Alumni of Ph. D. Students

1989¡@1990¡@1991¡@1992¡@1993¡@1994¡@1995¡@1996
1997¡@1998¡@1999¡@2000¡@2001¡@2002¡@2003¡@2004   2005  2006

1989

Student¡@§º«CµØ
1984.9 - 1989.6
Professor¡@Chung-Ming Chang
Publications
1. Sung, C.-H., Hu, C., Hsu, H.-C., Ng, A.-K., Chou, C.-K., Ting, L.-P., Su, T.-S., Han, S.-H. and Chang, C.(1989). Expression of class I and class II major histocompatibility antigens on human hepatocellular carcinoma. J. Clin. Invest. 83:421-429.


1990

Student¡@±`ßN®Û
1985.9 - 1990.1
Professor¡@Ling-Pai Ting
Publications
1.Chang, H.-K., Wang, B.-Y., Yuh, C.-H., Wei, C.-L. and Ting, L.-P. (1989). A liver-specific nuclear factor interacts with the promoter region of the large surface protein gene of human hepatitis B virus. Mol. Cell. Biol. 9: 5189-5197.
2.Chang, H.-K. and Ting, L.-P. (1989). The surface gene promoter of the human Hepatitis B virus displays a preference for differentiated hepatocytes.Virology. 170:176-183.
3.Ting, L.-P., Jeng, K.-S., Chou, C.-K., Su, T.-S., Hu, C.-P., Wong, F.-H., Chang, H.-K. and Chang, C. (1988). Expression of oncogenes in human hepatoma cell lines. Chinese J. Microbiol. Immunol. 21:141-150.
4.Chang, H.-K., Chou, C.-K., Chang, C., Su, T.-S., Hu, C., Yoshida, M. and Ting, L.-P. (1987). The enhancer sequence of human hepatitis B virus can enhance the activity of its surface gene promoter. Nucleic. Acid Res. 15:2261-2268.
5.Ting, L.-P. and Chang, H.-K. (1987). Characterization of nucleotide sequence of hepatitis B surface gene and enhancer element of HBV. Chinese J. Microbiol. Immunol. 20:224-240.
6.Ting, L.-P., Chang, H.-K. and Chiang, C.-S. (1986) Expression of hepatitis B surface antigen by yeast actin gene promoter. Biochem. Biophy. Res. Commun. 136:1063-1070.

Student¡@³¢¨|ºö
1984.9 - 1990.5
Professor¡@Ching-Yuang Lin
Publications
1.Kuo, Y.-C., Lin, C.-Y., Cheng, S.-F., Lin, C.-C. and Liu, W.-T. (1986). National killer cell activity. I. normal range of natural killer cell activity in the Chinese population. Chinese J. Micribol. and Immunolo. 19:112-117.
2.Kuo, Y.-C., Lin, C.-Y., Cheng, C.-F., Lin, C.-C. and Liu, W.-T. (1987). Impaired natural killer cell cytotoxicity during recrudescence of recurrent herpes simplex virus type 2 infection. Cancer Detection and Prevention. 1:51-55.
3.Lin, C.-C., Kuo, Y.-C., Huang, W.-C. and Lin, C.-Y. (1987). The activity of natural killer cell activity in patients of lung cancer. Chest. 92:1022-1024.
4.Lee, B.-H., Kuo, Y.-C., Lin, C.-Y. (1987). Impaired interleukin-2, gamma-interferon production nd natural killer cytotoxicity in active systemic lupus erythematosus patients. Acta aediatrica Sinica. 28:412-419.
5.Lin, C.-Y., Kuo, Y.-C., Lin, C.-C. and Ou, B.-R. (1988). Enhancement of interleukin-2, gamma- interferon production in vitro on cord blood lymphocytes and in vivo on primary cellular immunodeficiency patients with thymic extract (Thumostimulin). J. Cli. Immnol. 8:103-107.
6.Kuo, Y.-C. and Lin, C.-Y. (1990). Recurrent herpes simplex virus type 1 infection precipitated by impaired production of interleukin-2, alpha-interferon, and cell mediated cytotoxicity. J. Med. Virol. 31:183-189.

Student¡@´¿´f¤¤
1984.6 - 1990.6
Professor¡@Carton Wen-sheng Chen
Publications
1.Tseng, H.-C., Chen, C.-W., Lin, K., Hsu, B.-J., Leu, W.-M., and Lee-Wu, Y.-H. (1991). A cloned ompR-like gene of Streptomyces lividas 66 suppresses defective melCl, a putative copper-transfer gene. Mol. Microbiol. 5:1187-1196.
2.Tseng, H.-C., Lin, C.-K., Hsu, B.-J., Leu, W.-M., Lee-Wu, Y.-H., Chiou, S.-J. Hu, N.-T. and Chen, C.-W. (1990). The melanin operon of Streptomyces antibiotics: expression and use as a marker in Gram-negative bacteria. Gene. 86: 123-128.
3.Tseng, H.-C. and Chen., C.-W. (1991). A cloned ompR-like gene of Streptomyces lividans 66 suppresses defective melCl, a putative copper-transfer gene. Mol. Microbiol. 5:1187-1196.


1991

Student¡@§õÄõ·ë
1987.9 - 1991.5
Professor¡@Shih-Tung Liu
Publications
1.Lee, L.-Y. and Liu, S.-T. (1991). Characterization of the yellow pigment genes of Erwinia herbicola. Mol. Microbiol. 5:217-224 .
2.Liu, S.-T., Lee, L.-Y., Tai, C.-Y., Hung, C.-H., Chang, Y.-S., Wolfram J.-H., Rogers, R., and Glodstein, A.-H. (1992). Cloning of an Erwinia herbiocola gene necessary for gluconic acid production and enhanced mineral phosphate solubilization in Escherichia coli HB101: Nucleotide sequence and probable involvement in biosynthesis of the coenzyme pyrroloquinoline quinone. J. Bacteriology. 174:5814-5819.

Student¡@¾Gª÷ªQ
1986.9 - 1991.6
Professor¡@Chung-Ming Chang
Publications
1.Jeng, K.-S., Hu. C., and Chang, C. (1993). Hepatitis B core antigen forms oligomers and complexes with the P gene product in hepatitis B virus core particles. J. Gastroenterol. Hepatol. 8:S114-118.
2.Chiang, P.-W., Jeng, K.-S., Hu, C. and Chang, C. (1992). Characterization of a cis element required for packaging and replication of the human hepatitis B virus. Virology 186:701-711.
3.Ting, L.-P., Jeng, K.-S., Chou, C.-K., Su, T.-S., Hu, C. , Wong, F.-H., Chang, H.-K. and Chang, C. (1988) . Expression of oncogenes in human hepatoma cell lines. Chinese J. Microbiol. Immunol. 21:141-150.
4.Jeng, K.-S., Hu, C. and Chang, C. ( 1991) Differential formation of disulfide linkages in the core antigen of extracellular and intracellular hepatitis B virus core particles. J. Virol.65:3924-3927.

Student¡@³¯µ½¯Â
1986.9 - 1991.5
Professor¡@Cheng-Po Hu
Publications
1.Chen, S.-C., Chou, C.-K., Wong, F.-H., Chang, C., and Hu, C. (1991). Overexpression of epidermal growth factor and insulin-like growth factor-I receptors and autocrine stimulation in human esophageal carcinoma cells. Cancer Res. 51:1898-1903.
2.Wong, F.-H., Hu, C., Chen, S.-C., Yu, Y.-T. and Chang, C. (1992). Absence of genomes of DNA tumor viruses and expression of oncogenes and growth factors in two esophageal carcinoma cell lines of Chinese origin. Chinese J. Microbiol. Immunol. 25:59-68.
3.Liu, Y.-C., Chen, S.-C., Chang, C., Leu, C.-M. and Hu, C. (1996). Platelet-derived growth factor is an autocrine stimulator for the growth and survival of human esophageal carcinoma cell lines. Exp. Cell Res. 228:206-211.


