Dr. R. Stephen Phillips, Professor

Institute of Tropical Medicine, National Yang-Ming University (NYMU)

Major Offices held External of University of Glasgow

 

Educational Background ¡G

The Manchester Grammar School 1954-61
State Scholarship Award 1960
University College London - 1961-64. BSc Honours (Ist Class) in Zoology 1964. Awarded Frances Perch Bedford Prize in Zoology for top First Class Honours student.
St John's College and Department of Animal Pathology, University of Cambridge 1964-67. PhD University of Cambridge 1968. Title of thesis: "Studies on Babesia rodhaini in laboratory animals"
Member of Institute of Biology 1983
Elected Fellow of Institute of Biology 1985Molecular Parasitology

Honours ¡G

Member of the British Empire 2006

Major Appointments¡G

2004 ~ Present Chair of Board of Directors, Scottish Accreditation Board
2004-2006 Senior Senate Assessor for Discipline
2002-2006 Senate Assessor for Discipline
1997 Personal Chair in Zoology renamed Chair of Parasitology
1995-2000 Head of Division of Infection and Immunity, University of Glasgow
1994-95 Deputy Head, Division of Molecular and Cellular Biology, University of Glasgow
1990-93 Dean, Faculty of Science, University of Glasgow, Scotland
1987-90 Vice Dean, Faculty of Science, University of Glasgow, Scotland
1985-91 Head of Department, Department of Zoology, University of Glasgow, Scotland
1983 Titular Professor in Department of Zoology, University of Glasgow, Scotland
1978-83 Senior Lecturer in Zoology, University of Glasgow, Scotland
1972-78 Lecturer in Zoology, University of Glasgow, Scotland
1967-72 Research Scientist in the Division of Parasitology, National Institute for Medical Research, Mill Hill, London.
* E-mail: S.Phillips@bio.gla.ac.uk
* Tel: 886-2- 2826-7172 / Fax: 886-2-28214670

 

Major Offices held External of University of Glasgow¡G

2003-2006 President British Section of Society for Protozoology
2002 ~ Present Annual Visiting Professor in Parasitology at the Institute of Tropical Medicine, National Yang-Ming University, Taipei.
2000-2003 Vice President British Section of Society for Protozoology
1988-96 Sub-Committee Member - Medical Research Council Tropical Medicine Research Board
1987-89 President, Royal Society for Tropical Medicine & Hygiene, Scottish Branch
1985-87 Vice President, Royal Society for Tropical Medicine & Hygiene, Scottish Branch
1988-92 Chairman World Health Organisation Steering Committee on Immunology of Malaria
1984-92 Member of Steering Committee on 'Immunology of Malaria', World Health Organisation, Geneva. Chairman selected Scientific Working Group Meetings for WHO 1984-1992.
1978-82 on the use of nuclear techniques in research and control of ticks and tick-borne diseases in livestock
1971& Consultant with International Atomic Energy Agency
1982-85 Treasurer British Section Society for Protozoology
1981-85 Council Member Royal Society for Tropical Medicine and Hygiene, Scottish Branch
1978-80 Council Member British Society for Parasitology
1971 General Council and Senate Open University

External Examiner - Taught Course¡G

    National University of Ireland (University Colleges of Cork, Dublin and Galway), Liverpool School of
    Tropical Medicine, London School of Hygiene and Tropical Medicine, University College London,
    Liverpool University.Molecular Parasitology

Learned Societies¡G

    British Society for Parasitology, British Section of Society of Protozoologists, Royal Society of Tropical Medicine and Hygiene, British Society for Immunology, Institute of Biology.

Referee¡G

    Paper Assessment for: Nature, International Journal for Parasitology, Experimental Parasitology, Parasite Immunology, Parasitology, ICRS, Journal of Parasitology, Immunology, Proceedings of the Royal Society, Molecular and Biochemical Parasitology, Parasitology Today, Clinical and Experimental Immunology.

    Editorial Board - ICRS - Medical Science, Parasite Immunology, Experimental Parasitology

    Editor - 2000 appointed one of two editors of Parasitolgy and in 2006 appointed Senior Editor of Parasitology.

    Consultant for Blackwell, Blackie, University College Cork, University College Dublin

    Project evaluation for WHO, MRC (College of Experts), SERC, AFRC, BBSRC, NERC, Wellcome Trust, Nuffield Foundation, Wolfson Trust, Leverhulme Trust.

    Site Visits - MRC, Wellcome Trust, WHO


Publication list:

    1. Phillips, R.S. 1967. Active immunization of rats against Babesia (nuttallia) rodhaini using a killed vaccine. Parasitology 57: 11 P

    2. Phillips, R.S. 1968. The isolation of a population of Babesia rodhaini resistant to pools of antiserum. Parasitology 58: 19-20.

