陳肇文 教授

Jaw-Wen Chen Professor

 

 

Jaw-Wen Chen ProfessorProfessor

 

地址: 臺北榮民總醫院內科部心臟內科

 

E-mail: jwchen@vghtpe.gov.tw

 

 

Educational Attainment:

Doctor of Medicine:
(medical school)

Kaohsiung Medical University School of Medicine,
Kaohsiung, Taiwan, Republic of China

1977 - 1984

Post-doctoral Research Fellowship:
(vascular medicine & biology)

Stanford University School of Medicine,
Folk Cardiovascular Research Center,
Stanford, California, USA

1997 - 1998

 

Hospital Appointments:

Rotating internship:

Mackay Memorial Hospital,
Taipei, Republic of China

1983 - 1984

Residency:

Department of Medicine,
Taipei Veterans General Hospital, Republic of China

1986 - 1989

Fellowship and Chief Residency:

Division of Cardiology, Department of Medicine,
Taipei Veterans General Hospital, Republic of China

1990 - 1991

Clinical Research Fellowship:

Division of Cardiology, Department of Medicine,
Taipei Veterans General Hospital, Republic of China

1991 - 1993

Attending Physician:

Division of Cardiology, Department of Medicine,
Taipei Veterans General Hospital, Republic of China

1993 - present

Principle Investigator:

Department of Medical Research and Education,
Taipei Veterans General Hospital, Republic of China

2009 - present

 

Academic Appointments:

Clinical Lecture:

National Yang-Ming University School of Medicine,
and National Defense Medical College,
Taipei, Taiwan, Republic of China

1991 - 1998

Clinical Assistant Professor:

National Defense Medical College,
Taipei, Taiwan, Republic of China

1998 - 2003

Assistant Professor:

Faculty of Medicine,
National Yang-Ming University School of Medicine,
Taipei, Taiwan, Republic of China

1998 - 2003

Clinical Associate Professor:

National Defense Medical College,
Taipei, Taiwan, Republic of China

2003 - 2006

Associate Professor:

Faculty of Medicine,
National Yang-Ming University School of Medicine,
Taipei, Taiwan, Republic of China

2003 - 2006

Professor:

Faculty of Medicine,
National Yang-Ming University School of Medicine,
Taipei, Taiwan, Republic of China

2006 - 2007

Professor:

Institute of Emergency and Critical Care Medicine,
National Yang-Ming University School of Medicine,
Taipei, Taiwan, Republic of China

2007 - present

Professor:

Institute of Pharmacology,
National Yang-Ming University School of Medicine,
Taipei, Taiwan, Republic of China

2007 - present

Vice Director:

Cardiovascular Research Center,
National Yang-Ming University,
Taipei, Taiwan, Republic of China

2007 - present

 

Licenses:

Physician, Republic of China

1984 - present

Specialist, Society of Internal Medicine, Republic of China

1989 - present

Specialist, Taiwan Society of Cardiology

1991 - present

Specialist for critical care, Society of Emergency and Intensive Care Medicine, Republic of China

1991 - present

Instructor, Taiwan Society of Cardiology

1994 - present

Specialist for interventional cardiology, Taiwan Society of Cardiology

2007 - present

 

Society Membership:

Taiwan Society of Internal Medicine

Taiwan Society of Cardiology

Taiwan Society of Lipids and Atherosclerosis

Society of Emergency and Intensive Care Medicine, Republic of China

Taiwan Society of Atherosclerosis and Vascular Diseases

Taiwan Society of Interventional Cardiology

Formosan Medical Association, Taiwan

American Heart Association, USA

International Atherosclerosis Society

American Diabetes Association, USA

Asian Pacific Society of Cardiology

 

Society Appointments:

Editorial Board:

Taiwan Society of Cardiology

2001 - 2007

Hypertension Board:

Taiwan Society of Cardiology

2001 - 2005,
2007 - present

Academic Board:

Taiwan Society of Cardiology

2007 - present

Secretory General:

Taiwan Society of Lipids and Atherosclerosis

2003 - 2006

President:

Taiwan Society of Lipids and Atherosclerosis

2006 - present

Council member:

Asian Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD)

2006 - present

Fellow:

College of Asian Pacific Society of Cardiology

2007 - present

Board of Director:

International lipid investigation beurou Taiwan branch

2007 - present

Board:

Taiwan Hypertension Society

2008 - present

 

International Meeting Appointments:

Deputy Secretary General:

The 5th International Congress on Essential Fatty Acids and Eicosanoids

Taipei, Taiwan

2002

Domestic Faculty:

The 16th Asian Pacific Congress of Cardiology

Taipei, Taiwan

2007

Scientific Advisory Board:

TThe 14th World Congress on Heart Disease -
the International Academy of Cardiology Annual Scientific Sessions 2008

Toronto, ON, Canada

2008

International Faulty:

The 17th Asian Pacific Congress of Cardiology

Kyoto, Japan

2009

International Advisory Board:

The 15th International Symposium on Atherosclerosis

Boston, Massachusetts, USA

2009

 

Government Appointments:

Board, NHI Dispute Mediation Committee, Department of Health, Exacutive Yuan, R.O.C. (Taiwan)

2002 - present

Consultation Board, Department of Health, Taipei City Government, R.O.C. (Taiwan)

2003 - present

 

Honor and Awards:

Clinical Teaching Award, Taipei Veterans General Hospital, Taiwan, R.O.C.

1994

"Who's Who in the World", Marquis Who's Who, U.S.A., since 16 th ed.

1999 - present

Annual Academic Paper Award, Taiwan Society of Atherosclerosis and Vascular Diseases

1999

Annual Academic Paper Award, Taiwan Society of Cardiology

2000

"The Asia 500 – leaders for the new century", Barons Who's Who, U.S.A.

2000

"Who's Who in the Medicine and Health Care", Marquis Who's Who, U.S.A., since 5 th ed.

2004 - present

Annual Academic Paper Award, Yen-Tjing Ling Medical Foundation, Taiwan, R.O.C.

2004

Annual Academic Paper Award, Taipei Veterans General Hospital, Taiwan, R.O.C.

2004

Nong Ting Award, Taiwan Society of Cardiology

2007

Great academic achievement award in 50 years of Taipei Veterans General Hospital,
Taipei Veterans General Hospital, Taiwan, R.O.C.

2008

Annual Academic Paper Award, Taipei Veterans General Hospital, Taiwan, R.O.C.

2008


 

Review for Projects and Funding:

Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.

1999 - present

Member of peer review panels, N ational Science Council (NSC), Government of Taiwan, R.O.C.

2004 - present

Project assessor , National Health and Medical Research Council (NHMRC), Australian Government

2008 - present

Project assessor , Institute of Biomedical Sciences, Academia Sinica, Government of Taiwan, R.O.C.