1992

Student¡@¯ÎªâµØ
1984.9 - 1992.1
Professor¡@Chung-Ming Chang
Publications
1.Wong, F.-H., Liaw, Y.-F., Hu, C., Chao, Y., Chang, C. and Pao, C.-C. (1993). Analysis of the status of hepatitis B virus DNA in peripheral blood mononuclear cells of chronic hepatitis B patients. J. Gastroenterol. Hepatol. 8: S75-79.
2.Wong, F,-H., Hu, C., Chiu, J.-H., Huang, B.-S., Chang, J.-P., Lin, P.-J., Chien, K.-Y. and Chang , C. (1994). Expression of multiple oncogenes in human esophageal carcinomas. Cancer Invest.12:121-131.
3.Wong, F.-H., Hu, C., Chen, S.-C., Yu, Y.-T. and Chang, C. (1992). Absence of genomes of DNA tumor viruses and expression of oncogenes and growth factors in two esophageal carcinoma cell lines of Chinese origin. Chinese J. Microbiol. Immunol. 25:59-68.

Student¡@³¯²QÁø
1987.9 - 1992.6
Professor¡@Chung-Ming Chang
Publications
1.Chen, S.-H., Hu, C., and Chang, C. (1992). Hepatitis B virus replication in well differentiated mouse hepatocyte cell lines immortalized by plasmid DNA. Cancer Res. 52:1329-1335.
2.Chen, S.-H., Hu, C., Lee, C.-K. and Chang, C. (1993). Immune reactions against hepatitis B viral antigens lead to the rejection of hepatocellular carcinoma in BALB/c mice. Cancer Res.53:4648-4651.
3.Chang, P.-C., Hu, C., Chen, S.-H., Wang-Wuu, S. and Chang, C.(1995). Deletion of integrated hepatitis B virus genome and cellular flanking sequences in hepatocellular carcinoma cells in BALB/c mice. Hepatology 21:1504-1509.

Student¡@³ë¬îµØ
1987.9 - 1992.6
Professor¡@Ling-Pai Ting
Publications
1.Yuh, C.-H. and Ting, L.-P. (1993). Differentiated liver cell specificity of the second enhancer of hepatitis B virus. J. Virol. 67:142-149.
2.Yuh, C.-H., Chang, Y.-L. and Ting, L.-P. (1992). Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus. J. Virol. 66:4073-4084.
3.Yuh, C.-H. and Ting, L.-P. (1991). C/EBP-like proteins binding to the functional box-alpha and box-beta of the second enhancer of hepatitis B virus. Mol. Cell Biol. 11:5044-5052.
4.Yuh, C.-H. and Ting, L.-P. (1990). The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function. J.Virol. 64:4281-4287.
5.Chang, H.-K., Wang, B.-Y., Yuh, C.-H., Wei, C.-L. and Ting, L.-P. (1989). A liver-specific nuclear factor interacts with the promoter region of the large surface protein gene of human hepatitis B virus. Mol. Cell. Biol. 9: 5189-5197.


1993

Student¡@³\¥@©y
1988.9 - 1993.7
Professor¡@Szecheng J. Lo
Publications
1.Sheu, S,-Y. and Lo, S.-J. (1992). Preferential ribosomal scanning is involved in the differential synthesis of the hepatitis B viral surface antigens from subgenomic transcripts. Virology 188:353-7.
2.Lo, S.-J., Sheu, S.-Y. and Lin, C.-G. (1993). Translational regulation in the expression of hepatitis B viral genes. J. Gastroenterol. hepatol. 8S:45-53.
3.Sheu, S.-Y. and Lo, S.-J. (1994). Biogenesis of the hepatitis B viral middle (M) surface protein in a human hepatoma cell line: demonstration of an alternative secretion pathway. J. Gen. Virol. 75:3031-3039.
4.Sheu, S.-Y and Lo, S.-J. (1995) Deletion of alteration of hydrophobic animo acids at the first and the third transmembrane domains of hepatitis B surface antigen enhances its production in Escherichia coli. Gene. 160:174-184.
5.Sheu. S.-Y., Chen, K.-L., Lee Wu, Y.-H. and Lo, S.-J. (1996). No intermolecular interaction between the large hepatitis delta antigens is required for the secretion with hepatitis B surface antigen: a model of empty HDV particle. Virology 218:275-278.
6.Chang, H.-H., Sheu, S.-Y. and Lo, S.-J. (1999). Expression of foreign antigens on the surface of Escherichia coli by fusion to an outer member protein TraT. J. Biomed. Sci. 6:64-70.

Student¡@¬I«iºú
1985.9 - 1993.6
Professor¡@Szecheng J. Lo
Publications
1.Shih, Y.-L. Chou. S.-C., Chi, C.-S., Tchen, T.-T. and Lo, S.-J. (1990). Tropic effect of dexamethasone on goldfish melanocytoma cells: induction of calcium-dependent but protein synthesis-independent morphological changes. Life Sci. 47:313-318.
2.Shih, Y.-L., and Lo, S.-J. (1993). Induction of cell expansion of goldfish melanocytoma cells( GMM-1) by epinephrine and dexamethasone requires external calcium. Cell Biol. Inter.Rep.17:533-542.

Student¡@ªL²M®c
1988.9 - 1993.6
Professor¡@Szecheng J. Lo
Publications
1.Lin, C.-G. and Lo, S.-J. (1992). Evidence for involvement of a ribosomal leaky scanning mechanism in the translation of the hepatitis B virus Pol gene from the viral pregenome RNA. Virology 188:342-352.
2.Lo, S.-J., Sheu, S.-Y. and Lin, C.-G. (1993). Translational regulation in the expression of hepatitis B viral genes. J. Gastroenterol. Hepatol.8:45-53.
3.Lin, C.-G., You, L.-R. and Lo, S.-J. (1993). Expression and stability of hepatitis B pol protein in Escherichia coli. J. Gastroenterol. Hepatol. 8S:54-58.
4.Lin, C.-G., Yang, S.-J., Hwang, W.-L., Su, T.-S. and Lo, S.-J. (1995). Demonstration of the presence of protease-cutting site in the spacer of hepatitis B viral Pol protein. J. Virol. Meth.51:61-74.

Student¡@®}¤hÄõ
1987.9 - 1993.1
Professor¡@Chen-Kung Chou
Publications
1.Hsu, S.-L., Lin, Y.-F. and Chou, C.-K. (1992). Transcriptional regulation of transferrin and albumin genes by retinoic acid in human hepatoma cell line Hep3B. Biochem. J. 283:611-615.
2.Hsu, S.-L., Lin, Y.-F. and Chou, C.-K. (1993). Retinoic acid biphasically regulates the gene expression of hepatitis B virus surface antigen in human hepatoma Hep3B cells. J.Biol.Chem. 268:23093-23097.

Student¡@©P¯Âªâ
1987.9 - 1993.1
Professor¡@Carton Wen-sheng Chen
Publications
1.Chen, C.-W., Yu, T.-W., Chung, H.-M., and Chou, C.-F. (1992). Discovery and characterization of a new transposible element, Tn4811, in Streptomyxces lividans 66. J. Bacteriology. 174:7762-7769.
2.Chou, C.-F. and Chen, C.-W. (1992). arfJ mutations are highly inducible by ethidium bromide in pro B strains of Streptomyces lividans: Implication of pathway interactions. Biochemical Biophysical Research Communications.189:1101-1109.