    3. Brown, I.N., Brown, K.N., Trigg, P.I. & Phillips, R.S. 1968. The effect of antiserum on the

    4. erythocytic stage of Plasmodium knowlesi in vivo and in vitro. Parasitology 58: 7p.

    5. Phillips, R.S. 1969. The protective activity of serum from immune rats against Babesia rodhaini Parasitology 59: 357-364

    6. Phillips, R.S. 1969. Babesia rodhaini infections in the rat after the acute primary parasitaemia, Parasitology 59: 349-356

    7. Phillips, R.S. 1969. The role of the spleen in relation to natural and acquired immunity to infections of Babesia rodhaini in the rat. Parasitology 59: 637-648

    8. Phillips, R.S. 1970. Plasmodium berghei: passive transfer of immunity by antisera and cells ExpL ParasitoL 27: 479-495

    9. Phillips, R.S. 1970. Transfer of immunity of Plasmodium berghei with spleen cells - one role of the transferred cells. Trans. R. Soc. trop. Med. Hyg. 64: 6-7

    10. Phillips, R.S. 1970. Resistance of rnice and rats to Babesia rodhaini challenge after inoculation with irradiated Babesia rodhaini infected red cells. Trans. R. Soc. trop. Med. Hyg. 64:470

    11. Phillips, R.S. 1970. Resistance of mice and rats to challenge by Babesia rodhaini after inoculation with irradiated red cells infected with Babesia rodhaini. Nature, Lond. 227: 1255

    12. Brown, K.N., Brown, I.N., Phillips, R.S., Trigg, P.I., Hills, L.A., Wolstencroft, R.A. & Dumonde, D.C. 1970. Immunity to malaria: studies with Plasmodium knowlesi. Trans. R. Soc. trop. Med. Hyg. 64: 3-5.

    13. Brown, K.N., Brown, I.N., Trigg, P.I., Phillips, R.S. & Hills, L.A. 1970. Immunity to malaria. 11. The serological responses of monkeys sensitized by drug suppressed infections or by dead parasitized cells in Freund's adjuvant. Expl. Parasitol. 28: 318-338

    14. Brown, K.N., Phillips, R.S., Brown, I.N., Trigg, P.I., Wolstencroft, R.A. & Dumonde, D.C. 1970. Immunity to malaria: a sterilizing immune response in monkeys vaccinated against Plasmodium knowlesi infection. J. Parasitol. 56: 37-38.

    15. Brown, K.N., Brown, I.N. & Phillips, R.S. 1970. Immunity to chronic malaria: studies with Plasmodium knowlesi. J. Parasitol. 56 37

    16. Phillips, R.S. 197 1. Evidence that piroplasms can undergo antigenic variation. Nature, 231: 323

    17. Phillips, R.S. 1971. Immunity of rats and rnice following injection with 60-Co irradiated Babesia rodhaini infected red cells. Parasitoloky 62: 221-23 1.

    18. Phillips, R.S. 1971. Antigenic variation in Babesia rodhaini demonstrated by immunization with irradiated parasites. Parasitology 63: 315-322

    19. Brown, K.N. & Ph'illips, R.S. 1971. The role of thymus-derived lymphocytes in protective immunity to malaria. Trans. R. Soc. trop. Med. Hyg. 65: 7

    20. Brown, K.N., Phillips, R.S. & Brown, I.N. 1971. The passive transfer of variant-specific protection in malaria. Trans. R. Soc. trop. Med. Hyg. 65: 7-8

    21. Phillips, R.S. & Jones, V.E. 1972. Immunity to Plasmodium berghei in rats: maximum level of protective antibody activity are associated with eradication of the infection. Parasitology 64: 117-127

    22. Phillips, R.S., Trigg, P.I., Bartholomew, R.K. & Scott-Finnegan, T.J. 1972. Culture of Plasmodium falciparum in vitro: a subculture technique used for demonstrating antiplasmodial activity in serum from some Gambians, resident in an endemic malarious area. Parasitology 65: 525-535

    23. Trigg, P.I., Phillips, R.S. & Gutteridge, W.E. 1972. The effect of radiation on Plasmodium knowlesi. Int. J. Parasit. 2: 131-138

    24. Phillips, R.S. 1973. Review of studies on protective immunization against piroplasmosis with irradiated parasitized cells. Isotopes and Radiation in Parasitology 111. 173-177

    25. Phillips, R.S. & Wakelin, D. 1973. The effect of concurrent protozoal infections upon the expulsion of Trichuris muris from mice. Parasitology 67: XIX

    26. Phillips, R.S., Trigg, P.I. & Gutteridge, W.E. 1973. A note on the effect of gamma irradiation on Plasmodium knowlesi. Isotopes & Radiation in Parasitology III: 185-186

    27. Phillips, R.S. & Wakelin, D. 1974. Suppression of immunity in mice to the nematode Trichuris muris by concurrent infection with rodent piroplasms. Trans. R. Soc. trop. Med. Hyg. 68: 276

