Sun KH, Lin HY, Chen LW, Tai HY, Lin ML, Liu WT, 2003, Human foamy virus Bel1 sequence in patients with autoimmune diseases (submitted) Tang SJ, Sun KH, Sun GH, Chang TY, Wu WL, Lee GC, 2003, A transformation system for the nonuniversal CUG(Ser) codon usage species Candida rugosa. J Microbiol Methods 52:231-238. Sun KH, Tang SJ, Wang YS, Lin WJ, You RI, 2003, Autoantibodies to dsDNA cross-react with the arginine-glycine-rich domain of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) and promote methylation of hnRNP A2. Rheumatology 42:154-161. (Corresponding author) Yu CL, Yu HS, Sun KH, Hsieh SC, Tsai CY, 2002, Anti-CD45 isoform antibodies enhance phagocytosis and gene expression of IL-8 and TNF-a in human neutrophils by differential suppression on protein tyrosine phosphorylation and p56lck tyrosine kinase. Clin. Exp. Immunol. 129: 78-85. Hsieh SC, Sun KH, Tsai CY, Tsai YY, Tsai ST, Huang DF, Han SH, Yu HS, Yu CL, 2001, Monoclonal anti-double stranded DNA antibody is a leukocyte binding protein to up-regulate IL-8 gene expression and elicit apoptosis of normal human polymorphonuclear neutrophils. Rheumatology 40:851-858. Tai HY, Sun KH, Kung SH, Liu WT, 2001, A quantitative assay for measuring human foamy virus using an established indicator cell line. J Virological Methods 94:155-162. Sun KH, Tang SJ, Lin ML, Wang YS, Sun GH, Liu WT, 2001, Monoclonal antibodies against human ribosomal P proteins penetrate into living cells and cause apoptosis of Jurkat T cells in culture. Rheumatology (British J Rheumatol) 40:750-756. (Corresponding author) Tang SJ, Shaw JF, Sun KH, Sun GH, Chang TY, Lin CK, Lo YC, Lee GC, 2001, Recombinant expression and characterization of the Candida rugosa lip4 lipase in Pichia pastoris: Comparison of glycosylation, activity, and stability. Archives Biochem. Biophy. 387:93-98. Yu CL, Sun KH, Tsai CY, Hsieh SC, Yu HS. Anti-dsDNA antibody up-regulates interleukin 6, but not cyclooxygenase, gene expression in glomerular mesangial cells: a marker of immune-mediated renal damage? Inflammation Research 2001 50:12-8. Tang SJ, Sun KH, Sun GH, Chang TY, Lee GC, 2000, Recombinant expression of the Candida rugosa LIP4 lipase in Escherichia coli. Protein Expression Purification 20:308-313. Sun KH, Yu CL, Tang SJ, Sun GH, 2000, Monoclonal anti-double stranded-DNA autoantibody stimulates the expression and release of IL-1β, IL-6, IL-8, IL-10 and TNF-α from normal human mononuclear cells involving in the lupus pathogenesis. Immunology 99:352-360. (Corresponding author) Tang SJ, Sun KH, Sun GH, Lin G, Lin WW, Chuang MJ, 1999, Cold-induced ependymin expression in zebrafish and carp brain: Implication for cold acclimation. FEBS Letters 459:95-99. Lee GC, Tang SJ, Sun KH, Shaw JF, 1999, Analysis of the gene family encoding lipases in Candida rugosa by competitive reverse transcription-PCR. Applied Environmental Microbiology 65:3888-3895. Sun KH, Hong CC, Tang SJ, Sun GH, Liu WT, Han SH, Yu CL, 1999, Anti-dsDNA autoantibody cross-reacts with C-terminal hydrophobic cluster region containing phenylalanines in the acidic ribosomal phosphoprotein P1 to exert a cytostatic effect on the cells. Biochemical Biophysical Research Communications 263:334-339. (Corresponding author) Yu CL, Sun KH, Tsai CY, Tsai YY, Tsai ST, Huang DF, Han SH, Yu HS, 1998, Expression of Th1/Th2 cytokine mRNA in peritoneal exudative polymorphonuclear neutrophils and their effects on mononuclear cell Th1/Th2 cytokine production in MRL-lpr/lpr mice. Immunology 95:480-487. Yu CL, Huang MH, Kung YY, Tsai CY, Tsai YY, Tsai ST, Huang DF, Sun KH, Han SH, Yu HS, 1998, Interleukin-13 increases prostaglandin E2 (PGE2) production by normal human polymorphonuclear neutrophils by enhancing cyclooxygenase 2 (COX-2) gene expression. Inflamm Res 47:167-173. Yu CL, Huang MH, Tsai CY, Tsai ST, Sun KH, Han SH, Yu HS, 1998, The effect of human polyclonal anti-dsDNA autoantibodies on apoptotic gene expression in cultured rat glomerular mesangial cells. Scand J Rheumatol 27:54-60. Hsieh SC, Huang MH, Tsai CY, Tsai YY, Tsai ST, Sun KH, Yu HS, Han SH, Yu CL, 1997, The expression of genes modulating programmed cell death in normal human polymorphonuclear neutrophils. Biochem Biophys Research Commun 233: 700-706. Yu CL, Tsai CY, Sun KH, Hsieh SC, Tsai YY, Tsai ST, Yu HS, Han SH, 1997, Tamm-Horsfall glycoprotein (THG) is a binder for surface membrane proteins on blood cells and glomerular mesangial cells. Immunopharmacology 35:237-245. Yu