Student¡@µÎ¨Øªå
1987.9 - 1993.4
Professor¡@Cheng-Po Hu
Publications
1.Shu, P.-Y., Chang, C., Hwang, L.-H. and Hu, C. (1993) Proliferative and cytotoxic T-cell clones recognize endogenously synthesized HBcAg in an asymtomatic HBsAg carrier. Hepatology 18:275-283.
2.Shu P.-Y., Lin, M.-Y., Chang, C., Hwang, L.-H., Huang, J.-H., Chang, T.-H. and Hu, C. (1994). Presence of hepatitis B surface antigen(HBsAg)-specific cytotoxic T cells in asymptomatic HBsAg carriers. J. Inf. Dis. 169:633-637.

Student¡@³¯©s¨}
1986.9 - 1993.6
Professor¡@Yu-Sun Chang
Publications
1.Chen, M.-L., Lee, Y-H. and Lo. S.-J. (1988) High-level production of hepatitis B virus (HBV) X protein in Escherichia coli using gene II promoter of M13. Gene 62:315-312.
2.Chang, Y.-S., Chen, M.-L., Su, R.-C., Shu, C.-H. and Liu, S.-T. (1992) Sequence analysis of the BZLF1 gene of Epstein-Barr virus derived from a new variant isolated in Taiwan. Nucleic Acids Res. 20-39.
3.Chen, M.-L., Tsai, C.-N., Huang, C.-L., Liang, C.-H., Shu, Sultzanu, D., Liu, S.-T. and Chang, Y.-S. (1992). Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein-Barr virus variant derived from the nasopharyngeal carcinomas in the Taiwanese population. Oncogne 7:2131-2140.
4.Tyan, Y.-S., Liu, S.-T., Ong, W.-R., Chen, M.-L., Shu, C.-H. and Chang, Y.-S. (1993). Detection of Epstein-Barr virus and human papillomavirus in head and neck tumors in Taiwan. J. Clinical. Microbiology 31:53-56.
5.Chen, M.-L., Wu, R.-C., Liu, S.-T. and Chang, Y.-S. (1995). Characterization of 5'-upstream sequences of the latent membrane protein 1 ( LMPI) gene of an Epstein-Barr virus identified in nasopharyngeal carcinoma tissues. Virus Res. 37:75-84.
6.Chen, M.-L., Hsu, N.-C., Liu, S.-T. and Chang, Y.-S. (1995). Identification of an internal promoter of the latent membrane protein I gene of Epstein-Barr virus. DNA and Cell Biol.14:205-211.
7.Jowett, J.-B., Planclles, V., Poon, B., Shah, N.-P., Chen, M.-L. and Cheng, Y.-S. (1995). The human immunodeficiency virus types 1 vpr gene arrests infected T cells in the G2-M phase of the cell cycle. J. Virol. 69(10):6304-6312.
8.Akkina, R.-K., Walton, R.-M., Chen, M-L., Li, Q-X. and Cheng, Y.-S. (1996). High-efficiency gene transfer into CD34++ cells with a human immunodeficiency virus type 1-based retroviral vector psudotyped with vesicular stomatitis virus envelope glycoprotein G. J. Virol .70(4):2581-2585.


1994

Student¡@³¯¨È¹p
1989.9 -1994.6
Professor¡@Rong-Tsun Wu
Publications
1.Chen, Y.-L. and Wu, R.-T. (1994). Altered quenine modification of transfer RNA involved in the differentiation of human erythroleukemia K562 cells in the presence of distinct differentiation inducers. Cancer Res. 54:2192-2198.


1995

Student¡@½²«Fªâ
1989.9 - 1995.2
Professor¡@Tsung-Sheng Su
Publications
1.Su, T.-S., Tsai, T.-F., Chi, C.-W., Han, S.-H. and Chou, C.-K. (1990). Elevation of the facilitated glucose transporter messenger RNA in human hepatocellular carcinoma. Hepatology 11, 119-122.
2.Tsai, T.-F., Hsiao, K.-J. and Su, T.-S. (1990). Phenylketonuria mutation in Chinese haplotype 44 identical with haplotype 2 mutation in Northern-European Caucasians. Hum Genet 84, 409-411.
3.Soong, B.-W., Tsai, T.-F., Su, C.-H., Kao, K.-P., Hsiao, K.-J. and Su, T.-S. (1991). DNA polymorphisms and deletion analysis of the Duchenne/Becker muscular dystrophy gene in Chinese. Am J Med Genet 38, 593-600.
4.Lin, C.-H., Hsiao, K.-J., Tsai, T.-F., Chao, H.-K. and Su, T.-S. (1992). Identification of a missense phenylketonuria mutation at codon 408 in the Chinese. Hum Genet 89, 593-596.
5.Lui, W.-Y., Peng, F.-K., Chang, Y.-F., Chang, T.-J., Tsai, T.-F., Hsu, M.-L., Su, T.-S., Tsay, S.-H., Wu, C.-W., Liu, T.-Y. and Chi, C.-W. (1993). Analysis of glucocorticoid receptors in human hepatocellular carcinoma and HepG2 cells. Hepatology 18, 1167-1174.
6.Tsai, T.-F. and Su, T.-S. (1995). A nuclear post-transcriptional event responsible for overproduction of argininosuccinate synthetase in a canavanine-resistant variant of a human epithelial cell line. Eur J Biochem 229, 233-238.
7.Wang, S.-Y., Chen, L.-Y., Tsai, T.-F., Su, T.-S., Choo, K.-B. and Ho, C.-K. (1996). Constitutive production of colony-stimulating factor(s) by human hepatoma cell lines: possible correlation with cell differentiation. Exp Hematol 24, 437-444.
8.Tsai, T.-F., Wu, M.-J. and Su, T.-S. (1998). Usage of cryptic splice sites in citrullinemia fibroblasts suggests role of polyadenylation in splice-site selection during terminal exon definition. DNA Cell Biol 17, 717-725.
9.Chao, H.-K., Tsai, T.-F., Lin, C.-S. and Su, T.-S. (1999). The study of the p53 codon 249 mutation suggests that activation of the ras gene may not be a major event in aflatoxin B1-related human hepatocarcinogenesis. Mol Carcinogen 26, 69-73.

Student¡@Á§¤@Ä«
1989.9 - 1995.6
Professor¡@Ming-Zong Lai
Publications
1.Lee, M.-R., Chung, C.-S., Liou, M.-L., Wu, M., Li, W-F, Hiseh, Y.-P. and Lai, M.-Z. (1992) Isolation and characterization of nuclear proteins that bind to TCR Vb promoter decamer motif. J. Immunol. 148:1906-1912.
2.Hsueh, Y.-P., Yang, Y.-F., Liang, H.-E., Han, S.-H. and Lai, M.-Z. (1995). Limited efficacy of T cell receptor-derived peptides to modulate T cell responses. Cell. Immunol. 154: 5675-5683.
3.Hsueh, Y.-P. and Lai, M.-Z. (1995). JNK but not MAP kinase is sensitive to cAMP in T lymphocytes. J. Biol. Chem. 270: 18094-18098.
4.Hsueh, Y.-P. and Lai, M-Z. (1995) Overexpression of ATF-I in activated and in transformed lymphocytes. J. Immunol. 154:5674-5683.
5.Hsueh, Y.-P., Liang, H.-E., Ng, S.-Y. and Lai, M.-Z. (1997) CD28 costimulation activates CREB in T lymphocytes. J. Immunol. 158:85-93.