    28. Phillips, R.S. 1974. Antigenic character of the Plasmodia. Proc. 3rd Int. Congr. Parasit. 2: 1106-1107.

    29. Phillips, R.S. 1974. The interaction between an ascites tumour and rodent malarias in mice Parasitology 69: 11-12

    30. Phillips, R.S. 1974. Protective antibodies in immunity to rodent malaria. Proc. 3rd Int. Congr. Parasit. 2: 1064.

    31. Phillips, R.S. 1974. Immunity to malaria parasites. In: Basic Research on Malaria. Technical Report ERO-5-74 US Army R. & D.O. pp. 59-67

    32. Alexander, J. & Phillips, R.S. 1974. The suppressive effect of Trypanosoma brucei on the growth of Leishmania mexicana in mice. Trans. R. Soc. trop. Med. Hyg. 68: 273

    33. Brown, I.N. & Phillips, R.S. 1974. Immunity to Plasmodium berghei in rats: passive serum transfer and the role of the spleen. Infection and Immunity 10: 1213-1218

    34. Bruce, R.G. & Phillips, R.S. 1974. The effect of concurrent malaria and trypanosome infections on immunity to Trichinella spiralis in ntice. Proc. 3rd Int. Congr. Parasit. 3: 1188

    35. Phillips, R.S., Selby, G.R. & Wakelin, D. 1974. The effect of Plasmodium berghei and Trypanosoma brucei infections of the immune expulsion of the nematode Trichuris muris from mice. Int J. Parasit 4: 409-415

    36. Alexander, J. & Phillips, R.S. 1975. Immunity to Leishmania mexicana in mice. J. Protozool, 22: 48A

    37. McDonald, V. & Phillips, R.S. 1975. Immunity to Plasmodium chabaudi in mice: attempts to understand the role of different lymphoid cell types. J. Protozool. 22: 54A

    38. Phillips, R.S., Rahman, A.K. & Wilson, R.J.M. 1975. Invasion of human red cells by Plasmodiumfalciparum in vitro. Trans. R. Soc. trop. Med. Hyg. 69: 432

    39. Phillips, R.S. 1976. B.C.G. and Pertussis as potentiators of protection induced in mice by injecting irradiated Plasmodium berghei infected red cells. Parasitology 73(2): XH.

    40. Phillips, R.S., Wilson, R.J.M. & Pasvol, G. 1976. Differentiation of gametocytes of Plasmodiumfalciparum in vitro. Trans. R. Soc. trop. Med. Hyg. 70: 286

    41. Phillips, R.S. & Waketin, D. 1976. Trichuris muris: effect of concurrent infections with rodent piroplasms on immune expulsion from mice. Expl. ParasitoL 39: 95- 1 00.

    42. McDonald, V. & Phillips, R.S. 1976. Adoptive transfer of immunity to Plasmodium chabaudi in mice using B-cell enriched (T-cell depleted) and B-cell depleted (T-cell enriched) spleen cell populations. Trans. R. Soc. trop. Med. Hyg. 70: 286.

    43. Wilson, R.J.M. & Phillips, R.S. 1976. Method to test inhibitory antibodies in human sera to wild populations of Plasmodiumfalciparum. Nature, Lond. 263: 132-134

    44. McDonald, V. & Phillips, R.S. 1977. The expression of immunity to Plasmodium chabaudi in irradiated mice. J. Protozool. 24: 4A

    45. Phillips, R.S. & McDonald, V. 1977. Plasmodium chabaudi in irradiated mice: depression of the early primary parasitaemia. Parasitology 75: XXXEII-TV

    46. McDonald, V. & Phillips, R.S. 1978. Plasmodium chabaudi in mice: adoptive transfer of immunity with enriched populations of spleen T and B lymphocytes. Immunology 34: 821-830

    47. Phillips, R.S., Brown, K.N. & Hills, L. 1978. Immunity to Plasmodium berghei in rats: reduced protective activity of immune spleen cells when transferred to recently infected rats. Trans. R. Soc. trop., Med. Hyg. 72: 92-94

    48. Alexander, J. & Phillips, R.S. 1978. Leishmania mexicana and Leishmania tropics: inhibition of gowth in mice by concurrent infections of Trypanosoma brucei. Expl. Parasitol. 44: 136- 142

    49. Alexander, J. & Phillips, R.S. 1978. Leishmania tropics and Leishmania mexicana: cross- immunity in mice. Expl. Parasitol. 45: 93-100

    50. Kusel, J.R. & Phillips, R.S. 1978. The interaction of malaria parasites and Schistosoma mansoni in mice. Trans. R. Soc. trop. Med. Hyg. 72: 642-643

    51. McDonald, V. & Phillips, R.S. 1978. Increase in non-specific antibody mediated cytotoxicity in malarious mice. Clin. exp. Immunol. 34: 159-163.