2008 - present

 

Review for Medical Journals:

Since 1994:

Journal of Chinese Medical Association

Acta Cardiologica Sinica

Since 1995:

European Heart Journal

Since 1999:

American Journal of Cardiology

Since 2002:

Journal of Biomedical Science

Since 2003:

International Journal of Cardiology

European Journal of Clinical Investigation

Since 2004:

Pharmacogenomics Journal

Journal of Formosan Medical Association

Acta Pharmacologica Sinica

Since 2005:

Atherosclerosis

Since 2006:

British Journal of Nutrition

Since 2007:

Journal of Pharmacy and Pharmacology

Diabetes Care

Hypertension

Clinica Chimica Acta

Molecular Medicine

Clinical Biochemistry

Clinical Cardiology

Biomarker Insight

International Journal of Molecular Sciences

Pharmacology & Therapeutics

Since 2008:

International Journal of Biomedical Science

Diabetes

Free Radical Research

Diabetes Research and Clinical Practice

Heart and Vessels

Bioorganic & Medicinal Chemistry Letters

Kidney International

Archives of Medical Research

Arteriosclerosis, Thrombosis and Vascular Biology

Experimental Biology and Medicine

Molecular Nutrition and Food Research

Since 2009:

Current Drug Therapy

BMC (Bio-Med Central) Cardiovascular Disease

Journal of the American College of Cardiology

The Chinese Journal of Physiology

Disease Marker

Journal of Inflammation

Metabolism

Chemico-Biological Interactions

 

Editorial appointments (Review for Medical Journals):

Executive Editor

Acta Cardiologica Sinica

1999 - 2001

Editor

Clinical Medicine

2000

Deputy Editor

Journal of Chinese Medical Association

2001- 2002

Senior Editor

Acta Cardiologica Sinica

2001- 2003

Editorial Board Member

Acta Cardiologica Sinica

2001 - 2007

Managing Editor

Frontiers in Bioscience

2006 - present

Editorial Board Member

Open Biochemistry Journal (OBIO)

2007 - present

Editorial Board Member

International Journal of Pharmacology

2007 - present

Editorial Board Member

Journal of Biological Sciences

2007 - present

Editorial Board Member

Journal of Medical Sciences

2007 - present

Editorial Board Member

Research Journal of Cardiology

2007 - present

Editorial Board Member

Trends in Medical Research

2007 - present

Editorial Board Member

Clinica Chimica Acta

2008 - present


 

Medical Publications:

Original articles (*corresponding author)

1.      Chen JW, Lin SL, Kong CW, Wang SP, Chang MS. Motion artifact presenting as atypical ventricular tachycardia -- a case report. Acta Cardiol Sin 1991; 7: 108-113.

2.      Chen JW*, Chen CH, Liou JY, Hsu TL, Lin SL, Wang SP, Chang MS. Evaluation of myocardial dysfunction by radionuclide ventricular ejection fraction in heart failure patients after prosthetic valve replacement. Acta Cardiol Sin 1992; 8: 63-72.

3.      Chen JW*, Chen CH, Wang SP, Chang MS. Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension -- Placebo-control, double-blind, randomized and crossover study. Chin Med J (Taipei) 1992; 50: 321-330.

4.      Chen SA, Tsang WP, Hsia CP, Wang DC, Chiang CE, Yeh HI, Chen JW, Chiou CW, Ting CT, Kong CW, Wang SP, Chiang BN, Chang MS. Comparison of direct-current and radiofrequency ablation of free wall accessory atrioventricular pathways in Wolff-Parkinson-White syndrome. Am J Cardiol 1992; 70: 321-326.

5.      Chen SA, Tsang WP, Hsia CP, Wang DC, Chiang CE, Yeh HI, Chen JW, Ting CT, Kong CW, Wang SP, Chiang BN, Chang MS. Catheter ablation of accessory atrioventricular pathway in 114 symptomatic patients with Wolff-Parkinson-White syndrome -- A comparative study of direct-current and radiofrequency ablation. Am Heart J 1992; 124: 356-365.

6.      Chen SA, Tsang WP, Wang DC, Hsia CP, Chen JW, Chiang CE, Ting CT, Wang SP, Chiang BN, Chang MS. Safety and efficacy of a modified catheter-mediated ablation of accessory pathways. Jpn Heart J 1992; 33: 303-326.

7.      Chen SA, Tsang WP, Hsia CP, Wang DC, Chiang CE, Yeh HI, Chen JW, Ting CT, Kong CW, Wang SP, Chiang BN, Chang MS. Catheter ablation of free wall accessory pathways in 89 patients with Wolff-Parkinson-White syndrome --Comparisony of direct current and radiofrequency ablation. Eur Heart J 1992; 13: 1329-1338.

8.      Chen SA, Tsang WP, Hsia CP, Wang DC, Chiang CE, Yeh HI, Chen JW, Chiou CW, Ting CT, Kong CW, Wang SP, Chiang BN, Chang MS. Radiofrequency catheter ablation for treatment of Wolff-Parkinson-White syndrome -- short- and long-term follow-up. Int J Cardiol 1992; 37: 199-207.

9.      Chen SA, Tsang WP, Hsia CP, Wang DC, Chiang CE, Yeh HI, Chen JW, Ting CT, Chiou CW, Kong CW, Wang SP, Chiang BN, Chang MS. Reappraisal of intermediate-term follow-up of radiofrequency catheter ablation of accessory atrioventricular pathways for treatment of Wolff-Parkinson-White syndrome. Jpn Heart J 1992; 33: 755-769.

10.  Liu CP, Ting CT, Yang TM, Chen JW, Chang MS, Maughan L, Lawrence W, Kass DA. Reduced left ventricular compliance in human mitral stenosis -- Role of reversible internal constraint. Circulation 1992; 85: 1447-1456.

11.  Sharir T, Marmor A, Ting CT, Chen JW, Liu CP, Chang MS, Yin FCP, Kass DA. Validation of a method for noninvasive measurement of central arterial pressure. Hypertension 1993; 21: 74-82.

12.  Ting CT, Yang TM, Chen JW, Chang MS, Yin FCP. Arterial hemodynamics in human hypertension -- Effects of angiotensin converting enzyme inhibition. Hypertension 1993; 22: 839-846.

13.  Chung CT, Chen JW, Wu TR, Chen KK, Wang JH, Yang AH, Chang MS. Secondary hypertension due to renin secreting tumor: a case report. Chin Med J (Taipei) 1994; 54: 188-192.

14.  Mar GY, Chen JW*, Wang SP, Chang MS. Electrocardiographic and coronary angiographic findings in patients with posterior wall myocardial infarction. Acta Cardiol Sin 1995; 11: 115-121.

15.  Ting CT, Chen JW, Chang MS, Yin FCP. Arterial hemodynamics in human hypertension -- Effects of the calcium channel antagonist nifedipine. Hypertension 1995; 25: 1326-1332.

16.  Lee WL, Chen JW*, Kong CW, Wang JJ, Ting CT, Chan WL, Wang SP, Chang MS. Changes in cardiac autonomic activities in patients with syndrome X - a study of spectral analysis of heart rate variability. Angiology 1996; 47: 929-939.

