Dr. Chang-Phone Fung, Adjunct Associate Professor

Institute of Tropical Medicine, National Yang-Ming University (NYMU)

Education:

MSc in Clinical Microbiology, The London Hospital Medical College, University of London
MD, National Taiwan University

Experience¡G

2005/05 ~Present Deputy Superintendent, Chutung Veterans General Hospital
2006/01 ~Present Associate Professor, Institute of Tropical Medicine, NationalYang-Ming University
2003/01 ~ Present Associate Investigator, National Health Research Institute
2002/08 ~ 2005/12 Associate Professor, Faculty of Medicine, National Yang-Ming University
1998/01 ~ 2003/12 Managing Editor, Journal of Microbiology, Immunology and Infection
1997/01 ~ 1999/12 Secretary General, The Infectious Diseases Society of Republic of China
1989/01 ~ Present Attending Physician, Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital
1989/12 ~ 2002/07 Lecturer, Department of Medicine, National Yang-Ming University
1986/07 ~ 1987/06 Chief Resident, Department of Medicine, Taipei Veterans General Hospital
1982/06 ~ 1986/06 Resident, Department of Medicine, Taipei Veterans General Hospital

Research interests¡G

  1. Infectious Diseases
  2. Clinical Microbiology and Pathogenesis
  3. Molecular Microbiology
  4. Antibiotic resistance
  5. Nosocomial Infections

Publication list¡G(*Corresponding author)