    52. Panton, L.J. & Phillips, R.S. 1978. The effects of BCG organisms on the course of Plasmodium chabaudi, P. berghei and Trypanosoma brucei infections in mice. Trans. R. Soc. trop. Med. Hyg. 72: 643

    53. Phillips, R.S. & Wilson, R.J.M. 1978. Cryopreservation of Plasmodium falciparum in liquid nitrogen. Trans. R. Soc. trop. Med. Hyg. 72: 643-644

    54. Phillips, R.S., Wilson, R.J.M. & Pasvol, G. 1978. Differentiation of gametocytes in microcultures of human blood infected with Plasmodium falciparum. J. Protozool. 25: 394-398

    55. McLean, S.A. & Phillips, R.S. 1979. Investigations of the relapse parasitaemias in Plasmodium chabaudi infected mice. Parasitology 79: XXIV

    56. Alexander, J. & Phillips, R.S. 1980. Leishmania mexicana and Leishmania tropica major: adoptive transfer of immunity in rnice. Expl. ParsitoL 49: 34-40

    57. McDonald, V. & Phillips, R.S. 1980. Plasmodium chabaudi: adoptive transfer of immunity with different spleen cell populations and development of protective activity in the serum of lethally irradiated recipient n-@ce. ExpL ParasitoL 49: 26-33

    58. Pearson, C.D., McLean, S.A. & Phillips, R.S. 1980. Antibody responses to malaria parasites in Marbrook cultures: preliminary results. Parasitology 81: 1 H- I IVI

    59. Phillips, R.S. 1980. Immune mechanisms in Babesia-infected animals. In: Isotope and Radiation Research on Animal Diseases and their Vectors. LAEA, 67-76

    60. McLean, S.A. & Phillips, R.S. 1980. Further studies on the occurrence of a recrudescent population in a Plasmodium chabaudi infection- in rnice. Parasitology 81: XII.

    61. Carson, C.A. & Phillips, R.S. 1981. The immunological response of the vertebrate host to Babesia. In: Babesiosis. Eds. M. Ristic and J.P. Kreier pp. 411-443. Academic Press

    62. Gero, A.M. Tetley, K., Coombs, G.H. & Phillips, R.S. 1981. Dihydroorotate dehydrogenase, orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in Plasmodiumfalciparum. Trans. R. Soc. trop. Med. ParasitoL 75: 719-721

    63. Budge, K.M. & Phillips, R.S. 1981. The use of Bordetella pertussis to potentiate the immune response to Plasmodium chabaudi following chemotherapy. Trans. R. Soc. trop. Med. Hyg. 75: 324

    64. Carlow, C.K.S., Wakelin, D. & Phillips, R.S. 198 1. Interaction between Trichinella spiralis and Babesia infections in mice. Trans. R. Soc. trop. Med. Hyg. 75: 324

    65. Gray, G.D. & Phillips, R.S. 1981 Use of sorbitol in cryopreservation of Babesia. Res. Vet. Sci. 30: 388-389

    66. McLean, S.A., Pearson, C.D. & Phillips, R.S. 1981. Antigenic variation in Plasmodium chabaudi infection in NIH mice. Trans. R. Soc. trop. Med. Hyg. 75: 602

    67. McLean, S.A., Pearson, C.D. & Phillips, R.S. 1982. Plasmodium chabaudi: evidence of antigenic variation during recrudescent parasitaemias in mice. Expl. Parasitol. 54: 296- 302

    68. Phillips, R.S., McLean, S.A., Pearson, C.D. & Tetley, K, Plasmodium 1982 Antibody responses to chabaudi in vitro. J. Protozool, 29: 321.

    69. McLean, S.A., Pearson, C.D. & Phillips, R.S. 1982. Plasmodium chabaudi: relationship between the occurrence of recrudescent parasitaemias in mice and the effective levels of acquired immunity. Expl. Parasitol, 54: 213-22 1.

    70. Gray, G.D. & Phillips, R.S. 1983. Suppression of primary and secondary antibody responses and inhibition of antigen priming during Babesia microti infection in mice. Parasite Immunology. 5: 123-134

    71. G.D. & Phillips, R.S. 1983. Influence of infective dose, degree of host anaemia and multiparasitism of erythrocytes on Babesia microti and Babesia hylomysci parasitaemias in mice. Int. J. Parasitol. 13: 399-404.