Student¡@®]¥ú¿·
1991.9 - 1995.12
Professor¡@¼BªZ­õ
Publications
1.Sun, K.-H., Liu, W.-T., Tsai, C.-Y., Liao, T.-S., Lin, W.-M. and Yu, C.-L. (1992) Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum. Ann Rheu Dis. 51:707-712.
2.Lieu, C.-W., Liu, W.-T., Sun, K.-H. and Wang, S.-Y. (1993). Some special characteristic of the novel human promonocyte cell line, HL-CZ. J. Biomed. Lab. Sci. 5:196-204.
3.Liu, W.-T., Lee, T.-S., Sun, K.-H., Twu, S.-J., Shi, C.-H. and Wang, G.-R. (1994) The measurement for mRNA level of tumor necrosis factor-Ą from human immunodeficiency virus seropositive individuals. J Biomed Lab Sci. 1994;6:171-176. Sun, K.-H., Liu, W.-T., Tsai, C.-Y., Tang, S.-J., Han, S.-H. and Yu, C.-L. (1995). Anti-dsDNA antibodies cross react with the ribosomal P proteins expressed on the surface of glomerular mesangial cells to exert cytostatic effect. Immunology 85: 262-269.
4.Sun, K.-H., Liu, W.-T., Tang, S.-J., Tsai, C.-Y., Hsieh, S.-C., Wu, T.-H., Han, S.-H. and Yu, C.-L. (1996) The expression of acidic ribosomal phosphoproteins on the surface membrane of different tissues in autoimmune and normal mice which are the target molecules for anti-dsDNA antibodies. Immunolog 87: 362-371.

Student¡@³¯¤å©ú
1991.9 - 1995.6
Professor¡@Nan-Chi Chang
Publications
1.Chen, W.-M., Chang, A.-C., Shie, B.-J., Chang, Y.-H., and Chang, N.-C. (1992). Molecular cloning and characterization of a mouse a2C2 adrenoreceptor subtype gene. Biochem. Biophys. Acta. 1171:219-223.
2.Chang, Y.-H., Chang, N.-C., Chen, W.-M. and Chang, A.-C. (1993). Molecular characterization of a murine homologue of a2C4 adrenoreceptor subtype gene . Biochem. Mol. Biol. Internat. 29:467-474.
3.Chang, N.-C., Jenkins, N.-A., Gilbert, D.-J., Copeland, N.-G., Chang, Y.-H., Chen, W.-M. and Chang, A.-C. (1994). Assignment of two a2 adrenoceptor subtype genes to murine chromosomes. Neurosci. lett. 167:105-108.
4.Chen, W.-M., Chang, A.-C., Wang, C.-M., Lin, C.-C. and Chang, N.-C. (1996). Characterization of the regulatory region of murine a2C2 gene. Neuosci. Lett. 210:33-36.

Student¡@¶À¬LµÙ
1987.9 - 1995.6
Professor¡@Ching-Yuang Lin
Publications
1.Huang J.-L. and Lin C.-Y. (1994). A hereditary C3 deficiency due to aberrant splicing of exon 10. Clinical Immunol & Immunopathol 73: 267-273.

Student¡@ªL©ú¥P
1988.9 - 1995.1
Professor¡@Ming-Zong Lai
Publications
1.Lin-Feng, M.-H. and Lai, M.-Z. (1994). A peptide binding weakly to the major histocompatibility molecule augments T cell response. Eur. J. Immunol. 24:355-61.
2.Lin-Feng, M.-H., Shen, Y.-C., Lai, M.-Z. and Liaw, Y.-C. (1996). Selective contact on T cell receptor recognition. Intl. Immunol. 8:45-55.
3.Chang, R.-H., Lin Feng, M.-H., Liu, W.-H., Liu, W.-H. and Lai, M.-Z. (1997) Nitric oxide increased interleulin-4 expression in T lymphocytes. Immunology. 90:364-369.

Student¡@¥Õ¨ä©û
1990.9 - 1995.10
Professor¡@Ning-Hsing Yeh
Publications
1.Pai, C.-Y., Chen, H.-K., Sheu, H.-L. and Yeh, N.-H. (1995). Cell cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis. J. Cell Sci. 108:1911-1920.
2.Pai, C.-Y. and Yeh, N.-H. (1996). Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130. Biochem. Biophy. Res. Commun. 221:581-587.
3.Chen, H.-K., Pai, C.-Y., Huang, J.-Y. and Yeh, N.-H. (1999). Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structure organization. Mol. Cell. Biol. 19:8536-8546.


1996

Student¡@³¯±ù¤å
1989.9 - 1996.7
Professor¡@Shih-Tung Liu
Publications
1.Chen, L.-W., Lin, L.-S., Chang, Y.-S. and Liu, S.-T. (1995). Functional analysis of EA-D of Epstein-Barr virus. Virology. 1995; 211:593-7.

Student¡@¶À·çÄÖ
1989.9 - 1996.6
Professor¡@Chung-Ming Chang
Publications
1.Huang, R.-L., Chen, C.-C., Huang, Y.-L., Hsieh, D.-J., Hu, C., Chen, C.-F. and Chang, C. (1996) Osthole increase glycosylation of hepatitis B surface antigen and suppresses the secretion of hepatitis B virus in vitro. Hepatology. 24:508-515.

Student¡@§õ·ç¦~
1989.9 - 1996.7
Professor¡@Shih-Tung Liu
Publications
1.Li, S.-N., Chang, Y.-S. and Liu, S.-T.(1996). Effect of a 10 amino acid deletion on the oncogenic activity of latent membrane protein 1 of Epstein-Barr virus. Oncogene. 12:2129-2135.

Student¡@±iÅtªY
1990.9 - 1996.6
Professor¡@¶À¬L½¬
Publications
1.Chang, Y.-H., Hwang, J., Shang, H.-F. and Tsai, S.-T. (1996) Characterization of human DNA topoisomerase II as autoantigen recognized by patients with IDDM. Diabetes ( in press).

Student¡@®]¼w¬À
1990.9 - 1996.6
Professor¡@Nan-Chi Chang
Publications
1.Sun. D.-S., Chang, A.-C., Jenkins, N.-A., Gilbert, D.-J., Copeland, N.-G. and Chang, N.-C. (1996). Identification, molecular characterization and chromosomal localization of the cDNA encoding a novel leucine zipper motif-containing protein. Genomics. 36(1):54-62.

Student¡@±iµe¬Ü
1989.9 - 1996.10
Professor¡@Carton Wen-sheng Chen
Publications
1.Chang, H.-M., Chieh, Y.-T., Chen, M.-Y., Bibb, M.-J. and Chen, C.-W. (1996). The cut RS signaltransduction system of Streptomyces lividans represses the biosynthesis of a polyketide antibiotic actinorhodin. Molecular Microbiolgoy. 21:1075-1085.

Student¡@¼B¥Ã¶W
1990.9 - 1996.11
Professor¡@Cheng-Po Hu
Publications
1.Liu, Y.-C., Chen, S.-C., Chang, C., Leu, C.-M. and Hu, C.(1996). Platelet-derived growth factor is an autocrine stimulator for the growth and survival of human esophageal carcinoma cell lines. Exp.Cell Res.

Student¡@®}ªY§D
1989.9 - 1996.10
Professor¡@Ning-Hsing Yeh
Publications
1.Hsu, H.-L. and Yeh, N.-H. (1996). Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis. J. Cell Sci. 109:277-288.

