Teh-Ying Chou

    PhD. Biochemistry, Cell and Molecular Biology, the Johns Hopkins University School of Medicine

Research

Molecular pathology and glycobiology of lung cancer.

(Ongoing Research: Molecular profiling of in situ, invasive and metastatic lung carcinomas with laser capture microdissection and cDNA microarray)

Pathology and pathogenesis of pulmonary and mediastinal diseases.

(Ongoing Research: Histopathologic and molecular analyses of acute interstitial pneumonia)

Publications

  1. Li, X.M., Chopra, R.K., Chou, T.Y., Schofield, B.H., Wills, K.M. and Huang, S.K. Mucosal IFN-g gene transfer inhibits pulmonary allergic responses in mice. Journal of Immunology 157(8):3216-9, 1996

  2. Jin, Y.T., Tsai, S.T., Li, C., Chang, K.C., Yan, J.J., Chao, W.Y., Eng, H.L., Chou, T.Y., Wu, T.C. and Su, I.J. Prevalence of human papillomavirus in middle ear carcinoma associated with chronic otitis media. American Journal of Pathology 150(4):1327-33, 1997

  3. Sherwood, J.B., Carlson, J.A., Gold, M.A., Chou, T.Y., Isacson, C., and Talerman, A. Squamous metaplasia of the endometrium associated with HPV 6 and 11. Gynecologic Oncology 66(1):141-5, 1997

  4. Chou, T.Y. and Hart, G.W. O-linked N-acetylglucosamine and cancer. The Molecular Immunology of Complex Carbohydrates-II, edited by Albert M. Wu. Plenum Press-New York, 2001

  5. Small, G.W., Chou, T.Y., Dang, C.V., and Orlowski, R.Z. Evidence for involvement of calpain in c-Myc proteolysis in vivo. Archives of Biochemistry and Biophysics 400:151-61, 2002

  6. Chou, T.Y., Chiu, C.H., Li, L.H., Hsiao, C.Y., Tzen, C.Y., Chang, K.T., Chen, Y.M., Perng, R.P., Tsai, S.F., Tsai, C.M. Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for Gefitinib treatment in patients with non-small cell lung cancer. Clinical Cancer Research 2005 (in press)