    72. McLean, S.A., Pearson, C.D., Phillips, R.S. & Walliker D. 1982. The effect of mosquito transmission on variant expression in Plasmodium chabaudi. J. Protozool, 29: 321

    73. Phillips, R.S. 1983. Malaria. Edward Arnold Book in the Institute of Biology Series. No. 152

    74. Pearson, C.D., McLean, S.A., Tetley, K.M. & Phillips, R.S. 1983. Induction of secondary antibody responses to Plasmodium chabaudi in vitro. Clin. exp. Immunol. 52: 121-128

    75. McLean, S.A., Pearson, C.D. & Phillips, R.S. 1983. Cloned populations of Plasmodium chabaudi from recrudescent parasitaemias. Proc. 2nd Int. Cong. Malaria and Babesiosis Annecy, France

    76. McLean, S.A., Pearson, C.D. & Phillips, R.S. 1983. Further studies on clones of recrudescent populations of Plasmodium chabaudi. Parasitology, 87. XXI-XXH

    77. Phillips, R.S. 1984. Babesia divergens in splenectomized rats. Res. Vet. Sci. 36: 251-255

    78. Phillips, R.S., Reid, G.M., McLean, S.A. & Pearson, C.D. 1984. Babesia divergens: some observations using the rat adapted parasite. Parasitology, 89: XXIX

    79. Trenholme, K.A. & Phillips, R.S. 1985. Plasmodium falciparum: the effect of feeder cells in vitro. Trans. R. Soc. trop. Med. Hyg. 79: 871

    80. Giles, N. & Phillips, R.S. 1985. A note on the production and use of antisera for the detection of part-digested sticklebacks in predator stomach-content samples. J. Fish Biol. 27: 827-829

    81. McLean, S.A., Pearson, C.D. & Phillips, R.S. 1986. Antigenic variation in Plasmodium chabaudi: analysis of parent and variant populations by cloning. Parasite Immunology. 8: 415-424

    82. McLean, S.A., MacDougall, L. & Phillips, R.S. 1986. An indirect fluorescent antibody test which recognizes antigenic variants of Plasmodium chabaudi. IRCS Medical Science. 14: 896-897

    83. Trenholme, K.R. & Phillips, R.S. 1986. Plasmodium falciparum: further studies with feeder cells. Trans. R. Soc. trop. Med. Hyg. 80: 986-987

    84. G.M. & Phillips, R.S. 1986 Antigenic diversity in Babesia divergens Trans. R. Soc trop. Med. Hyg. 80: 986

    85. Ben Musa, N., Phillips, R.S. 1986 Immunity to Babesia divergens in the rat Trans. R. Soc trop Med. Hyg. 80: 895

    86. Phillips, R'S., Reid, G.M., McLean, S.A. & Pearson, C.D. 1987. Antigenic diversity in Babesia divergens: preliminary results with three monoclonal antibodies to the rat adapted strain. Res. Vet. Sci. 42: 96-100

    87. Kumararatne, D.S., Phillips, R.S., Sinclair, D., Parrott, D.M.V. & Forrester, J.B. 1987. Lymphocyte migration in murine malaria during the primary patent parasitaemia of Plasmodium chabaudi infections. Clin. exp. Immunol. 69: 65-77

    88. McLean, S.A., Phillips, R.S., Pearson, C.D. & Walliker, D. 1987. Antigenic reversion in Plasmodium chabaudi after mosquito-transmission. Parasitology, 94: 443-449

    89. Hassan,.F., Phillips, R.S. & Coombs, G.H. 1987. Purine metabolising enzymes in Babesia divergens. ParasitologyResearch, 73: 121-125.

    90. Phillips, R.S., Trenholme, K.R., MacDougall, L.M., Pyott, A., McLean, S.A. & Walker, E. 1987. Adaptation of Plasmodium falciparum to continuous culture using human and murine feeder cells. Med. Sci. Res. 15: 1167-1168

    91. McLean, S.A., MacDougall, L.M. & Phillips, R.S. 1987. Antigenic variation early in Plasmodium chabaudi infections. Proc. 3rd Int. Cong. Malaria and Babesiosis, Annecy, France, p.76

    92. McLean, S.A., MacDougall, L.M., Jaffa, W. & Phillips, R.S. 1987. Strain specificity of parasite clearance during Plasmodium chabaudi infections. Proc. 3rd Int. Cong. Malaria and Babesiosis, Annecy, France, p.77

    93. Trenholme, K.R. & Phillips, R.S. 1989. The use of murine feeder cells in the cultivation of Plasmodiumfalciparum asexual blood stages. Parasitology Research 75, 518-521

    94. Trenholme, K.R., MeMonagle, F.A. & Phillips, R.S. 1990. The effect of a fibroblast feeder layer, L-cysteine and 2-mercapteoethanol on the growth Plasmodiumfalciparum in vitro. Trans. R Soc. Trop. Med. Hyg. 84, 507-5 1 0

    95. McLean, S.A., MacDougall, L.M. & Phillips, R.S. 1990. Early appearance of variant parasites in Plasmodium chabaudi infection. Parasite Immunol. 12, 97-103

    96. Brannan, L.R. & Phillips, R.S. 1990. Changes in antigenic type of cloned Plasmodium chabaudi populations. Trans. R. Soc. Trop. Med. Hyg. 84, 892

    97. Taylor-Robinson, A.W. & Phillips, R.S. 1990. Dichotomy of the L3T4+ T cell response to Plasmodium chabaudi. Trans. R. Soc. Trop. Med. Hyg. 84, 896