  1. Yu WL, Ko WC, Cheng KC, Lee HC, Ke DS, Lee CC, Fung CP, Chuang YC.Association between rmpA and magA Genes and Clinical Syndromes Caused by Klebsiella pneumoniae in Taiwan. Clin Infect Dis. 2006;42:1351-8.
  2. Chi CY, Lai CH, Fung CP, Wang JH. Pseudomonas mendocina spondylodiscitis: a case report and literature review. Scand J Infect Dis. 2005;37:950-3.
  3. Chen TL, Thien PF, Liaw SC, Fung CP, Siu LK. First report of Salmonella enterica serotype panama meningitis associated with consumption of contaminated breast milk by a neonate. J Clin Microbiol. 2005;43:5400-2.
  4. Chen HP, Lai CH, Chan YJ, Chen TL, Liu CY, Fung CP*, Liu CY.Clinical significance of Acinetobacter species isolated from cerebrospinal fluid. Scand J Infect Dis. 2005;37:669-75.
  5. Chen HP, Chen TL, Lai CH, Fung CP*, Wong WW, Yu KW, Liu CY.Predictors of mortality in Acinetobacter baumannii bacteremia. J Microbiol Immunol Infect. 2005;38:127-36.
  6. Liu CY, Huang LJ, Lai CH, Chen HP, Chen TL, Fung CP, Liu CY. Clinical characteristics, management and prognostic factors in patients with probable severe acute respiratory syndrome (SARS) in a SARS center in Taiwan. J Chin Med Assoc. 2005;68:110-7.
  7. Lai CH, Chen HP, Chen TL, Fung CP*, Liu CY, Lee SD. Candidal liver abscesses and cholecystitis in a 37-year-old patient without underlying malignancy. World J Gastroenterol. 2005 ;11:1725-7.
  8. Ma L, Chang FY, Fung CP, Chen TL, Lin JC, Lu PL, Huang LY, Chang JC, Siu LK.Variety of TEM-, SHV-, and CTX-M-type beta-lactamases present in recent clinical isolates of Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae from Taiwan. Microb Drug Resist. 2005;11:31-9.
  9. Fung CP, Hsieh TL, Tan KH, Loh CH, Wu JS, Li CC, Chang FY, Siu LK, Yen MY, Wang LS, Wong WW, Kao WF, Hsu JH, Lin TH, Huang FY, Lee CH.Rapid creation of a temporary isolation ward for patients with severe acute respiratory syndrome in Taiwan. Infect Control Hosp Epidemiol. 2004;25:1026-32.
  10. Lai CH, Chi CY, Chen HP, Chen TL, Lai CJ, Fung CP*, Yu KW, Wong WW, Liu CY. Clinical characteristics and prognostic factors of patients with Stenotrophomonas maltophilia bacteremia. J Microbiol Immunol Infect. 2004;37:350-8.
  11. Lai CH, Chi CY, Chen HP, Lai CJ, Fung CP*, Liu CY. Port-A catheter-associated Nocardia bacteremia detected by gallium inflammation scan: a case report and literature review. Scand J Infect Dis. 2004;36:775-7.
  12. Liu CE, Chen CH, Hsiao JH, Young TG, Tsay RW, Fung CP. Drug resistance of Mycobacterium tuberculosis complex in central Taiwan. J Microbiol Immunol Infect. 2004;37:295-300.
  13. Lin JC, Chang FY, Fung CP, Xu JZ, Cheng HP, Wang JJ, Huang LY, Siu LK. High prevalence of phagocytic-resistant capsular serotypes of Klebsiella pneumoniae in liver abscess. Microbes Infect. 2004;6:1191-8.
  14. Chen TL, Chen HP, Fung CP*, Lin MY, Yu KW, Liu CY. Clinical characteristics, treatment and prognostic factors of candidal meningitis in a teaching hospital in Taiwan. Scand J Infect Dis 2004;36:124-30.
  15. Chi CY, Wong WW, Fung CP*, Yu KW, Liu CY. Epidemiology of community-acquired Staphylococcus aureus bacteremia. J Microbiol Immunol Infect. 2004 ;37:16-23.
  16. Chi CY, Fung CP*, Wong WW, Liu CY. Brevundimonas bacteremia: two case reports and literature review. Scand J Infect Dis. 2004;36:59-61.
  17. Chen JY, Fung CP, Chang FY, Huang LY, Chang JC, Siu LK. Mutations of the rpoB gene in rifampicin-resistant Streptococcus pneumoniae in Taiwan. J Antimicrob Chemother. 2004;53:375-8.
  18. Chen TL, Chan CC, Chen HP, Fung CP*, Lin CP, Chan WL, Liu CY. Clinical characteristics and endoscopic findings associated with Blastocystis hominis in healthy adults. Am J Trop Med Hyg. 2003;69:213-6.
  19. Chen JY, Fung CP, Wang CC, Chu ML, Siu LK. In vitro susceptibility of six fluoroquinolones against invasive Streptococcus pneumoniae isolated from 1996 to 2001 in Taiwan. Microb Drug Resist. 2003;9:211-7.