17.  Chen JW, Ting CT, Chen CI, Mar GY, Hsu NW, Wang SP, Chang MS. Coronary microvascular dysfunction is associated with ischemic-like electrocardiogram during exercise in patients with anginal chest pain and normal coronary angiograms. Jpn Heart J 1996; 37: 865-878.

18.  Hsu NW, Chen JW*, Jen SL, Mar GY, Lee WL, Wang SP, Chang MS. Different exercise performance between aged patients with syndrome X and those with coronary artery disease. Chin Med J (Taipei) 1996; 58: 241-247.

19.  Chen JW*, Lee WL, Hsu NW, Lin SJ, Ting CT, Wang SP, Chang MS. Effects of short-term treatment of nicorandil on exercise-induced myocardial ischemia and abnormal cardiac autonomic activity in microvascular angina. Am J Cardiol 1997; 80: 32-38.

20.  Jen SL, Chen JW*, Lee WL, Wang SP. Efficacy and safety of fenofibrate or gimfibrozil on serum lipid profiles in Chinese patients with type IIb hyperlipidemia: a single-blind, randomized, and cross-over study. Chin Med J (Taipei) 1997; 59: 217-224.

21.  Chen JW*, Lin SJ, Ting CT. Syndrome X: pathophysiology and clinical management. Chin Med J (Taipei) 1997; 60:177-183.

22.  Hsu NW, Chen CI, Mar GY, Chen WL, Chen JW, Kong CW, Wang SP. New stenosis on proximal coronary segment after directional atherectomy -two case reports. Angiology 1997; 48: 911-918.

23.  Hsu NW, Chen JW*, Jen SL, Kuo BI, Lee WL, Mar GY, Lin SJ, Wang SP, Chang MS. Differentiating syndrome X from coronary artery disease by treadmill exercise test in patients with chest pain and exercise-induced myocardial ischemia. Angiology 1998; 49: 13-24.

24.  Wang L, Ma W, Markovich R, Chen JW, Wang PH. Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I. Circ Res 1998; 83: 516-522.

25.  Chen JW, Jen SL, Lee WL, Hsu NW, Lin SJ, Ting CT, Chang MS, Wang PH. Differential glucose tolerance in dipper and nondipper essential hypertension: the implications of circadian blood pressure regulation on glucose tolerance in hypertension. Diabetes Care 1998; 10: 1743-1748.

26.  Lee WL, Chen JW, Lin SJ, Hsu NW, Chang MS, Ting CT. Parasympathetic withdrawal antedates dynamic myocardial ischemia in patients with syndrome X. Int J Cardiol 1998; 66: 253-260.

27.  Lee WL, Chen JW, Ting CT, Lin SJ, Wang PH. Changes of the insulin-like growth factor I system during acute myocardial infarction: Implications on left ventricular remodeling. J Clin Endocrinol Metab 1999; 84: 1575-1581.

28.  Chen JW*, Ting CT, Chen YH, Wu TC, Hsu NW, Lin SJ, Chang MS. Differential coronary microvascular function in patients with left ventricular dysfunction of unknown cause---- implication for possible mechanism of myocardial ischemia in early stage of cardiomyopathy. Int J Cardiol 1999; 69: 251-261.

29.  Lee WL, Chen JW, Ting CT, Ishiwata T, Lin SJ, Korc M, Wang PH. Insulin-like growth factor I improves cardiovascular function and suppresses apoptosis of cardiomyocytes in dilated cardiomyopathy. Endocrinology 1999; 140: 4831-4840.

30.  Wu TC, Chen JW*, Hsu NW, Chen YH, Lin SJ, Wang SP, Ding YA, Chang MS. Coronary flow reserve and ischemic-like electrocardiogram in patients with symptomatic mitral valve prolapse. Jpn Heart J 1999; 40: 571-578.

31.  Wu TC, Chen JW*, Chen CI, Mar GY, Hsu NW, Chen YH, Lin SJ, Ding YA, Wang SP, Chang MS. Early alteration of coronary hemodynamics in late restenosis after coronary angioplasty. Jpn Heart J 1999; 40: 535-548.

32.  Chen JW*, Hsu NW, Ting CT, Lee WL, Lin SL, Chang MS. Clinical strategy for coronary microvascular dysfunction in patients with chest pain of unknown cause --- the role of treadmill exercise testing. Acta Cardiol Sin 1999; 15: 73-79.

33.  Chen YH, Chen JW, Wu TC, Ding YA, Wang SP, Chang MS. Randomized, double-blind, placebo-controlled trial of the platelet glycoprotein IIb/IIIa inhibitor abciximab in patients undergoing high-risk angioplasty. Chin Med J (Taipei) 2000; 63: 8-15.

34.  Wu TC, Chen YH, Chen JW*, Chen LC, Lin SJ, Ding Philip YA, Wang SP, Chang MS. Impaired forearm reactive hyperemia is related to late restenosis after coronary stenting. Am J Cardiol 2000; 85: 1071-1076.

35.  Chen JW*, Hsu NW, Ting CT, Lin SJ, Chang MS. Differential coronary hemodynamics and left ventricular contractility in patients with syndrome X. Int J Cardiol 2000; 75: 49-57.

36.  Pan WH, Chen JW, Fann C, Jou YS, Wu SY. Linkage analysis with candidate genes: the Taiwan young-onset hypertension genetic study. Hum Genet. 2000; 107: 210-215.

37.  Chen LC, Chen JW, Wu MH, Liu JC, Lan GY, Wu TC, Chern MS, Chang CY, Chang MS, Ding PYA. Differential coronary artery calcification detected by electron beam computed tomography as an indicator of coronary stenosis among patients with stable angina pectoris. Can J Cardiol 2001; 17: 667-676.

38.  Chen LC, Ding PYA, Chen JW, Wu MH, Liu JC, Lan GY, Chern MS, Chang CY, Chang MS. Coronary artery calcium determined by electron beam computed tomography for predicting angiographic coronary artery disease in moderate to high risk Chinese patients. Cardiology 2001; 95: 183-189.

39.  Chen YL, Yang SP, Shiao MS, Chen JW, Lin SJ. Salvia miltiorrhiza inhibits intimal hyperplasia and monocyte chemotactic protein-1 expression after balloon injury in cholesterol-fed rabbits. J Cell Biochem 2001; 83: 484-493.

40.  Chen LC, Chen JW*, Wu MH, Liu JC, Lan GY, Ding PYA, Chang MS. Differential Coronary Calcification on electron beam computed tomography between syndrome X and coronary artery disease in patients with chronic stable angina pectoris. Chest 2001; 120: 1525-1533.

41.  Chen YH, Lin SJ, Ku HH, Shiao MS, Lin FY, Chen JW, Chen YL. Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-α-treated human aortic endothelial cells. J Cell Biochem 2001; 82: 512-521.