    98. Brannan, L.S., McLean, S.A., MacDougall, L.N. & Phillips, R.S. 1990. Antigenic variation in Plasmodium chabaudi demonstrated by an indirect fluorescent antibody test. Trans. R. Soc. Trop. Med. Hyg. 84, 166-167

    99. MacDougall, L.N., McLean,,S.A., Brannan, L.R. & Phillips, R.S. 1990. The role of the adherent spleen cell population in the immune response to Plasmodium chabaudi. Trans. R. Soc.Trop. Med. Hyg. 84, 170

    100. Taylor-Robinson, A.W. & Phillips, R.S. 1990. Investigation of primed spleen cell subpopulations in immunity to Plasmodium chabaudi. Trans. R. Soc.Trop. Med. ffyg 84, 172

    101. Ben Musa, N. & Phillips, R.S. 1991. The adaptation of three isolates of Babesia divergens to continuous culture in rat erythrocytes. Parasitology 103, 165-170

    102. Brannan, L.S., Khan, S. & Phillips, R.S. 1991. Plasmodium chabaudi: a comparison of antigenic variants in vivo and in vitro. Trans. R. Soc.Trop. Med. Hyg 85, 838

    103. Phillips, R.S. 1992. Vaccination against malaria. Immunobiology 184, 240-262

    104. Taylor-Robinson, A.W. & Phillips, R.S. 1992. Functional characterization of protective CD4+ T cell clones reactive to the murine malaria parasite Plasmodium chabaudi. Immunology 77, 99-105

    105. Taylor-Robinson, A.W. & Phillips, R.S. 1993. Antilmalarial antibodies in twins. Parasitology Today 9, 1-3

    106. Brannan, L.R., McLean, S.A. & Phillips, R.S. 1993. Antigenic variants of Plasmodium chabaudi chabaudi and the effect of mosquito transmission. Parasite Immunol. 15, 135-141

    107. Taylor-Robinson, A.W. & Phillips, R.S. 1993. Protective CD4+ T cell lines against Plasmodium chabaudi chabaudi show characteristics of either Th I or Th2 cells. Parasite Immunol. 15, 301-310.

    108. Taylor-Robinson, A.W. & Phillips, R.S. 1993. Differential Giemsa's staining of murine reticulocytes and its application to studies of malaria infection. Med. Sci. Res. 21, 697- 699

    109. Taylor-Robinson, Phillips, R.S., Sevem. A., Moncada, S. & Liew, F.Y. 1993. The role of Th I and Th2 cells in a rodent malaria system. Science 260, 1931-1934

    110. Mathers, K.E. & Phillips, R.S. 1993. Adoptive transfer of immunity to Plasmodium chabaudi CB with splenic T lymphocytes. Trans. R. Soc. Trop. Med. Hyg. 87, 121-122

    111. Brannan, L.R., Neuville, P. & Phillips, R.S. 1993. Characterization of Plasmodium chabaudi variant antigens. Trans. R. Soc. Trop. Med. Hyg. 87, 118

    112. Taylor-Robinson, A.W. & Phillips, R.S. 1993. CD4+ T cell clones provides protection against blood stage Plasmodium chabaudi infection. Trans. R. Soc. Trop. Med. Hyg. 87, 124

    113. Taylor-Robinson, A.W. & Phillips, R.S. 1994. Thl and Th2 CD4+ T cell clones specific for Plasmodium chabaudi but not for an unrelated antigen protect against blood stage P. chabaudi infection. Eur. J. Immunol. 24, 158-164

    114. Taylor-Robinson, A.W. & Phillips, R.S. 1994. Expression of the IL- I receptor discriminates Th2 from Th I cloned CD4+ T cells specific for Plasmodium chabaudi. Immunology, 81, 216- 221

    115. Brannan, L.R., Turner, C.M.R. & Phillips, R.S. 1994 Malaria parasites undergo antigenic variation at high rates in vitro. Proe. Roy. Soc. Ser. B. 256, 71-75

    116. Taylor-Robinson, A.W., Liew, F.Y., Severn, A., Damo, X., McSorley, S.J.k, Garside, P. Padron, J. & Phillips, R.S. Regulation of the immune response by nitric oxide differentially produced by Th I and Th2 cells. Eur. J. Immunol. 24, 980-988

    117. Taylor-Robinson, A.W. & Phillips, R.S. 1994. Predominance of infected reticulocytes in the peripheral blood of CD4+ T cell depleted mice chronically infected with Plasmodium chabaudi chabaudi. Parasitol Research. 80, 614-619.

