu HG, Chen WJ.. Clustering by neurocognition for fine mapping of the schizophrenia susceptibility loci on chromosome 6p. GENES BRAIN AND BEHAVIOR 2009;8(8):785-794 (SCI).(Impact factor: 4.061;Rank: 12.50%)

33.    Lin WL, Lin WC, Chang YC, Yang LC, Hung SI, Hong HS, Chung WH.. Intravenous immunoglobulin-induced, non-eczematous, vesiculobullous eruptions in stevens-johnson syndrome. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY 2009;10(5):339-342 (SCI).(Impact factor: 1.963;Rank: 40.00%)

34.    Wang JR, Lee ST, Juan WH, Chuang WL, Hung SI, Chung WH, Hong HS.. Indigenous leishmaniasis in Taiwan: report of a case. INTERNATIONAL JOURNAL OF DERMATOLOGY 2008;47(1):40-43 (SCI).(Impact factor: 1.265;Rank: 65.45%)

35.    Lin WL, Lin WC, Yang JY, Chang YC, Ho HC, Yang LC, Yang CH, Hung SI, Chung WH.. Fatal toxic epidermal necrolysis associated with cetuximab in a patient with colon cancer. JOURNAL OF CLINICAL ONCOLOGY 2008;26(16):2779-2780 (SCI).(Impact factor: 18.97;Rank: 2.16%)

36.    Chiou CC, Yang LC, Hung SI, Chang YC, Kuo TT, Ho HC, Hu S, Hong HS, Chung WH.. Clinicopathlogical Features and Prognosis of Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) a Study of 30 Cases in Taiwan. Journal of the European Academy of Dermatology & Venereology 2008;22(9):1044-1049 (SCI).(Impact factor: 3.309;Rank: 18.18%)

37.    Liu YL, Fann CS, Liu CM, Chen WJ, Wu JY, Hung SI, Chen CH, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Chang CC, Yang WC, Lin JJ, Chou FH, Faraone SV, Tsuang MT, Hwu HG.. RASD2, MYH9, and CACNG2 Genes at Chromosome 22q12 Associated with the Subgroup of Schizophrenia with Non-Deficit in Sustained Attention and Executive Function. BIOLOGICAL PSYCHIATRY 2008;64(9):789-796 (SCI).(Impact factor: 8.674;Rank: 3.13%)

38.    Chung WH*, Hung SI*, Yang JY, Su SC, Huang SP, Wei CY, Chin SW, Chiou CC, Chu SC, Ho HC, Yang CH, Lu CF, Wu JY, Liao YD, Chen YT.. Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. NATURE MEDICINE 2008;14(12):1343-1350 (SCI).(Impact factor: 25.43;Rank: 0.94%) (*co-first author)

39.    Liu YL, Fann CS, Liu CM, Chang CC, Yang WC, Wu JY, Hung SI, Chan HY, Chen JJ, Hsieh MH, Hwang TJ, Faraone SV, Tsuang MT, Chen WJ, Hwu HG.. HTF9C gene of 22q1121 region associates with schizophrenia having deficit-sustained attention. PSYCHIATRIC GENETICS 2007;17(6):333-338 (SCI).(Impact factor: 2.061;Rank: 64.10%)

40.    Hung SI, Chung WH, Chen YT. Genetics of severe drug hypersensitivity reactions in Han Chinese. Drug Hypersensitivity Karger, Medical and Scientific Publishers, 2007.

41.    Liu CM, Liu YL, Fann CS, Yang WC, Wu JY, Hung SI, Chen WJ, Chueh CM, Liu WM, Liu CC, Hsieh MH, Hwang TJ, Faraone SV, Tsuang MT, Hwu HG.. No association evidence between schizophrenia and dystrobrevin-binding protein 1 (DTNBP1) in Taiwanese families. SCHIZOPHRENIA RESEARCH 2007;1(1-3):391-398 (SCI).(Impact factor: 4.374;Rank: 9.09%)

42.    Yang CW, Hung SI*, Juo CG, Lin YP, Fang WH, Lu IH, Chen ST, Chen YT.. HLA-B *1502-bound peptides: Implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2007;120(4):870-877 (SCI).(Impact factor: 11.0;Rank: 4.55%) (*correspondence)

43.    Liu YL, Fann CS, Liu CM, Chang CC, Yang WC, Hung SI, Yu SL, Hwang TJ, Hsieh MH, Liu CC, Tsuang MM, Wu JY, Jou YS, Faraone SV, Tsuang MT, Chen WJ, Hwu HG.. More evidence supports the association of PPP3CC with schizophrenia. MOLECULAR PSYCHIATRY 2007;12(10):966-974 (SCI).(Impact factor: 15.47;Rank: 0.78%)

44.    Chung WH, Hung SI, Chen YT.. Human leukocyte antigens and drug hypersensitivity. Current Opinion in Allergy and Clinical Immunology 2007;7(4):317-323. (SCI).(Impact factor: 3.431;Rank: 27.27%)

