20150303 嚴老師合照-與106級醫學系陳政葦.嚴珮嘉-1.JPG嚴錦城(Jiin-Cherng Yen

地址陽明大學藥理學研究所 研究大樓四樓 414

電話: 886-2-2826-7090

E-mail: jcyen@ym.edu.tw

 

學歷

1984      台北醫學院藥學系學士

1990      台灣大學藥理學研究所碩士

1999      陽明大學藥理學研究所博士

 

經歷

1991      陽明醫學院藥理學科助教

1992      陽明大學醫學系藥理學科講師

2000      陽明大學醫學系藥理學科助理教授

2011      陽明大學醫學系藥理學科副教授

 

學術榮譽

1998         榮獲台灣藥理學會優秀論文獎

1999         榮獲第九屆王民寧優秀論文獎

2002-16   連續15年醫學系網路教學評估獲選優良教師

2008         榮獲陽明大學教學優良獎

2010         榮獲陽明大學醫學院優良教師獎座

2015         榮獲陽明大學教學優良獎

2016         榮獲醫學系PBL教學優良教師

 

研究興趣

1.     腦幹孤獨核調節心血管功能之機轉研究:腎上腺髓質素與硫化氫的角色

2.     榮陽頭痛研究團隊:以動物模式探討偏頭痛之機制及其治療新標的。

 

近期著作

1.     Su HH, Chu YC, Liao JM, Wang YH, Jan MS, Lin CW, Wu CY, Tseng CY, Yen JC*, Huang SS*. (2017) Phellinus Linteus Mycelium alleviates myocardial ischemia-reperfusion injury through autophagic regulation. Frontiers in Pharmacology (in press) [SCI] (*co-correspondence)

2.     Shih HJ, Yen JC, Chiu AW, Chow YC, Pan WH, Huang CJ. (2016) FTY720 inhibits germ cell apoptosis in testicular torsion/detorsion. Journal of Surgical Research 202:155-164. [SCI]

3.     Shih HJ, Yen JC, Chiu AW, Chow YC, Pan WH, Wang TY, Huang CJ. (2015) FTY720 mitigates torsion/detorsion-induced testicular injury in rats. Journal of Surgical Research 196:325-331. [SCI]

4.     Huang YH, Yen JC, Lee JJ, Liao JF, Liaw WJ, Huang CJ. (2015) P2X7 is involved in the anti-inflammation effects of levobupivacaine. Journal of Surgical Research 193:407-414. [SCI]

5.     Wong YK, Chou MK, Shen YC, Wang YH, Yen JC, Chen CF, Lin SK, Liao JF. (2014) Preventive effect of baicalein on methamphetamine-induced amnesia in the passive avoidance test in mice. Pharmacology 93: 278-285. [SCI]

6.     Huang YH, Yen JC, Lee JJ, Liao JF, Liaw WJ, Huang CJ. (2013) Suppressive effects of levobupivacaine on endotoxin-induced microglial activation. Journal of Surgical Research 184:989-996. [SCI]

7.     Shen YC, Yen JC, Liou KT. (2013) Ameliorative effects of caffeic acid phenethyl ester on an eccentric exercise-induced skeletal muscle injury by down-regulating NF-κb mediated inflammation. Pharmacology 91: 219-228. [SCI]

8.     Chien SI, Yen JC, Kakadiya R, Chen CH, Lee TC, Su TL, Tsai TH. (2013) Determination of tissue distribution of potent antitumor agent ureidomustin (BO-1055) by HPLC and its pharmacokinetic application in rats. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 917-918: 62-70. [SCI]

9.     Li FCH, Yen JC, Chan SHH, Chang AYW. (2012) Defunct brain stem cardiovascular regulation underlies cardiovascular collapse associated with methamphetamine intoxication. Journal of Biomedical Science 19: 16. [SCI]

10.  Lin CC, Yen JC, Wu YT, Lin LC, Tsai TH. (2012) Chemical analysis and transplacental transfer of oseltamivir and oseltamivir carboxylic acid in pregnant rats. PLoS One 7: e46062. [SCI]

11.  Li FCH, Yen JC, Chan SHH, Chang AYW. (2012) Bioenergetics failure and oxidative stress in brain stem mediates cardiovascular collapse associated with fatal methamphetamine intoxication. PLoS One 7: e30589. [SCI]

12.  Yen DHT, Chen LC, Shen YC, Chiu YC, Ho IC, Lou YJ, Chen IC, Yen JC. (2011) Protein Kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats. Journal of Biomedical Science 18: 32. [SCI]

13.  Chern CM, Liou KT, Wang YH, Liao JF, Yen JC*, Shen YC.* (2011) Andrographolide inhibits PI3K/AKT-dependent NOX2 and iNOS expression to protect mice against hypoxia-ischemia induced oxidative brain injury. Planta Medica 77: 1669-1679. [SCI] (*co-correspondence)