    118. Phillips, R.S., Mathers, K.E. & Taylor-Robinson, A.W. 1994. T cells in immunity to Plasmodium chabaudi chabaudi: operation and regulation of different pathways of protection. Res.in Immunol. 145, 406-412

    119. Phillips, R.S. 1994 Malaria vaccines: a problem solved or simply a promising start? Protozoological Abstracts. 18, 459-486

    120. Phillips, R.S. 1994. Effector mechanisms against asexual erythrocytic stages of Plasmodium Immunology Letters. 41, 109-114

    121. Taylor-Robinson, A.W. & Phillips, R.S. 1994. B cells are required for the switch from Thl to Th2 regulated immune responses to Plasmodium chabaudi infection. Infect. Immun. 42, 2490-2498

    122. Taylor-Robinson, A.W., Phillips, R.S., Liew, F.Y., Clark A. & Owen, M. 1994. (XP but not y8T cells contribute to protective immunity to blood stage Plasmodium chabaudi infections. Trans. R. Soc. Trop. Med. Hyg. 88, 505-506

    123. Balmer, P., Phillips, H.M., Phillips, R.S., Maestre, A.E. & MeMonagle, F.A. 1995. The effects of SNAP, as a nitric oxide donor, on malaria parasites in vitro . Trans. R. Soc. Trop. Med. & Hyg. 89, 588

    124. Liew, F.Y., Taylor-Robinson, A.W. & Phillips, R.S. 1995. Biological implications of NO synthesis by T lymphocytes. In 'The Biology of Nitric Oxide'. Portland Press. vol 4, 320-322.

    125. Phillips, R.S. 1995. Antigenic variation in malaria: an appreciation of Neil Brown. TRP3 2, 14- 16

    126. Taylor-Robinson, A.W. & Phillips, R.S. 1995. Antigenic variation of malaria parasites in immunologically compromised hosts. Trans. R. Soc. Trop. Med. & Hyg. 89, 594

    127. Taylor-Robinson, A.W. & Phillips, R.S. 1996. Reconstitution of B cell-depleted mice with B cells restores Th2-type immune responses during Plasmodium chabaudi chabaudi infection. Infect. Irnrnun 64, 366-370.

    128. Taylor-Robinson, A.W., Sevem, A. & Phillips, R.S. 1996. Kinetics of nitric oxide production during infection and reinfection of mice with Plasmodium chabaudi. Parasite Immunol 18, 425-430

    129. Balmer, P., Mathers, K.E., Davidson, C. & Phillips, R.S. 1996. Chloroquine inhibition of nitric oxide production by macrophages. Annls. Trop. Med. & Parasitol. 90, 427

    130. Maestre, A.E., Liew, F.Y. & Phillips, R.S. 1996. Effect of oral inoculation with Salmonella typhimurium mutant carrying the murine interferony or tumour necrosis factor (x genes, on Plasmodium chabaudi infection. Annls. Trop. Med. & Parasitol. 90, 452

    131. Taylor-Robinson, A.W. & Phillips, R.S. 1996. Plasmodium chabaudi: the major antigenic type remains unchanged in an in vivo model deficient in B cells or Th2 cells. Annls. Trop. Med. & Parasitol. 90, 453-454

    132. Slater, L.A., McMonagle, F.A., McRobert, L. Ross, W., Robins, D. & Phillips, R.S. 1996 Antimalarial activity of some putrescine analogues. Trans. R. Soc. Trop. Med. Hyg. 90, 455

    133. Perrow, K., McMonagle, F.A., Strong, R.H. & Phillips, R.S. 1996. Antimalarial activity of extracts of the seeds of the neem tree: use of cyclodextrins as an effective solvent. Trans. R. Soc. Trop. Med. Hyg. 90,455

    134. Balmer, P., Phillips, R.S. 1996. The liver in the immune response to the asexual erythrocytic stages of Plasmodium chabaudi. Trans. R. Soc. Trop. Med. Hyg. 90, 452

    135. Balmer, P., Alexander, J. Bluethmann, H. & Phillips, R.S. 1997. Course of Plasmodium chabaudi As infection in IL-6 deficient mice. Trans. R. Soc. Trop. Med. Hyg. 91, 505

    136. Balmer, P. & Phillips, R.S. 1997. The role of serum amyloid P during Plasmodium chabaudi as infection. Trans. R. Soc. Trop. Med. Hyg. 91, 505

    137. Taylor-Robinson, A.W. & Phillips, R.S. Restoration of switch from Thl-Th2 type immune response during Plasmodium chabaudi infection in anti--treated mice following B cell reconstruction. Eur. J. Trop. Med. (abstract)

    138. Phillips, R.S., Brannan, L.R., Balmer, P. & Neuville, P. 1997. Antigenic variation during malaria infection - the contribution from the murine parasite Plasmodium chabaudi. Parasite Immunology 19,427-434.

    139. Phillips, R.S 1997. A multi-pronged attack on malaria. Parasitology Today. 13, 324-328

    140. Taylor-Robinson, A.W. & Phillips, R.S. 1998. Effect of antigen load on the regulation of immunity to the rodent malaria Plasmodium chabaudi. The Immunologist. (abstract).

