Objective and Mission


The educational objective of the institute of microbiology and immunology is to cultivate first-class talents in research and education.

It endeavors
to acquaint students to all fields of life sciences,
to familiarize students with advancing frontiers in the life sciences,
to teach students analytic and deductive abilities,
to enable students to organize human and material resources
to design experiments to independently finish high-quality research, and
to communicate them effectively to professionals and non-professionals

The institute also endeavors
to cultivate talents for biomedical industry,
to comply with government's efforts to promote academic-industrial cooperation, to help with international certification,
to promote extension education program ,
to elevate standards in bacterial and viral diagnostic techniques on therapeutics, food, and cosmetics.



History of Microbiology & Immunology institute


Department of Microbiology founded in 1977.

Graduate Institute of Microbiology and Immunology founded in 1981. Ph.D. program started in 1984.

Set up Program of Molecular Medicine in 2003, in collaboration with Academia Sinica.

Faculty of the Dept. & Institute of Microbiology:
@Full-time professors, 5;@Emeritus professor, 1;
@Associate Professor, 1;@Assistant Professor, 2;
@Teaching assistants, 3;@Technician, 1;
@Adjunct Professors, 19.



Research activities


Bacteriology

The molecular biology of prokaryotic transposons.
Discovery and biology of Hyperthermophlic Archaea.
Diagnosis and biology of clinically important bacteria.
Epidemiology, drug Resistance, and pathogenicity of pathogens and Enterohemorrhagic E. coli.
Taxonomy and genetics of bacteria.
Membrane translocation mechanism of colicins of E. coli.

Immunology

Immunobiology of dendritic cells
@-Innate immunity receptors
@@* C-type lectin
@@* TREM receptor
@@* TREM-like receptor
@-Immunotherapy
Cancer Immunotherapy
Inflammatory Cytokines: TNF, Chemokines
Structure and activation mechanisms of T cell receptors.
Regulation of immune T Cell.

Virology

Hepatitis virus B
@-Pathogenesis
@-Replication
@-Regulation
@of gene expression
Epstein-Barr virus/KSHV
@-Function of viral proteins
@-Regulation of gene expression
@-Virus and host interaction
@-Implication in tumorigenesis
Dengue virus and SARS virus
@-Function of viral Proteins,
@-Virus and host interaction.

Molecular Cell Biology

Regulation of DNA replication, molecular mechanisms of transcription, splicing and translation.
Signal transduction and cell cycle regulation by cytokines and tumor-promoting factors.
Stem cells differentiation, and Apoptosis.
Nucleolar structural dynamics.
Identification of functions of novel liver cancer-related genes.
Protein sorting in polarized epithelia



Facility and Equipment


Fluorescence activated cell sorter
Confocal microscope & Other bioimaging tools
French Press



Future outlook in educational plan and / or research development


In the educational front, the department and institute endeavor to assist the reform initiative in medical education inaugurated by the Medical School. This initiative emphasizes problem-based learning and aims to improve students' ability to self learning.

In the research front, the department and the institute endeavors to focus on bacterial and viral pathogens and the host-defense mechanisms. The institute hopes to establish bacterial and viral research centers in order to coordinate researchers, to employ new biological techniques and to promote quality research publications.