42.  Wu SY, Fann C, Jou YS, Chen JW, Pan WH. Association between markers in chromosomal region 17q23 and young-onset hypertension; a TDT study. J Med Genet 2002; 39: 42-44.

43.  Chen YH, Lin SJ, Chen JW, Ku HH, Chen YL. Magnolol attenuates VCAM-1 expression in TNF-α-treated human aortic endothelial cells and in vivo in the aortas of cholesterol-fed rabbits. Brit J Pharmacol 2002; 135: 37-47.

44.  Lin SJ, Yang TH, Chen YH, Chen JW, Kowk CF, Shiao MS, Chen YL. Effects of Gingko biloba extract on the proliferation of vascular smooth muscle cells in vitro and on intimal thickening and interleukin-1β expression after balloon injury in cholesterol-fed rabbits in vivo. J Cell Biochem 2002; 85: 572-582.

45.  Tsai JC, Liu JC, Kao CC, Tomlinson B, Kao PF, Chen JW, Chen P. Beneficial effects on blood pressure and lipid profile of programmed exercise training in subjects with white coat hypertension. Am J Hypertens 2002; 15: 571-576.

46.  Chen YH, Lin SJ, Lin MW, Tsai HL, Kuo SS, Chen JW, Charng MJ, Wu TC, Chen LC, Ding YA, Pan WH, Jou YS, Chau LY. Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients. Hum Genet 2002; 111: 1-8.

47.  Chen JW*, Hsu NW, Wu TC, Lin SJ, Chang MS. Long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome X. Am J Cardiol 2002; 90: 974-982.

48.  Lin SJ, Chen JW, Chen YL. Natural antioxidants inhibit atherogenesis and attenuate balloon injury-induced intimal hyperplasia. In “ Essential Fatty Acids and Eicosanoids: Invited Papers from the Fifth International Congress” edited by Yung-Sheng Huang, Shing-Jong Lin, and Po-Chao Huang, published by The American Oil Chemists Society, AOCS press in Urbana, IL. USA 2003; 267-273.

49.  Chen JW*, Yin WH, Chan WL, Young MS, Kong CW, Chang MS. Impairment of coronary microvascular function in patients with neurally mediated syncope. Pacing Clin Electrophysiol 2003; 26(Pt I): 605-612.

50.  Lin CP, Lin WT, Leu HB, Wu TC, Chen JW*. Differential mononuclear cell activity and endothelial inflammation in coronary artery disease and cardiac syndrome X. Int J Cardiol 2003; 89: 53-62.

51.  Jen HL, Chen JW, Yin WH, Ho SJ, Young MS, Hsu TL. Transesophageal echocardiographic determination of coronary flow reserve – a validate study. Acta Cardiol Sin 2003; 19: 101-108.

52.  Chen JW*, Chen YH, Lin FY, Chen YL, Lin SJ, Ginkgo biloba Extract inhibits TNF-α-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells. Arterioscler Thromb Vasc Biol 2003, 23: 1559-1566.

53.  Yin WH, Chen JW, Jen HL, Chiang MC, Huang WP, Feng AN, Lin SJ, Young MS. The prognostic value of circulating soluble cell adhesion molecules in patients with chronic congestive heart failure. Eur J Heart Fail 2003; 5: 507-516.

54.  Leu HB, Chiu TY, Chen JW*, Wu TC, Ding P YA, Chang MS. Acute and late clinical outcomes of coronary balloon angioplasty with or without stenting in diabetes – The fact in the “real world”. J Chin Med Assoc 2003; 66: 699-708.

55.  Chen YH, Chau LY, Lin MW, Chen LC, Yo MH, Chen JW, Lin SJ. Heme oxygenase-1 gene promotor microsatellite polymorphism is associated with angiographic restenosis after coronary stenting. Eur Heart J 2004; 25: 39-47.

56.  Huang PH, Leu HB, Chen JW, Cheng CM, Huang CY, Tuan TC, Ding PY, Lin SJ. Usefulness of attenuated heart rate recovery immediately after exercise to predict endothelial dysfunction in patients with suspected coronary artery disease. Am J Cardiol 2004; 93: 10- 13.

57.  Lin SJ, Shyue SK, Liu PL, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL. Adenovirus-mediated overexpression of catalase attenuates oxLDL-induced apoptosis in human aortic endothelial cells via AP-1 and C-Jun N-terminal kinase/extracellular signal-regulated kinase mitogen-activated protein kinase pathways. J Mol Cell Cardiol 2004; 36: 129-139.

58.  Chiu TY, Leu HB, Wu TC, Chen JW*, Ding PYA, Chang MS. Endovascular stenting treatment for drug-refractory hypertension due to ostial stenosis of transplanted renal artery. J Chin Med Assoc 2004; 67: 189-192.

59.  Yin WH, Chen JW, Jen HL, Chiang MC, Huang WP, Feng AN, Young MS, Lin SJ. Independent prognostic value of elevated high-sensitivity C-reactive protein in chronic heart failure. Am Heart J 2004; 147: 931-938.

60.  Chen JW*, Wu SY, Pan WH. Clinical characteristics of young-onset hypertension – implications for different genders. Int J Cardiol 2004, 96: 65-71.

61.  Leu HB, Lin CP, Lin WT, Wu TC, Chen JW*. Risk stratification and prognostic implication of plasma biomarkers in non-diabetic patients with stable coronary artery disease – The role of high sensitivity C-reactive protein. Chest 2004, 126: 1032-1039.

62.  Chen JW*, Lin FY, Chen YH, Wu TC, Chen YL, Lin SJ, Carvedilol Inhibits TNF-α-induced Endothelial Transcription Factor Activation, Adhesion Molecule Expression and Adhesiveness to Human Mononuclear Cells. Arterioscler Thromb Vasc Biol 2004, 24: 2075-2081.

63.  Huang CY, Lai CH, Lin SJ, Chen JW*. The “ribbon sign” of aortic coarctation. Clin Cardiol 2004, 27: 652.

64.  Leu HB, Wu CC, Wu TC, Lin SJ, Chen JW*. Fluvastatin reduces oxidative stress, decreases serum monocyte chemotactic protein-1 level and improves endothelial function in patients with hypercholesterolemia. J Formos Med Assoc 2004, 103: 914-920.

65.  Huang CY, Huang CH, Chen JW, Lin SJ, Lu TM. Atherosclerotic Left Main Coronary Artery Aneurysm—Case Reports. International Journal of Angiology 2004, 13: 89-91.

66.  Chen HS, Shan YX, Yang TL, Lin HD, Chen JW, Lin SJ, Wang PH. Insulin deficiency down-regulated Hsp60 and IGF-1 receptor signaling in diabetic myocardium. Diabetes 2005, 54: 175-181.

