Dr. Hsei-Wei Wang, Assistant Professor

Phone: 886-2-2826-7109
E-mail: hwwang@ym.edu.tw
Educationˇ@Researchˇ@Publications


Education



Research

1. Viral Oncology (KSHV & Kaposi sarcoma; Lentivirus-based gene transfer/targeting)

2. Bioinformatics (Microarray & Statistics; Protein Modeling; Database construction)

3.Cell Biology (Stem cells; Lymphatic and blood vessel endothelial cells; Apoptosis)


Publications

1. Wang HW, Trotter MW, Lagos D, Bourboulia D, Henderson S, Makinen T, Elliman S, Flanagan AM, Alitalo K, Boshoff C. (2004) Epub 2004 Jun 27. Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat Genet. 2004 Jul;36(7):687-93. (PDF)

2. Wang HW, Sharp TV, Koumi A, Koentges G and Boshoff C. (2002) Characterization of an Antiapoptotic Glycoprotein Encoded by Kaposiˇ¦s Sarcoma-Associated Herpesvirus Which Resembles a Spliced Variant of Human Survivin. EMBO J. 21(11): 2602-2615. (PDF)

3. Sharp TV, Wang HW, Koumi A, Hollyman D, Endo Y, Ye H, Du MQ, Boshoff C. (2002) K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function. J. Virol. 76(2):802-16. (PDF)

4. Wang HW, Wu HL, Chen DS, and Chen PJ. (1997) Identification of the functional regions required for hepatitis D virus replication and transcription by linker-scanning mutagenesis of viral genome. Virology 8;239(1):119-31. (PDF)

5. Chia JS, Wu HL, Wang HW, Chen DS, and Chen PJ. (1997) Inhibition of Hepatitis Delta Virus Genomic Ribozyme Self-Cleavage by Aminoglycosides. J. Biomed. Sci. 4:208-216. (Abstract)

6. Wang HW, Chen PJ, Lee CZ, Wu HL, Chen DS. Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens. J Virol. 1994 Oct;68(10):6363-71. (PDF)


GenBank Sequences Submissions

1. AF229031 (Apr 2000)
ˇ@ˇ@Listeria monocytogenes RecA (recA) gene, complete cds

2. AF228345 (Mar 2000)
ˇ@ˇ@Listeria monocytogenes unknown gene

3. AF 242890 (Aug 2000)
ˇ@ˇ@Sagiyama virus envelope glycoprotein E1 gene, partial cds


Selected websites and journals discussed and commented on our research

Nature Reviews Cancer 2004, 4: 572 (PDF)

The Lancet, 2004, 364:740-741 (PDF)

UCLNews, Wed 14, July 2004 (Link)

http://news.bbc.co.uk/2/hi/health/3860167.stm

http://www.cancerpage.com/news/article.asp?id=7235

http://www.cancerresearchuk.org/news/pressreleases/cancertherapy_27jun04

http://www.news-medical.net/print_article.asp?id=2849

http://www.aidsmeds.com/news/20040628scie005.html

http://www.vidyya.com/vidyyav6i186.htm


Members of Laboratory

Master students