  20. Chen TL, Tsai CA, Fung CP*, Lin MY, Yu KW, Liu CY. Clinical significance of Candida species isolated from cerebrospinal fluid. J Microbiol Immunol Infect. 2002;35:249-54.
  21. Fung CP, Chang FY, Lee SC, Hu BS, Kuo BIT, Liu CY, et al. A global emerging disease of Klebsiella pneumoniae liver abscess: is serotype K1 an important factor for complicated endophthalmitis? Gut 2002;50:420-4.
  22. Fung CP, Ho MW, Wang FD, Tsai K, Liu CE, Liu CY, et al. Combined use of automated ribotyping, RAPD and PFGE for investigation of methicillin-resistant Staphylococcus aureus outbreak in a cardiovascular surgery unit. APMIS 2001;109:474-80.
  23. Fung CP, Hu BS, Chang FY, Lee SC, Kuo BI, Ho M, et al. A 5-year study of theseroepidemiology of Klebsiella pneumoniae: high prevalence of capsular serotype K1 in Taiwan and implication for vaccine efficacy. J Infect Dis 2000;181:2075-9.
  24. Fung CP, Lee YM, Kuo BI, Yang SP, Chan YJ, Liu CY, et al. Using buffy coat for reverse transcriptase-polymerase chain reaction in the diagnosis of dengue virus infection: preliminary study. J Microbiol Immunol Infect 2000 ;33:217-22.
  25. Fung CP, Hu BS, Lee SC, Liu PY, Jang TN, Leu HS, et al. Antimicrobial resistance of Streptococcus pneumoniae isolated in Taiwan: an island-wide surveillance study between 1996 and 1997. J Antimicrob Chemother 2000;45:49-55.
  26. Tsay RW, Siu LK, Fung CP, Chang FY. Characteristics of bacteremia between community-acquired and nosocomial Klebsiella pneumoniae infection: risk factor for mortality and the impact of casular serotypes as a herald for community-acquired infection. Arch Intern Med 2002;162: 1021-7.
  27. Cheng HP, Chang FY, Fung CP, Siu LK. Klebsiella pneumoniae liver abscess in Taiwan is not caused by a clonal spread strain. J Microbiol Immunol Infect 2002;35:85-8.
  28. Chang FY, Siu LK, Fung CP, Huang MH, Ho M. Diversity of SHV- and TEM- -lactamase producing Klebsiella pneumoniae implication of gene evoluation in northern Taiwan and two novel -lactamase SHV-25 and SHV-26. Antimicrob Agents Chemother 2001;45:2407-13.
  29. Lee SC, Fung CP, Lee N, See LC, Huang JS, Tsai CJ, et al. Fluconazole disk diffusion test with methylene blue- and glucose-enriched M agar for determining susceptibility of Candida species. J Clin Microbiol 2001;39:1615-7.
  30. Jang TN, Fung CP, Yang TL, Shen SH, Huang CS, Lee SH. Use of pulsed-field gel electrophoresis to investigate an outbreak of Serratia infection in a neonatal intensive care unit. J Hosp Infect 2001;33:179-81.
  31. Yang SP, Yu KW, Liu CY, Fung CP, Wong WW, Wang FD, et al. Clinical characteristics of group G streptococcal bacteremia in Taiwan. Scand J Infect Dis 2001;33:179-81.
  32. Lee YM, Leu SY, Chiang H, Fung CP, Liu WT. Human papillomavirus type 18 in colorectal cancer. J Microbiol Immunol Infect 2001;34:87-91.
  33. Lee SC, Fung CP, Huang JS, Tsai CJ, Chen KS, Chen HY, et al.Clinical correlates of antifungal macrodilution susceptibility test results for non-AIDS patients with severe Candida infections treated with fluconazole. Antimicrob Agents Chemother 2000;44:2715-8
  34. Kuo BI, Fung CP, Liu CY. Meropenem versus imipenem/cilastatin in the treatment of sepsis in Chinese patients. Chung Hua i Hsueh Tsa Chih - Chinese Med J 2000;63:361-7.
  35. Chang SW, Yen DH, Fung CP, Liu CY, Chen KK, Tiu CM, et al. Klebsiella pneumoniae renal abscess. Chung Hua i Hsueh Tsa Chih - Chinese Med J 2000;63:721-8.
  36. Jang TN, Kuo BI, Shen SH, Fung CP, Lee SH, Yang TL, et al. Nosocomial gram-negative bacteremia in critically ill patients: epidemiologic characteristics and prognostic factors in 147 episodes. J Formos Med Assoc 1999;98:465-73.
  37. Hu BS, Fung CP, Lau YJ, Lin YH, Shi ZY. Antimicrobial susceptibility of clinical isolates of enterococci. J Microbiol Immunol Infect 1999;32:111-5.
  38. Lee SC, Fung CP, Liu PY, Wang TC, See LC, Lee N, et al.Nosocomial infections with ceftazidime-resistant Pseudomonas aeruginosa: risk factors and outcome. Infect Control Hosp Epidemiol 1999;20:205-7.