67.  Lin SJ, Shyue SK, Hung YY, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL. Superoxide Dismutase Inhibits the Expression of Vascular Cell Adhesion Molecule-1 and Intracellular Cell Adhesion Molecule-1 Induced by Tumor Necrosis Factor-α in Human Endothelial Cells Through the JNK/p38 Pathways. Arterioscler Thromb Vasc Biol 2005; 25: 334-340.

68.  Huang PH, Leu HB, Chen JW, Lin SJ. Heart rate recovery after exercise and endothelial function-two important factors to predict cardiovascular events. Prev Cardiol 2005; 8: 167-170.

69.  Wu TC, Leu HB, Lin WT, Lin CP, Lin SJ, Chen JW*. Plasma matrix metalloproteinase-3 level is an independent prognostic factor in stable coronary artery disease. Eur J Clin Invest 2005; 35: 537–545.

70.  Huang PH, Chen LC, Leu HB, Ding PY, Chen JW, Wu TC, Lin SJ. Enhanced coronary calcification determined by electron beam CT is strongly related to endothelial dysfunction in patients with suspected coronary artery disease. Chest 2005; 128: 810-815.

71.  Leu HB, Chen JW, Wu TC, Ding YA, Lin SJ, Charng MJ. Effects of Fluvastatin, a HMG CoA reductase inhibitor, on serum levels of interleukin-18 and matrix metalloproteinase-9 in patients with hypercholesterolemia. Clin Cardiol 2005, 28: 423-428.

72.  Ye ZX, Yu WC, Hsueh CM, Leu HB, Chen JW, Lin SJ. Antiphospholipid syndrome presenting as intracardiac thrombus with pulmonary embolism. Circ J 2005, 69: 1290-1292.

73.  Yin WH, Chen JW*, Tsai C, Chiang MC, Young MS, Lin SJ. L-arginine improves endothelial function and reduces LDL oxidation in patients with stable coronary artery disease. Clin Nutrition 2005, 24: 988-997.

74.  Barrios V, Amabile N, Paganelli F, Chen JW, Allen C, Levonas A, Massaad R, Vandormael K. Lipid-altering efficacy of switching from atorvastatin 10 mg/day to ezetimibe/simvastatin10/20 mg/day compared to doubling the dose of atorvastatin in hypercholesterolemic patients with atherosclerosis or coronary heart disease. Int J Clin Practice 2005, 59: 1377-1386.

75.  Chen P, Jou YS, Fann C, Chen JW, Wu SY, Pan WH. Lipoprotein lipase gene is linked and associated with hypertension in Taiwan young-onset hypertension genetic study. J BioMed Sci 2005, 12: 651-658.

76.  Leu HB, Chen JW, Lin SJ. Circulating Endothelial Progenitor Cells. N Engl J Med 2005, 353: 2613-2614.

77.  Huang CY, Wu TC, Lin WT, Leu HB, Lin CP, Lin SJ, Chen JW*. Effects of simvastatin withdrawal on serum matrix metalloproteinases in hypercholesterolemic patients. Eur J Clin Invest 2006; 36: 76-84.

78.  Chen JW*, Chen YH, Lin SJ. Long-term exposure to oxidized low density lipoprotein enhances tumor necrosis factor-α-stimulated endothelial adhesiveness of monocytes by activating superoxide generation and redox-sensitive pathways. Free Radic Biol Med 2006; 40: 817-826.

79.  Leu HB, Lin CP, Lin WT, Wu TC, Lin SJ, Chen JW*. Circulating mononuclear superoxide production and inflammatory markers to long-term prognosis in patients with cardiac syndrome X. Free Radic Biol Med 2006; 40: 983-991.

80.  Huang PH, Leu HB, Chen JW, Wu TC, Lu TM, Ding YA, Lin SJ. Comparison of endothelial vasodilator function, inflammatory markers and N-terminal-pro-brain natriuretic peptide in patients with or without chronotropic incompetence to exercise test. Heart 2006; 92: 609-614.

81.  Chen HS, Jia J, Su HF, Lin HD, Chen JW, Lin SJ, Yang JY, Lai HC, Mestril R, Wang PH. Downregulation of the constitutively expressed Hsc70 in diabetic myocardium is mediated by insulin deficiency. J Endocrinol 2006; 190: 433-440.

82.  Chen YL, Hu CS, Lin FY, Chen YH, Sheu LM, Ku HH, Shiao MS, Chen JW, Lin SJ. Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta. J Cell Biochem 2006; 98: 618-631.

83.  Yin WH, Jen HL, Chen JW, Lin SJ, Young MS. Differential effects of peroxisome proliferator-activated receptor ligands and sulfonylurea plus statin treatment on plasma concentrations of adipokines in type 2 diabetes with dyslipidemia. Diabetes Metab 2006; 32: 229-235.

84.  Chen YH, Lin SJ, Chen YL, Liu PL, Chen JW*. Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules. Cardiovasc Hematol Disord Drug Targets 2006; 6: 279-304.

85.  Lin FY, Chen YH, Lin YW, Tasi JS, Chen JW, Yang TL, Wang HJ, Li CY, Chen YL, Li CY, Lin SJ. The Role of Human Antigen R, an RNA-binding Protein, in Mediating the Stabilization of Toll-Like Receptor 4 mRNA Induced by Endotoxin. A Novel Mechanism Involved in Vascular Inflammation. Arterioscler Thromb Vasc Biol 2006; 26: 2622-2629.

86.  Lin FY, Chen YH, Tasi JS, Chen JW, Yang TL, Wang HJ, Li CY, Chen YL, Lin SJ. Endotoxin Induces Toll-Like Receptor 4 Expression in Vascular Smooth Muscle Cells via NADPH Oxidase Activation and Mitogen-Activated Protein Kinase Signaling Pathways. Arterioscler Thromb Vasc Biol 2006; 26: 2630-2637.

87.  Lin SJ, Shyue SK, Shih MC, Chu TH, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL. Superoxide dismutase and catalase inhibit oxidized low-density lipoprotein-induced human aortic smooth muscle cell proliferation: Role of cell-cycle regulation, mitogen-activated protein kinases, and transcription factors. Atherosclerosis 2007; 190: 124-134.

88.  Huang PH, Leu HB, Chen JW, Wu TC, Lu TM, Ding PYA, Lin SJ. Decreased heparin cofactor II activity is associated with impaired endothelial function determined by brachial ultrasonography and predicts cardiovascular events. Int J Cardiol 2007; 114: 152-158.

89.  Lin SJ, Lee IT, Chen YH, Lin FY, Sheu LM, Ku HH, Shiao MS, Chen JW, Chen YL. Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells. J Cell Biochem 2007; 100: 372-384.

90.  Huang PH, Chen JW, Lu TM, Ding PYA, Lin SJ. Combined us of endothelial function assessed by brachial ultrasound and high-sensitive C-reactive protein in predicting cardiovascular events. Clin Cardiol 2007; 30:135-140.

91.  Yin WH, Chen JW*, Jen HL, Wang JJ, Huang WP, Feng AN, Chiang MC, Yang YN, Yang MS, Lin SJ. Increased endothelial monocyte adhesiveness is related to clinical outcomes in chronic heart failure. Int J Cardiol 2007; 121: 276-283.