45.    Huang HW, Chiang YJ, Hung SI, Li CL, Yen JJ.. An IL-7 splicing-defect lymphopenia mouse model revealed by genome-wide mutagenesis. JOURNAL OF BIOMEDICAL SCIENCE 2007;14(2):169-181 (SCI).(Impact factor: 1.962;Rank: 50.94%)

46.    Yang HC, Lin CH, Hsu CL, Hung SI, Wu JY, Pan WH, Chen YT, Fann CS.. A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. Journal of Biomedical Science 2006;13(4):489-98. (DI).(Impact factor: 1.962;Rank: 50.94%)

47.    Liu YL, Shen-Jang Fann C, Liu CM, Wu JY, Hung SI, Chan HY, Chen JJ, Lin CY, Liu SK, Hsieh MH, Hwang TJ, Ouyang WC, Chen CY, Lin JJ, Chou FH, Chueh CM, Liu WM, Tsuang MM, Faraone SV, Tsuang MT, Chen WJ, Hwu HG.. Evaluation of RGS4 as a candidate gene for schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 2006;141(4):418-20 (SCI).(Impact factor: 4.156;Rank: 17.97%)

48.    Yang HC, Lin CH, Hung SI, Fann CS.. A comparison of individual genotyping and pooled DNA analysis for polymorphism validation prior to large-scale genetic studies. ANNALS OF HUMAN GENETICS 2006;70(3):350-359 (SCI).(Impact factor: 2.604;Rank: 48.08%)

49.    Kao HJ, Cheng CF, Chen YH, Hung SI, Huang CC, Millington D, Kikuchi T, Wu JY, Chen YT.. ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit . HUMAN MOLECULAR GENETICS 2006;15(24):3569-3577 (SCI).(Impact factor: 8.058;Rank: 8.33%)

50.    Li LH, Ho SF, Chen CH, Wei CY, Wong WC, Li LY, Hung SI, Chung WH, Pan WH, Lee MT, Tsai FJ, Chang CF, Wu JY, Chen YT.. Long contiguous stretches of homozygosity in the human genome. HUMAN MUTATION 2006;27(11):1115-21. (SCI).(Impact factor: 5.956;Rank: 11.54%)

51.    Liu YL, Fann CS, Liu CM, Chen WJ, Wu JY, Hung SI, Chen CH, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Ouyang WC, Chan HY, Chen JJ, Yang WC, Lin CY, Lee SF, Hwu HG.. A single nucleotide polymorphism fine mapping study of chromosome 1q421 reveals the vulnerability genes for schizophrenia, GNPAT and DISC1: Association with impairment of sustained attention. BIOLOGICAL PSYCHIATRY 2006;1(6):554-562 (SCI).(Impact factor: 8.674;Rank: 3.13%)

52.    Chiou CC, Chung WH, Hung SI, Yang LC, Hong HS. Fulminant type 1 diabetes mellitus caused by drug hypersensitivity syndrome with human herpesvirus 6 infection. Journal of the American Academy of Dermatology 2006;54(2):S14-S17 (SCI).(Impact factor: 4.274;Rank: 7.27%)

53.    Liu YL, Fann CS, Liu CM, Chang CC, Wu JY, Hung SI, Liu SK, Hsieh MH, Hwang TJ, Chan HY, Chen JJ, Faraone SV, Tsuang MT, Chen WJ, Hwu HG.. No association of G72 and d-amino acid oxidase genes with schizophrenia. Schizophrenia research 2006;87(1-3):15-20 (SCI).(Impact factor: 4.374;Rank: 9.09%)

54.    Hung SI, Chung WH, Jee SH, Chen WC, Chang YT, Lee WR, Hu SL, Wu MT, Chen GS, Wong TW, Hsiao PF, Chen WH, Shih HY, Fang WH, Wei CY, Lou YH, Huang YL, Lin JJ, Chen YT.. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. PHARMACOGENETICS AND GENOMICS 2006;16(4):297-306. (SCI).(Impact factor: 3.865;Rank: 17.86%)

55.    Liu YL, Fann CS, Liu CM, Wu JY, Hung SI, Chan HY, Chen JJ, Pan CC, Liu SK, Hsieh MH, Hwang TJ, Ouyang WC, Chen CY, Lin JJ, Chou FH, Chueh CM, Liu WM, Tsuang MM, Faraone SV, Tsuang MT, Chen WJ, Hwu HG.. Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population. Psychiatric Genetics 2006;16(1):39-41. (SCI).(Impact factor: 2.061;Rank: 64.10%)

56.    Lin HF, Liu YL, Liu CM, Hung SI, Hwu HG, Chen WJ.. Neuregulin 1 gene and variations in perceptual aberration of schizotypal personality in adolescents. Psychological Medicine 2005;35(11):1589-98. (SCI).(Impact factor: 5.2;Rank: 4.81%)