  39. Lee SC, Fung CP, Lin CC, Tsai CJ, Chen KS. Porphyromonas gingivalis bacteremia and subhepatic abscess after renal transplantation: a case report. J Microbiol Immunol Infect 1999;32:213-6.
  40. Liu CE, Wong WW, Yang SP, Wang FD, Fung CP et al. Flavobacterium meningosepticum bacteremia: an analysis of 16 cases. Chung Hua i Hsueh Tsa Chih - Chinese Med J 1999;62:125-32.
  41. Yang YY, Fung CP, Yu IT Chiang JH. Genital tuberculosis with peritonitis mimicking Meig's syndrome: a case report. J Microbiol Immunol Infect 1999;32:217-21.
  42. Cheng NC, Wong WW, Fung CP, Liu CY. Unusual pulmonary manifestations of disseminated Penicillium marneffei infection in three AIDS patients. Med Mycol 1998;36:429-32.
  43. Fung CP, Lee SC, Liu PY, Jang TN, Wong FD, Kuo BI, et al. beta-Lactam resistance and beta-lactamase isoforms of Moraxella catarrhalis isolates in Taiwan. J Formos Med Assoc 1998;97:453-7.
  44. Lee SC, Fung CP, Lee N Shieh WB. Cat-scratch disease caused by Bartonella henselae: the first case report in Taiwan. J Formos Med Assoc 1998;97:569-72.
  45. Lin SY, Wong WW, Fung CP, Liu CE, Liu CY. Acinetobacter calcoaceticus-baumannii complex bacteremia: analysis of 82 cases. J Microbiol Immunol Infect 1998;31:119-24.
  46. Liu PY, Hu BS, Fung CP, Lau YJ, Shi ZY, Lin YH. Molecular epidemiology of penicillin-resistant Streptococcus pneumoniae isolated in central Taiwan. Diagn Microbiol Infect Dis 1998;31:511-5.
  47. Tseng CY, Wang FD, Lee YJ, Fung CP, Liu CY. Pseudomonas mendocina bacteremia in an adult with cellulitis of the left upper extremities. J Microbiol Immunol Infect 1998;31:69-72.
  48. Wang YY, Lee FY, Chang FY, Lee SD, Fung CP. A vanishing liver abscess complicated with Klebsiella pneumoniae chest wall abscess: a case report. J Microbiol Immunol Infect 1998;31:249-52.
  49. Hu BS, Fung CP, Liu PY, Lau YJ, Shi ZY, Lin YH. In vitro antimicrobial activity of levofloxacin against Streptococcus pneumoniae. Chung Hua i Hsueh Tsa Chih - Chinese Med J 1997;60:191-4.
  50. Jang TN, Juang GD, Fung CP. Fulminating gas-forming psoas muscle abscess due to Klebsiella pneumoniae following a deep neck infection. J Formos Med Assoc 1997;96:134-6.
  51. Yeo SF, Chiew YF, Fung CP. Susceptibility of Haemophilus influenzae isolates with known resistance mechanisms to five cephalosporins. Chemotherapy 1996;42:85-9.
  52. Liu CY, Lee WS, Fung CP, Cheng NC, Liu CL, Yang SP, Chen SL. Comparative study of teicoplanin vs vancomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia. Clin Drug Invest 1996;12:80-7.
  53. Fung CP, Jang TN, Liu CY, Lau YJ, Liu YC, Chuang YC, et al. Antimicrobial susceptibility and beta-lactamase production of Moraxella catarrhalis isolates in Taiwan. J Formos Med Assoc 1995;94:548-54.
  54. Jang TN, Fung CP, Liu CY, Wang FD, Liu IM. Enterococcal meningitis: analysis of twelve cases. J Formos Med Assoc 1995;94:391-5.
  55. Jang TN, Fung CP. Treatment of pyogenic splenic abscess: nonsurgical procedures. J Formos Med Assoc 1995;94:309-12.
  56. Jang TN, Liu CY, Wang FD, Yang SP, Fung CP. A randomized comparative study on the safety and efficacy of clarithromycin and erythromycin in treating community-acquired pneumonia. Chung Hua i Hsueh Tsa Chih - Chinese Med J 1995;55:302-6.
  57. Fung CP, Yeo SF, Livermore DM. Susceptibility of Moraxella catarrhalis isolates to beta-lactam antibiotics in relation to beta-lactamase pattern. J Antimicrob Chemother 1994;33:215-22.
  58. Fung CP, Yeo SF, Livermore DM. Extraction of beta-lactamase from Moraxella catarrhalis . J Antimicrob Chemother 1994;34:183-4.
  59. Liu MT, Wong CK, Fung CP. Disseminated Penicillium marneffei infection with cutaneous lesions in an HIV-positive patient. Br J Dermatol 1994;131:280-3.
  60. Fung CP, Powell M, Seymour A, Yuan M, Williams JD. The antimicrobial susceptibility of Moraxella catarrhalis isolated in England and Scotland in 1991. J Antimicrob Chemother 1992;30:47-55.