92.  Lin SJ, Chen YH, Lin FY, Hsieh LY, Wang SH, Lin CY, Wang YC, Ku HH, Chen JW, Chen YL. Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity. J Cell Biochem 2007; 101: 642-653.

93.  Lin FY, Chen YH, Chen YL, Wu TC, Li CY*, Chen JW*, Lin SJ*. Ginkgo biloba Extract inhibits endotoxin-induced human aortic smooth muscle cell proliferation via suppression of toll-like receptor 4 expression and NADPH oxidase activation. J Agric Food Chem 2007; 55: 1977-1984.

94.  Chen YH, Lin SJ, Lin FY, Wu TC, Tsao CR, Huang PH, Liu PL, Chen YL, Chen JW*. High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms. Diabetes 2007; 56: 1559–1568.

95.  Huang PH, Chen YH, Leu HB, Chen YL, Wu TC, Chen JW*, Lin SJ*. Vascular endothelial function and circulating endothelial progenitor cells in patients with cardiac syndrome X. Heart 2007; 93: 1064-1070.

96.  Yin WH, Chen JW, Feng AN, Lin SJ, Young S. Multimarker approach to risk stratification among patients with advanced chronic heart failure. Clin Cardiol 2007; 30: 397-402.

97.  Wu TC, Chen YH, Leu, HB, Chen YL, Lin FY, Lin SJ*, Chen JW*. Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis. Free Radic Biol Med 2007; 43: 1508-1522.

98.  Wang RY, Chung CM, Fann CS, Yang HC, Chen JW, Jong YS, Jou YS, Lo HM, Ho FM, Kang CS, Chen CC, Chang HC, Shyue SK, Pan WH. Genome-wide scan for quantitative ACE activity in Taiwan Young-Onset Hypertension Study. Hum Hered 2008; 65: 85-90.

99.  Ye ZX, Leu HB, Wu TC, Lin SJ, Chen JW*. Baseline Serum Matrix Metalloproteinase-9 Level Predicts Long-Term Prognosis after Coronary Revascularizations in Stable Coronary Artery Disease. Clin Biochem 2008; 41: 292-298.

100.     Lin CP, Chen YH, Lin WT, Leu HB, Liu TZ, Huang SL*, Chen JW*. Direct effect of statins on homocysteine-induced endothelial adhesiveness - potential impact to human atherosclerosis. Eur J Clin Invest 2008; 38: 106-116.

101.     Lin CP, Chen YH, Chen JW, Leu HB, Liu TZ, Liu PL, Huang SL. Cholestin (Monascus purpureus rice) inhibits homocysteine-induced reactive oxygen species generation, nuclear factor-κB activation, and vascular cell adhesion molecule-1 expression in human aortic endothelial cells. J Biomed Sci 2008; 15: 183-196.

102.     Huang CC, Leu HB, Wu TC, Lin SJ, Chen JW*. Clinical predictors of the response to short-term thiazide treatment in non-diabetic essential hypertensives. J Hum Hypertension 2008; 22: 329-337.

103.     Huang PH, Lu TM, Wu TC, Lin FY, Chen YH, Chen JW, Lin SJ. Usefulness of combined high-sensitive C-reactive protein and N-terminal-probrain natriuretic peptide for predicting cardiovascular events in patients with suspected coronary artery disease. Coron Artery Dis 2008; 19: 187-193.

104.     Sung SH, Wu TC, Lin SJ, Chen JW*. Efficacy of a very-low-dose combination of peridopril and indapamide – preterax compared with cilazapril monotherapy in patients with inadequate blood pressure control -- a randomized, double-blind, add-on study. J Chin Med Assoc 2008; 71: 247–253.

105.     Chen YH, Chau LY, Chen JW, Lin SJ. Serum bilirubin and ferritin levels link between heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients. Diabetes Care 2008; 31: 1615-1620.

106.     Huang SS, Huang PH, Chen YH, Sung SH, Chiang KH, Chen JW, Lin SJ. Plasma heparin cofactor II activity is an independent predictor of future cardiovascular events in patients after acute myocardial infarction. Coron Artery Dis 2008; 19: 597-602.

107.     Wu CC, Wen SC, Yang CW, Pu SY, Tsai KC, Chen JW*. Plasma ADMA predicts restenosis of arteriovenous fistula. J Am Soc Nephro 2009; 20: 213-222.

108.     Chen P, Jou YS, Fann CS, Chen JW, Chung CM, Lin CY, Wu SY, Kang MJ, Chen YC, Jong YS, Lo HM, Kang CS, Chen CC, Chang HC, Huang NK, Wu YL, Pan WH. Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides. Hum Mutat 2009; 30: 49-55.

109.     Lin CP, Chen YH, Leu HB, Lin SJ, Chen YL, Huang SL, Chen JW*. Anti-inflammatory strategies for homocysteine-related cardiovascular disease. Front Biosci 2009; 14: 3836-3845.

110.     Leu HB, Lin WT, Lin CP, Wu TC, Lin SJ, Chen JW*. Predictors of inexplicable coronary artery spasm during coronary angiography in patients with stable angina - the role of intravascular oxidative stress. Clin Biochem 2009; 42: 570-577.

111.     Yang HC, Liang YJ, Wu YL, Chiang KM, Ho HY, Ting CT, Lin TH, Sheu SH, Tsai WC, Chen JH, Leu HB, Yin WH, Chiu TY, Chen CI, Fann C SJ, Wu JY, Lin TN, S Lin SJ, Chen YT, Chen JW*, Pan WH*. Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan. 2009; 4: e5459.

112.     Chiang KH, Huang PH, Huang SS, Wu TC, Chen JW, Lin SJ. Plasma levels of soluble receptor for advanced glycation end products are associated with endothelial function and predict cardiovascular events in nondiabetic patients. Coron Artery Dis 2009; 20: 267-273.

113.     Huang PH, Chen YH, Wang CH, Chen JS, Tsai HY, Lin FY, Wu TC, Sata M*, Chen JW*, Lin SJ*. Matrix metalloproteinase-9 is essential for ischemia-induced neovascularization by modulating the function and behaviors of bone marrow-derived, circulating endothelial progenitor cells. Arterioscler Thromb Vasc Biol 2009; in press

114.     Huang WP, Yin WH, Chen JW, Jen HL, Young MS, Lin SJ. Fenofibrate attenuates endothelial monocyte adhesion in chronic heart failure: an in vitro study. Eur J Clin Invest 2009 Jun 15. [Epub ahead of print]

 

Conference papers and abstracts:

1.      Chen JW*, Lee WL, Kong CW. Parasympathetic withdrawal and impaired coronary flow reserves in patients with syndrome X. (in 67th annual scientific sessions of American Heart Association). Circulation 1994; 90 (suppl 4, part 2): I-57.