Student¡@±i·s«J
1989.9 - 1996.11
Professor¡@Szecheng J. Lo
Publications
1.Chang, H.-H., Hu, S.-T., Huang, T.-F., Chen, S.-H., Lee-Wu, Y.-H. and Lo, S.-J.(1993). Rhodostomin, an RGD-containing peptide expressed from a synthetic gene in Escherichia coli facilitates the attachment of human hepatoma cells. Biochem. Biophys. Res. Commun. 190:242- 249.
2.Chang, H.-H., Chang, C.-P., Chang, J.-C., Dung, S.-Z. and Lo, S.-J. (1997). Application of recombinant rhodostomin in studying cell adhesion. J. Biomed. Sci. 4: 235-243.
3.Chang, H.-H., Tsai, W.-J. and Lo, S.-J. (1997). Glutathione S-transferase-rhodostomin fusion protein inhibits platelet aggregation and induces platelet shape change. Toxicon.35: 195-204.
4.Chang, H.-H. and Lo, S.-J. (1998). Full-spreading platelets induced by recombinant rhodostomin are via binding to integins and correlated with FAK phosphorylation. Toxicon. 36: 1087-1099.
5.Chang, H.-H., Sheu, S.-Y. and Lo, S.-J. (1999). Expression of foreign antigens on the surface of Escherichia coli by fusion to an outer membrane protein TraT. J. Biomed. Sci. 6:64-70.
6.Chang, H.-H., Lin, C.-H. and Lo, S.-J. (1999). Recombinant rhodostomin substrates induce transformation and active calcium oscillation in human platelets. Exp. Cell. Res. 250: 387-400.
7.Chang, H.-H. and Lo, S.-J. (2000). Modification with a phosphorylation tag of PKA in the TraT-based display vector of Escherichia coli. J. Biotech. 78: 115-122.
8.Chang, H.-H., Shih, K.-N. and Lo, S-J. (2000). Receptor-mediated endocytosis as a selection force to enrich bacteria expressin rhodostomin on the surface. J. Biomed. Sci. 7:42-50.


1997

Student¡@½²¤C¤k

Professor¡@Yu-Sun Chang
Publications
1.Chang, Y.-S., Lin, Y.-J., Tsai, C.-N., Shu, C.-H., Tsai, M.-S., Choo, K.-B. and Liu, S.-T. (1992). Detection of mutations in the p53 gene in human head and neck carcinomas by single strand conformation polymorphism analysis. Cancer Lett. 67: 167-174.
2.Chen, M.-L., Tsai, C.-N., Huang, C.-R., Liang, C.-L., Shu, C.-H., Sulitzanu, D., Liu, S.-T. and Chang, Y.-S. (1992). Presence of a specific Epstein-Barr virus variant in the nasopharyngeal carcinoma in the Taiwanese population. Oncogene. 7:2131-2140.
3.Tsai, C.-N., Liu, S.-T. and Chang, Y.-S. (1995). Identification of a novel promoter located within the Bam HI Q region of the Epstein-Barr virus genome for the EBNA 1 gene. DNA. Cell Biol. 14: 767-776.
4.Tsai, C.-N., and Lee, C.-M., Chien, C.-K., Kuo, S.-C. and Chang, Y.-S. (1999). Additive effect of Sp1 and Sp3 in regulation of the ED-L1E promoter of EBV LMP 1 gene in human epithelial cells. Virol. 261:288-294.
5.Chang, Y.-S. (2000). Transcription of Epstein-Barr virus nuclear antigen 1 promoter Qp is repressed by transforming growth factor£] via Smad 4 binding element in human BL cells. Vrol. 277:184-197.

Student¡@ù޳·ì

Professor¡@Ling-Pai Ting
Publications
1.Lo, W.-Y. and Ting, L.-P. (1994). Repression of enhancer II activity by a negative regulatory element in the Hepatitis B virus genome. J. Virol. 68:1758-1764.

Student¡@°ªªvµØ

Professor¡@Ling-Pai Ting
Publications
1.Kau, J.-H. and Ting, L-P. (1997). A serine-kinase-containing protein complex interacts with the terminal protein domain of polymerase of Hepatitis B virus. J. Biom. Sci. 4:155-161.
2.Kau, J.-H. and Ting, L.-P. (1998) Phosphorylation of the core protein of hepatitis B virus by a 46-kilodalton serine kinase. J. Virol. 72:3796-3803.


1998

Student¡@³¢·¶¨}

Professor¡@Ling-Pai Ting
Publications
1.Kuo, Y.-L. and Ting, L.-P. (1997). Differential regulation of major surface promoter in Hepatitis B virus. DNA. Cell. Biol.16:545-557.

Student¡@³¯¯E¤¯

Professor¡@Soo-Chen Cheng
Publications
1.Chen, H.-R., Hsu, M.-T. and Cheng, S.-C. (1995). Spheroplast preparation facilitates PCR screening of yeast sequence. BioTechniques 19:744-747.
2.Chen, H.-R., Jan, S.-P., Tsao, T.-Y., Sheu, Y.-J., Banroques, J. and Cheng, S.-C. (1998). Snt309p: a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultancously with or immediately after dissociation of U4 in the same manner as Prp19p. Mol. Cell. Biol. 18:2196-2204.
3.Tsai, W.-Y., Chow, Y.-T., Chen, H.-R., Huang, K.-T., Hong, R.-J., Jan, S.-P., Kuo, N.-Y., Tsao, T.-Y., Chen, C.-H. and Cheng, S.-C. (1999). Cef1p is a component of the Prp19p- associated complex and essential for pre-mRNA splicing. J. Bio. Chem. 274:9455-9462.
4.Chen, H.-R., Tsao, T.-Y., Chen, C.-H., Tsai, W.-Y., Her, L.-S., Hsu., M.-T. and Cheng, S.-C. (1999). Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing. Proc. Natl. Acad. Sci. USA. i96: 5406-5411.
5.Chen, C.-H., Tsai, W.-Y., Chen, H.-R., Wang, C.-H. and Cheng, S.-C. (2001) Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. J. Bio. Chem. 276:488-494.

Student¡@¼B¬É¤¸

Professor¡@Chung-Ming Chang
Publications
1.Liou, J.-Y., Jeng, K.-S., Lin, C.-G., Hu, C.-P. and Chang, C. (1998). A novel regulator inhibits HBV gene expression. J. Biomed. Sci. 5:343-354.

Student¡@§d¬ü½Ë

Professor¡@Shie-Liang Hsieh
Publications
1.Wu, M.-Y., Hsu,-T.L., Lin, W.-W., Campbell, R.D. and Hsieh, S.-L. (1997). Serine/ Threonine kinase activity associated with the cytoplasmic domain of the lymphotoxin-£]receptor in HepG2 cells. J. Biol. Chem. 272: 17154-17159.
2.Wu, M.-Y., Wang, P.-Y., Han, S.-H. and Hsieh, S.-L. (1999). The cytoplasmic domain of the lymphotoxin-£]receptor mediates cell death in Hela cells. J. Biol. Chem. 274: 1868-11873.

Student¡@§ùÂE¹B
1989.9 - 1998.7
Professor¡@Cheng-Po Hu
Publications
1.Dou, H.-Y., Wu, J.-C., Peng, W.-L., Chang, C., Chi, W.-K., Chu, Y.-D. and Hu, C. (1998). Analysis of T cell receptor VƒÒ gene usage during the course of disease in patients with chronic hapatitis B. J. Biomed. Sci. 5:428-434.

Student¡@±i¨K¶v

Professor¡@Shih-Tung Liu
Publications
1.Chang, P.-C., Chang, Y.-S. and Liu, S.-T. (1998). Characterization of the BcLF1 promoter in Epstein-Barr virus. J. Gen. Virol. 79:2003-2006.
2.Chang, P.-C. and Liu, S.-T. (2001). Function of the intercistronic region of the BRLF1-BZLF1 bicistronic mRNA in translation the Zta protein of the Epstein-Barr virus. J. Virol. 75:1142-1151.