CL, Huang MH, Tsai CY, Sun KH, Hsieh SC, Tsai YY, Tsai ST, Yu HS, Han SH, 1996, The reactivity of sera from patients with systemic lupus erythematosus to seven different species of single and double stranded deoxyribonucleic acids. Clin Exp Rheumatol 14:137-144. Sun KH, Liu WT, Tang SJ, Tsai CY, Hsieh SC, Wu TH, Han SH, Yu CL, 1996,The expression of acidic ribosomal phosphoproteins on the surface membrane of different tissues in autoimmune and normal mice which are the target molecules for anti-dsDNA antibodies. Immunology 87:362-371. Sun KH, 1995, The study on the molecular mechanism of anti-dsDNA antibodies-induced glomerular mesangial cell damage -- Acidic ribosomal P proteins as possible targets for the autoantibodies. Ph.D. Dissertation. Sun KH, Liu WT, Tsai CY, Tang SJ, Han SH, Yu CL, 1995, Anti-dsDNA antibodies cross-react with ribosomal P proteins expressed on the surface of glomerular mesangial cells to exert a cytostatic effect. Immunology 85:262-269. Hsieh SC, Tsai CY, Sun KH, Tsai YY, Tsai ST, Han SH, Wu TH, Yu HS, Yu CL, 1995, Defective spontaneous and bacterial lipopolysaccharide stimulated production of interleukin-1 receptor antagonist by polymorphonuclear neutrophils of patients with active systemic lupus erythematosus. British J Rheumatol 34:107-112. Tsai CY, Wu TH, Huang SF, Sun KH, Hsieh SC, Han SH, Yu HS, Yu CL, 1995, Abnormal splenic and thymic IL-4 and TNF-α expression in MRL-lpr/lpr mice. Scand J Immunol 41:157-163. Liu WT, Lee TS, Sun KH, Twu SJ, Shi CH, Wang GR, 1994, The measurement for mRNA level of tumor necrosis factor-alpha from human immunodeficiency virus seropositive individuals. J Biomed Lab Sci 6:171-176. Hsieh SC, Tsai CY, Sun KH, Yu HS, Tsai ST, Wang JC, Tsai YY, Han SH, Yu CL, 1994, Decreased spontaneous and lipopolysaccharide stimulated production of IL-8 by polymorphonuclear neutrophils of patients with active systemic lupus erythematosus. Clin Exp Rheumat 12:627-633. Yu CL, Sun KH, Shei SC, Tsai CY, Tsai ST, Wang JC, Liao TS, Lin WM, Chen HL, Yu HS, Han SH, 1994, Interleukin 8 modulates interleukin-1β, and interleukin-6 and tumor necrosis facotr-α release from normal human mononuclear cells. Immunopharmacology 27:207-214. Yu CL, Liu CL, Tsai CY, Sun KH, Liao TS, Lin WM, Chen HL, Yu HS, 1993, Prostaglandin E2 suppresses phytohemagglutinin-induced immune responses of normal human mononuclear cells by decreasing intracellular glutathione generation, but not due to a increased DNA breaks or apoptosis. Agents & Actions 40:191-199. Lieu CW, Liu WT, Sun KH, Wang SY, 1993, Some special characteristics of the novel human promonocyte cell line, HL-CZ. J Biomed Lab Sci 5:196-204. Yu CL, Tsai CY, Lin WM, Liao TS, Chen HL, Sun KH, Chen KH, 1993, Tamm-Horsfall urinary glycoprotein enhances monokine release and augments lymphocyte proliferation. Immunopharmacology 26:249-258. Tsai CY, Wu TH, Sun KH, Liao TS, Lin WM, Yu CL, 1993, Polyclonal IgG anti-dsDNA antibodies exert cytotoxic effect on cultured rat mesangial cells binding to the cell membrane and augmenting apoptosis. Scand J Rheumatol 22:162-171. Yu CL, Lin WM, Liao TS, Tsai CY, Sun KH, Chen KH, 1992, Tamm-Horsfall glycoprotein (THG) purified from normal human pregnancy urine increases phagocytosis, complement receptor expressions and arachidonic acid metabolism of polymorphonuclearneutrophils. Immunopharmacology 24:181-190. Sun KH, Liu WT, Tsai CY, Liao TS, Lin WM, Yu CL, 1992, Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum. Annal Rheumatic Diseases 51:707-712. Yu CL, Tsai CY, Sun KH, Chen YS, Lin WM, Liao TS, Chen KH, Wang SR, 1992, Increased spontaneous release of cytidine deaminase by polymorphonuclear neutrophils of patients with active systemic lupus erythematosus. British J Rheumatol 31:675-678. Tsai CY, Wu TH, Sun KH, Yu CL, 1992, Effect of antibodies to double stranded DNA, purified from serum samples of patients with active systemic lupus erythematosus, on the glomerular mesangial cells. Annal Rheumatic Diseases 51:162-167. Tsai CY, Wu TH, Sun KH, Lin WM, Yu CL, 1992, Increased excretion of soluble interleukin-2 receptors and free light chain immunoglobulins in the urines of patients with active lupus nephritis. Annual Rheumatic Diseases 51:168-172. Yu CL, Sun KH, Tsai CY, Wang SR, 1991, Inhibitory effects of anticardiolipin antibodies on lymphocyte proliferation and neutrophil phagocytosis. Annal Rheumatic Diseases 50:903-908.
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