王興雯 助理教授

Hsing-Wen Wang, Ph. D.

　

Assistant Professor, Institute of Biophotonics,

National Yang-Ming University, Taipei, Taiwan

　

Phone: 886-2-28267378

Fax: 886-2-2823-5460

email: hwwang2@ym.edu.tw

　

　
Biography:

Prof. Wang received her B.S. degree in physics from National Tsing Hua University, Taiwan, R.O.C., the M.S. degree in astronamy from Case Western Reserve University(CWRU), Cleveland, OH, USA, and the Ph.D. degree in biomedical  engineering from CWRU, in 1999. Before joining the faculty, she was a Research Associate with Department of Physics and Astronomy, Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, from 2001 to 2006(Advisor: Professor Arjun G. Yodh, Ph.D.). She is currently an Assistant Professor of Institute of Biophotonics, National Yang-Ming University, Taipei, Taiwan, R.O.C. Her research interests include oximetry, photodynamic therapy, tumor physiology, spectroscopy and microscopy, and optical coherence tomography.

Honors & Awards:

2004 Travel Award, Optical Society of America Topical Meeting,

        April 14-17 2004, Miami, FL
2003 Travel Award, American Society of Photobiology annual meeting,

        July 5-9 2003,Baltimore, MD
2003 Travel Award, SPIE-the International Society for Optical Engineering Photonics West,
        January 25-31, 2003, San Jose, CA
2002 Young Investigator Award Final List, American Association of Physicists in Medicine

        Meeting, July 12-19 2002, Montreal, Canada
2000 Technical Merit Award, Cytometrics Inc., Philadelphia Pennsylvania
1996 Travel Award, Optical Society of America Topical Meeting,

        March 20-22 1996, Orlando,FL
1995-1999 Olympus Research Graduate Fellowship, CWRU, OH
1992-1993 J. Nassau Fellowship in Astronomy, CWRU, OH
1986-1990 National Science Council Scholarship for Outstanding Students,
                 NTHU, Hsing Tsu, Taiwan

　

Professional Activities:


2003-present Member of America Photobiology Society
1997-present Member of Optical Society of America
1999-present Member of International Society for Optical Engineering
1998-1999 Reviewers for Gastrointestinal Endoscopy and Journal of Biomedical Optics
　

　
Selected Publications:

1. H. M. Ross, J. A. Smelstoys, G. J. Davis, A. S. Kapatkin, F. Del Piero, E. Reineke, H.-W.Wang, T. C. Zhu, T. M. Busch, A. G. Yodh, and S. M. Hahn, “Photodynamic therapy with Motexafin lutetium for rectal cancer: a preclinical model in the dog,” J. Surgical Research 2006, in press.


2. G. Yu, T. Durduran, C. Zhou, H.-W. Wang, M. E. Putt, H. M. Saunders, C. M. Sehgal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic
efficacy,” Clinical Cancer Research, 11(9), 3543-3552, 2005.

3. H.-W. Wang, T. C. Zhu, M. E. Putt, M. Solonenko, J. Metz, A. Dimofte, J. Mile, D. Fraker, E. Glatstein, S. M. Hahn, and A. G. Yodh, “In-vivo measurements of optical and physiological properties in human intraperitoneal tissues before and after photodynamic therapy,” J Biomedical Optics 10(1), 014004, 2005.
　

4. H.-W. Wang, M. E. Putt, M. J. Emanuele, D. B. Shin, A. G. Yodh, and T. M. Busch,
“Treatment-induced changes in tumor oxygenation predict photodynamic therapy outcome,” Cancer Res., 64(20): 7553-7561, 2004.
　

5. M. Solonenko, R. Cheung, T. M. Busch, A. Kachur, G. M. Griffin, T. Vulcan, T. C. Zhu, H.W. Wang, S. M. Hahn, and A. G. Yodh, “In-vivo reflectance measurement of optical properties, blood oxygenation and motexafin lutetium uptake in canine large bowels, kidneys, and prostates,” Phys. Med. Biol., 47(6): 857-873, 2002.


6. N. S. Trivedi, H.-W. Wang, A.-L. Nieminen, N. L. Oleinick, and J. A. Izatt, “Quantitative Analysis of Pc4 Localization in Mouse Lymphoma (LY-R) Cells via Double-Label Confocal Fluorescence Microscopy,” Photochem. Photobiol., 71(5): 634-639, 2000.
　

7. H.-W. Wang, J. Willis, M. I. Canto, M. V. Sivak, and J. A. Izatt, “Quantitative laser Scanning Confocal Autofluorescence Microscopy of Normal, Premalignant, and Malignant Colonic Tissues,” IEEE Transactions on Biomedical Engineering, 46(10): 1246-1252, 1999.
　

8. K. M. Heiskanen, M. B. Bhat, H.-W. Wang, J. Ma, and A.-L. Nieminen, “Mitochondrial Depolarization Accompanies Cytochrome c Release during Apoptosis in pc6 Cells,” J. Biol. Chem., 274(9): 5654-5658, 1999.
　

9. J. A. Izatt, M. D. Kulkarni, H.-W. Wang, K. Kobayashi, M. V. Sivak, “Optical Coherence Tomography and Microscopy in Gastrointestinal Tissues,” invited paper in IEEE Journal of Selected Topics in Quantum Electronics, 2(4): 1017-1028, 1996.

Chapter in Books:

1. H.-W. Wang and J. A. Izatt, “Optical Coherence Microscopy,” in Handbook of Optical Coherence Tomography, B. Bouma, G. Tearney, Eds., Marcel Dekker, New York, 2001.
　

Full-length conference proceedings:

1. H.-W. Wang, T. C. Zhu, M. Solonenko, S. M. Hahn, J. Metz, A. Dimofte, J. Mile, and A. G. Yodh, “In vivo measurements of penentration depth, oxygenation, and drug concentration using broadband absorption spectroscopy in human tissues before and after photodynamic therapy,” In: Proceedings of SPIE-The International Society for Optical Engineering, 4952: 68-75, 2003.
　

2. G. Yu, T. Durduran, T. M. Busch, H.-W. Wang, C. Zhou, H. M. Saunders, C. M. Sehgal, and A. G. Yodh, “Non-invasive monitoring hemodynamic responses in RIF tumors during and after PDT,” In: Proceedings of SPIE-The International Society for Optical Engineering, 4952: 131-139, 2003.

3. V. Westphal, H.-W. Wang, and J. A. Izatt, in Conference on lasers and Electro-Optics
(CLEO), Vol. 56 of OSA Trends in Optics and Photonics Series (optical Society of America, Washington, D. C. 2001), 331-332.

4. H.-W. Wang, A. Rollins, N. Trivedi and J. A. Izatt, “Real-Time Full-Field Optical Coherence Microscopy,” In: Proceedings of SPIE-The International Society for Optical
Engineering,3598: 204-212, 1999.
　

5. H.-W. Wang, J. Willis, M. I. Canto, M. V. Sivak, and J. A. Izatt, “Correlation of
autofluorescence to proliferation and inflammatory indices in human premalignant colonic
tissues,” Biomedical Optical Spectroscopy and Diagnosis, Trends in Optics and Photonics
Series (Optical Society of America, Washington D. C. 1998) 22: 73-75.
　

Patent in progress:


H.-W. Wang, A. Perkins, W. Groner, G. Fletcher, “Apparatus and Method to Achieve a Linear Optical Measurement (OD) of Hb Concentration or Hematocrit in Whole Blood using Diffuse Illumination,” in process, 2003.