1999

Student¡@ÃC§B¾±

Professor¡@Wan-Jr Syu
Publications
1.Yan, B.-S., Tam, M.-H. and Syu, W-J. (1998). Self-association of the C-terminal domain of the hepatitis-C virus core protein. Eur. J. Biochem. 258: 100-106.
2.Hsu, S.-C., Lin, H.-P., Wu, J.-C., Ko, K.-L., Sheen, I.-J., Yan, B.-S., Chou, C.-K. and Syu, W.-J. (2000). Characterization of a strain-specific monoclonal antibody to hepatitis delta virus antigen. J. Virological Methods. 87:53-62.
3.Lin, H.-P., Hsu, S.-C., Wu, J.-C., Sheen, I.-J, Yan, B.-S. and Syu, W.-J. (1999). Localization of isoprenylated antigen of hepatitis delta virus by anti-farnesyl antibodies. Journal of General Virology. 80:91-96.
4.Hsu, S.-C., Yan, B.-S., Pan, J.-M. and Syu, W.-J.(1997). A monoclonal antibody reacts with maltose binding protein of Escherichia coli and related enteric bacteria. Journal of Immunological Methods. 204:169-174.
5.Yan, B.-S., Lee, K.-M., Liu, S.-H. and Syu, W.-J. (1996). Characterization of monoclonal antibodies to the 26-kDa glutathione S-transferase of Schistosoma japonicum. Hybridoma. 15:429-433.
6.Yan, B.-S., Liao, L.-Y., Leou, K., Chang, Y.-C. and Syu, W.-J. (1994) Truncating the putative membrane association region circumvents the difficulty of overproducing hepatitis C virus protein E1 in Escherichia coli. J. Virol. Methods. 49: 343-352.

Student¡@«\ªQ¨}

Professor¡@Wan-Jr Syu
Publications
1.Yu, S.-L., Ko, K.-L., Chen, C.-S., Chang, Y.-C. and Syu, W.-J. (2000) Characterization of the distal tail fiber locus and determination of the receptor for phage AR1 that specifically infects E. coli O157:H7. J. Bacteriol. 182:5962-5968.
2.Chang ,Y.-C., Yu, S.-L. and Syu, W.-J. (1999). Organization of HIV-1 pol is critical for the Pol polyprotein processing. J. Biomedical Sci. 6: 333-341.
3.Yu, S.-L., Ding, H.-C., Seah, J.-N., Wu, K.-M., Chang, Y,-C., Chang, K.-S., Tam, M.- F. and Syu, W.-J. (1998) Characterization of a phage specific to hemorrhagic Escherichia coli O157:H7 and disclosure of variations in host outer membrane protein OmpC. J. Biomedical Science 5: 370-382.
4.Yu, S.-L., Chou, Wang, N., Liou, C.-Y. and Syu, W.-J. (1995). Assay of HIV-1 protease activity by use of crude preparations of enzyme and biotinylated substrate. J. Virol. Methods. 53: 63-73.
5.Sun, C.-M., Yu, S.-L., Ou, J.-C. and Syu, W.-J. (1995). Test of the biflavones from Selaginella moellendorffii on the in vitro inhibition of HIV-1 protease. J. Chin. Med. 6: 223-230.
6.Yu, S.-L., Chou, M.-J., Tam, M.-F., Lee, T.-H. and Syu, W.-J. (1993) Expression and antigenicity of human immunodeficiency virus type-1 transmembrane gp41 in insect cells. Biochem. and Biophy. Res. Communications . 191: 207-213.

Student¡@±i·ß©¾

Professor¡@Wan-Jr Syu
Publications
1.Yu, S.-L., Ko, K.-L., Chen, C.-S., Chang, Y.-C. and Syu, W.-J. (2000). Characterization of the distal tail fiber locus and determination of the receptor for phage AR1 that specifically infects E. coli O157:H7. J. Bacteriol. 182:5962-5968.
2.Chang ,Y.-C., Yu, S.-L. and Syu, W.-J. (1999). Organization of HIV-1 pol is critical for the Pol polyprotein processing. J. Biomedical Sci. 6: 333-341.
3.Yu, S.-L., Ding, H.-C., Seah, J.-N., Wu, K.-M., Chang, Y,-C., Chang, K.-S.-S., Tam, M.-F. and Syu, W.-J. (1998). Characterization of a phage specific to hemorrhagic Escherichia coli O157:H7 and disclosure of variations in host outer membrane protein OmpC. J. Biomedical Science. 5: 370-382.
4.Chang, Y.-C., Ching, T.-T. and Syu, W.-J. (1996). Assaying the activity of HIV-1 integrase with DNA-coated plates. J. Virol. Methods. 59: 135-140.
5.Yan, B.-S., Liao, L.-Y., Leou, K., Chang, Y.-C. and Syu, W.-J. (1994) Truncating the putative membrane association region circumvents the difficulty of overproducing hepatitis C virus protein E1 in Escherichia coli. J. Virol. Methods 49: 343-352.

Student¡@½²ºû¨|

Professor¡@Soo-Chen Cheng
Publications
1.Tsai, W.-Y., Chow, Y.-T., Chen, H.-R., Huang, K.-T., Hong, R.-I., Jan, S.-P., Kuo, N.-Y., Tsao, T.-Y., Chen, C.-H. and Cheng, S.-C. (1999). Cef1p is a component of the Prp19p- associated complex and essential for pre-mRNA splicing. J. Bio. Chem. 274:9455-9462.
2.Chen, H.-R., Tsao, T.-Y., Chen, C.-H., Tsai, W.-Y., Her, L.-S., Hsu., M.-T. and Cheng, S.-C. (1999). Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing. Proc. Natl. Acad. Sci. USA i96: 5406-5411.
3.Chen, C.-H., Tsai, W.-Y., Chen, H.-R., Wang, C.-H. and Cheng, S.-C. (2001) Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. J. Biol. Chem. 276:488-494.

Student¡@³¯ªl·_
1994.9 - 1999.7
Professor¡@Ning-Hsing Yeh
Publications
1.Pai, C.-Y., Chen, H.-K., Hsu, H.-L. and Yeh, N.-H. (1995).Cell cycle-dependent alteractions of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis. J. Cell. Sci. 108:1911-1920.
2.Chen, H.-K. and Yeh, N.-H. (1997). The nucleolar phosphoprotein p130 is a GTPase/ ATPase with intrinsic property to form large complexes triggered by F- and Mg2+. Biochem. Biophys. Res. Commun. 230:370-375.
3.Chen, H.-K., Pai, C.-Y., Huang, J.-Y. and Yeh, N.-H. (1999). Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structure organization. Mol. Cell. Biol. 19:8536-8546.

Student¡@¾Gª÷¯q

Professor¡@ªL­Zºa
Publications
1.Cheung, J.-I., Wang, Y.-R. and Lin, A. (1996). Substrate specificity of monomeric and dimeric £\-sarcin. FEBS Lett. 386:60-64.
2.Cheung, J.-I. and Lin, A. (1999). Probing surface structure of sarcin domain on ribosomes of Escherichia coli by complementary oligo DNAs and ribosome-inactivating protein. J. Biom. Sci.

Student¡@³\®a°¶

Professor¡@Szecheng J. Lo
Publications
1.Hui, EKW. and Lo, S.-J. (1998). Dose the latency associated transcsript (LAT) of herpes simplex virus (HSV) function as a ribozyme during viral reaction. Virus Genes. 16: 147-148.
2.Hui, Ekw., Wang, P.-C. and Lo, S.-J. (1998). Strategies to clone unknown cellular flanking DNA sequence from the foreign integrant. Cell. Mol. Life. Sci. 54:1-9.
3.Hui, EKW., Chen, K.-L. and. Lo, S.-J. (1999). Hepatitis B virus core proteins with a C-terminal substitition of arginine- or lysine- stretch impair the function of pregenome recruitment. J. Gen. Virol. 80: 2661-2671.
4.Hui, EKW., Yi, Y.-S. and Lo, S.-J. (1999). Hepatitis B viral core proteins with an amino-terminal extension can assemble into core-like particles but can not be enveloped. J. Gen. Virol. 80: 2647-2659.
5.Wang, P.-C., Hui, EKW., Chiu, J.-H. and Lo, S.-J. (2000). Analysis of integrated hepatitis B virus DNA and flanking cellular sequence by inverse polymerase chain reaction. J. Virol. Method. 92: 83-90.