2.      Chen JW*, Ting CT, Wang SP, Chang MS. Coronary microvascular function in patients with early cardiomyopathy. (in 17th congress of the European Society of Cardiology). Eur Heart J 1995; 16 (abstr. suppl.): 297.

3.      Chen JW*, Jen SL, Lee WL, Ting CT, Chang MS, Wang PH. Differential glucose tolerance in dipper and non-dipper hypertension. Program and abstracts book of 79th annual meeting of American Endocrine Society 1997:476.

4.      Chen JW*, Won JGS, Ting CT, Lee WL, Chang MS, Wang PH. Intracardiac gradient of circulating IGF I and left ventricular mass in essential hypertension. Program and abstracts book of 80th annual meeting of American Endocrine Society 1998.

5.      Wu TC, Chen JW, Chen YH, Hsu NW, Lin SJ, Wang SP, Chang MS. Association of vascular endothelial dysfunction with angiographic restenosis after coronary stenting. (in 47th annual scientific session of American College of Cardiology). J Am Coll Cardiol 1998; 31 (suppl A):366A.

6.      Chen JW*. Genetic linkage study of young-onset hypertension in Taiwan (in 30th annual scientific sessions of Taiwan Society of Cardiology). Acta Cardio Sini, 2000; 16 (suppl):34.

7.      Chen JW*, Hsu NW, Lin SJ, Chang MS. Enalapril reduces plasma asymmetric dimethylarginine, improves exercise-induced myocardial ischemia and coronary microvascular function in patients with syndrome X. (in 73th annual scientific sessions of American Heart Association). Circulation 2000; 102 (suppl II) ii-244.

8.      Pan WH, Chen JW, Fann C, Jou YS, Wu SY. Markers of Lipoprotein Lipase and ACE Are Linked to Young-Onset Hypertension in Taiwan. Genome 2000 基因體分析研討會 Taipei, Taiwan.

9.      Chen JW*, Lin FY, Chen YH, Yang TL; Chen YL; Lin SJ. Carvedilol, Aβ-Adrenoreceptor Antagonist, Inhibits TNF-α stimulated Transcription Factor Activation, Adhesion Molecule Expression and Adhesiveness to Mononuclear Cells in Human Vascular Endothelial Cells (in the XIIIth international symposium on Atherosclerosis). Atheroscler Suppl. 2003 Sep; 4(2):1-375.

10.  Chen YH, Lin SJ, Chen JW*. Activation of mononuclear cells and their adhesiveness to vascular endothelial cells under chronic oxidative stress in clinical and experimental atherosclerosis (in the XIIIth international symposium on Atherosclerosis, Kyoto, Japan). Atheroscler Suppl. 2003 Sep; 4(2):1-375.

11.  Chen YH, Chen YL, Lin FY, Chen JW, Lin SJ. Modulation of the gene expression profile by Ginkgo Biloba in TNF-α-treated human aortic endothelial cells. Int J Cardio 2004; 97(Suppl. 2): S54.

12.  Lin FY, Chen YL, Chen YH, Chen JW, Lin SJ. Lipopolysaccharide induces toll-like receptor 4 expression through generation of reactive oxygen species and increasing of RNA stability in human aortic smooth muscle cells: Inhibition by Ginkgo Biloba extract. Int J Cardio 2004; 97(Suppl. 2):S55.

13.  Yin WH, Chen JW, Jen HL, Wang JJ, Huang WP, Feng AN, Chiang MS, Yang YN, Young MS, Lin SJ. Inhibitory effect of simvastatin an HMG-COA reductase inhibitor on endothelial monocyte adhesion in patients with severe congestive heart failure. Int J Cardio 2004; 97(Suppl. 2): S59.

14.  Pan WH, Chen P, Jou YS, Fann C, Chen JW, Wu SY, Chung CM, Lin CY, Chen YC, Kang MJ, Jong YS. Lipoprotein lipase variants genetically associated with hypertension and metabolic syndrome, in the 4th Asian-Pacific Congress of Hypertension, Seoul, Korea. 2005 June; 1-4.

15.  Chen YH, Lin SJ, Lin FY, Wu TC, Tsao CR, Chen YL, Huang PH, Chen JW*. High glucose induces endothelial progenitor cell dysfunction with reducing endothelial nitric oxide synthase phosphorylation, in the XIVth international symposium on Atherosclerosis, Rome, Italy. Atheroscler Suppl. 2006 June; 7(3)

16.  Fong MC, Leu HB, Wu TC, Lin SJ, Chen JW*. Progression to diabetes mellitus in essential hypertensive patients, in the 21st Scientific Meeting of the International Society of Hypertension and 5th Asian-Pacific Congress of Hypertension, Fukuoka, Japan. J Hypert 2006; 24 (Suppl.): S173.

17.  Leu HB, Ye ZX, Wu TC, Lin SJ, Chen JW*. Baseline Serum Matrix Metalloproteinase-9 Level Predicts the Long-Term Prognosis of Different Coronary Revascularizations, in Asian Pacific Society of Cardiology Poster Session 2, The 71st Annual Scientific Meeting of the Japanese Circulation Society. Circulation journal, 2007, 71 (Suppl.): 323.

18.  Chen JS, Lin SJ, Chen JW*, Ginkgo biloba extract (EGb 761) stimulates heme oxygenase-1 expression by activating nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase pathway in human aortic endothelial cells, in the 39th Annual Scientific Meeting of the Japan Atherosclerosis Society, Osaka, Japan,2007.

19.  Yin WH, Chen JW, Lin SJ. Adhesion molecules in congestive heart failure, in the 16th scientific meeting of Asian-Pacific Congress of Cardiology, Taipei, Taiwan, ROC, December 12-16, 2007. Int J Cardio 2007; 122 (Suppl. 1):S25-S26.

20.  Tsai HY, Chen YH, Lin FY, Chen JH, Lin SJ, Chen JW*. Ginkgo biloba extract upregulates endothelial nitric oxide synthase and heme oxygenase-1 expression in high glucose-stimulated human aortic endothelial cells, in the 16th scientific meeting of Asian-Pacific Congress of Cardiology, Taipei, Taiwan, ROC, December 12-16, 2007. Int J Cardio 2007; 122 (Suppl. 1): S41-S42.

21.  Huang PH, Sata M, Chen YH, Chen JW, Lin SJ. Mechanistic link between endothelial progenitor cells and impairment of ischemia-induced neovascularization in matrix metalloproteinase 9-deficient mice, in the 16th scientific meeting of Asian-Pacific Congress of Cardiology, Taipei, Taiwan, ROC, December 12-16, 2007. Int J Cardio 2007; 122 (Suppl. 1):S47-S48.

22.  Chen JS, Chen YH, Lin SJ, Chen JW*. Ginkgo biloba extract (egb 761) attenuated high glucose-induced endothelial icam-1 expression via mapk and IL-6 related sata pathway in HAECS, in the 16th scientific meeting of Asian-Pacific Congress of Cardiology, Taipei, Taiwan, ROC, December 12-16, 2007. Int J Cardio 2007; 122 (Suppl. 1):S63.