    141. Taylor-Robinson, A.W. & Phillips, R.S. 1998. Infective dose modulates the balance between Th1- and Th2-regulated immune responses during blood-stage malaria infection. Scand. J. Immunol. 48, 527-534

    142. Slater, L.A., McMonagle, F.A., Phillips, R.S. & Robins, D.J. 1998. Antimalarial activity of unsaturated putrescine derivatives. Annls. Trop. Med. Parasitol. 92, 271-277

    143. Balmer, P., Alexander, J. & Phillips, R.S. 2000. Protective immunity to erythrocytic Plasmodium chabaudi AS infection involves IFN gamma-mediated responses and a cellular infiltrate to the liver. Parasitology 121, 473-482

    144. Phillips, R.S. 2001. Current status of malaria and potential for control. Clin. Micro. Rev. 14, 208-226

    145. Janssen, C.S., Barrett, M.P., Lawson, D., Quail, M.A., Harris, D., Bowman, S., Phillips, R.S. & Turner, C.M.R. 2001. Gene discovery in Plasmodium chabaudi by genome survey sequencing. Mol. Biochem. Parasitol. 113, 251-260

    146. Phillips, R.S. 2002. Malaria. Biological. Sciences 15, 29-33

    147. Janssen, C.S., Barrett, M.P., Turner, C.M. & Phillips, R.S. 2002. A large gene family for putative variant antigens shared by human and rodent malaria parasites. Proc. R. Soc. Lond. B Biol. Sci., 269, 431-436

    148. Daneshvar, H., Hagan, P. & Phillips, R. S. 2003. Leishmania mexicana H-line attenuated under pressure of gentamicin, potentiates a Th1 response and control of cutaneous leishmaniasis in BALB/c mice. Parasite Immunol. 25, 589-596

    149. Daneshvar, H., Coombs, G. H., Hagan, P.& Phillips, R. S. 2003. Leishmania mexicana and Leishmania major: Attenuation of wild-type parasites and vaccination with the attenuated lines. J. Infect. Dis. 187, 1662-1668

    150. Clark, C.J., Phillips, R.S. & Stone, T.W. 2003. Neuropeptide-containing cells in the cortex and striatum of mice with cerebral malaria. Adv. Exp. Med. Biol. 527, 347-356

    151. Quihui-Cota, L., Valencia, M. E., Crompton, D. W. T., Phillips, S., Hagan, P., Diaz-
    i. Camacho, S. P. & Tejas, A. T. 2004. Prevalence and intensity of intestinal parasitic infections in relation to nutritional status in Mexican schoolchildren. Trans. R. Soc. Trop. Med. Hyg. 98, 653-659

    152. Janssen, C. S., Phillips, R. S., Turner, C. M. R. & Barrett, M. P. 2004. Plasmodium
    i. interspersed repeats: the major multigene superfamily of malaria parasites. Nucl.
    ii. Acids Res. 32, 5712-5720

    153. Clark, C. J., Phillips, R. S., McMillan, R. B., Montgomery, I. O. & Stone, T. W. 2005. Differences in the neurochemical characteristics of the cortex and striatum of mice with cerebral malaria. Parasitol. 130, 23-29

    154. Clark, C. J., Mac Kay, G. M., Smythe, G. A., Bustamante, S., Stone, T. W., & Phillips, R. S. 2005. Prolonged survival of a murine model of cerebral malaria by kynurenine pathway inhibition. Infect. Immun. 73, 5249-5251

    155. Couper, K. N., Phillips, R. S., Brombacher, F. & Alexander, J. 2005. Parasite-specific IgM plays a significant role in the protective immune response to asexual erythrocytic stage Plasmodium chabaudi AS infection Parasite Immunol. 27, 171-180


    156. Seow, F., Sato, S., Janssen, C. S., Riehle, M. O., Mukhopadhyay, A., Phillips, R. S., Wilson, R. J. M., & Barrett, M. P. 2005. The plastidic DNA replication enzyme complex of Plasmodium falciparum. Mol. Biochem. Parasitol 141, 145-153

    157. Millington, O. R., Di Lorenzo, C., Phillips, R. S., Garside, P., & Brewer, J. 2006. Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of
    158. dendritic cell function J. Biol. 5, 1-22

    159. Quihui, L., Valencia, M.E, Crompton, D.W.T.Crompton, Phillips, R.S., Hagan, P., Morales, G., & Diaz-Camacho, S.P. 2006 Role of the employment status and education of mothers in the prevalence of
    160. intestinal parasitic infections in Mexican rural schoolchildren. BMC Public Health 6, 225-233.

    161. Owain R. Millington, Vivienne B. Gibson, Catherine M. Rush, Bernd H. Zinselmeyer, R. Stephen Phillips, Paul Garside & James M. Brewer 2007. Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PloS Pathogens - in press.