Student¡@³¯§Ó»¨

Professor¡@¼BªZ­õ
Publications
1.Chan, C.-H., Wu, M.-C., Huang, C.-T., Wu, K.-G. and Liu, W.-T. (1999). Genetic Characterization of the Hemagglutinin of two strains of influenza B virus co-circulated in Taiwan. J. Med. Virol. 59: 208-214.

Student¡@§f¬K±Ó
1994.9 - 2000.1
Professor¡@Cheng-Po Hu
Publications
1.Leu, C.-M., Chang, C. and Hu, C. (2000). Epidermal growth factor (EGF) supresses staurosporine-induced apoptosis by induving mcl-1 via the mitogen-activated kinase pathway. Oncogene 19:1665-1675.

Student¡@ªL»A«~

Professor¡@Shih-Tung Liu
Publications
1.Lin, T.-P., Chen, C.-L., Chang, J., Tschen, S.-M. and Liu, S.-T. (1999). Functional and transcriptional analyses of a fengysin synthetase gene, fenC, from Bacillus subtilis. J. Bacteriol. 181:5060-5067.

Student¡@¬x¤d´f

Professor¡@Shih-Tung Liu
Publications
1.Hung, C.-H., Kwan, M.-J. and Liu, S.-T. (1999). A cosmid system for the analysis of lytic replication of Epstein-Barr virus. Anal. Biochem. 272:277-280.
2.Hung, C.-H. and Liu, S.-T. (1999). Characterization of the Epstein-Barr virus BALF2 promoter. J. Gen. Virol. 80:2747-2750.


2000

Student¡@±ç¿KÀs

Professor¡@Yu-Sun Chang
Publications
1.Chang, M.-H., NG, C.-K., Lin, Y.-J., Liang, C.-L., Chung, P.-J., Chen, M.-L., Tyan, Y.-S., Hsu, C.-Y., Shu, C.-H., and Chang, Y.-S. (1997). Identification of a promoter for latent membrane protein 1 gene of Epstein-Barr virus that is specifically activated in human epithelial cells. DNA. Cell. Biol. 16:929-937.
2.Liang, C.-L., Tsai, C.-N., Chung, P.-R., Sun, C.-M., Chen, J.-L., Chen, R.-H. and Chang, Y.-S. (2000). Transcription of Epstein-Barr virus nuclear antigen 1 promoter Qp is repressed by transforming growth factor£] via Smad 4 binding element in human BL cells. Vrol. 277:184-197.

Student¡@¶À¬î®e

Professor¡@Ling-Pai Ting
Publications
1.Huang, C.-J., Che, Y.-H. and Ting, L.-P. (2000). Hepatitis B virus core protein interacts with the c-terminal region of actin-binding proein. J. Biom. Sci. 7: 160-168.

Student¡@¶À´fÄõ

Professor¡@Chung-Ming Chang
Publications
1.Huang, H.-L., Jeng, K.-S., Hu, C.-P., Tsai, C.-H., Lo, S.-J. and Chang, C. (2000). Identification and characterization of a structural protein of hepatitis B virus: a polymerase and surface fusion protein encoded by a spliced RNA. Virol. 275: 398-410.

Student¡@¦ó©vÅv

Professor¡@Chung-Ming Chang
Publications
1.Ho, T.-C., Jeng, K.-S., Hu, C.-P. and Chang, C. (2000). Effects of genomic length on translocation of Hepatitis B virus polymerase linked oligomer. J. Virol. 74: 9010-9018.

Student¡@­J­Û

Professor¡@ªL­Zºa
Publications
1.Huang, K.-C., Hwang, Y.-Y., Hwu, L. and Lin, A. (1997). Characterization of a new ribotoxin gene (c-sar) from aspergillus clavatus. Toxicon. 35: 383-392.
2.Lin, A., Huang, K.-C., Hwu, L. and Tzean, S.-S. (1995). Production of type II ribotoxins by aspergillus species and related fungi in Taiwan. Toxincon. 33: 105-110.
3.Hwu, L., Huang, K.-C., Chen, D.-T. and Lin, A. (2000). The action mode of the ribosome-inactivating protein £\-sarcin. J. Biomed. Sci. 7: 420-428.

Student¡@³¯©Àºa

Professor¡@Shie-Liang Hsieh
Publications
1.Hsieh, S.-L., Chen, N.-J., Tarbell, K., Liao, N.-S., Lai, Y.-G., Lee, K.-H., Lee, K.-M., Wu, S.-C., Sytwu, H.-K., Han, S.-H., and McDevitt, H. (2000). Transgenic mice expression surface markers for IFN-£^and IL-4 producing cells. Molecular. Immunology. 37: 281-293.
2.Chen, N.-J., Huang, M.-W. and Hsieh, S.-L. (2001) Enhanced secretion of interferon-gamma by activated Th1 cells occurs via reverse signaling through TNF-related activation-induced cytokine. J. Immunology. 166:270-276.

Student¡@·¨µÏ¶v

Professor¡@Chi-Hung Lin
Publications
1.Yang, S.-C., Huang, C.-H., Chen, N.-J., Chou, C.-K. and Lin, C.-H. (2000). Functional implication of human serine/ threonine kinase, hAlk, in cell cycle progression. J. Biomed. Sci. 7:484-493.

Student¡@³¯¿P¹ü

Professor¡@Chi-Hung Lin
Publications
1.Chen, Y.-J., Ko, J.-Y., Chen, P.-J., Shu, C.-H., Hsu, M.-T., Tsai, S.-F. and Lin, C.-H. (1999). Chromosomal aberrations in nasopharyngeal carcinoma analyzed by comparative genomic hybidization. Genes, Chromosomes & Cancer. 25(2):169-75.


2001

Student¡@³\³Ó³Ç

Professor¡@Wan-Jr Syu
Publications
1.Hsu SC, Syu WJ, Ting LT, and Wu JC. (2000) Immunohistochemical differentiation of hepatitis D virus genotypes Hepatology 32, 1111-1116.
2.Hsu SC, Lin HP, Wu JC, Ko KL, Sheen IJ, Yan BS, Chou CK, and Syu WJ. (2000) Characterization of a strain-specific monoclonal antibody to hepatitis delta virus antigen. Journal of Virological Methods, 87, 53-62.
3.Lin HP, Hsu SC, Wu JC, Sheen IJ, Yan BS, and Syu WJ. (1999) Localization of isoprenylated antigen of hepatitis delta virus by anti-farnesyl antibodies. J. Gen. Virol. 80, 91-96.

Student¡@³¯ª´¼ä

Professor¡@Shie-Liang Hsieh
Publications
1.Chen MC, Hsu TL, Luh TY, Hsieh SL. (2000). Overexpression of bcl-2 enhances LIGHT- and interferon-gamma -mediated apoptosis in Hep3BT2 cells. J Biol Chem. Dec 8;275(49):38794-801.


2002

Student¡@®}»A¬Â

Professor¡@Shie-Liang Hsieh
Publications
1.Hsu TL, Chang YC, Chen SJ, Liu YJ, Chiu AW, Chio CC, Chen L, Hsieh SL. Modulation of dendritic cell differentiation and maturation by decoy receptor 3. J Immunol. 2002 May 15;168(10):4846-53.

Student¡@¤ý²ÐÂE

Professor¡@Shiau-Ting Hu
Publications
1.Wang SH, Syu WJ, Huang KJ, Lei HY, Yao CW, King CC, Hu ST. Intracellular localization and determination of a nuclear localization signal of the core protein of dengue virus. J Gen Virol. 2002 Dec;83(Pt 12):3093-102.