57.    Hung SI, Chung WH, Liou LB, Chu CC, Lin M, Huang HP, Lin YL, Lan JL, Yang LC, Hong HS, Chen MJ, Lai PC, Wu MS, Chu CY, Wang KH, Chen CH, Fann CS, Wu JY, Chen YT.. HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proceedings of the national academy of sciences of the United States of America 2005;102(11):4134-4139. (SCI).(Impact factor: 9.771;Rank: 5.08%)

58.    Hung SI, Chung WH, Chen YT.. HLA-B genotyping to detect carbamazepine-induced Stevens-Johnson syndrome: implications for personalizing medicine. Personalized Medicine 2005;2(3):225-237.(Impact factor: 1.51; Rank: 60%)

59.    Hwang HW, Chen JJ, Lin YJ, Shieh RC, Lee MT, Hung SI, Wu JY, Chen YT, Niu DM, Hwang BT.. R1193Q of SCN5A, a Brugada and long QT mutation, is a common polymorphism in Han Chinese. Journal of Medical Genetics 2005;42(2):e7 (SCI).(Impact factor: 7.037;Rank: 10.26%)

60.    Hwu WL, Yang CF, Fann CS, Chen CL, Tsai TF, Chien YH, Chiang SC, Chen CH, Hung SI, Wu JY, Chen YT.. Mapping of psoriasis to 17q terminus. Journal of Medical Genetics 2005;42(2):152-158 (SCI).(Impact factor: 7.037;Rank: 10.26%)

61.    Chung WH, Hung SI, Hong HS, Hsih MS, Yang LC, Ho HC, Wu JY, Chen YT.. Medical genetics: a marker for Stevens-Johnson syndrome. Nature 2004;428(6982):486 (SCI).(Impact factor: 36.104;Rank: 1.69%)

62.    Hong HS, Chung WH, Hung SI, Chen MJ, Lee SH, Yang LC. Clinical association of anti-golgi autoantibodies and their autoantigens. Scandinavian Journal of Immunology 2004;59(1):79-87. (SCI).(Impact factor: 1.935;Rank: 76.12%)

63.    Hu S, Chung WH, Hung SI, Ho HC, Wang ZW, Chen CH, Lu SC, Kuo TT, Hong HS.. Detection of Sporothrix schenckii in clinical samples by a nested PCR assay. Journal of Clinical Microbiology 2003;41(4):1414-1418. (SCI).(Impact factor: 4.22;Rank: 18.69%)

64.    Chung WH, Chang YC, Yang LJ, Hung SI, Wong WR, Lin JY, Chan HL.. Clinicopathologic features of skin reactions to temporary tattoos and analysis of possible causes. Archives of Dermatology 2002;138(1):88-92. (SCI).(Impact factor: 4.231;Rank: 9.09%)

65.    Hung SI, Chang AC, Kato I, Chang NC. Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation. Journal of Leukocyte Biology 2002;72(1):72-82. (SCI).(Impact factor: 4.626;Rank: 17.91%)

66.    Sun YJ, Chang NC, Hung SI, Chang AC, Chou CC, Hsiao CD.. The crystal structure of a novel mammalian lectin, Ym1, suggests a saccharide binding site. Journal of Biological Chemistry 2001;276(20):17507-17514. (SCI).(Impact factor: 5.328;Rank: 17.48%)

67.    Chang NC, Hung SI, Hwa KY, Kato I, Chen JE, Liu CH, Chang AC.. A macrophage protein, Ym1, transiently expressed during inflammation is a novel mammalian lectin. Journal of Biological Chemistry 2001;276(20):17497-17506

 

 

Books/Chapters

1.       Wu YC, Chung WH, Hung SI*. (September 2014) Genetics and Genomics of Human Longevity. In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0024643 (*correspondence)

2.       Wang CW, Chung WH, Hung SI*. Chronic inflammation: Causes, treatment options and role in diseases (Chapter VII. Chronic Inflammation of Psoriasis.) page 113-130, Editors: Chang WC, Chang WC. Nova Science Publishers, Inc., New York, 2013. ISBN:978-1-62808-095-7(*correspondence)

3.       Hung SI, Chung WH, Chen YT. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory (Chapter 13. Carbamazepine and its structurally-related antiepiletics) Springer, New York, 2011. Publication Date: February 3, 2011, 1607612828 ISBN-13: 978-1607612827

4.       Chen P, Hung SI, Chen YT. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory (Chapter 14. Allopurinol) Springer, New York, 2011. Publication Date: February 3, 2011, 1607612828 ISBN-13: 978-1607612827

5.       Hung SI, Chung WH, Chen YT. Genetics of severe drug hypersensitivity reactions in Han Chinese. Drug Hypersensitivity. Pichler WJ (Ed) Karger, Medical and Scientific Publishers, Basel, 2007. ISBN 978–3–8055–8269–8