23.  Leu HB, Chung CM, Lin SJ, Jong YS, Pan WH, Chen JW*. Association of the adiponectin gene and serum adiponectin level to the presence of metabolic syndrome in hypertensive patients and their families, in the 16th scientific meeting of Asian-Pacific Congress of Cardiology, Taipei, Taiwan, ROC, December 12-16, 2007. Int J Cardio 2007; 122 (Suppl. 1):S90-S91.

24.  Chiu TY, Chen JW, Kang CS, Lin CP, Chou HY, Chern CI. Clinical implications of coronary plaques within the proximal coronary segments in subclinical coronary atherosclerosis, in XVIth International Symposium on DRUGS AFFECTING LIPID METABOLISM (DALM), New York, New York, USA, October 4-7, 2007. J Clinic Lipidology 2007; 1: 408.

25.  Huang CC, Leu HB, Wu TC, Lin SJ, Chen JW*. Clinical predictors of the response to short-term thiazide treatment in non-diabetic essential hypertensives, in the 22nd Scientific Meeting of the International Society of Hypertension, Berlin, Germany, June 14-18, 2008. J Hypert 2008.

26.  Yeh JS, Leu HB, Wu TC, Lin SJ, Chen JW*. Baseline serum matrix metalloproteinase-9 level predicts long-term prognosis after coronary revascularization in stable coronary artery disease, in the 42nd Congress of the European Society of Cardiology, Munich, Germany, August 30- September 3, 2008. Eur Heart J 2008.

27.  Huang CC, Leu HB, Wu TC, Lin SJ, Chen JW*. Baseline aldosterone/renin ratios predict responses to thiazide in essential hypertension, particularly for already-treated patients, in the 81st annual scientific sessions of American Heart Association, New Orleans, U.S.A, November 8-12, 2008. Circulation 2008.

 

Chinese Papers:

1.      陳肇文 (Chen JW*). 氧化壓力和動脈硬化之發生--氧化壓力在高膽固醇症之角色. 臨床醫學, 2000.01: 58-61.

2.      陳隆景, 陳肇文 (Chen JW), 丁予安. 以電子束電腦斷層評估冠狀動脈鈣化指數及診斷冠狀動脈疾病. 臨床醫學, 2000.02: 71-75.

3.      吳道正, 陳肇文 (Chen JW), 丁予安. 周邊血管疾病治療的新進展. 臨床醫學, 2000.04: 274-278.

4.      呂信邦; 陳肇文 (Chen JW*). 心血管的構造及功能. 健康世界, 2002; 201:68-72.

5.      吳道正; 陳肇文 (Chen JW*). 週邊血管疾病. 健康世界, 2002; 202:65-68.

6.      吳道正; 陳肇文 (Chen JW*). 週邊血管疾病要怎麼治療? 健康世界, 2002; 202:69.

7.      鄭浩民; 陳肇文 (Chen JW*), 腎動脈粥狀硬化狹窄. 臨床醫學, 2003.10: 272-281.

8.      陳肇文 (Chen JW*). 從實證醫學觀點談高血脂症以降血脂藥物治療之爭議. 台灣醫學 2004, 8: 857-861.

9.      陳肇文 (Chen JW*). 高血壓的新觀念--從年紀來看高血壓的診斷與治療. 臨床醫學, 2006.07: 18-23.

 

Invited/Keynote lectures (since 2006):

1.      Chen JW*. Adhesion molecules and atherogenesis. (invited lecture) in 第一屆海峽兩岸冠心病現代治療策略高峰論壇, Shanghai, China, March 2-3, 2006.

2.      Chen JW*. Current Status of Hypertension Genetic Study - Genetic study of young-onset hypertension in Taiwan (invited lecture) in 吳德祿教授基金會2007年度學術研討會, Taipei, Taiwan, ROC, March 18, 2007.

3.      Chen JW*. The role of oxidative stress in atherogenesis- The effects of different drugs with antioxidant property (invited lecture) in 第二屆海峽兩岸心血管疾病高峰學術研討會, Shanghai, China, April 15-16, 2007.

4.      Chen JW*. Updated Lipid Lowering Treatment – What is the target? How to get it? (invited lecture)in the continuing teaching program of 台北市醫師公會, Taipei, Taiwan, ROC, July 20, 2007.

5.      Chen JW*. The impairment of endothelial progenitor cells in diabetes and cardiovascular diseases - the potential mechanisms and future implications (invited lecture), in the 18th Great Wall International Congress of Cardiology, Beijing, China. October 10-13, 2007.

6.      Chen JW*. Comprehensive Lipid Lowering Treatment – What is the target? How to get it? (Invited lecture), in the annual scientific meeting of Formosa Medical Association, Taipei, Taiwan, ROC, November 11-12, 2007.

7.      Chen JW*. The impairment of endothelial progenitor cells in diabetes and cardiovascular diseases - the potential mechanisms and future implications (invited lecture), in the 15th annual meeting of Japanese Society of Vascular Biology and Medicine (JSVBM), Fukuoka, Japan, November 19-20, 2007.

8.      Chen JW*. Oxidative stress in atherogenesis - the role of drugs with antioxidant property (keynote lecture), in the annual scientific meeting of Taiwan Society of Cardiology, Taipei, Taiwan, ROC, December 14, 2007. Int J Cardio 2007; 122 (Suppl. 1): S9-S10.

9.      Chen JW*. Medical therapy for acute myocardial infarction (invited lecture) in the 16th scientific meeting of Asian-Pacific Congress of Cardiology, Taipei, Taiwan, ROC, December 12-16, 2007. Int J Cardio 2007; 122 (Suppl. 1): S6.

10.  Chen JW*. The role of endothelial progenitor cells in diabetes and cardiovascular diseases – the potential mechanisms and future implications (invited lecture), in “New Advances in Vascular Biology Research” in 2008 Summer Scientific Meeting of Taiwan Society of Cardiology – Conjuncting the 20th Anniversary of National Cheng Kung University Hospital, Tainan, Taiwan, ROC. June 14-15, 2008.

11.  Chen JW*, Lin SJ. Oxidative stress and atherogenesis- the role of drugs with antioxidant capacity (invited lecture), in the 14th World Congress on the Heart Disease and International Academy of Cardiology Annual Scientific Sessions 2008, Toronto, Canada, July 26-29, 2008. J of Heart Dis 2008; 6:67.

12.  Chen JW*. Identification of biomarkers for diagnosis and prognosis of cardiovascular diseases (invited lecture), in the 19th Great Wall International Congress of Cardiology, Beijing, China. October 23-27, 2008.

13.  Chen JW*. Biomarkers for advanced risk stratification (invited lecture), in the 17th Asian Pacific Congress of Cardiology, Kyoto, Japan, May 20-23, 2009.

 

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