2003

Student¡@³¢·çµY

Professor¡@¼BªZ­õ
Publications
1.Kuo RL, Kung SH, Hsu YY, Liu WT. Infection with enterovirus 71 or expression of its 2A protease induces apoptotic cell death. J Gen Virol. 2002 Jun;83(Pt 6):1367-76.

Student¡@Á­§µØ

Professor¡@Yu-Sun Chang
Publications
1.Hsieh YH, Wu CJ, Chow KP, Tsai CL, Chang YS. Electroporation-mediated and EBV LMP1-regulated gene therapy in a syngenic mouse tumor model. Cancer Gene Ther. 2003 Aug;10(8):626-36.

Student¡@ªL¯À¬Ã

Professor¡@Cheng-Po Hu
Publications
1.Lin SJ, Shu PY, Chang C, Ng AK, Hu CP. IL-4 suppresses the expression and the replication of hepatitis B virus in the hepatocellular carcinoma cell line Hep3B. J Immunol. 2003 Nov 1;171(9):4708-16.

Student¡@¸â¥@ÄP

Professor¡@Soo-Chen Cheng
Publications
1.Chan SP, Kao DI, Tsai WY, Cheng SC. The Prp19p-associated complex in spliceosome activation. Science. 2003 Oct 10;302(5643):279-82. Epub 2003 Sep 11.


2004

Student¡@¼B°¶¼s

Professor¡@Chen-Kung Chou
Publications
1.Liu WK, Yen PF, Chien CY, Fann MJ, Su JY, Chou CK. The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappa-B and potentiate apoptosis. Biochem J. 2004 Mar 15;378(Pt 3):867-76.

2005  


Student¡@³s°¶¨k
2000.9-2005.9
Professor¡@
Chi-Hung Lin
Publications
Wei-Nan Lian, TZU-Wei Wu, Ro-Lan Dao, Yann-Jang Chen, Chi-Hung Lin. Deglycosylation of Na+/K+-ATPase causes the basolateral protein to undergo apical targeting in polarized hepati
c cells. J Cell Sci. 2006 Jan 1;119(Pt 1):11-22. Epub 2005 Dec 8.

Student¡@ªô¯E³Ç
2001.9-2005.9

Professor¡@Wan-Jr Syu
Publications
1. Chiu, H.-J.,Lin, W.-S. and Syu, W.-J. Type III Secretion of  EspB in enterohemorrhagic Escherichia coli 0157:H7.Arch Microbiol 180:218-226(2003)

2. Chiu HJ, Syu WJ (2005) Functional analysis of EspB from enterohemorrhagic Escherichia coli. Microbiology 151, 3277-3286.

Student¡@±i·ç½@
1999.9-2005.9
Professor¡@
Szecheng J. Lo
Publications
Chang JC, Chang HH, Lin CT, Lo SJ. The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets. J Biomed Sci. 2005 Dec;12(6):881-98. Epub 2005 Oct 14.

Student¡@§d¿o·¶
1999.9-2005.9
Professor¡@
Ming-Zong Lai
Publications
Wu YY, Chang YC, Hsu TL, Hsieh SL, Lai MZ. Sensitization of cells to TRAIL-induced apoptosis by decoy receptor 3. J Biol Chem. 2004 Oct 15;279(42):44211-8.

Student¡@Ĭ¤åµY
1997.9-2005.2
Professor¡@
Shie-Liang Hsieh
Publications
Yang CR, Hsieh SL, Teng CM, Ho FM, Su WL, Lin WW. Soluble decoy receptor 3 induces angiogenesis by neutralization of TL1A, a cytokine belonging to tumor necrosis factor superfamily and exhibiting angiostatic action. Cancer Res. 2004 Feb 1;64(3):1122-9.

Student¡@½²¨ÎÀs
2000.9-2005.2
Professor¡@
Yu-Sun Chang
Publications
Hsieh YH, Wu CJ, Chow KP, Tsai CL, Chang YS. Electroporation-mediated and EBV LMP1-regulated gene therapy in a syngenic mouse tumor model. Cancer Gene Ther. 2003 Aug;10(8):626-36.

Student¡@¼B¤å½å
1998.9-2005.1
Professor¡@
Ming-Zong Lai
Publications

Liu, W.-H., and Lai, M.-Z. Deltexl regulates T-cell activation by targeted degradation of active MEKK1. Mol. Cell. Biol. 2005. Feb. 25(4):1367-1378.


2006 


Student¡@³¯®¶ÝÂ
2000-2006
Professor¡@
Wan-Jr Syu
Publications
1. Tsai NP, Wu YC, Chen JW, Wu CF, Tzeng CM, Syu WJ. (2006). Multiple functions of l0036 in the regulation of the pathogenicity island of enterohemorrhagic Escherichia coli O157:H7. Biochemical Journal 393, 591-599.
2. Chen JW, Sun CM, Sheng WL, Wang YC, Syu WJ. (2006). Expression analysis of up-regulated genes responding to plumbagin in Escherichia coli. Journal of Bacteriology. 188, 456-63.

¡@

Student¡@ੱdÁÚ
1999-2006
Professor¡@
Yu-Sun Chang
Publications
Role of BRAMI in BMP signaling examined in zebrafish model and cell line

Student¡@³¯©÷³Ç
2000.9-2006.4
Professor¡@
Shiau-Ting Hu
Publications
1. Tsay, Y-G., Chen, C.-C., Hu, S.-T.,Identificaton of the-1 translational frameshift  sites using a liquid chromatography-tandem mass spectrometric approa. Anal. Biochem. 339(2005)83-93.
2. Chen, C.-C., and Hu, S.-T. Two frameshift products involved in the transposition of Bacterial Insertion Sequence IS629. J. of  Biol. Chem.Vol..281.No.31, pp21617-28, 2006.

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Student¡@¼B¯E«Ì (Hao-Ping Liu)
2000.9~2006.9
Professor¡@
Yu-Sun Chang
Publications

1. Liu HP, Wu CC, and Chang YS (2006) PRA1 promotes the intracellular trafficking and NF-kapa B signaling of EBV latent membrane protein 1. EMBO J 25(17): 4120-4130.
2. Hsieh YH*, Liu HP*, Lo SJ, and Chang YS (2006) Tumor regression by expression of high physiological levels of EBV latent membrane protein 1. Cancer Biol Ther 5(3): 310-317.  (*co-first author)
3. Chow KP, Lu HC, Chou HF, Liu HP, Hsieh SL, Chang YS, and Choo KB (2002) Induction of chemosensitivity in nasopharyngeal carcinoma cells using a human papillomavirus regulatory sequence and the thymidine kinase gene. J Biomed Sci 9(1): 41-46.

Student¡@±i¥Ã¸R
2001.9-2006.6
Professor¡@
Shie-Liang Hsieh
Publications
1. Chang, Y. C., Hsu, T. L., Lin, H. H., Chio, C. C., Chiu, A. W., Chen, N. J., Lin, C. H., and Hsieh, S. L. (2004). Modulation of macrophage differentiation and activation by decoy receptor 3. J Leukoc Biol 75, 486-494.

2. Chang, Y. C., Chan, Y. H., Jackson, D. G., and Hsieh, S. L. (2006). The glycosaminoglycan- binding domain of decoy receptor 3 (DcR3) is essential for induction of monocyte adhesion. J Immunol 176, 173-180.


Student¡@·¨´¼«i
1999.9-2006.2

Professor¡@
Ling-Pai Ting
Publications
Chih-Yung Yang, Tzu-Hsing Kuo, Ling-Pai Ting. Human Hepatitis B Viral e Antigen Interacts with Cellular Interleukin-1 Receptor Accessory Protein and Triggers Interleukin-1 Response, J. Biol. Chem. 2006 Nov 10;281(45):34525-34536..